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The Teenage Brain: The Stress Response and the Adolescent Brain
Open accessAbstract
Adolescence is a time of many psychosocial and physiological changes. One such change is how an individual responds to stressors. Specifically, adolescence is marked by significant shifts in hypothalamic-pituitary-adrenal (HPA) axis reactivity, resulting in heightened stress-induced hormonal responses. It is presently unclear what mediates these changes in stress reactivity and what impacts they may have on an adolescent individual. However, stress-sensitive limbic and cortical brain areas that continue to mature during adolescence may be particularly vulnerable to these shifts in responsiveness. Consequently, perturbations of the maturing adolescent brain may contribute to the increase in stress-related psychological dysfunctions, such as anxiety, depression, and drug abuse, often observed during this stage of development. The purpose of this review is to describe the changes that occur in HPA function during adolescence, as well as to briefly discuss the possible ramifications of these changes on the developing brain and psychological health.
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“Adolescence also appears to be a period of development in which individuals are particularly sensitive to stressors (Broderick and Jennings 2012; Romeo 2013).”
From Mindfulness Interventions to Reduce Impact of Interparental Conflict on Adolescents. (2020) · cites this paper as Romeo 2013
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Metadata
- Authors
- Romeo, R. D.
- Affiliations
- Columbia University (US)
- Corresponding author
- Romeo, Russell D.
- ORCID
- Romeo, Russell D.
- Venue
- Current Directions in Psychological Science
- Publisher
- SAGE Publications
- Published
- 2013-04
- Volume
- 22
- Issue
- 2
- Pages
- 140-145
- ISSN
- 0963-7214 (ISSN-L)
- 1467-8721
- PMC
- PMC4274618
- OpenAlex
- W2103027336
- Cited by
- 343
- References
- 28
- Citations by year
- 2026: 43 · 2025: 29 · 2024: 35 · 2023: 39 · 2022: 39 · 2021: 43 · 2020: 23 · 2019: 19 · 2018: 26 · 2017: 11 · 2016: 15 · 2015: 11 · 2014: 7 · 2013: 3
- FWCI
- 5.47
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Current Directions in Psychological Science (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R03MH090224)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- adolescence, hypothalamic-pituitary-adrenal axis, stress reactivity, adolescent brain development, cortical maturation, anxiety, depression, drug abuse
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