Cited by 58Cancer survivorship and carePalliative and Oncologic CarePalliative Care and End-of-Life Issues

A comparison of psychosocial and physical functioning in patients with motor neurone disease and metastatic cancer

Clarke, David M., McLeod, Janet E., Smith, Graeme C., Trauer, Tom, Kissane, David W.·2005·Journal of Palliative Care

Abstract

Although their disease processes and treatments are different, patients with motor neurone disease (MND) and those with late-stage cancer share a common situation--one in which the quality of life, rather than a cure, becomes the focus of care. We report here a comparison of 126 patients with MND and 125 with metastatic cancer on a range of physical and psychosocial measures. Compared to cancer patients, MND patients were younger, had greater social contacts, but were more physically impaired. Cancer patients had more pain and were on more medication (opioids, steroids, and analgesics). Although the Beck depression scores were similar in both groups, MND patients had significantly higher scores for demoralization, hopelessness, and suicidal ideation. Cancer patients, on the other hand, scored significantly higher on anhedonia. We suggest this difference in the quality of depression represents a difference in illness experience of the two groups and has relevance for the ways we treat depression in the medically ill.

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Crossref · 10.1177/082585970502100310

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Authors
Clarke, D. M., McLeod, J. E., Smith, G. C., Trauer, T., & Kissane, D. W.
Affiliations
Monash Medical Centre (AU)
Venue
Journal of Palliative Care
Published
2005-09
Volume
21
Issue
3
Pages
173-179
ISSN
  • 0825-8597 (ISSN-L)
  • 2369-5293
OpenAlex
W2474962955
Cited by
58
References
40
Citations by year
2025: 1 · 2023: 3 · 2022: 2 · 2021: 3 · 2020: 1 · 2019: 5 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 4 · 2013: 17 · 2012: 3
FWCI
1.09
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Palliative Care (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Bethlehem Griffiths Research Foundation
  • Motor Neurone Disease Association
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
Keywords
motor neuron disease, metastatic cancer, psychosocial functioning, physical function, depression, quality of life, pain, demoralization, hopelessness, suicidal ideation, anhedonia, palliative care
MeSH terms
Activities of Daily Living, Adaptation, Psychological, Adolescent, Aged, Attitude to Health, Depression, Family, Female, Health Status, Humans, Interpersonal Relations, Middle Aged, Morale, Neoplasms, Pain, Palliative Care, Quality of Life, Surveys and Questionnaires, Social Support, Victoria, Logistic Models, Motor Neuron Disease

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