The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Gait abnormalities in minimally impaired multiple sclerosis patients
Abstract
Subclinical evidence of gait abnormalities were identified in a group of seven patients with Multiple Sclerosis, EDSS scored 0-2, without functional limitations. A movement analysis technique was used to identify gait parameters indicative of impaired motor function during walking. Abnormalities related primarily to time-distance parameters (reduced speed of progression, shorter strides, prolonged double support phase) and muscular function (premature recruitment of gastrocnemius and late relaxation of tibialis anterior during stance phase) were identified regardless the severity of the clinical score. The gait analysis procedure was able to provide the clinician with evidence of motor abnormalities prior to functional disturbance observable by a trained physician. These minimal dysfunctions may have resulted from reflex mechanisms impaired by delayed transmission through long loop pathways or else as a result of a nonspecific protective gait strategy to improve balance control. The technique described in this study may be useful to identify earlier starting points for follow-up and physiotherapy.
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Cites
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Cited by
Gait and balance impairment in early multiple sclerosis in the absence of clinical disability
Martin, C. L., Phillips, B. A., Kilpatrick, T. J., Butzkueven, H., Tubridy, N., McDonald, E., & Galea, M. P. (2006) · Multiple Sclerosis Journal · doi:10.1177/1352458506070658 · Cited by 543
Postural Control in Multiple Sclerosis: Implications for Fall Prevention
Cameron, M. H., & Lord, S. (2010) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-010-0128-0 · Cited by 299
Balance, gait, and falls in multiple sclerosis
(2018) · Handbook of Clinical Neurology · doi:10.1016/b978-0-444-63916-5.00015-x · Cited by 271
A paradigm shift for rehabilitation robotics
Krebs, H., Dipietro, L., Levy-Tzedek, S., Fasoli, S., Rykman-Berland, A., Zipse, J., Fawcett, J., Stein, J., Poizner, H., Lo, A., et al. (2008) · IEEE Engineering in Medicine and Biology Magazine · doi:10.1109/memb.2008.919498 · Cited by 162
Moen, S. M., Celius, E. G., Nordsletten, L., & Holmøy, T. (2011) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2011.01548.x · Cited by 39
Metadata
- Authors
- Benedetti, M. G., Piperno, R., Simoncini, L., Bonato, P., Tonini, A., & Giannini, S.
- Venue
- Multiple Sclerosis Journal
- Publisher
- SAGE Publications
- Published
- 1999-10
- Volume
- 5
- Issue
- 5
- Pages
- 363-368
- ISSN
- 1352-4585 (ISSN-L)
- 1477-0970
- OpenAlex
- W1996474271
- Cited by
- 289
- References
- 17
- FWCI
- 6.35
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Gait abnormalities in minimally impaired multiple sclerosis patients. https://app.cochat.ai/papers/10.1177/135245859900500510
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- Benedetti, M. G., Piperno, R., Simoncini, L., Bonato, P., Tonini, A., & Giannini, S. (1999). Gait abnormalities in minimally impaired multiple sclerosis patients. Multiple Sclerosis Journal. https://doi.org/10.1177/135245859900500510
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
