Exercise Responses in Boys With Attention Deficit/Hyperactivity Disorder: Effects of Stimulant Medication
Abstract
Objective: The effect of stimulant medication on exercise responses was studied in 14 boys (10.9 ± 1.1 years) with attention deficit/hyperactivity disorder (ADHD). Method: Exercise, with and without medication, was performed at 25 W, 50 W, and 75 W, followed by a peak exercise test. Result: Submaximal heart rate (HR) was significantly higher by ~8 to 13 b·min —1 across the three intensities during the medication trial, but oxygen uptake (VO 2 ), respiratory exchange ratio (RER), and perceived exertion were similar ( p > .05). At peak exercise, VO 2 , HR, and work rate were attenuated ( p ≤ .05) in the absence of medication but not RER or perceived exertion. The decreased peak exercise responses were apparent in 6 of 13 participants. Conclusion: Stimulant medication raises submaximal HR but does not affect other cardiorespiratory measures or perceived exertion. Without medication physiological responses at peak exercise are attenuated in some but not all boys with ADHD. ( J. of Att. Dis. 2008; 12(2) 170-176)
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Common effects of stimulants on blood pressure, heart rate and exercise parameters are usually of no clinical significance.
“however, the common effects on blood pressure, heart rate and exercise parameters are usually of no clinical significance [55-57].”
From Advances in understanding and treating ADHD (2011) · cites this paper as [56]
Cites
Journal of Clinical Psychiatry
(2018) · Journal of Clinical Psychiatry · doi:10.5505/kpd · Cited by 13,703 · see citing works
Tanner, J. M. (1978) · Medical Entomology and Zoology · Cited by 3,742 · see citing works
Exercise Physiology: Energy, Nutrition, and Human Performance
McArdle, W. D., Katch, F. I., & Katch, V. L. (2006) · Cited by 2,633 · see citing works
Volkow, N. D., Wang, G.-J., Fowler, J. S., Gatley, S. J., Logan, J., Ding, Y.-S., Hitzemann, R., & Pappas, N. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.10.1325 · Cited by 885 · see citing works
Attention-deficit/hyperactivity disorder (adhd) as a noradrenergic disorder
Biederman, J., & Spencer, T. J. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00192-4 · Cited by 513 · see citing works
Altered reinforcement mechanisms in attention-deficit/hyperactivity disorder.
Sagvolden, T., Aase, H., Zeiner, P., & Berger, D. (1998) · PubMed · Cited by 491 · see citing works
Pediatric Sports Medicine for the Practitioner
Bar‐Or, O. (1983) · Comprehensive manuals in pediatrics · doi:10.1007/978-1-4612-5593-2 · Cited by 460 · see citing works
Assessment and Interpretation of Aerobic Fitness in Children and Adolescents
Armstrong, N., & Welsman, J. R. (1994) · Exercise and Sport Sciences Reviews · doi:10.1249/00003677-199401000-00016 · Cited by 408 · see citing works
Altered reinforcement mechanisms in attention-deficit/hyperactivity disorder
Sagvolden, T., Aase, H., Zeiner, P., & Berger, D. (1998) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)00170-8 · Cited by 345 · see citing works
The effects of exercise on children with attention-deficit hyperactivity disorder
Tantillo, M., Kesick, C. M., Hynd, G. W., & Dishman, R. K. (2002) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200202000-00004 · Cited by 154 · see citing works
Samuels, J., Franco, K., Wan, F., & Sorof, J. M. (2005) · Pediatric Nephrology · doi:10.1007/s00467-005-2051-1 · Cited by 138 · see citing works
Short-Term Cardiovascular Effects of Methylphenidate and Adderall
Findling, R. L., Short, E. J., & Manos, M. J. (2001) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200105000-00011 · Cited by 99 · see citing works
Catecholamine response to exercise in children with attention deficit hyperactivity disorder.
Wigal, S. B., Nemet, D., Swanson, J. M., Regino, R., Trampush, J., Ziegler, M. G., & Cooper, D. M. (2003) · Pediatric Research · doi:10.1203/01.pdr.0000061750.71168.23 · Cited by 92 · see citing works
Diagnosing attention-deficit/hyperactivity disorder in children.
Greenhill, L. L. (1998) · PubMed · Cited by 78 · see citing works
Cardiovascular Responses of Hyperactive Children to Methylphenidate
Ballard, J. E. (1976) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1976.03270260026021 · Cited by 72 · see citing works
Differentiated ratings of perceived exertion at ventilatory threshold in children and adults
Mahon, A. D., Gay, J. A., & Stolen, K. Q. (1998) · European Journal of Applied Physiology · doi:10.1007/s004210050395 · Cited by 67 · see citing works
Self-citationAttention Deficit/Hyperactivity Disorder
Sagvolden, T. (1999) · European Psychologist · doi:10.1027//1016-9040.4.2.109 · Cited by 43 · see citing works
Brown, R. T., & Sexson, S. B. (1989) · Journal of Adolescent Health Care · doi:10.1016/0197-0070(89)90229-5 · Cited by 40 · see citing works
Attention Deficit Hyperactivity Disorder, CNS Stimulants and Sport
Hickey, G. J., & Fricker, P. A. (1999) · Sports Medicine · doi:10.2165/00007256-199927010-00002 · Cited by 34 · see citing works
Butte, N. F., Treuth, M. S., Voigt, R. G., Llorente, A. M., & Heird, W. C. (1999) · The Journal of Pediatrics · doi:10.1016/s0022-3476(99)70023-5 · Cited by 33 · see citing works
Blunted Catecholamine Responses after Glucose Ingestion in Children with Attention Deficit Disorder
Girardi, N. L., Shaywitz, S. E., Shaywitz, B. A., Marchione, K. E., Fleischman, S. J., Jones, T. W., & Tamborlane, W. V. (1995) · Pediatric Research · doi:10.1203/00006450-199510000-00011 · Cited by 29 · see citing works
Methylphenidate in Children: Effects upon Cardiorespiratory Function on Exertion
Aman, M. G., & WERRY, J. S. (1975) · International Journal of Mental Health · doi:10.1080/00207411.1975.11448678 · Cited by 18 · see citing works
Effect of Methylphenidate on Cardiorespiratory Responses in Hyperactive Children
Boileau, R. A., Ballard, J. E., Sprague, R. L., Sleator, E. K., & Massey, B. H. (1976) · Research Quarterly for Exercise and Sport · doi:10.1080/10671315.1976.10616715 · Cited by 16 · see citing works
Mahon, A. D., Plank, D. M., & Hipp, M. J. (2003) · Canadian Journal of Applied Physiology · doi:10.1139/h03-005 · Cited by 5 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Advances in understanding and treating ADHD
Antshel, K. M., Hargrave, T. M., Simonescu, M., Kaul, P., Hendricks, K., & Faraone, S. V. (2011) · BMC Medicine · doi:10.1186/1741-7015-9-72 · Cited by 140 · see citing works
Diurnal variations in arousal: a naturalistic heart rate study in children with ADHD
Imeraj, L., Antrop, I., Roeyers, H., Deschepper, E., Bal, S., & Deboutte, D. (2011) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-011-0188-y · Cited by 52 · see citing works
- Authors
- Mahon, A. D., Stephens, B. R., & Cole, A. S.
- Affiliations
- Ball State University (US)
- ORCID
- Mahon, Anthony D.
- Venue
- Journal of Attention Disorders
- Publisher
- SAGE Publications
- Published
- 2007-10-12
- Volume
- 12
- Issue
- 2
- Pages
- 170-176
- ISSN
- 1087-0547 (ISSN-L)
- 1557-1246
- OpenAlex
- W2085236410
- Cited by
- 24
- References
- 24
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2014: 1 · 2013: 1 · 2012: 4
- FWCI
- 0.40
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Attention Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Keywords
- attention deficit hyperactivity disorder, stimulant medication, exercise response, cardiorespiratory responses, heart rate, oxygen consumption, respiratory exchange ratio, perceived exertion, peak exercise, boys, exercise intensity
- MeSH terms
- Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Child, Heart Rate, Humans, Male, Methylphenidate, Severity of Illness Index, Time Factors, Exercise, Treatment Outcome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
