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Cited by 272

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

The history of clozapine and its emergence in the US market: a review and analysis

Crilly, John·2007·History of Psychiatry
DOI 10.1177/0957154x07070335
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Abstract

Clozapine is known as the first `atypical' medication and is effective in people who have treatment-resistant schizophrenia. Its 1990 emergence in the USA was marked by considerable controversy over its high cost, due in large part to having been both the first new antipsychotic medication to come to market in over a decade and the need for comprehensive safety monitor ing within a decentralized health system. This paper traces the histor y of clozapine's discover y and development in Europe, its part in the 1975 Finnish agranulocytosis scare, and its subsequent volatile emergence in the USA. Analyses examine peripheral forces at the time, particularly the influence of political, corporate, medical and societal forces which shaped its market course.

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Metadata

Authors
Crilly, J.
Venue
History of Psychiatry
Publisher
SAGE Publications
Published
2007-03
Volume
18
Issue
1
Pages
39-60
ISSN
  • 0957-154X (ISSN-L)
  • 1740-2360
DOI
10.1177/0957154x07070335
OpenAlex
W1995063674
Cited by
272
References
28
FWCI
5.25
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The history of clozapine and its emergence in the US market: a review and analysis. https://app.cochat.ai/papers/10.1177/0957154x07070335
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Crilly, J. (2007). The history of clozapine and its emergence in the US market: a review and analysis. History of Psychiatry. https://doi.org/10.1177/0957154x07070335

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.