Human cortical control of hand movements: Parietofrontal networks for reaching, grasping, and pointing
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In primates, control of the limb depends on many cortical areas. Whereas specialized parietofrontal circuits have been proposed for different movements in macaques, functional neuroimaging in humans has revealed widespread, overlapping activations for hand and eye movements and for movements such as reaching and grasping. This review examines the involvement of frontal and parietal areas in hand and arm movements in humans as revealed with functional neuroimaging. The degree of functional specialization, possible homologies with macaque cortical regions, and differences between frontal and posterior parietal areas are discussed, as well as a possible organization of hand movements with respect to different spatial reference frames. The available evidence supports a cortical organization along gradients of sensory (visual to somatosensory) and effector (eye to hand) preferences.
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Perceiving what is reachable activates motor representation of reaching actions, whose neural bases include motor and premotor regions (dorsal premotor cortex, supplementary motor area) and posterior parietal cortex (V6A and parietal reach region).
“Perceiving what is reachable indeed activates motor representation of reaching actions, whose neural bases are reported to include motor and premotor regions (the dorsal premotor cortex, the supplementary motor area), as well as posterior parietal cortex (V6A and parietal reach region in anterior and medial intraparietal sulcus)”
From The Peripersonal Space in a social world (2021) · cites this paper as Filimon, 2010
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Bédard, P., Thangavel, A., & Sanes, J. N. (2008) · Experimental Brain Research · doi:10.1007/s00221-008-1339-3 · Cited by 14 · see citing works
New Views of the Primary Motor Cortex
Schieber, M. H. (2000) · The Neuroscientist · doi:10.1177/107385840000600512 · Cited by 8 · see citing works
Matelli (1998) · doi:10.1002/(sici)1096-9861(19981221)402:3
Flagged first, then by citations
Research works printed but not linked: 2
- Blangero A, Menz MM, McNamara A, Binkofski F. 2009. Pari- etal modules for reaching. Neuropsychologia 47(6):1500-7.
- Soechting JF, Flanders M. 1998. Movement planning: kinemat- ics, dynamics, both or neither? In: Harris L, Jenkin M, edi- tors. Vision and action. New York: Cambridge University Press. p 352-71.
Cited by
Sorted by citations
The “What” and “When” of Self-Initiated Movements
Hoffstaedter, F., Grefkes, C., Zilles, K., & Eickhoff, S. B. (2013) · Cerebral Cortex · doi:10.1093/cercor/bhr391 · Cited by 166 · see citing works
Monaco, S., Cavina-Pratesi, C., Sedda, A., Fattori, P., Galletti, C., & Culham, J. C. (2011) · Journal of Neurophysiology · doi:10.1152/jn.01069.2010 · Cited by 104 · see citing works
The Peripersonal Space in a social world
Bogdanova, O. V., Bogdanov, V. B., Dureux, A., Farnè, A., & Hadj-Bouziane, F. (2021) · Cortex · doi:10.1016/j.cortex.2021.05.005 · Cited by 86 · see citing works
“in anterior and medial intraparietal sulcus) (Filimon, 2010; Lara et al., 2018; Monaco et al., 2011; Pitzalis et al., 2013).”
Background
- Authors
- Filimon, F.
- Affiliations
- Max Planck Institute for Human Development (DE)
- Corresponding author
- Filimon, Flavia
- Venue
- The Neuroscientist
- Publisher
- SAGE Publications
- Published
- 2010-08
- Volume
- 16
- Issue
- 4
- Pages
- 388-407
- ISSN
- 1073-8584 (ISSN-L)
- 1089-4098
- OpenAlex
- W2169124255
- Cited by
- 265
- References
- 105
- Citations by year
- 2026: 9 · 2025: 11 · 2024: 5 · 2023: 11 · 2022: 15 · 2021: 20 · 2020: 14 · 2019: 22 · 2018: 24 · 2017: 22 · 2016: 14 · 2015: 26 · 2014: 21 · 2013: 18 · 2012: 15
- FWCI
- 1.15
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- The Neuroscientist (publishedVersion)
- PubMed (publishedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- Max Planck Digital Library (submittedVersion)
- Funders
- Max-Planck-Gesellschaft
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Keywords
- hand movement, arm movement, reaching, grasping, pointing, frontal cortex, posterior parietal cortex, functional specialization, spatial reference frames, sensory preference, eye movements
- MeSH terms
- Animals, Brain Mapping, Eye Movements, Frontal Lobe, Hand, Humans, Macaca, Movement, Nerve Net, Neural Pathways, Parietal Lobe, Hand Strength
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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