Cited by 407Visual perception and processing mechanismsMotor Control and AdaptationSpatial Neglect and Hemispheric Dysfunction

Gaze-Centered Updating of Visual Space in Human Parietal Cortex

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Medendorp, W. Pieter, Goltz, Herbert C., Vilis, Tutis, Crawford, J. Douglas·2003·The Journal of Neuroscience

Abstract

Single-unit recordings have identified a region in the posterior parietal cortex (PPC) of the monkey that represents and updates visual space in a gaze-centered frame. Here, using event-related functional magnetic resonance imaging, we identified an analogous bilateral region in the human PPC that shows contralateral topography for memory-guided eye movements and arm movements. Furthermore, when eye movements reversed the remembered horizontal target location relative to the gaze fixation point, this PPC region exchanged activity across the two cortical lobules. This shows that the human PPC dynamically updates the spatial goals for action in a gaze-centered frame.

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Crossref · 10.1523/jneurosci.23-15-06209.2003

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  • A human homologue of monkey LIP has been identified by retinotopic mapping and implicated in gaze-centered updating of visual space, as well as in response to looming visuo-tactile stimuli.

    “A human homologous of monkey’s LIP has been identified by using retinotopic mapping and has been implicated in gaze-centered updating of visual space (Sereno et al. 2001; Medendorp et al. 2003), as well as in response to looming visuo-tactile stimuli (Huang et al. 2018).”

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Authors
Medendorp, W. P., Goltz, H. C., Vilis, T., & Crawford, J. D.
Affiliations
Western University (CA)
Venue
The Journal of Neuroscience
Published
2003-07-16
Volume
23
Issue
15
Pages
6209-6214
ISSN
  • 0270-6474 (ISSN-L)
  • 1529-2401
OpenAlex
W2124226813
Cited by
407
References
34
Citations by year
2026: 5 · 2025: 8 · 2024: 4 · 2023: 5 · 2022: 11 · 2021: 11 · 2020: 7 · 2019: 19 · 2018: 11 · 2017: 8 · 2016: 13 · 2015: 20 · 2014: 20 · 2013: 13 · 2012: 24
FWCI
11.40
Type
journal article
Language
en
Open access
Locations
  • Journal of Neuroscience (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Scholarship@Western (Western University) (submittedVersion, cc-by)
  • Radboud Repository (Radboud University) (submittedVersion)
  • Radboud Repository (Radboud University) (submittedVersion, other-oa)
Funders
Canadian Institutes of Health Research
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Spatial Neglect and Hemispheric Dysfunction
Keywords
posterior parietal cortex
MeSH terms
Adult, Arm, Brain Mapping, Fixation, Ocular, Humans, Magnetic Resonance Imaging, Male, Memory, Movement, Parietal Lobe, Photic Stimulation, Saccades, Space Perception, Visual Perception

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