Self-administered Expanded Disability Status Scale with functional system scores correlates well with a physician-administered test
Abstract
Background Patient-administered measures are needed to assess disability cost-effectively in large epidemiological studies. Setting An outpatient clinic in a large multiple sclerosis center. Methods A self-administered EDSS questionnaire was developed (EDSS-S). Consecutive patients with clinically definite multiple sclerosis completed the EDSS-S (n=95). During the same visit, a physician completed an EDSS (EDSS-P). Scores below 4.0 were determined using functional system (FS) scores. Scores above 4.0 were calculated by two methods, using gait alone and using gait and functional system scores combined. Results EDSS-P scores ranged from 0-9.5 (mean 5.1, median 5.0, 78% female, age 17-78, mean age 45). Mean EDSS-P, EDSS-S and intraclass correlation coefficients of agreement were: EDSS using ambulation alone (4.6, 5.1, 0.89), EDSS using ambulation and FS scores (4.6, 5.3, 0.87), bowel/bladder FS scores (1.6, 1.7, 0.79), pyramidal FS scores (2.1, 2.4, 0.67), sensory FS scores (1.6, 2.1, 0.60), cerebellar FS scores (1.1, 1.6, 0.55), brainstem FS scores (0.5, 1.2, 0.45), vision FS scores (1.9, 1.3, 0.38), cerebral FS scores (0.6, 2.3, 0.27). Conclusions Very good correlation was seen between patient and physician scores for EDSS and the bowel/bladder FS score. Four other FS scores correlated moderately. In general, patients scored themselves more disabled than physicians.
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“Demographic data (age, gender, level of education, employment status, marital status, ethnic background); MS data (MS type, months since first MS symptoms, current disease modifying medication); mental health data (antidepressant medication use, previous diagnosis of depression and anxiety disorder); and level of ambu…”
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- Authors
- Bowen, J., Gibbons, L., Gianas, A., & Kraft, G. H.
- Affiliations
- University of Washington (US)
- Venue
- Multiple Sclerosis Journal
- Publisher
- SAGE Publications
- Published
- 2001-06
- Volume
- 7
- Issue
- 3
- Pages
- 201-206
- ISSN
- 1352-4585 (ISSN-L)
- 1477-0970
- OpenAlex
- W1973096010
- Cited by
- 182
- References
- 1
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 5 · 2023: 6 · 2022: 10 · 2021: 11 · 2020: 9 · 2019: 12 · 2018: 11 · 2017: 14 · 2016: 13 · 2015: 17 · 2014: 8 · 2013: 11 · 2012: 9
- FWCI
- 1.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Multiple Sclerosis Journal (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Disability and Rehabilitation Research
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Medical Practices and Rehabilitation
- Keywords
- Expanded Disability Status Scale, multiple sclerosis, patient-physician agreement, ambulation, bowel and bladder dysfunction, pyramidal signs, gait, disability assessment
- MeSH terms
- Activities of Daily Living, Adolescent, Adult, Aged, Cognition, Disability Evaluation, Female, Gait, Health Status, Humans, Male, Middle Aged, Multiple Sclerosis, Outpatients, Physicians, Surveys and Questionnaires, Severity of Illness Index, Vision, Ocular
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