The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.
Mushrooms, Tumors, and Immunity: An Update
Abstract
There is significant interest in the use of mushrooms and/or mushroom extracts as dietary supplements based on theories that they enhance immune function and promote health. To some extent, select mushrooms have been shown to have stimulatory action on immune responsiveness, particularly when studied in vitro. However, despite their widespread use for potential health benefits, there is a surprising paucity of epidemiologic and experimental studies that address the biologic activities of mushrooms after oral administration to animals or humans. There have been a number of studies that have addressed the ability of mushrooms to modulate mononuclear cell activation and the phenotypic expression of cytokines and their cognate receptors. There have also been a number of attempts to determine antitumor activities of mushrooms. Such studies are important because many of the components of mushrooms do potentially have significant biologic activity. All data, however, should be tempered by the Possibility that there are toxic levels of metals, including arsenic, lead, cadmium, and mercury as well as the presence of radioactive contamination with 137 Cs. In this review, we will Present the comparative biology with respect to both immunological and antitumor activities of mushroom extracts and also highlight the need for further evidence-based research.
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Cites
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Poultry coccidiosis: recent advancements in control measures and vaccine development
Dalloul, R. A., & Lillehoj, H. S. (2006) · Expert Review of Vaccines · doi:10.1586/14760584.5.1.143 · Cited by 607
Phenolic compounds and antimicrobial activity of olive (Olea europaea L. Cv. Cobrançosa) leaves
Pereira, A. P., Ferreira, I. C., Marcelino, F., Valentão, P., Andrade, P. B., Seabra, R., Estevinho, L., Bento, A., & Pereira, J. A. (2007) · Molecules · doi:10.3390/12051153 · Cited by 519
Coccidiosis in poultry: anticoccidial products, vaccines and other prevention strategies
Peek, H. W., & Landman, W. J. M. (2011) · Veterinary Quarterly · doi:10.1080/01652176.2011.605247 · Cited by 398
Antiinflammatory and Immunomodulating Properties of FungalMetabolites
Lull, C., Wichers, H. J., & Savelkoul, H. F. J. (2005) · Mediators of Inflammation · doi:10.1155/mi.2005.63 · Cited by 346
Compounds from Wild Mushrooms with Antitumor Potential
C.F.R. Ferreira, I., A. Vaz, J., Vasconcelos, M. H., & Martins, A. (2010) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/1871520611009050424 · Cited by 334
Metadata
- Authors
- Borchers, A. T., Keen, C. L., & Gershwin, M. E.
- Venue
- Experimental Biology and Medicine
- Publisher
- Frontiers Media SA
- Published
- 2004-05
- Volume
- 229
- Issue
- 5
- Pages
- 393-406
- ISSN
- 0071-3384 (ISSN-L)
- 1535-3702
- 1535-3699
- OpenAlex
- W1795690021
- Cited by
- 381
- References
- 61
- FWCI
- 7.23
- Type
- journal article
- Language
- en
- Open access
- closed
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- Borchers, A. T., Keen, C. L., & Gershwin, M. E. (2004). Mushrooms, Tumors, and Immunity: An Update. Experimental Biology and Medicine. https://doi.org/10.1177/153537020422900507
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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