The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Indocyanine Green: Historical Context, Current Applications, and Future Considerations
Abstract
Background. Indocyanine green (ICG) is a dye used in medicine since the mid-1950s for a variety of applications in in cardiology, ophthalmology, and neurosurgery; however, its fluorescent properties have only recently been used in the intraoperative evaluation of tissue perfusion. Method. A literature review was conducted on the characterization and employment of ICG within the medical field. Historical and current context of ICG was examined while also considering implications for its future use. Results. ICG is a relatively nontoxic, unstable compound bound by albumin in the intravascular space until rapid clearance by the liver. It has widespread uses in hepatic, cardiac, and ophthalmologic studies, and its use in analyzing tissue perfusion and identifying sentinel lymph nodes in cancer staging is gaining popularity. Conclusions. ICG has myriad applications and poses low risk to the patient. Its historical uses have contributed to medical knowledge, and it is now undergoing investigation for quantifying tissue perfusion, providing targeted therapies, and intraoperative identification of neurovascular anatomy, ophthalmic structures, and sentinel lymph nodes. New applications of ICG may lead to reduction in postoperative wound-related complications, more effective ophthalmologic procedures, and better detection and treatment of cancer cells.
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Cites
A Review of Indocyanine Green Fluorescent Imaging in Surgery
Alander, J. T., Kaartinen, I., Laakso, A., Pätilä, T., Spillmann, T., Tuchin, V. V., Venermo, M., & Välisuo, P. (2012) · International Journal of Biomedical Imaging · doi:10.1155/2012/940585 · Cited by 1,352
INDOCYANINE GREEN: OBSERVATIONS ON ITS PHYSICAL PROPERTIES, PLASMA DECAY, AND HEPATIC EXTRACTION*
Cherrick, G. R., Stein, S. W., Leevy, C. M., & Davidson, C. S. (1960) · Journal of Clinical Investigation · doi:10.1172/jci104072 · Cited by 979
Light-absorbing properties, stability, and spectral stabilization of indocyanine green
Landsman, M. L., Kwant, G., Mook, G. A., & Zijlstra, W. G. (1976) · Journal of Applied Physiology · doi:10.1152/jappl.1976.40.4.575 · Cited by 834
Fluorescence Properties and Metabolic Features of Indocyanine Green (ICG) as Related to Angiography
Desmettre, T., Devoisselle, J. M., & Mordon, S. (2000) · Survey of Ophthalmology · doi:10.1016/s0039-6257(00)00123-5 · Cited by 754
Fluorescence navigation with indocyanine green for detecting sentinel lymph nodes in breast cancer
Kitai, T., Inomoto, T., Miwa, M., & Shikayama, T. (2005) · Breast Cancer · doi:10.2325/jbcs.12.211 · Cited by 640
Fluorescence properties of indocyanine green as related to angiography
Benson, R. C., & Kues, H. A. (1978) · Physics in Medicine & Biology · doi:10.1088/0031-9155/23/1/017 · Cited by 432
Rowell, L. B., Blackmon, J. R., & Bruce, R. A. (1964) · Journal of Clinical Investigation · doi:10.1172/jci105043 · Cited by 394
ESTIMATION OF HEPATIC BLOOD FLOW WITH INDOCYANINE GREEN*
Leevy, C. M., Mendenhall, C. L., Lesko, W., & Howard, M. M. (1962) · Journal of Clinical Investigation · doi:10.1172/jci104570 · Cited by 380
Near-Infrared Fluorescence Imaging in Humans with Indocyanine Green: A Review and Update
Marshall, M. V., Rasmussen, J. C., Tan, I.-C., Aldrich, M. B., Adams, K. E., Wang, X., Fife, C. E., Maus, E. A., Smith, L. A., & Sevick-Muraca, E. M. (2010) · The Open Surgical Oncology Journal · doi:10.2174/1876504101002010012 · Cited by 341
Jafari, M. D., Lee, K. H., Halabi, W. J., Mills, S. D., Carmichael, J. C., Stamos, M. J., & Pigazzi, A. (2013) · Surgical Endoscopy · doi:10.1007/s00464-013-2832-8 · Cited by 337
Cited by
In vivo NIR-II fluorescence imaging for biology and medicine
Wang, F., Zhong, Y., Bruns, O., Liang, Y., & Dai, H. (2024) · Nature Photonics · doi:10.1038/s41566-024-01391-5 · Cited by 564
A chemically stable fluorescent marker of the ureter
Cha, J., Nani, R. R., Luciano, M. P., Kline, G., Broch, A., Kim, K., Namgoong, J.-M., Kulkarni, R. A., Meier, J. L., Kim, P., et al. (2018) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2018.02.040 · Cited by 59
Metadata
- Authors
- Reinhart, M. B., Huntington, C. R., Blair, L. J., Heniford, B. T., & Augenstein, V. A.
- Venue
- Surgical Innovation
- Publisher
- SAGE Publications
- Published
- 2015-09-10
- Volume
- 23
- Issue
- 2
- Pages
- 166-175
- ISSN
- 1553-3506 (ISSN-L)
- 1553-3514
- OpenAlex
- W2322133568
- Cited by
- 517
- References
- 41
- FWCI
- 7.64
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
