The DOI matches its Crossref record; 212 of the 212 references it cites were found in a registry or an index.
T he D iagnostic A pplications of S aliva — A R eview
Abstract
This review examines the diagnostic application of saliva for systemic diseases. As a diagnostic fluid, saliva offers distinctive advantages over serum because it can be collected non-invasively by individuals with modest training. Furthermore, saliva may provide a cost-effective approach for the screening of large populations. Gland-specific saliva can be used for diagnosis of pathology specific to one of the major salivary glands. Whole saliva, however, is most frequently used for diagnosis of systemic diseases, since it is readily collected and contains serum constituents. These constituents are derived from the local vasculature of the salivary glands and also reach the oral cavity via the flow of gingival fluid. Analysis of saliva may be useful for the diagnosis of hereditary disorders, autoimmune diseases, malignant and infectious diseases, and endocrine disorders, as well as in the assessment of therapeutic levels of drugs and the monitoring of illicit drug use.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Saliva analysis can also provide a cost-effective approach for screening large populations 153.”
From Glucose biosensors in clinical practice: principles, limits and perspectives of currently used devices (2022) · cites this paper as [153]
In the citing paper
“Saliva is a complex oral fluid, which is produced mainly by the parotid gland and is composed of numerous constituents, such as metabolites, enzymes, hormones, proteins, microorganisms and ions125,135-140.”
From Wearable biosensors for healthcare monitoring (2019) · cites this paper as [136]
Citations
Cites
Items 201–212 of 212
Sreebny, L. M., & Zhu, W. X. (1996) · Gerodontology · doi:10.1111/j.1741-2358.1996.tb00149.x · Cited by 11
Measurement of Platinum in Saliva of Patients Treated with Cisplatin
Holding, J. D., LINDUP, W. E., Roberts, N. B., Salvatori, P., & Stell, P. M. (1999) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/000456329903600515 · Cited by 11
Salivary kallikrein in Sjögren's syndrome.
Friberg, B., Jonsson, R., & Linde, A. (1988) · PubMed · Cited by 11
Hicks, J. M., Carter, A. B., Rossmann, S. N., Demmler, G. J., Simon, C. L., Cron, S. G., FLAITZ, C. M., Shearer, W. T., & Kline, M. W. (1998) · PubMed · Cited by 10
Saliva from cystic fibrosis patients contains an unusual form of epidermal growth factor
Aubert, B., Cochet, C., Souvignet, C., & CHAMBAZ, E. M. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)90512-l · Cited by 10
Salivary kinetics of prednisolone in man
Lowe, J. R., & Dixon, J. S. (1983) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1983.tb02965.x · Cited by 10
A Simple Solid Phase Enzyme Immunoassay for Aldosterone in Plasma and Saliva1)
Hubl, W., Taubebt, H., Freymann, E., Hofmann, F., Meissner, D., Garten, C., Schmidt, P., Hj, T., & Neef, B. (2009) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0029-1210275 · Cited by 9
McSharry, C. P., MacLEOD, McGREGOR, SPEEKENBRINK, SRIRAM, BOYD, & BOYD (1999) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.1999.00591.x · Cited by 8
Bergmann, O. J. (1996) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.1996.tb00195.x · Cited by 8
Practical Applications for Saliva in Perinatal HIV Diagnosisa
Archibald, D. W., Farley, J. J., HEBERT, C. A., Hines, S. E., Nair, P., & Johnson, J. P. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb18353.x · Cited by 6
Cystic fibrosis: protease activity in saliva evaluated with chromogenic substrates.
Kittang, E., Odegaard, O. R., & MICHALSEN, H. (1986) · PubMed · Cited by 4
Research works printed but not linked: 2
- Gaudette D, North L, Hindahl M, Griffin K, Klimkow N, Thieme T (1994). Stability of clinically significant antibodies in saliva and oral fluid. J Clin Immunoassay 17:171–175.
- Young JA, Van Lennep EW (1978). The process of secretion of organic products. In: The morphology of salivary glands. London, UK: Academic Press, pp. 124-144.
Cited by
Sorted by citations
Wearable biosensors for healthcare monitoring
Kim, J., Campbell, A. S., de Ávila, B. E.-F., & Wang, J. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0045-y · Cited by 3,373
Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2017
Hiemke, C., Bergemann, N., Clement, H. ‐., Conca, A., Deckert, J., Domschke, K., Eckermann, G., Egberts, K. M., Gerlach, M., Greiner, C., et al. (2017) · Pharmacopsychiatry · doi:10.1055/s-0043-116492 · Cited by 1,494
Nater, U. M., & Rohleder, N. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.01.014 · Cited by 1,370
Amann, A., Costello, B. D. L., Miekisch, W., Schubert, J., Buszewski, B., Pleil, J., Ratcliffe, N., & Risby, T. (2014) · Journal of Breath Research · doi:10.1088/1752-7155/8/3/034001 · Cited by 804
Diagnostic Potential of Saliva: Current State and Future Applications
Pfaffe, T., Cooper-White, J. J., Beyerlein, P., Kostner, K., & Punyadeera, C. (2011) · Clinical Chemistry · doi:10.1373/clinchem.2010.153767 · Cited by 805
Metadata
- Authors
- Kaufman, E., & Lamster, I. B.
- Affiliations
- Columbia University (US)
- ORCID
- Lamster, Ira B.
- Venue
- Critical Reviews in Oral Biology & Medicine
- Publisher
- SAGE Publications
- Published
- 2002-03
- Volume
- 13
- Issue
- 2
- Pages
- 197-212
- ISSN
- 1045-4411 (ISSN-L)
- 1544-1113
- OpenAlex
- W2084107384
- Cited by
- 887
- References
- 212
- Citations by year
- 2026: 39 · 2025: 32 · 2024: 52 · 2023: 61 · 2022: 39 · 2021: 40 · 2020: 47 · 2019: 43 · 2018: 34 · 2017: 36 · 2016: 38 · 2015: 56 · 2014: 57 · 2013: 52 · 2012: 55
- FWCI
- 0.98
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Critical Reviews in Oral Biology & Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Salivary Gland Disorders and Functions
- Health Sciences › Health Professions › Medical Laboratory Technology › Clinical Laboratory Practices and Quality Control
- Health Sciences › Dentistry › General Dentistry › HIV/AIDS oral health manifestations
- Keywords
- saliva diagnostics, whole saliva, non-invasive biomarkers, systemic disease diagnosis, salivary gland pathology, autoimmune disease, genetic disorders, cancer, infectious diseases, endocrine disorders, therapeutic drug monitoring, mass screening
- MeSH terms
- Animals, Autoimmune Diseases, Communicable Diseases, Hormones, Humans, Mouth Diseases, Saliva, Biomarkers, Drug Monitoring, Clinical Chemistry Tests, Genetic Diseases, Inborn
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
