Gaze-Centered Updating of Visual Space in Human Parietal Cortex
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Single-unit recordings have identified a region in the posterior parietal cortex (PPC) of the monkey that represents and updates visual space in a gaze-centered frame. Here, using event-related functional magnetic resonance imaging, we identified an analogous bilateral region in the human PPC that shows contralateral topography for memory-guided eye movements and arm movements. Furthermore, when eye movements reversed the remembered horizontal target location relative to the gaze fixation point, this PPC region exchanged activity across the two cortical lobules. This shows that the human PPC dynamically updates the spatial goals for action in a gaze-centered frame.
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A human homologue of monkey LIP has been identified by retinotopic mapping and implicated in gaze-centered updating of visual space, as well as in response to looming visuo-tactile stimuli.
“A human homologous of monkey’s LIP has been identified by using retinotopic mapping and has been implicated in gaze-centered updating of visual space (Sereno et al. 2001; Medendorp et al. 2003), as well as in response to looming visuo-tactile stimuli (Huang et al. 2018).”
From Neuroanatomical correlates of peripersonal space: bridging the gap between perception, action, emotion and social cognition (2024) · cites this paper as Medendorp et al. 2003
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Spatial updating and the maintenance of visual constancy
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Limb-Specific Representation for Reaching in the Posterior Parietal Cortex
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Spatial remapping of the visual world across saccades
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Remapping for visual stability
Hall, N. J., & Colby, C. L. (2011) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2010.0248 · Cited by 89 · see citing works
Behavioral Reference Frames for Planning Human Reaching Movements
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Self-citationBaker, J. T., Patel, G. H., Corbetta, M., & Snyder, L. H. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhi124 · Cited by 91 · see citing works
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Computations for geometrically accurate visually guided reaching in 3-D space.
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Self-citationIndependent on‐line control of the two hands during bimanual reaching
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Dissociating working memory updating and automatic updating: The reference-back paradigm.
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State estimation in posterior parietal cortex: Distinct poles of environmental and bodily states
Medendorp, W. P., & Heed, T. (2019) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2019.101691 · Cited by 84 · see citing works
Self-citationRight-hemispheric dominance for visual remapping in humans
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Reference Frames for Reach Planning in Human Parietofrontal Cortex
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Self-citationPrime, S. L., Vesia, M., & Crawford, J. D. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0542-08.2008 · Cited by 82 · see citing works
Self-citationCortical mechanisms for trans-saccadic memory and integration of multiple object features
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Self-citationRetinotopic memory is more precise than spatiotopic memory
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Visual memory capacity in transsaccadic integration
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Spatial constancy mechanisms in motor control
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Neuronal Synchronization in Human Posterior Parietal Cortex during Reach Planning
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Selective attention and the active remapping of object features in trans-saccadic perception
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Transsaccadic integration of visual features in a line intersection task
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Self-citationTopographic organization of macaque area LIP
Patel, G. H., Shulman, G. L., Baker, J. T., Akbudak, E., Snyder, A. Z., Snyder, L. H., & Corbetta, M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0908092107 · Cited by 71 · see citing works
Parietal stimulation destabilizes spatial updating across saccadic eye movements
Morris, A. P., Chambers, C., & Mattingley, J. B. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610508104 · Cited by 70 · see citing works
A visual processing but no phonological disorder in a child with mixed dyslexia
Valdois, S., Bidet-Ildei, C., Lassus‐Sangosse, D., Reilhac, C., Nguyen-Morel, M.-A., Guinet, É., & Orliaguet, J.-P. (2011) · Cortex · doi:10.1016/j.cortex.2011.05.011 · Cited by 72 · see citing works
Transient spatiotopic integration across saccadic eye movements mediates visual stability
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- Authors
- Medendorp, W. P., Goltz, H. C., Vilis, T., & Crawford, J. D.
- Affiliations
- Western University (CA)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2003-07-16
- Volume
- 23
- Issue
- 15
- Pages
- 6209-6214
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6740538
- OpenAlex
- W2124226813
- Cited by
- 407
- References
- 34
- Citations by year
- 2026: 5 · 2025: 8 · 2024: 4 · 2023: 5 · 2022: 11 · 2021: 11 · 2020: 7 · 2019: 19 · 2018: 11 · 2017: 8 · 2016: 13 · 2015: 20 · 2014: 20 · 2013: 13 · 2012: 24
- FWCI
- 11.40
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Neuroscience (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Scholarship@Western (Western University) (submittedVersion, cc-by)
- Radboud Repository (Radboud University) (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion, other-oa)
- Funders
- Canadian Institutes of Health Research
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Spatial Neglect and Hemispheric Dysfunction
- Keywords
- posterior parietal cortex
- MeSH terms
- Adult, Arm, Brain Mapping, Fixation, Ocular, Humans, Magnetic Resonance Imaging, Male, Memory, Movement, Parietal Lobe, Photic Stimulation, Saccades, Space Perception, Visual Perception
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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