Cited by 367Tendon Structure and TreatmentKnee injuries and reconstruction techniquesSports injuries and prevention

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Medial collateral ligament healing: A multidisciplinary assessment in rabbits

Frank, C., Woo, S.L.-Y., Amiel, D., Harwood, F., Gomez, M., Akeson, W.·1983·The American Journal of Sports Medicine

DOI 10.1177/036354658301100602

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Abstract

Medial collateral ligament healing without treatment has been studied in a rabbit model. Complete midsubstance gaps were found to heal by distinct scar formation over time. This healing process was fast since the gap was bridged quickly; however, more subtle changes in ap pearance of the healing tissue continued for many months. The ligament "scar" was found to be structur ally abnormal chemically and mechanically even at long- term followup. A plateau in its improvement suggests that the scar may never approach normal ligament characteristics (without treatment). A baseline of liga ment healing by scar formation has been established.

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Authors: Frank, C., Woo, S. L.-Y., Amiel, D., Harwood, F., Gomez, M., & Akeson, W.
Affiliations: University of California San Diego (US)
United States Department of Veterans Affairs (US)
ORCID: Amiel, D.
Venue: The American Journal of Sports Medicine
Publisher: SAGE Publications
Published: 1983-11
Volume: 11
Issue: 6
Pages: 379-389
ISSN: 0363-5465 (ISSN-L)
1552-3365
DOI: 10.1177/036354658301100602
OpenAlex: W2052694074
Cited by: 367
References: 62
Citations by year: 2026: 3 · 2025: 1 · 2024: 2 · 2023: 6 · 2022: 4 · 2021: 7 · 2020: 5 · 2019: 10 · 2018: 11 · 2017: 9 · 2016: 8 · 2015: 5 · 2014: 8 · 2013: 16 · 2012: 8
FWCI: 5.04
Type: journal article
Language: en
Open access: closed
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: The American Journal of Sports Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Orthopedics and Sports Medicine › Tendon Structure and Treatment
Health Sciences › Medicine › Surgery › Knee injuries and reconstruction techniques
Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports injuries and prevention
Keywords: medial collateral ligament, ligament healing, scar formation, rabbit model, ligament biomechanics
MeSH terms: Animals, Biomechanical Phenomena, Body Water, Cicatrix, Collagen, DNA, Glycosaminoglycans, Knee Joint, Ligaments, Articular, Male, Rabbits, Wound Healing

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Medial collateral ligament healing: A multidisciplinary assessment in rabbits

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