Kynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects

Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism

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An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

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An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

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Relationship between interferon‐γ, indoleamine 2,3‐dioxygenase, and tryptophan catabolism

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Neuropharmacology of quinolinic and kynurenic acids.

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Role of Poly(ADP-ribose) Polymerase (PARP) Cleavage in Apoptosis

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Tryptophan and the immune response

Moffett, J., & Namboodiri, M. (2003) · Immunology and Cell Biology · doi:10.1046/j.1440-1711.2003.t01-1-01177.x · Cited by 765

Zinc, Insulin and Diabetes

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Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion

Platten, M., Wick, W., & den Eynde, B. J. V. (2012) · Cancer Research · doi:10.1158/0008-5472.can-12-0569 · Cited by 725

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

Nguyen, N. T., Kimura, A., Nakahama, T., Chinen, I., Masuda, K., Nohara, K., Fujii‐Kuriyama, Y., & Kishimoto, T. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1014465107 · Cited by 705

Circadian control of kynurenine pathway enzymes in the rat pineal gland, liver, and heart and tissue- and enzyme-specific responses to lipopolysaccharide

Moravcová, S., Spišská, V., Pačesová, D., Hrubcová, L., Kubištová, A., Novotný, J., & Bendová, Z. (2022) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2022.109213 · Cited by 14

Blood Biomarkers of Response to Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer

Lage, Y., Olmedo, M. E., Rueda, A. G., Ballesteros, P. Á., Rodríguez, D. R., & Velasco, M. T. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11113245 · Cited by 15

Identification of l ‐Tryptophan by down‐field 1H MRS: A precursor for brain NAD+ and serotonin syntheses

Nanga, R. P. R., Elliott, M. A., Swain, A., Wilson, N. E., Swago, S., Soni, N. D., Witschey, W. R. T., & Reddy, R. D. (2022) · Magnetic Resonance in Medicine · doi:10.1002/mrm.29414 · Cited by 14

The effect of inflammation, SARS-CoV-2 infection, age and mental health on serotonin, and kynurenine and catecholamine pathway metabolites

Hüfner, K., Vedova, S., Tymoszuk, P., Nelles, P., Bruckner, T., Deisenhammer, E., Egeter, J., Gálffy, M., Giesinger, J. M., Lehmann, J., et al. (2023) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2023.106334 · Cited by 14

Urinary Excretion of N1-methyl-2-pyridone-5-carboxamide and N1-methylnicotinamide in Renal Transplant Recipients and Donors

Deen, C. P. J., van der Veen, A., Neto, A. W. G., Geleijnse, J. M., den Berg, K. J. B., Heiner-Fokkema, M. R., Kema, I. P., & Bakker, S. J. L. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9020437 · Cited by 14

The Microbiome and Metabolic Dysfunction-Associated Steatotic Liver Disease

Beyoğlu, D., & Idle, J. R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26072882 · Cited by 15

Kynurenine promotes the immune escape of colorectal cancer cells via NAT10-mediated ac4C acetylation of PD-L1

Wang, Z., Yin, M., Zhou, R., Li, M., Peng, J., & Wang, Z. (2025) · Clinics · doi:10.1016/j.clinsp.2025.100658 · Cited by 13

Mechanisms of the effect of gut microbes on depression through the microbiota-gut-brain axis

Zhou, X., Wang, S., Wang, X., Chen, X., Zhou, P., Ma, K., & Zhang, P. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1634548 · Cited by 14

A Vegetarian Diet Significantly Changes Plasma Kynurenine Concentrations

Bjørke‐Monsen, A., Varsi, K., Ulvik, A., Sakkestad, S. T., & Ueland, P. M. (2023) · Biomolecules · doi:10.3390/biom13020391 · Cited by 13

Prominent Targets for Cancer Care: Immunotherapy Perspective

Patel, M. M., Thakkar, A., Bhatt, P. R., Shah, U., Patel, A. D., Solanki, N. D., Patel, S., Patel, S., Gandhi, K., & Patel, B. A. (2023) · Current Cancer Therapy Reviews · doi:10.2174/1573394719666230306121408 · Cited by 13

Lipopolysaccharide-induced changes in the kynurenine pathway and symptoms of sickness behavior in humans

Balter, L. J. T., Li, X., Schwieler, L., Erhardt, S., Axelsson, J., Olsson, M. J., Lasselin, J., & Lekander, M. (2023) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2023.106110 · Cited by 13

Pathological shifts in tryptophan metabolism in human term placenta exposed to LPS or poly I:C

Abad, C., Karahoda, R., Orbisova, A., Kastner, P., Heblik, D., Kučera, R., Portillo, R., & Štaud, F. (2023) · Biology of Reproduction · doi:10.1093/biolre/ioad181 · Cited by 14

Small Phenolic Metabolites at the Nexus of Nutrient Transport and Energy Metabolism

Mhawish, R., & Komarnytsky, S. (2025) · Molecules · doi:10.3390/molecules30051026 · Cited by 13

Unraveling the molecular mechanisms of vitamin deficiency in Alzheimer's disease pathophysiology

Sharma, V., & Aran, K. R. (2025) · Aging and Health Research · doi:10.1016/j.ahr.2025.100226 · Cited by 13

Maternally Inherited Differences within Mitochondrial Complex I Control Murine Healthspan

Hirose, M., Schilf, P., Zarse, K., Busch, H. S., Fuellen, G., Jöhren, O., Köhling, R., König, I. R., Richer, B. C., Rupp, J., et al. (2019) · Genes · doi:10.3390/genes10070532 · Cited by 13

The effect of obstructive sleep apnea on peripheral blood amino acid and biogenic amine metabolome at multiple time points overnight

Kiens, O., Taalberg, E., Ivanova, V., Veeväli, K., Laurits, T., Tamm, R., Ottas, A., Kilk, K., Soomets, U., & Altraja, A. (2021) · Scientific Reports · doi:10.1038/s41598-021-88409-y · Cited by 13

Effect of a Single Bout of Aerobic Exercise on Kynurenine Pathway Metabolites and Inflammatory Markers in Prostate Cancer Patients—A Pilot Randomized Controlled Trial

Schenk, A., Esser, T., Knoop, A., Thevis, M., Herden, J., Heidenreich, A., Bloch, W., Joisten, N., & Zimmer, P. (2020) · Metabolites · doi:10.3390/metabo11010004 · Cited by 13

Elevated serum levels of kynurenine pathway metabolites in patients with Behçet disease

Onmaz, D. E., Tezcan, D., Abuşoğlu, S., Sivrikaya, A., Kuzu, M., Yerlikaya, F. H., Yi̇lmaz, S., & Ünlü, A. (2022) · Amino Acids · doi:10.1007/s00726-022-03170-4 · Cited by 13

Beta-Glucan Alters Gut Microbiota and Plasma Metabolites in Pre-Weaning Dairy Calves

Luo, Z., Ma, L., Zhou, T., Huang, Y., Zhang, L., Du, Z., Yong, K., Yao, X., Shen, L., Yu, S., et al. (2022) · Metabolites · doi:10.3390/metabo12080687 · Cited by 13

The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis

Liu, Z. F., Sylivris, A., Gordon, M., & Sundram, S. (2022) · BMC Psychiatry · doi:10.1186/s12888-022-04178-6 · Cited by 13

Dietary Fish Meal Level and a Package of Choline, β-Glucan, and Nucleotides Modulate Gut Function, Microbiota, and Health in Atlantic Salmon (Salmo salar, L.)

Krogdahl, Å., Chikwati, E., Krasnov, A., Dhanasiri, A. K. S., Berge, G. M., Aru, V., Khakimov, B., Engelsen, S. B., Vinje, H., & Kortner, T. M. (2023) · Aquaculture Nutrition · doi:10.1155/2023/5422035 · Cited by 16

Genome sequence of the fungus Pycnoporus sanguineus, which produces cinnabarinic acid and pH- and thermo- stable laccases

Lin, W., Jia, G., Sun, H., Sun, T., & Hou, D. (2020) · Gene · doi:10.1016/j.gene.2020.144586 · Cited by 13

Kynurenine Pathway in Epilepsy: Unraveling Its Role in Glutamate Excitotoxicity, GABAergic Dysregulation, Neuroinflammation, and Mitochondrial Dysfunction

Kaur, M., Porel, P., Patel, R., & Aran, K. R. (2025) · Neurotoxicity Research · doi:10.1007/s12640-025-00738-2 · Cited by 12

Preliminary Evidence of Endotoxin Tolerance in Dairy Cows during the Transition Period

Filipe, J., Inglesi, A., Amadori, M., Guarneri, F., Menchetti, L., Curone, G., Brecchia, G., Vigo, D., & Riva, F. (2021) · Genes · doi:10.3390/genes12111801 · Cited by 12

Stress and Kynurenine-Inflammation Pathway in Major Depressive Disorder

Mingoti, M. E. D., Bertollo, A. G., de Oliveira, T., & Ignácio, Z. M. (2023) · Advances in experimental medicine and biology · doi:10.1007/978-981-19-7376-5_8 · Cited by 12

Chronic infusion of the tryptophan metabolite kynurenine increases mean arterial pressure in male Sprague-Dawley rats

Irsik, D. L., Chen, J., Bollag, W. B., & Isales, C. M. (2024) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00019.2024 · Cited by 12

Sirtuin 1 regulates the phenotype and functions of dendritic cells through Ido1 pathway in obesity

de Lima, J., Leite, J. A., Basso, P. J., Ghirotto, B., da Silva, E. M., Menezes-Silva, L., Hiyane, M. I., Goes, C. P., Coutinho, L. L., Andrade‐Oliveira, V., et al. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-07125-3 · Cited by 13

The Fate of Dietary Tryptophan in Fish: Unveiling Its Sources, Transport, Metabolism, and Multifaceted Impacts

Kalaiselvan, P., Ranjan, A., Thangarani, A. J., Felix, N., & Akamad, D. K. (2025) · Journal of Nutrition · doi:10.1016/j.tjnut.2025.05.034 · Cited by 12

Clinicopathologic features of TDO2 overexpression in renal cell carcinoma

Phạm, Q. T., Taniyama, D., Sekino, Y., Akabane, S., Babasaki, T., Kobayashi, G., Sakamoto, N., Sentani, K., Oue, N., & Yasui, W. (2021) · BMC Cancer · doi:10.1186/s12885-021-08477-1 · Cited by 12

Caffeine protects against stress-induced murine depression through activation of PPARγC1α-mediated restoration of the kynurenine pathway in the skeletal muscle

Fang, C., Hayashi, S., Du, X., Cai, X., Deng, B., Zheng, H., Ishido, S., Tsutsui, H., & Sheng, J. (2021) · Scientific Reports · doi:10.1038/s41598-021-86659-4 · Cited by 12

Neonatal encephalopathy plasma metabolites are associated with neurodevelopmental outcomes

Friedes, B. D., Molloy, E. J., Strickland, T., Zhu, J., Slevin, M., Donoghue, V. B., Sweetman, D., Kelly, L. A., O’Dea, M. I., Roux, A., et al. (2021) · Pediatric Research · doi:10.1038/s41390-021-01741-x · Cited by 12

Vitamin B3 (niacin), B6, C, and iron intake are associated with the free androgen index, especially in normoandrogenic polycystic ovary syndrome

Brilliant, A., Astuti, B. P. K., Joyo, E. O., Febri, R. R., Silvana, V., & Muharam, R. (2022) · Journal of the Turkish-German Gynecological Association · doi:10.4274/jtgga.galenos.2022.2022-2-1 · Cited by 12

Modulation of immune cell function, IDO expression and kynurenine production by the quorum sensor 2-heptyl-3-hydroxy-4-quinolone (PQS)

Ogbechi, J., Huang, Y., Clanchy, F. I. L., Pantazi, E. D., Topping, L. M., Darlington, L. G., Williams, R. O., & Stone, T. W. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1001956 · Cited by 12

SLC6A4 DNA Methylation Levels and Serum Kynurenine/Tryptophan Ratio in Eating Disorders: A Possible Link with Psychopathological Traits?

Franzago, M., Orecchini, E., Porreca, A., Mondanelli, G., Orabona, C., Ragione, L. D., Nicola, M. D., Stuppia, L., Vitacolonna, E., Beccari, T., et al. (2023) · Nutrients · doi:10.3390/nu15020406 · Cited by 14

Impaired kynurenine metabolism in patients with primary Sjögren’s syndrome

Onmaz, D. E., Tezcan, D., Abuşoğlu, S., Sak, F., Yerlikaya, F. H., Yi̇lmaz, S., Abuşoğlu, G., Körez, M. K., & Ünlü, A. (2023) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2023.01.007 · Cited by 12

Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans

U-Din, M., de Mello, V. D., Tuomainen, M. H., Raiko, J. R. H., Niemi, T. S., Fromme, T., Klåvus, A., Gautier, N., Haimilahti, K., Lehtonen, M., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.113131 · Cited by 17

New Approaches to Fetal Growth Restriction: The Time for Metabolomics Has Come

Leite, D. F. B., & Cecatti, J. G. (2019) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1055/s-0039-1692126 · Cited by 12

Exercise-driven changes in tryptophan metabolism leading to healthy aging

Asante, D. M., Vyavahare, S. S., Shukla, M., McGee‐Lawrence, M. E., Isales, C. M., & Fulzele, S. (2025) · Biochimie · doi:10.1016/j.biochi.2025.11.004 · Cited by 11

The role of gut dysbiosis and mitochondrial dysfunction in type 2 diabetes: Insights on pathogenesis, intervention and future perspective

Yu, X., Li, M., & Li, H. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118846 · Cited by 13

Chronic Inflammatory Enteropathy and Low-Grade Intestinal T-Cell Lymphoma Are Associated with Altered Microbial Tryptophan Catabolism in Cats

Barko, P. C., Williams, D. A., Wu, Y., Steiner, J. M., Suchodolski, J. S., Gal, A., & Marsilio, S. (2023) · Animals · doi:10.3390/ani14010067 · Cited by 11

Micronutrient status in children aged 6–59 months with severe wasting and/or nutritional edema: implications for nutritional rehabilitation formulations

Vresk, L., Flanagan, M., Daniel, A. I., Potani, I., Bourdon, C., Spiegel-Feld, C., Thind, M. K., Farooqui, A., Ling, C., Miraglia, E., et al. (2023) · Nutrition Reviews · doi:10.1093/nutrit/nuad165 · Cited by 12

Sex-specific associations of kynurenic acid with neopterin in Alzheimer’s disease

Knapskog, A., Edwin, T. H., Ueland, P. M., Ulvik, A., Fang, E. F., Eldholm, R. S., Halaas, N. B., Giil, L. M., Saltvedt, I. T., Watne, L. O., et al. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01531-7 · Cited by 11

The role of aryl hydrocarbon receptor in antiviral immunity: a focus on RNA viruses

Grycová, A., Vyhlídalová, B., & Dvořák, Z. (2025) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2025.2497789 · Cited by 11

Aging immunity: unraveling the complex nexus of diet, gut microbiome, and immune function

Babakhani, K., Kucinskas, A. L., Ye, X., Giles, E. D., & Sun, Y. (2025) · Immunometabolism · doi:10.1097/in9.0000000000000061 · Cited by 12

Design, synthesis and biological evaluation of bicyclic carboxylic acid derivatives as IDO1 inhibitors

Cai, S., Yang, X., Chen, P., Liu, X., Zhou, J., & Zhang, H. (2019) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2019.103356 · Cited by 11

Twists and Turns in the Salicylate Catabolism of Aspergillus terreus , Revealing New Roles of the 3-Hydroxyanthranilate Pathway

Martins, T. M., Martins, C., Guedes, P. R., & Pereira, C. S. (2021) · mSystems · doi:10.1128/msystems.00230-20 · Cited by 11

Role of maternal tryptophan metabolism in allergic diseases in the offspring

Lau, H. X., El‐Heis, S., Yap, Q. V., Chan, Y. H., Tan, C. P. T., Karnani, N., Tan, K. M. L., Tham, E. H., Goh, A. E. N., Teoh, O. H., et al. (2021) · Clinical & Experimental Allergy · doi:10.1111/cea.13953 · Cited by 11

IL4I1 and tryptophan metabolites enhance AHR signals to facilitate colorectal cancer progression and immunosuppression.

Sun, H., Han, W., Wen, J., & Ma, X. (2022) · PubMed Central · Cited by 11

Untargeted metabolomic profiling of sepsis-induced cardiac dysfunction

Cao, Y., Liu, Z., Ma, W., Chen, F., Pei, Y., Jing, Y., Huang, J., Han, X., & Xiao, W. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1060470 · Cited by 12

Discovery and biological evaluation of a new type of dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase from ethnomedicinal plant Dactylicapnos scandens

Bao, M., Yang, X., Wu, J., Liu, J., & Cai, X. (2023) · Phytochemistry · doi:10.1016/j.phytochem.2023.113794 · Cited by 11

The plasma kynurenine-to-tryptophan ratio as a biomarker of tuberculosis disease in people living with HIV on antiretroviral therapy: an exploratory nested case–control study

Gatechompol, S., Lutter, R., Vaz, F. M., Ubolyam, S., Avihingsanon, A., Kerr, S. J., van Leth, F., & Cobelens, F. G. J. (2024) · BMC Infectious Diseases · doi:10.1186/s12879-024-09258-4 · Cited by 11

Risk of Fat Mass- and Obesity-Associated Gene-Dependent Obesogenic Programming by Formula Feeding Compared to Breastfeeding

Melnik, B. C., Weiskirchen, R., Stremmel, W., John, S. M., & Schmitz, G. (2024) · Nutrients · doi:10.3390/nu16152451 · Cited by 11

Analysis of Tryptophan Metabolites in Serum Using Wide-Isolation Strategies for UHPLC–HRMS/MS

Rubio, V. Y., Cagmat, J. G., Wang, G. P., Yost, R. A., & Garrett, T. J. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.9b04210 · Cited by 12

Kynurenine pathway of tryptophan metabolism in patients with familial Mediterranean fever

Tezcan, D., Onmaz, D. E., Sivrikaya, A., Körez, M. K., Hakbilen, S., Gülcemal, S., & Yi̇lmaz, S. (2022) · Modern Rheumatology · doi:10.1093/mr/roac016 · Cited by 11

Kynurenine/tryptophan ratio for detection of active tuberculosis in adults with HIV prior to antiretroviral therapy

Olsson, O., Skogmar, S., Tesfaye, F., Mulleta, D., Jansson, M., & Björkman, P. (2022) · AIDS · doi:10.1097/qad.0000000000003235 · Cited by 11

Co-Expression Network and Integrative Analysis of Metabolome and Transcriptome Uncovers Biological Pathways for Fertility in Beef Heifers

Banerjee, P., Rodning, S. P. P., Diniz, W. J. S., & Dyce, P. W. (2022) · Metabolites · doi:10.3390/metabo12080708 · Cited by 11

Role of the kynurenine pathway and the endocannabinoid system as modulators of inflammation and personality traits

Heilman, P. L., Hill, M. N., Coussons‐Read, M. E., Brundin, L., & Coccaro, E. F. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.104434 · Cited by 11

Investigation of the effects of oxidative stress, inflammation on the pathway of tryptophan/kynurenine in OCD

Delen, E., Küçükali, C. İ., Karaaslan, Z., Yüceer, H., Punar, S., Hakan, M. T., Yaylım, İ., & Özkök, E. (2023) · Acta Neuropsychiatrica · doi:10.1017/neu.2023.55 · Cited by 11

Inflammation, the kynurenines, and mucosal injury during human experimental enterotoxigenic Escherichia coli infection

Rim, S., Vedøy, O. B., Brønstad, I., McCann, A., Meyer, K., Steinsland, H., & Hanevik, K. (2024) · Medical Microbiology and Immunology · doi:10.1007/s00430-024-00786-z · Cited by 10

Essential oils ameliorate the intestinal damages induced by nonylphenol exposure by modulating tryptophan metabolism and activating aryl hydrocarbon receptor via gut microbiota regulation

Ge, C., Luo, X., Lv, Y., Wu, L., Hu, Z., Huang, W., Zhan, S., Shen, X., Hui, C., Yu, D., et al. (2024) · Chemosphere · doi:10.1016/j.chemosphere.2024.142571 · Cited by 10

The role of nonesterified fatty acids in cancer biology: Focus on tryptophan and related metabolism

Badawy, A. A.-B. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2024.159531 · Cited by 10

Prostate cancer risk biomarkers from large cohort and prospective metabolomics studies: A systematic review

López‐Hernández, Y., Andrés‐Lacueva, C., Wishart, D. S., Torres-Calzada, C., Martínez‐Huélamo, M., Almanza‐Aguilera, E., & Zamora‐Ros, R. (2024) · Translational Oncology · doi:10.1016/j.tranon.2024.102196 · Cited by 11

High performance and stable rGO/MoS2/NiMgS composite electrode for hybrid supercapacitor and electrochemical sensor applications

Imran, M., Khan, R., Afzal, A. M., Iqbal, M. W., Mumtaz, S., Safdar, S., Yusuf, K., Khalil, S., & Ejaz, T. (2024) · Diamond and Related Materials · doi:10.1016/j.diamond.2024.111879 · Cited by 10

Tryptophan Metabolism Through the Kynurenine Pathway in Glial Cells

Argolo, D. S., de Oliveira, L. M. G., Guillemin, G. J., Barreto, G. E., Butt, A. M., Costa, S. L., & Costa, M. D. F. D. (2025) · Neuroglia · doi:10.3390/neuroglia6010014 · Cited by 11

Promising Gastric Cancer Biomarkers—Focus on Tryptophan Metabolism via the Kynurenine Pathway

Ożga, K., Stepuch, P., Maciejewski, R., & Sadok, I. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26083706 · Cited by 10

Kynurenine pathway dysregulation in cognitive impairment and dementia: a systematic review and meta-analysis

Choe, K., Bakker, L., van den Hove, D., Eussen, S. J. P. M., Kenis, G., Ramakers, I. H. G. B., Verhey, F. R. J., Rutten, B. P. F., & Köhler, S. (2025) · GeroScience · doi:10.1007/s11357-025-01636-3 · Cited by 12

The Microbiota‐Gut‐Brain Axis in the Pathophysiology of Major Depressive Disorder: A Mechanistic Review

Akif, A., & Islam, M. R. (2026) · Comprehensive physiology · doi:10.1002/cph4.70100 · Cited by 12

Kynurenine pathway dysregulation in major depressive disorder: the convergence of excitotoxicity, neuroinflammation, and oxidative stress

O’Regan, G., Plummer, Z., Christie, B. R., Shultz, S. R., & Allen, J. (2026) · Journal of Neuroinflammation · doi:10.1186/s12974-026-03717-2 · Cited by 11

Hypothesis: Metabolic targeting of 5-aminolevulinate synthase by tryptophan and inhibitors of heme utilisation by tryptophan 2,3-dioxygenase as potential therapies of acute hepatic porphyrias

Badawy, A. A. ‐. (2019) · Medical Hypotheses · doi:10.1016/j.mehy.2019.109314 · Cited by 10

Impact of extended-release niacin on immune activation in HIV-infected immunological non-responders on effective antiretroviral therapy

Lebouché, B., Yero, A., Shi, T., Farnós, O., Singer, J., Kema, I. P., Costiniuk, C. T., Thomas, R., Brouillette, M., Engler, K., et al. (2020) · HIV Research & Clinical Practice · doi:10.1080/25787489.2020.1866846 · Cited by 10

Blood metabolomics in infants enrolled in a dose escalation pilot trial of budesonide in surfactant

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Treatment with PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia Lowers Plasma Levels of Platelet-Activating Factor and Its Precursors: A Combined Metabolomic and Lipidomic Approach

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