Cited by 265Motor Control and AdaptationNeural and Behavioral Psychology StudiesAction Observation and Synchronization

Human cortical control of hand movements: Parietofrontal networks for reaching, grasping, and pointing

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Filimon, Flavia·2010·The Neuroscientist

Abstract

In primates, control of the limb depends on many cortical areas. Whereas specialized parietofrontal circuits have been proposed for different movements in macaques, functional neuroimaging in humans has revealed widespread, overlapping activations for hand and eye movements and for movements such as reaching and grasping. This review examines the involvement of frontal and parietal areas in hand and arm movements in humans as revealed with functional neuroimaging. The degree of functional specialization, possible homologies with macaque cortical regions, and differences between frontal and posterior parietal areas are discussed, as well as a possible organization of hand movements with respect to different spatial reference frames. The available evidence supports a cortical organization along gradients of sensory (visual to somatosensory) and effector (eye to hand) preferences.

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  • Perceiving what is reachable activates motor representation of reaching actions, whose neural bases include motor and premotor regions (dorsal premotor cortex, supplementary motor area) and posterior parietal cortex (V6A and parietal reach region).

    “Perceiving what is reachable indeed activates motor representation of reaching actions, whose neural bases are reported to include motor and premotor regions (the dorsal premotor cortex, the supplementary motor area), as well as posterior parietal cortex (V6A and parietal reach region in anterior and medial intraparietal sulcus)”

    From The Peripersonal Space in a social world (2021) · cites this paper as Filimon, 2010

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Research works printed but not linked: 2

  1. Blangero A, Menz MM, McNamara A, Binkofski F. 2009. Pari- etal modules for reaching. Neuropsychologia 47(6):1500-7.
  2. Soechting JF, Flanders M. 1998. Movement planning: kinemat- ics, dynamics, both or neither? In: Harris L, Jenkin M, edi- tors. Vision and action. New York: Cambridge University Press. p 352-71.

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Authors
Filimon, F.
Affiliations
Max Planck Institute for Human Development (DE)
Corresponding author
Filimon, Flavia
Venue
The Neuroscientist
Published
2010-08
Volume
16
Issue
4
Pages
388-407
ISSN
  • 1073-8584 (ISSN-L)
  • 1089-4098
OpenAlex
W2169124255
Cited by
265
References
105
Citations by year
2026: 9 · 2025: 11 · 2024: 5 · 2023: 11 · 2022: 15 · 2021: 20 · 2020: 14 · 2019: 22 · 2018: 24 · 2017: 22 · 2016: 14 · 2015: 26 · 2014: 21 · 2013: 18 · 2012: 15
FWCI
1.15
Type
journal article
Language
en
Open access
Locations
  • The Neuroscientist (publishedVersion)
  • PubMed (publishedVersion)
  • MPG.PuRe (Max Planck Society) (submittedVersion)
  • Max Planck Institute for Plasma Physics (submittedVersion)
  • Max Planck Digital Library (submittedVersion)
Funders
Max-Planck-Gesellschaft
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
Keywords
hand movement, arm movement, reaching, grasping, pointing, frontal cortex, posterior parietal cortex, functional specialization, spatial reference frames, sensory preference, eye movements
MeSH terms
Animals, Brain Mapping, Eye Movements, Frontal Lobe, Hand, Humans, Macaca, Movement, Nerve Net, Neural Pathways, Parietal Lobe, Hand Strength

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