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Women’s sexual dysfunction associated with psychiatric disorders and their treatment
Open accessAbstract
Impairment of mental health is the most important risk factor for female sexual dysfunction. Women living with psychiatric illness, despite their frequent sexual difficulties, consider sexuality to be an important aspect of their quality of life. Antidepressant and antipsychotic medication, the neurobiology and symptoms of the illness, past trauma, difficulties in establishing relationships and stigmatization can all contribute to sexual dysfunction. Low sexual desire is strongly linked to depression. Lack of subjective arousal and pleasure are linked to trait anxiety: the sensations of physical sexual arousal may lead to fear rather than to pleasure. The most common type of sexual pain is 10 times more common in women with previous diagnoses of anxiety disorder. Clinicians often do not routinely inquire about their patients’ sexual concerns, particularly in the context of psychotic illness but careful assessment, diagnosis and explanation of their situation is necessary and in keeping with patients’ wishes. Evidence-based pharmacological and non-pharmacological interventions are available but poorly researched in the context of psychotic illness.
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“After all, a female brain cannot simultaneously turn off BT-related impulses and turn on sexual impulses (Basson & Gilks, 2018;Fleming, 2005;Nowak et al., 2023).”
From “Your Addiction, her Sexual Suffering”—A Qualitative Inquiry into the Effects of Compulsive Sexual Behaviors on Intimate Female Partners (2025) · cites this paper as Basson & Gilks, 2018
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“One of the most important causes of sexual dysfunction in women is depression, which has been proven in various studies [40, 41].”
From Effect of l-arginine compared to placebo on sexual function in women with major depressive disorder: a randomized controlled trial (2024) · cites this paper as [41]
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“The greatest significant risk factor for female sexual dysfunction is mental health deterioration (Basson & Gilks, 2018, Blycker, 2023;Leeners et al., 2014).”
From “Your Addiction, her Sexual Suffering”—A Qualitative Inquiry into the Effects of Compulsive Sexual Behaviors on Intimate Female Partners (2025) · cites this paper as Basson & Gilks, 2018
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An Exploration of Sexual Desire and Sexual Activities of Women with Psychosis
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Does Surgical Menopause Affect Sexual Performance Differently from Natural Menopause?
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A Review of the Literature on the Selegiline Transdermal System
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Sexual Dysfunction in Female Hemodialysis Patients: a Multicenter Study
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Metadata
- Authors
- Basson, R., & Gilks, T.
- Affiliations
- University of British Columbia (CA)
- Corresponding author
- Basson, Rosemary
- ORCID
- Basson, Rosemary
- Venue
- Women's Health
- Publisher
- SAGE Publications
- Published
- 2018-01-01
- Volume
- 14
- Pages
- 1745506518762664-1745506518762664
- ISSN
- 1745-5057 (ISSN-L)
- 1745-5065
- PMC
- PMC5900810
- OpenAlex
- W2797764559
- Cited by
- 225
- References
- 156
- Citations by year
- 2026: 28 · 2025: 29 · 2024: 43 · 2023: 41 · 2022: 32 · 2021: 23 · 2020: 20 · 2019: 7 · 2018: 2
- FWCI
- 10.23
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Women s Health (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
- Social Sciences › Sociology and Political Science › Sex work and related issues
- Keywords
- female sexual dysfunction, mental illness, depression, anxiety disorders, antipsychotic drugs, antidepressant side effects, sexual desire, sexual arousal, sexual pain, psychosis, sexual health assessment, quality of life, stigma
- MeSH terms
- Anxiety, Arousal, Depression, Female, Humans, Libido, Sexual Behavior, Sexual Dysfunction, Physiological, Women's Health, Sexual Dysfunctions, Psychological
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