Asymmetry in resting intracortical activity as a buffer to social threat
Open accessAbstract
Social rejection can create powerful changes in people's brains and bodies. In the study reported here, we examined brain-based individual differences associated with buffering against cardiovascular threat responses to social rejection. Using EEG source-localization techniques, we examined differences in intracortical asymmetry. We predicted that individuals with greater left relative to right dorsolateral prefrontal activity would show a more approach-motivated response to social rejection. Eighty-four female participants were randomly assigned to one of three stressful situations: social rejection, social evaluation without rejection, or self-evaluation. Among participants assigned to the social-rejection condition, greater left relative to right prefrontal intracortical activity at baseline was associated with more adaptive cardiovascular profiles and more self-reported approach-oriented emotions. Participants in the other conditions did not show these relationships. Our data are the first to show that social context matters when attempting to link individual differences in cortical asymmetry with approach-related cardiovascular and emotional outcomes.
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Individuals with higher left, relative to right, frontal cortical activity were more likely to respond to acute stress with challenge appraisals and challenge reactivity (higher CO and lower TPR).
“Specifically, individuals with higher left, relative to right, frontal cortical activity (a neurological pattern previously linked to positive affect and well-being) were more likely to respond to acute stress with challenge appraisals and challenge reactivity (higher CO and lower TPR; Koslov et al., 2011), suggesting a direct relationship between resting neurological activity and cardiovascular”
From More than a feeling: A unified view of stress measurement for population science (2018) · cites this paper as Koslov et al., 2011
The Results report that greater resting left frontal asymmetry predicted higher cardiac output and lower total peripheral resistance, but only during social-evaluative threat. The paper measured demand and resource appraisals, yet the passages do not show that left frontal asymmetry predicted more challenge appraisals; they report appraisal differences between experimental conditions instead. The claim also broadens a finding from social rejection in female participants to acute stress generally. (LLM, conf=0.86)
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Cites
Development and validation of brief measures of positive and negative affect: The PANAS scales.
Watson, D., Clark, L. A., & Tellegen, A. (1988) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.54.6.1063 · Cited by 32,433 · see citing works
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., et al. (2003) · Science · doi:10.1126/science.1083968 · Cited by 8,120 · see citing works
DeLamater, J., & Ward, A. (2013) · Handbooks of sociology and social research · doi:10.1007/978-94-007-6772-0 · Cited by 7,565 · see citing works
Dickerson, S. S., & Kemeny, M. E. (2004) · Psychological Bulletin · doi:10.1037/0033-2909.130.3.355 · Cited by 5,881 · see citing works
(2001) · doi:10.1017/cbo9780511546396 · Cited by 4,482 · see citing works
Does Rejection Hurt? An fMRI Study of Social Exclusion
Eisenberger, N. I., Lieberman, M. D., & Williams, K. D. (2003) · Science · doi:10.1126/science.1089134 · Cited by 3,849 · see citing works
Spherical splines for scalp potential and current density mapping
Perrin, F., Pernier, J., Bertrand, O., & Echallier, J. F. (1989) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(89)90180-6 · Cited by 2,706 · see citing works
Salivary cortisol in psychoneuroendocrine research: recent developments and applications
Kirschbaum, C., & Hellhammer, D. H. (1994) · Psychoneuroendocrinology · doi:10.1016/0306-4530(94)90013-2 · Cited by 2,107 · see citing works
Frontal EEG asymmetry as a moderator and mediator of emotion
Coan, J. A., & Allen, J. J. B. (2004) · Biological Psychology · doi:10.1016/j.biopsycho.2004.03.002 · Cited by 1,426 · see citing works
Petrides, M., & Pandya, D. N. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00518.x · Cited by 1,068 · see citing works
Arousal and physiological toughness: implications for mental and physical health
Dienstbier, R. A. (1989) · Psychological Review · doi:10.1037/0033-295x.96.1.84 · Cited by 909 · see citing works
The role of asymmetric frontal cortical activity in emotion-related phenomena: A review and update
Harmon‐Jones, E., Gable, P. A., & Peterson, C. K. (2009) · Biological Psychology · doi:10.1016/j.biopsycho.2009.08.010 · Cited by 881 · see citing works
Ostracism: the power of silence
(2002) · Choice Reviews Online · doi:10.5860/choice.39-4267 · Cited by 803 · see citing works
Harmon‐Jones, E., & Allen, J. J. B. (1998) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.74.5.1310 · Cited by 712 · see citing works
Pascual-Marqui, R. D., Lehmann, D., Koenig, T. W., Kochi, K., Merlo, M. C. G., Hell, D., & Koukkou, M. (1999) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(99)00013-x · Cited by 611 · see citing works
Making a Life Worth Living: Neural Correlates of Well-Being
Urry, H. L., Nitschke, J. B., Dolski, I., Jackson, D. C., Dalton, K. M., Mueller, C. J., Rosenkranz, M. A., Ryff, C. D., Singer, B. H., & Davidson, R. J. (2004) · Psychological Science · doi:10.1111/j.0956-7976.2004.00686.x · Cited by 576 · see citing works
Rajkowska, G., & Goldman, P. S. (1995) · Cerebral Cortex · doi:10.1093/cercor/5.4.323 · Cited by 562 · see citing works
Clarifying the emotive functions of asymmetrical frontal cortical activity
Harmon‐Jones, E. (2003) · Psychophysiology · doi:10.1111/1469-8986.00121 · Cited by 556 · see citing works
Davidson, R. J., Marshall, J. R., Tomarken, A. J., & Henriques, J. B. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00222-x · Cited by 432 · see citing works
Cacioppo, J. T., Hawkley, L. C., & Berntson, G. G. (2003) · Current Directions in Psychological Science · doi:10.1111/1467-8721.01232 · Cited by 397 · see citing works
Rajkowska, G., & Goldman, P. S. (1995) · Cerebral Cortex · doi:10.1093/cercor/5.4.307 · Cited by 392 · see citing works
Jackson, D. C., Mueller, C. J., Dolski, I., Dalton, K. M., Nitschke, J. B., Urry, H. L., Rosenkranz, M. A., Ryff, C. D., Singer, B. H., & Davidson, R. J. (2003) · Psychological Science · doi:10.1046/j.0956-7976.2003.psci_1473.x · Cited by 368 · see citing works
Mendes, W. B., Major, B., McCoy, S., & Blascovich, J. (2008) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.94.2.278 · Cited by 346 · see citing works
Self-citationCerebral asymmetry and emotion: Conceptual and methodological conundrums
Davidson, R. J. (1993) · Cognition & Emotion · doi:10.1080/02699939308409180 · Cited by 340 · see citing works
Functional but not structural subgenual prefrontal cortex abnormalities in melancholia
Pizzagalli, D. A., Oakes, T. R., Fox, A. S., Chung, M. K., Larson, C. L., Abercrombie, H. C., Schaefer, S. M., Benca, R. M., & Davidson, R. J. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001501 · Cited by 331 · see citing works
Self-citationFrontal Brain Asymmetry and Reward Responsiveness
Pizzagalli, D. A., Sherwood, R., Henriques, J. B., & Davidson, R. J. (2005) · Psychological Science · doi:10.1111/j.1467-9280.2005.01618.x · Cited by 326 · see citing works
Self-citationSocial psychophysiology and embodiment
Blascovich, J., & Mendes, W. B. (2010) · Handbook of Social Psychology · doi:10.1002/9780470561119.socpsy001006 · Cited by 274 · see citing works
Self-citationCardiac Index Is Associated With Brain Aging: The Framingham Heart Study
Jefferson, A. L., Himali, J. J., Beiser, A. S., Au, R., Massaro, J. M., Seshadri, S., Gona, P., Salton, C. J., DeCarli, C., O'Donnell, C. J., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.905091 · Cited by 256 · see citing works
Akinola, M., & Mendes, W. B. (2008) · Personality and Social Psychology Bulletin · doi:10.1177/0146167208323933 · Cited by 240 · see citing works
Self-citationFunctional coupling of simultaneous electrical and metabolic activity in the human brain
Oakes, T. R., Pizzagalli, D. A., Hendrick, A. M., Horras, K. A., Larson, C. L., Abercrombie, H. C., Schaefer, S. M., Koger, J. V., & Davidson, R. J. (2004) · Human Brain Mapping · doi:10.1002/hbm.20004 · Cited by 235 · see citing works
Self-citationPizzagalli, D. A., Nitschke, J. B., Oakes, T. R., Hendrick, A. M., Horras, K. A., Larson, C. L., Abercrombie, H. C., Schaefer, S. M., Koger, J. V., Benca, R. M., et al. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01313-6 · Cited by 209 · see citing works
Self-citationStroud, L. R., Tanofsky-Kraff, M., Wilfley, D. E., & Salovey, P. (2000) · Annals of Behavioral Medicine · doi:10.1007/bf02895115 · Cited by 184 · see citing works
Berkman, E. T., & Lieberman, M. D. (2009) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2009.21317 · Cited by 177 · see citing works
Decisions Under Distress: Stress Profiles Influence Anchoring and Adjustment
Kassam, K. S., Koslov, K., & Mendes, W. B. (2009) · Psychological Science · doi:10.1111/j.1467-9280.2009.02455.x · Cited by 175 · see citing works
Self-citationAyduk, Ö. N., Mischel, W., & Downey, G. (2002) · Psychological Science · doi:10.1111/1467-9280.00478 · Cited by 116 · see citing works
Symonds, C. S., Gallagher, P., Thompson, J., & Young, A. H. (2004) · Psychological Medicine · doi:10.1017/s0033291703008535 · Cited by 90 · see citing works
Lurito (2000) · doi:10.1002/1097-0193(200007)10:3
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Research works printed but not linked: 1
- First MB Spitzer RL Gibbon M Williams JBW Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version 2002 Biometrics Research, New York State Psychiatric Institute New York Patient Edition. (SCID-I/P)
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Epel, E. S., Crosswell, A. D., Mayer, S. E., Prather, A. A., Slavich, G. M., Puterman, E., & Mendes, W. B. (2018) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2018.03.001 · Cited by 1,077 · see citing works
“…to positive affect and well-being) were more likely to respond to acute stress with challenge appraisals and challenge reactivity (higher CO and lower TPR; Koslov et al., 2011), suggesting a direct relationship between resting neurological activity and cardiovascular reactivity during acute stress.”
BackgroundInfluentialSelf-citationMcLaughlin, K. A., Sheridan, M. A., Alves, S., & Mendes, W. B. (2014) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000098 · Cited by 149 · see citing works
Self-citationA heartfelt response: oxytocin effects on response to social stress in men and women
Kubzansky, L. D., Mendes, W. B., Appleton, A. A., Block, J., & Adler, G. K. (2012) · Biological Psychology · doi:10.1016/j.biopsycho.2012.02.010 · Cited by 142 · see citing works
Self-citationInteroception primes emotional processing: multimodal evidence from neurodegeneration
Salamone, P. C., Legaz, A., Sedeño, L., Moguilner, S., Fraile-Vazquez, M., Campo, C. G., Fittipaldi, S., Yoris, A., Miranda, M., Birba, A., et al. (2021) · The Journal of Neuroscience · doi:10.1523/jneurosci.2578-20.2021 · Cited by 103 · see citing works
EEG asymmetry in borderline personality disorder and depression following rejection.
Beeney, J. E., Levy, K. N., Gatzke-Kopp, L. M., & Hallquist, M. N. (2014) · Personality Disorders: Theory, Research, and Treatment · doi:10.1037/per0000032 · Cited by 93 · see citing works
Moyer, C. A., Donnelly, M. P. W., Anderson, J. C., Valek, K. C., Huckaby, S. J., Wiederholt, D. A., Doty, R. L., Rehlinger, A. S., & Rice, B. L. (2011) · Psychological Science · doi:10.1177/0956797611418985 · Cited by 56 · see citing works
- Authors
- Koslov, K., Mendes, W. B., Pajtas, P. E., & Pizzagalli, D. A.
- Affiliations
- University of California, San Francisco (US)
- Harvard University (US)
- Corresponding author
- Mendes, Wendy Berry
- Venue
- Psychological Science
- Publisher
- SAGE Publications
- Published
- 2011-04-05
- Volume
- 22
- Issue
- 5
- Pages
- 641-649
- ISSN
- 0956-7976 (ISSN-L)
- 1467-9280
- PMC
- PMC3196334
- OpenAlex
- W2105928505
- Cited by
- 80
- References
- 37
- Citations by year
- 2026: 2 · 2024: 2 · 2023: 6 · 2022: 5 · 2021: 7 · 2020: 4 · 2019: 3 · 2018: 7 · 2017: 8 · 2016: 9 · 2015: 4 · 2014: 12 · 2013: 4 · 2012: 5
- FWCI
- 3.74
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychological Science (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (HL079383, R01HL079383)
- National Institute of Mental Health (R01MH068376, MH68376)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hemispheric Asymmetry in Neuroscience
- Social Sciences › Psychology › Social Psychology › Death Anxiety and Social Exclusion
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- social rejection, dorsolateral prefrontal cortex, individual differences, approach motivation, social evaluation, self-assessment, EEG source localization
- MeSH terms
- Adult, Brain, Electroencephalography, Electrophysiology, Emotions, Female, Humans, Rejection, Psychology, Rest, Social Behavior, Prefrontal Cortex, Young Adult
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