The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Traumatic Brain Injury: Current Treatment Strategies and Future Endeavors
Open accessAbstract
Traumatic brain injury (TBI) presents in various forms ranging from mild alterations of consciousness to an unrelenting comatose state and death. In the most severe form of TBI, the entirety of the brain is affected by a diffuse type of injury and swelling. Treatment modalities vary extensively based on the severity of the injury and range from daily cognitive therapy sessions to radical surgery such as bilateral decompressive craniectomies. Guidelines have been set forth regarding the optimal management of TBI, but they must be taken in context of the situation and cannot be used in every individual circumstance. In this review article, we have summarized the current status of treatment for TBI in both clinical practice and basic research. We have put forth a brief overview of the various subtypes of traumatic injuries, optimal medical management, and both the noninvasive and invasive monitoring modalities, in addition to the surgical interventions necessary in particular instances. We have overviewed the main achievements in searching for therapeutic strategies of TBI in basic science. We have also discussed the future direction for developing TBI treatment from an experimental perspective.
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“Given the potential risks associated with hypothermia and the mixed findings from previous studies, it is currently regarded as a second-line therapy for TBI [10,16,17].”
From Investigating the Safety and Efficacy of Therapeutic Hypothermia in Pediatric Severe Traumatic Brain Injury: A Systematic Review and Meta-Analysis (2024) · cites this paper as [17]
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Cites
Chronic traumatic encephalopathy in athletes: Progressive tauopathy after repetitive head injury
McKee, A. C., Cantu, R. C., Nowinski, C. J., Hedley-Whyte, E. T., Gavett, B. E., Budson, A. E., Santini, V. E., Lee, H.-S., Kubilus, C. A., & Stern, R. A. (2009) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3181a9d503 · Cited by 2,295
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Erythropoietin as an antiapoptotic, tissue-protective cytokine
Ghezzi, P., & Brines, M. (2004) · Cell Death & Differentiation · doi:10.1038/sj.cdd.4401450 · Cited by 327
Hall, E. D., Sullivan, P. G., Gibson, T. R., Pavel, K. M., Thompson, B. M., & Scheff, S. W. (2005) · Journal of Neurotrauma · doi:10.1089/neu.2005.22.252 · Cited by 319 · cited 1×
“The CCI model-induced brain injuries cause long-term neurobehavioral deficits that persist more than a year and are associated with cortical atrophy and reduced brain perfusion.(31,33)”
BackgroundXiong, Y., Mahmood, A., Meng, Y., Zhang, Y., Zhang, Z. G., Morris, D. C., & Chopp, M. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06683.x · Cited by 44
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Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders
Huang, Y., Liu, B., Sinha, S. C., Amin, S., & Gan, L. (2023) · Molecular Neurodegeneration · doi:10.1186/s13024-023-00672-x · Cited by 164
Role and therapeutic implications of protein glycosylation in neuroinflammation
Rebelo, A. L., Chevalier, M. T., Russo, L., & Pandit, A. (2022) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2022.01.004 · Cited by 50
Psychological Intervention in Traumatic Brain Injury Patients
Gómez-de-Regil, L., Estrella-Castillo, D. F., & Vega-Cauich, J. (2019) · Behavioural Neurology · doi:10.1155/2019/6937832 · Cited by 52
Extracellular vesicles as nanotheranostic platforms for targeted neurological disorder interventions
Choi, H. K., Chen, M., Goldston, L. L., & Lee, K.-B. (2024) · Nano Convergence · doi:10.1186/s40580-024-00426-5 · Cited by 26
Ghosh, S., & Ghosh, S. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.878058 · Cited by 13
Leonard, J., Wei, X., Browning, J., Gudenschwager-Basso, E. K., Li, J., Harris, E. A., Olsen, M. L., & Theus, M. H. (2024) · Scientific Reports · doi:10.1038/s41598-024-58904-z · Cited by 9
Kang, J., Zhou, Y., Xiong, Q., & Dong, X. (2024) · Aging · doi:10.18632/aging.205795 · Cited by 5
Naseri Alavi, S. A., Habibi, M. A., Majdi, A., Hajikarimloo, B., Rashidi, F., Fathi Tavani, S., Minaee, P., Eazi, S. M., & Kobets, A. J. (2024) · Children · doi:10.3390/children11060701 · Cited by 5
Metadata
- Authors
- Galgano, M., Toshkezi, G., Qiu, X., Russell, T., Chin, L., & Zhao, L.-R.
- Venue
- Cell Transplantation
- Publisher
- SAGE Publications
- Published
- 2017-06-30
- Volume
- 26
- Issue
- 7
- Pages
- 1118-1130
- ISSN
- 0963-6897 (ISSN-L)
- 1555-3892
- OpenAlex
- W2574652423
- Cited by
- 582
- References
- 5
- FWCI
- 14.48
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
