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Nonpharmacological Interventions to Improve Depression, Anxiety, and Quality of Life (QoL) in People With Dementia: An Overview of Systematic Reviews
Open accessAbstract
This overview aimed to systematically synthesize evidence from existing systematic reviews to signpost practitioners to the current evidence base on nonpharmacological interventions to improve depression, anxiety, and quality of life (QoL) in people with dementia and to discuss priorities for future research. The databases MEDLINE, PsycINFO, Scopus, and Cochrane Central Register of Controlled Trials were searched in August 2017 with an updated search in January 2019. Fourteen systematic reviews of randomized controlled trials of nonpharmacological interventions were identified. Dementia stage was rated moderate or severe in the majority of the reviews and type of dementia varied. Interventions reported to be effective were cognitive stimulation (QoL: standardized mean difference [SMD] = 0.38), music-based therapeutic interventions (depression: SMD = -0.27, anxiety: SMD = -0.43, QoL: SMD = 0.32), and psychological treatments (mainly cognitive behavior therapy; depression: SMD = -0.22, anxiety: MD = -4.57). Although health-care professionals are recommended to continue using these approaches, future research needs to focus on the type and form of interventions that are most effective for different stages and types of dementia.
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“Memantine can be used in conjunction with an AChEI because their modes of action are complimentary. The said combinatorial therapy is usually beneficial to patients, with cumulative results and no rise in side effects (Kishita et al., 2020).”
From An update on the novel and approved drugs for Alzheimer disease (2022) · cites this paper as Kishita et al., 2020
In the citing paper
“Memantine can be administered in combination with an AChEI, as they have complementary mechanisms of action.”
From Current and Future Treatments in Alzheimer Disease: An Update (2020) · cites this paper as [15]
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“Their combination benefits patients with usually additive effects, without any increase in adverse effects.14,15”
From Current and Future Treatments in Alzheimer Disease: An Update (2020) · cites this paper as [15]
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Kohne, Z. A. M., Ebadi, A., Farahani, M. A., Tajali, S., & Shahrestanaki, S. K. (2024) · BMJ Open Quality · doi:10.1136/bmjoq-2023-002673 · Cited by 3
“22 Based on the findings of this study and comparing them with previous studies, the QUALID Scale can be useful and applicable for assessing the QoL in elderly individuals with advanced stages of dementia.”
ResultHorticultural therapy impact on people with dementia
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“NPIs are gaining increased attention in research regarding their role in preventive and complementary care for the elderly, as demonstrated by several meta-analyses (Dyer et al., 2018; Frost et al., 2019; Kishita et al., 2020).”
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“Non-pharmacological therapy utilizes various factors such as open communication between healthcare provider and patient, behavioral therapy through consistency and simplifying the environment, cognitive-behavioral therapy, light therapy, and music therapy (2, 12, 13).”
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“An increasingly significant aspect in the exploration and management of cognitive impairment pertains to the subjective experience (Kishita, Backhouse and Mioshi, 2019; Kolanowski, Litaker and Catalano, 2002) and factors influencing variations in perceived quality of life levels (Goyal et al .,…”
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“Overall, dance and music therapy can be an enjoyable and effective way for older adults to improve their quality of life [5,7].”
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Metadata
- Authors
- Kishita, N., Backhouse, T., & Mioshi, E.
- Affiliations
- University of East Anglia (GB)
- Corresponding author
- Kishita, Naoko
- Venue
- Journal of Geriatric Psychiatry and Neurology
- Publisher
- SAGE Publications
- Published
- 2019-06-16
- Volume
- 33
- Issue
- 1
- Pages
- 28-41
- ISSN
- 0891-9887 (ISSN-L)
- 1552-5708
- OpenAlex
- W2952466078
- Cited by
- 103
- References
- 47
- Citations by year
- 2026: 3 · 2025: 11 · 2024: 21 · 2023: 26 · 2022: 16 · 2021: 13 · 2020: 11 · 2019: 1
- FWCI
- 1.73
- Type
- journal article
- Language
- en
- Open access
- green
- ueaeprints.uea.ac.uk
- Locations
- Journal of Geriatric Psychiatry and Neurology (publishedVersion)
- PubMed (publishedVersion)
- UEA Digital Repository (University of East Anglia) (acceptedVersion)
- Funders
- Alzheimer's Society
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Social Psychology › Music Therapy and Health
- Social Sciences › Psychology › Clinical Psychology › Art Therapy and Mental Health
- Keywords
- dementia, non-pharmacological treatment, depression, anxiety, quality of life, cognitive stimulation, music therapy, cognitive behavioral therapy, psychological intervention, dementia stages, dementia types
- MeSH terms
- Anxiety, Dementia, Depression, Humans, Quality of Life
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