Effects of mindfulness‐based interventions on reducing psychological distress among nurses: A systematic review and meta‐analysis of randomized controlled trials
Abstract
Purpose: Nurses increasingly use mindfulness as an effective mental health intervention to reduce psychological distress. The effectiveness of mindfulness‐based interventions remains inconclusive, which may lead to implementation of interventions in an inefficient or ineffective manner. This study aimed to examine the effects of mindfulness‐based interventions on reducing stress, anxiety, and depression among nurses. Design: Systematic review and meta‐analysis. Methods: Randomized controlled trials (RCTs) were searched using six databases published through May 20, 2023, which evaluated the effects of mindfulness‐based interventions on reducing psychological distress among nurses. To assess the quality of methodology included in the RCTs, version 2 of the Cochrane risk‐of‐bias instrument for RCTs with five domains was used. Standardized mean difference (SMD) with 95% confidence interval (CI) were calculated using the random–effects model in the meta‐analyses. Publication bias was assessed using Egger's regression test. Further, the robustness effect size of the pooled analysis was assessed using leave‐one‐out sensitivity analysis. Findings: A total of 16 RCTs were included in the final analysis. Overall, the modalities appeared to alleviate stress (pooled SMD: −0.50 [95% CI: −0.82 to −0.18]; p < 0.001) and depression (pooled SMD: −0.42 [95% CI: −0.78 to −0.06]; p = 0.02) among nurses. Conclusion: Mindfulness‐based interventions appear to alleviate stress and depression in nurses. Future research evaluating mindfulness‐based interventions among working nurses with more rigorous methodological and larger sample size. Clinical Relevance: Support for nurses' mental health must be included while implementing personal and professional development plans.
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Third-wave psychotherapies, including mindfulness-based interventions, compassion-based programs, and acceptance and commitment therapy, are effective in reducing occupational stress, anxiety, and depression while increasing resilience, including in health professionals.
“Different systematic reviews have underscored the effectiveness of third-wave psychotherapies, including mindfulness-based interventions, compassion-based programs, and acceptance and commitment therapy, in reducing occupational stress as well as anxiety and depression while increasing resilience, including in health professionals [18-21].”
Cites
The PRISMA 2020 statement: An updated guideline for reporting systematic reviews
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., Shamseer, L., Tetzlaff, J. M., Akl, E. A., Brennan, S. E., et al. (2021) · BMJ · doi:10.1136/bmj.n71 · Cited by 108,283 · see citing works
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139 · see citing works
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722 · see citing works
Cochrane Handbook for Systematic Reviews of Interventions
(2019) · doi:10.1002/9781119536604 · Cited by 14,828 · see citing works
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2021) · doi:10.1002/9781119558378 · Cited by 9,799 · see citing works
Mindfulness-based interventions in context: Past, present, and future
Kabat-Zinn, J. (2003) · Clinical Psychology: Science and Practice · doi:10.1093/clipsy.bpg016 · Cited by 8,615 · see citing works
Random-effects model for meta-analysis of clinical trials: An update
DerSimonian, R., & Kacker, R. (2007) · Contemporary Clinical Trials · doi:10.1016/j.cct.2006.04.004 · Cited by 2,374 · see citing works
Creswell, J. D. (2017) · Annual Review of Psychology · doi:10.1146/annurev-psych-042716-051139 · Cited by 1,702 · see citing works
Hariton, E., & Locascio, J. J. (2018) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.15199 · Cited by 1,604 · see citing works
Teasdale, J. D., Segal, Z., & Williams, J. M. G. (1995) · Behaviour Research and Therapy · doi:10.1016/0005-7967(94)e0011-7 · Cited by 1,349 · see citing works
Amir-Behghadami, M., & Janati, A. (2020) · Emergency Medicine Journal · doi:10.1136/emermed-2020-209567 · Cited by 1,335 · see citing works
Søvold, L. E., Naslund, J. A., Kousoulis, A. A., Saxena, S., Qoronfleh, M. W., Grobler, C., & Münter, L. (2021) · Frontiers in Public Health · doi:10.3389/fpubh.2021.679397 · Cited by 973 · see citing works
Mindfulness-based interventions: an overall review
Zhang, D., Lee, E. K. P., Mak, E. C. W., Ho, C. Y., & Wong, S. Y. S. (2021) · British Medical Bulletin · doi:10.1093/bmb/ldab005 · Cited by 668 · see citing works
Guendelman, S., Medeiros, S., & Rampes, H. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.00220 · Cited by 577 · see citing works
Nurses’ job stress and its impact on quality of life and caring behaviors: a cross-sectional study
Babapour, A.-R., Gahassab-Mozaffari, N., & Fathnezhad‐Kazemi, A. (2022) · BMC Nursing · doi:10.1186/s12912-022-00852-y · Cited by 465 · see citing works
Saragih, I. D., Tonapa, S. I., Saragih, I. S., Advani, S., Batubara, S. O., Suarilah, I., & Lin, C. (2021) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2021.104002 · Cited by 427 · see citing works
Self-citationKriakous, S. A., Elliott, K. A., Lamers, C., & Owen, R. (2021) · Mindfulness · doi:10.1007/s12671-020-01500-9 · Cited by 342 · see citing works
Nurses’ Adherence to Patient Safety Principles: A Systematic Review
Vaismoradi, M., Tella, S., Logan, P., Khakurel, J., & Vizcaya-Moreno, M. F. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17062028 · Cited by 336 · see citing works
Feasibility and Acceptability of a Resilience Training Program for Intensive Care Unit Nurses
Mealer, M. L., Conrad, D. L., Evans, J., Jooste, K., Solyntjes, J., ROTHBAUM, B. O., & Moss, M. (2014) · American Journal of Critical Care · doi:10.4037/ajcc2014747 · Cited by 319 · see citing works
Varghese, A., George, G., Kondaguli, S. V., Naser, A. Y., Khakha, D. C., & Chatterji, R. (2021) · Journal of Global Health · doi:10.7189/jogh.11.05009 · Cited by 234 · see citing works
Gartlehner, G., Wagner, G., Matyas, N., Titscher, V., Greimel, J., Lux, L., Gaynes, B. N., Viswanathan, M., Patel, S., & Lohr, K. N. (2017) · BMJ Open · doi:10.1136/bmjopen-2016-014912 · Cited by 192 · see citing works
Mindfulness-Based Interventions in Psychiatry
Shapero, B. G., Greenberg, J., Pedrelli, P., de Jong, M., & Desbordes, G. (2018) · Focus · doi:10.1176/appi.focus.20170039 · Cited by 172 · see citing works
Willis, B. H., & Riley, R. D. (2017) · Statistics in Medicine · doi:10.1002/sim.7372 · Cited by 171 · see citing works
School of Nursing, C. S. U., Yang, J., Tang, S., School of Nursing, C. S. U., Zhou, W., & The Second Xiangya Hospital, C. S. U. (2018) · Psychiatria Danubina · doi:10.24869/spsih.2018.189 · Cited by 163 · see citing works
A framework of nurses’ responsibilities for quality healthcare — Exploration of content validity
Oldland, E., Botti, M. A., Hutchinson, A. M., & Redley, B. (2019) · Collegian Journal of the Royal College of Nursing Australia · doi:10.1016/j.colegn.2019.07.007 · Cited by 147 · see citing works
Mindfulness in nursing: an evolutionary concept analysis
White, L. (2013) · Journal of Advanced Nursing · doi:10.1111/jan.12182 · Cited by 143 · see citing works
Mindfulness-based positive psychology interventions: a systematic review
George, A. J., Romate, J., & Rajkumar, E. (2021) · BMC Psychology · doi:10.1186/s40359-021-00618-2 · Cited by 143 · see citing works
The Community Resiliency Model® to promote nurse well-being
Grabbe, L., Higgins, M. K., Baird, M., Craven, P. A., & San Fratello, S. (2020) · Nursing Outlook · doi:10.1016/j.outlook.2019.11.002 · Cited by 136 · see citing works
Lin, L., He, G., Jin, Y., Gu, C., & Xie, J. (2018) · Workplace Health & Safety · doi:10.1177/2165079918801633 · Cited by 135 · see citing works
Outcomes of primary care delivery by nurse practitioners: Utilization, cost, and quality of care
Liu, C., Hebert, P. L., Douglas, J. H., Neely, E. L., Sulc, C. A., Reddy, A., Sales, A. E., & Wong, E. S. (2020) · Health Services Research · doi:10.1111/1475-6773.13246 · Cited by 121 · see citing works
Sulosaari, V., Ünal, E., & Çınar, F. İ. (2022) · Applied Nursing Research · doi:10.1016/j.apnr.2022.151565 · Cited by 119 · see citing works
Ramachandran, H. J., Bin Mahmud, M. S., Rajendran, P., Jiang, Y., Cheng, L., & Wang, W. (2023) · Journal of Clinical Nursing · doi:10.1111/jocn.16265 · Cited by 107 · see citing works
Enhancing resilience among new nurses: feasibility and efficacy of a pilot intervention.
(2015) · PubMed Central · Cited by 106 · see citing works
Kishita, N., Backhouse, T., & Mioshi, E. (2020) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988719856690 · Cited by 103 · see citing works
Taylor, H., Strauss, C., & Cavanagh, K. (2021) · Clinical Psychology Review · doi:10.1016/j.cpr.2021.102078 · Cited by 102 · see citing works
Zamanifar, S., Bagheri-Saweh, M. I., Nezakati, A., Mohammadi, R., & Seidi, J. (2020) · Journal of Medicine and Life · doi:10.25122/jml-2019-0105 · Cited by 95 · see citing works
Relaxation training methods for nurse managers in Hong Kong: a controlled study
Yung, P. M. B., Fung, M. Y., Chan, T. M. F., & Lau, B. W. K. (2004) · International Journal of Mental Health Nursing · doi:10.1111/j.1445-8330.2004.00342.x · Cited by 91 · see citing works
Huang, C. L.-C., Wu, M., Ho, C., & Wang, J.-J. (2018) · PLoS ONE · doi:10.1371/journal.pone.0204224 · Cited by 90 · see citing works
Ozgundondu, B., & Metin, Z. G. (2019) · Intensive and Critical Care Nursing · doi:10.1016/j.iccn.2019.07.007 · Cited by 86 · see citing works
Depression, Anxiety, Stress and Workplace Stressors among Nurses in Tertiary Health Care Settings
Kaushik, A., Ravikiran, S. R., Suprasanna, K., Nayak, M. G., Baliga, K., & Acharya, S. D. (2021) · Indian Journal of Occupational and Environmental Medicine · doi:10.4103/ijoem.ijoem_123_20 · Cited by 85 · see citing works
Yıldırım, D., & Yıldız, C. Ç. (2022) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000511 · Cited by 83 · see citing works
Lai, H.-L., & Li, Y.-M. (2011) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2011.05670.x · Cited by 82 · see citing works
Si̇s Çeli̇k, A., & Kılınç, T. (2022) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2022.101637 · Cited by 68 · see citing works
Croatto, G., Vancampfort, D., Miola, A., Olivola, M., Fiedorowicz, J. G., Firth, J., Alexinschi, O., Gaina, M. A., Makkai, V., Soares, F. C., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-022-01770-w · Cited by 66 · see citing works
Effectiveness of registered nurses on system outcomes in primary care: a systematic review
Lukewich, J., Asghari, S., Marshall, E. G., Mathews, M., Swab, M., Tranmer, J. E., Bryant‐Lukosius, D., Martin‐Misener, R., Norful, A. A., Ryan, D., et al. (2022) · BMC Health Services Research · doi:10.1186/s12913-022-07662-7 · Cited by 64 · see citing works
Watanabe, N., Horikoshi, M., Shinmei, I., Oe, Y., Narisawa, T., Kumachi, M., Matsuoka, Y., Hamazaki, K., & Furukawa, T. A. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.03.067 · Cited by 61 · see citing works
Playing music improves well-being of oncology nurses
Ploukou, S., & Panagopoulou, E. P. (2017) · Applied Nursing Research · doi:10.1016/j.apnr.2017.11.007 · Cited by 50 · see citing works
The effects of mindfulness‐based interventions on nurses' anxiety and depression: A meta‐analysis
Liu, H., Kong, L., Sun, Q., & Ma, X. (2023) · Nursing Open · doi:10.1002/nop2.1610 · Cited by 36 · see citing works
Maatouk, I., Müller, A., Angerer, P., Schmook, R., Nikendei, C., Herbst, K., Gantner, M., Herzog, W., & Gündel, H. (2018) · PLoS ONE · doi:10.1371/journal.pone.0191000 · Cited by 35 · see citing works
Kilpatrick, K., Nguemeleu, E. T., Fernández, N., Jabbour, M., Dubois, C., Paquette, L., Landry, V., Gauthier, N., & Beaulieu, M. (2021) · BMC Family Practice · doi:10.1186/s12875-021-01406-y · Cited by 34 · see citing works
Singh, S. K., & Gorey, K. M. (2018) · Social Work in Mental Health · doi:10.1080/15332985.2017.1373266 · Cited by 32 · see citing works
Ardıç, M., Ünal, Ö., & Türktemiz, H. (2022) · Journal of research in nursing · doi:10.1177/17449871211070982 · Cited by 31 · see citing works
Explanation of emotion regulation mechanism of mindfulness using a brain function model
Nakamura, H., Tawatsuji, Y., Fang, S., & Matsui, T. (2021) · Neural Networks · doi:10.1016/j.neunet.2021.01.029 · Cited by 29 · see citing works
Marsden, K. M., Porter, J. M., & Robertson, I. (2022) · PLoS ONE · doi:10.1371/journal.pone.0271824 · Cited by 28 · see citing works
Xiao, Y., Zhang, H., Li, Q., Xiao, S., Dai, T., Guo, J., & Yu, Y. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.812929 · Cited by 27 · see citing works
A Primary Care Nursing Perspective on Chronic Disease Prevention and Management
Griffin, C. D. (2017) · Delaware Journal of Public Health · doi:10.32481/djph.2017.03.011 · Cited by 26 · see citing works
Jung, S.-E., Ha, D.-J., Park, J.-H., Lee, B., Kim, M., Sim, K.-L., Choi, Y.-H., & Kwon, C.-Y. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18168855 · Cited by 23 · see citing works
Mealer, M. L., Boeldt, D. L., Cochran, K. L., Hodapp, R. M., Forster, J. E., Conrad, D., ROTHBAUM, B. O., Dimidjian, S., & Moss, M. M. (2021) · Open Journal of Nursing · doi:10.4236/ojn.2021.118055 · Cited by 19 · see citing works
Kang, M.-J., & Myung, S.-K. (2022) · Issues in Mental Health Nursing · doi:10.1080/01612840.2021.1949765 · Cited by 17 · see citing works
Mindfulness-based interventions to reduce stress and burnout in nurses: an integrative review
Armstrong, J. W., & Tume, L. N. (2022) · British Journal of Mental Health Nursing · doi:10.12968/bjmh.2020.0036 · Cited by 13 · see citing works
Online, low-volume meditation does not alter immune-related biomarkers
Graham, B., Jin, Y., Bazeley, P. S., Husni, M. E., & Calabrese, L. H. (2022) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2022.100531 · Cited by 12 · see citing works
Incorporating Mindfulness Practice for Better Performance in Work and Daily Life
Urcola‐Pardo, F. (2023) · Integrated science · doi:10.1007/978-3-031-15959-6_16 · Cited by 4 · see citing works
Marx, K., Duffort, N., Scerpella, D. L., Samus, Q. M., & Gitlin, L. N. (2017) · PubMed · Cited by 3 · see citing works
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López-del-Hoyo, Y., Fernández-Martínez, S., Perez-Aranda, A., Monreal-Bartolomé, A., Barceló-Soler, A., Camarero-Grados, L., Armas-Landaeta, C., Guzmán-Parra, J., Carbonell, V., Campos, D., et al. (2025) · Journal of Medical Internet Research · doi:10.2196/59653 · Cited by 9 · see citing works
- Authors
- Karo, M., Simorangkir, L., Daryanti Saragih, I., Suarilah, I., & Tzeng, H.
- Affiliations
- Sekolah Tinggi Ilmu Kesehatan Santa Elisabeth Medan (ID)
- College of Nursing, Kaohsiung Medical University Kaohsiung Taiwan
- Universitas Airlangga (ID)
- The University of Texas Medical Branch at Galveston (US)
- Venue
- Journal of Nursing Scholarship
- Publisher
- Wiley
- Published
- 2023-11-13
- Volume
- 56
- Issue
- 2
- Pages
- 319-330
- ISSN
- 0363-2792 (ISSN-L)
- 1527-6546
- 1547-5069
- OpenAlex
- W4388638593
- Cited by
- 20
- References
- 63
- Citations by year
- 2026: 11 · 2025: 8 · 2024: 1
- FWCI
- 1.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Nursing Scholarship (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Health Professions › Occupational Therapy › Occupational Health and Burnout
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Keywords
- mindfulness-based interventions, nurses, psychological distress, occupational stress, anxiety, depression, nurse mental health, workplace mental health interventions
- MeSH terms
- Psychological Distress, Anxiety, Depression, Humans, Nurses, Stress, Psychological, Randomized Controlled Trials as Topic, Mindfulness
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