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Cited by 225Sexual function and dysfunction studiesSexuality, Behavior, and TechnologySex work and related issues

The DOI matches its Crossref record; 155 of the 156 references it cites were found in a registry or an index.

Women’s sexual dysfunction associated with psychiatric disorders and their treatment

Open access
Basson, Rosemary, Gilks, Thea·2018·Women's Health
DOI 10.1177/1745506518762664PMC PMC5900810
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Abstract

Impairment of mental health is the most important risk factor for female sexual dysfunction. Women living with psychiatric illness, despite their frequent sexual difficulties, consider sexuality to be an important aspect of their quality of life. Antidepressant and antipsychotic medication, the neurobiology and symptoms of the illness, past trauma, difficulties in establishing relationships and stigmatization can all contribute to sexual dysfunction. Low sexual desire is strongly linked to depression. Lack of subjective arousal and pleasure are linked to trait anxiety: the sensations of physical sexual arousal may lead to fear rather than to pleasure. The most common type of sexual pain is 10 times more common in women with previous diagnoses of anxiety disorder. Clinicians often do not routinely inquire about their patients’ sexual concerns, particularly in the context of psychotic illness but careful assessment, diagnosis and explanation of their situation is necessary and in keeping with patients’ wishes. Evidence-based pharmacological and non-pharmacological interventions are available but poorly researched in the context of psychotic illness.

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Crossref · 10.1177/1745506518762664

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Figures

Figure 1. Incentive-based model of sexual response. Human sexual response is depicted as a motivation-/incentive-based cycle of overlapping phases of variable order. A sense of desire may or may not be present initially: it can be triggered alongside the sexual arousal resulting from attending to sexual stimuli. Sexual arousal comprises subjective (pleasure/excitement/wanting more of the same), and physical (genital and non-genital responses) components. Psychological and biological factors influence the brain’s appraisal of the sexual stimuli. The sexual and non-sexual outcomes influence present and future sexual motivation. Adapted from Basson.27
Figure 1. Incentive-based model of sexual response. Human sexual response is depicted as a motivation-/incentive-based cycle of overlapping phases of variable order. A sense of desire may or may not be present initially: it can be triggered alongside the sexual arousal resulting from attending to sexual stimuli. Sexual arousal comprises subjective (pleasure/excitement/wanting more of the same), and physical (genital and non-genital responses) components. Psychological and biological factors influence the brain’s appraisal of the sexual stimuli. The sexual and non-sexual outcomes influence present and future sexual motivation. Adapted from Basson.27CC BY-NC · PubMed Central
Figure 2. Sexual response cycle is potentially weakened by depression at all points in an incentive-based model of sexual response. Depression diminishes sexual incentives: anhedonia lessens the wanting of physical pleasure; depression reduces emotional intimacy—a major sexual incentive for women. There is little effort to secure needed sexual stimuli and sexual context. Sexual information processing in the brain is severely compromised by poor concentration and non-erotic thoughts and emotions leading to minimal arousal and no triggered desire. Neurotransmitters modulating sexual arousal are altered in depression. Outcome is unsatisfactory physically and emotionally and does not motivate further sexual interaction.
Figure 2. Sexual response cycle is potentially weakened by depression at all points in an incentive-based model of sexual response. Depression diminishes sexual incentives: anhedonia lessens the wanting of physical pleasure; depression reduces emotional intimacy—a major sexual incentive for women. There is little effort to secure needed sexual stimuli and sexual context. Sexual information processing in the brain is severely compromised by poor concentration and non-erotic thoughts and emotions leading to minimal arousal and no triggered desire. Neurotransmitters modulating sexual arousal are altered in depression. Outcome is unsatisfactory physically and emotionally and does not motivate further sexual interaction.CC BY-NC · PubMed Central

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Cites

Show all 156 references

Research works printed but not linked: 14

  1. Mitchell KR, 2013, Lancet, 26, 1
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Metadata

Authors
Basson, R., & Gilks, T.
Affiliations
University of British Columbia (CA)
Corresponding author
Basson, Rosemary
ORCID
Basson, Rosemary
Venue
Women's Health
Publisher
SAGE Publications
Published
2018-01-01
Volume
14
Pages
1745506518762664-1745506518762664
ISSN
  • 1745-5057 (ISSN-L)
  • 1745-5065
DOI
10.1177/1745506518762664
PMC
PMC5900810
OpenAlex
W2797764559
Cited by
225
References
156
Citations by year
2026: 28 · 2025: 29 · 2024: 43 · 2023: 41 · 2022: 32 · 2021: 23 · 2020: 20 · 2019: 7 · 2018: 2
FWCI
10.23
Type
journal article
Language
en
Open access
Licence
Locations
  • Women s Health (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
  • Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
  • Social Sciences › Sociology and Political Science › Sex work and related issues
Keywords
female sexual dysfunction, mental illness, depression, anxiety disorders, antipsychotic drugs, antidepressant side effects, sexual desire, sexual arousal, sexual pain, psychosis, sexual health assessment, quality of life, stigma
MeSH terms
Anxiety, Arousal, Depression, Female, Humans, Libido, Sexual Behavior, Sexual Dysfunction, Physiological, Women's Health, Sexual Dysfunctions, Psychological

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