The Physiology of Glucagon

Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas.

Mojsov, S., Weir, G. C., & Habener, J. F. (1987) · Journal of Clinical Investigation · doi:10.1172/jci112855 · Cited by 882 · see citing works

Induction of intestinal epithelial proliferation by glucagon-like peptide 2.

Drucker, D. J., Erlich, P., Asa, S. L., & Brubaker, P. L. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.15.7911 · Cited by 880 · see citing works

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing

Mojsov, S., Heinrich, G., Wilson, I. B., Ravazzola, M., Orci, L., & Habener, J. F. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67324-7 · Cited by 724 · see citing works

Lack of Glucagon Response to Hypoglycemia in Diabetes: Evidence for an Intrinsic Pancreatic Alpha Cell Defect

Gerich, J. E., Langlois, M., Noacco, C., Karam, J. H., & Forsham, P. H. (1973) · Science · doi:10.1126/science.182.4108.171 · Cited by 688 · see citing works

Essential role of brain-derived neurotrophic factor in adult hippocampal function

Monteggia, L. M., Barrot, M., Powell, C. M., Berton, O., Galanis, V., Gemelli, T., Meuth, S., Nagy, A., Greene, R. W., & Nestler, E. J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402141101 · Cited by 685 · see citing works

Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans.

Heller, S. R., & Cryer, P. E. (1991) · Diabetes · doi:10.2337/diab.40.2.223 · Cited by 531 · see citing works

Unique Arrangement of α- and β-Cells in Human Islets of Langerhans

Bosco, D., Armanet, M., Morel, P., Niclauss, N., Sgroi, A., Muller, Y. D., Giovannoni, L., Parnaud, G., & Berney, T. (2010) · Diabetes · doi:10.2337/db09-1177 · Cited by 450 · see citing works

Abnormal Glucose Counterregulation in Insulin-dependent Diabetes Mellitus: Interaction of Anti-Insulin Antibodies and Impaired Glucagon and Epinephrine Secretion

Bolli, G., Feo, P. D., Compagnucci, P., Cartechini, M. G., Angeletti, G., Santeusanio, F., Brunetti, P., & Gerich, J. E. (1983) · Diabetes · doi:10.2337/diab.32.2.134 · Cited by 433 · see citing works

Vagal, Cholinergic Regulation of Pancreatic Polypeptide Secretion

Schwartz, T. W., Holst, J. J., Fahrenkrug, J., Jensen, S. L., Nielsen, O. V., Rehfeld, J. F., de Muckadell, O. B. S., & STADIL, F. (1978) · Journal of Clinical Investigation · doi:10.1172/jci108992 · Cited by 386 · see citing works

Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats.

Borg, M. A., Sherwin, R. S., Borg, W. P., Tamborlane, W. V., & Shulman, G. I. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119165 · Cited by 359 · see citing works

STUDIES ON THE CONDITIONS OF ACTIVITY IN ENDOCRINE GLANDS

Cannon, W. B., McIver, M. A., & Bliss, S. W. (1924) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1924.69.1.46 · Cited by 358 · see citing works

The role of adrenergic mechanisms in the substrate and hormonal response to insulin-induced hypoglycemia in man.

Garber, A. J., Cryer, P. E., Santiago, J. V., Haymond, M. W., Pagliara, A. S., & Kipnis, D. M. (1976) · Journal of Clinical Investigation · doi:10.1172/jci108460 · Cited by 351 · see citing works

Hypoglycemia-associated autonomic failure in advanced type 2 diabetes.

Segel, S. A., Paramore, D. S., & Cryer, P. E. (2002) · Diabetes · doi:10.2337/diabetes.51.3.724 · Cited by 337 · see citing works

Insulin Regulation of Lipolysis in Nondiabetic and IDDM Subjects

Jensen, M. D., Caruso, M., Heiling, V. J., & Miles, J. M. (1989) · Diabetes · doi:10.2337/diab.38.12.1595 · Cited by 331 · see citing works

Cholinergic neurons and terminal fields revealed by immunohistochemistry for the vesicular acetylcholine transporter. I. Central nervous system

Schäfer, M. K.-H., Eiden, L. E., & Weihe, E. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00516-2 · Cited by 323 · see citing works

Influence of hyperinsulinemia, hyperglycemia, and the route of glucose administration on splanchnic glucose exchange

DeFronzo, R. A., Ferrannini, E., Hendler, R., Wahren, J., & Felig, P. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.10.5173 · Cited by 296 · see citing works

β-Cell Secretory Products Activate α-Cell ATP-Dependent Potassium Channels to Inhibit Glucagon Release

Franklin, I., Gromada, J., Gjinovci, A., Theander, S., & Wollheim, C. (2005) · Diabetes · doi:10.2337/diabetes.54.6.1808 · Cited by 291 · see citing works

Glucagon: molecular physiology, clinical and therapeutic implications

Lefèbvre, P. J., & Unger, R. H. (1972) · Medical Entomology and Zoology · Cited by 268 · see citing works

Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia.

Borg, W. P., During, M. J., Sherwin, R. S., Borg, M. A., Brines, M. L., & Shulman, G. I. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117150 · Cited by 265 · see citing works

Glucose Inhibition of Glucagon Secretion From Rat α-Cells Is Mediated by GABA Released From Neighboring β-Cells

Wendt, A., Birnir, B., Buschard, K., Gromada, J., Salehi, A. A., Sewing, S., Rorsman, P., & Braun, M. (2004) · Diabetes · doi:10.2337/diabetes.53.4.1038 · Cited by 259 · see citing works

The role of insulin and glucagon in the regulation of basal glucose production in the postabsorptive dog.

Cherrington, A. D., Chiasson, J. L., Liljenquist, J. E., Jennings, A. S., Keller, U., & Lacy, W. W. (1976) · Journal of Clinical Investigation · doi:10.1172/jci108596 · Cited by 249 · see citing works

Characterization of the Effects of Arginine and Glucose on Glucagon and Insulin Release from the Perfused Rat Pancreas

Gerich, J. E., Charles, M. A., & Grodsky, G. M. (1974) · Journal of Clinical Investigation · doi:10.1172/jci107823 · Cited by 230 · see citing works

Hyperglucagonemia in diabetic ketoacidosis

Müller, W. A., Faloona, G. R., & Unger, R. H. (1973) · The American Journal of Medicine · doi:10.1016/0002-9343(73)90083-1 · Cited by 221 · see citing works

Endocrine regulation of protein breakdown in skeletal muscle

Kettelhut, Í. D. C., Wing, S. S., & Goldberg, A. L. (1988) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610040805 · Cited by 197 · see citing works

Intraislet Hyperinsulinemia Prevents the Glucagon Response to Hypoglycemia Despite an Intact Autonomic Response

Banarer, S., McGregor, V. P., & Cryer, P. E. (2002) · Diabetes · doi:10.2337/diabetes.51.4.958 · Cited by 194 · see citing works

Role of Brain in Counterregulation of Insulin-Induced Hypoglycemia in Dogs

Biggers, D. W., Myers, S. R., Neal, D. W., Stinson, R. L., Cooper, N. B., Jaspan, J. B., Williams, P. E., Cherrington, A. D., & Frizzell, R. T. (1989) · Diabetes · doi:10.2337/diab.38.1.7 · Cited by 192 · see citing works

Hormonal mechanisms of recovery from insulin-induced hypoglycemia in man.

Gerich, J., Davis, J., Lorenzi, M., Rizza, R., Bohannon, N., Karam, J., Lewis, S., Kaplan, R., Schultz, T., & Cryer, P. (1979) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1979.236.4.e380 · Cited by 183 · see citing works

Chronic hypoglycemia increases brain glucose transport

McCall, A. L., Fixman, L. B., Fleming, N., Tornheim, K., Chick, W., & Ruderman, N. B. (1986) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1986.251.4.e442 · Cited by 174 · see citing works

Role of cortisol in the pathogenesis of deficient counterregulation after antecedent hypoglycemia in normal humans

Davis, S. N., Shavers, C., Costa, F., & Mosqueda-Garcia, R. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118839 · Cited by 173 · see citing works

Cholinergic neurons and terminal fields revealed by immunohistochemistry for the vesicular acetylcholine transporter. II. The peripheral nervous system

Schäfer, M. K.-H., Eiden, L. E., & Weihe, E. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)80196-0 · Cited by 170 · see citing works

Evidence for an important role of glucagon in the regulation of hepatic glucose production in normal man.

LILJENQUIST, J. E., Mueller, G., Cherrington, A. D., Keller, U. B., Chiasson, J. L., Perry, J., LACY, W. W., & Rabinowitz, D. L. (1977) · Journal of Clinical Investigation · doi:10.1172/jci108649 · Cited by 164 · see citing works

Stimulation of Glucagon Secretion by Epinephrine in Man

GERICH, J. E., KARAM, J. H., & FORSHAM, P. H. (1973) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-37-3-479 · Cited by 164 · see citing works

Loss of the Decrement in Intraislet Insulin Plausibly Explains Loss of the Glucagon Response to Hypoglycemia in Insulin-Deficient Diabetes

Raju, B., & Cryer, P. E. (2005) · Diabetes · doi:10.2337/diabetes.54.3.757 · Cited by 155 · see citing works

Correlation Between Minimal Secretory Capacity of Pancreatic β-Cells and Stability of Diabetic Control

Fukuda, M., Tanaka, A., Tahara, Y., Ikegami, H., Yamamoto, Y., Kumahara, Y., & Shima, K. (1988) · Diabetes · doi:10.2337/diab.37.1.81 · Cited by 145 · see citing works

Sympathetic nerve stimulation versus pancreatic norepinephrine infusion in the dog: 1). Effects on basal release of insulin and glucagon.

Bo, A.-R., Veith, R., & Taborsky, G. (1987) · Endocrinology · doi:10.1210/endo-121-1-323 · Cited by 145 · see citing works

Insulin Reciprocally Regulates Glucagon Secretion in Humans

Cooperberg, B. A., & Cryer, P. E. (2010) · Diabetes · doi:10.2337/db10-0728 · Cited by 145 · see citing works

Glucagon Release Induced by Pancreatic Nerve Stimulation in the Dog

Marliss, E. B., Girardier, L., Seydoux, J., Wollheim, C. B., Kanazawa, Y., Orci, L., Renold, A. E., & Porte, D. (1973) · Journal of Clinical Investigation · doi:10.1172/jci107292 · Cited by 141 · see citing works

Species differences in vasopressin receptor binding are evident early in development: Comparative anatomic studies in prairie and montane voles

Wang, Z., Young, L. J., Liu, Y., & Insel, T. R. (1997) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19970224)378:4 · Cited by 135 · see citing works

Glucagon Secretion from the Perfused Pancreas of Streptozotocin-treated Rats

Weir, G. C., Knowlton, S. D., Atkins, R. F., McKennan, K. X., & Martin, D. B. (1976) · Diabetes · doi:10.2337/diab.25.4.275 · Cited by 122 · see citing works

The Mechanism of Vagal Nerve Stimulation of Glucagon and Insulin Secretion in the Dog*

Åhrén, B., & Taborsky, G. J. (1986) · Endocrinology · doi:10.1210/endo-118-4-1551 · Cited by 122 · see citing works

Zinc, Not Insulin, Regulates the Rat α-Cell Response to Hypoglycemia In Vivo

Zhou, H., Zhang, T., Harmon, J. S., Bryan, J., & Robertson, R. P. (2007) · Diabetes · doi:10.2337/db06-1454 · Cited by 122 · see citing works

In vivo inhibition of glucagon secretion by paracrine beta cell activity in man.

Asplin, C. M., Paquette, T. L., & Palmer, J. (1981) · Journal of Clinical Investigation · doi:10.1172/jci110251 · Cited by 119 · see citing works

Intra-islet insulin permits glucose to directly suppress pancreatic A cell function.

Greenbaum, C. J., Havel, P. J., Taborsky, G. J., & Klaff, L. J. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115375 · Cited by 106 · see citing works

Regulation of α-Cell Function by the β-Cell During Hypoglycemia in Wistar Rats: the “Switch-off” Hypothesis

Zhou, H., Tran, P. O. T., Yang, S., Zhang, T., LeRoy, E., Oseid, E. A., & Robertson, R. P. (2004) · Diabetes · doi:10.2337/diabetes.53.6.1482 · Cited by 99 · see citing works

Early, Selective, and Marked Loss of Sympathetic Nerves From the Islets of BioBreeder Diabetic Rats

Mei, Q., Mundinger, T. O., Lernmark, Å., & Taborsky, G. J. (2002) · Diabetes · doi:10.2337/diabetes.51.10.2997 · Cited by 97 · see citing works

Influence of Insulin in the Ventromedial Hypothalamus on Pancreatic Glucagon Secretion In Vivo

Paranjape, S., Chan, O. T. M., Zhu, W., Horblitt, A. M., McNay, E. C., Cresswell, J. A., Bogan, J. S., McCrimmon, R. J., & Sherwin, R. S. (2010) · Diabetes · doi:10.2337/db10-0014 · Cited by 94 · see citing works

Activation of Autonomic Nerves and the Adrenal Medulla Contributes to Increased Glucagon Secretion During Moderate Insulin-Induced Hypoglycemia in Women

Havel, P. J., & Åhrén, B. (1997) · Diabetes · doi:10.2337/diab.46.5.801 · Cited by 91 · see citing works

Corticotrophin-releasing factor receptors within the ventromedial hypothalamus regulate hypoglycemia- induced hormonal counterregulation

McCrimmon, R. J. (2006) · Journal of Clinical Investigation · doi:10.1172/jci27775 · Cited by 86 · see citing works

A quantitative analysis of the sensory and sympathetic innervation of the mouse pancreas

Lindsay, T. H., Halvorson, K. G., Peters, C. M., Ghilardi, J. R., Kuskowski, M. A., Wong, G. Y., & Mantyh, P. W. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.10.055 · Cited by 78 · see citing works

Pancreatic endocrine responses to stimulation of the peripheral ends of the vagus nerves in conscious calves.

Bloom, S. R., & Edwards, A. V. (1981) · The Journal of Physiology · doi:10.1113/jphysiol.1981.sp013730 · Cited by 74 · see citing works

Importance of hypoglycemia-induced glucose production during isolated glucagon deficiency.

Cherrington, A. D., LILJENQUIST, J. E., Shulman, G. I., Williams, P. E., & LACY, W. W. (1979) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1979.236.3.e263 · Cited by 67 · see citing works

Hypoglycemia Begets Hypoglycemia in IDDM

Cryer, P. E. (1993) · Diabetes · doi:10.2337/diab.42.12.1691 · Cited by 67 · see citing works

Mechanisms of glucagon secretion during insulin-induced hypoglycemia in man. Role of the beta cell and arterial hyperinsulinemia.

Bolli, G., De Feo, P., Perriello, G., De Cosmo, S., Compagnucci, P., Santeusanio, F., Brunetti, P., & Unger, R. H. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111315 · Cited by 64 · see citing works

Pancreatic noradrenergic nerves are activated by neuroglucopenia but not by hypotension or hypoxia in the dog. Evidence for stress-specific and regionally selective activation of the sympathetic nervous system.

Havel, P. J., Veith, R. C., Dunning, B. E., & Taborsky, G. J. (1988) · Journal of Clinical Investigation · doi:10.1172/jci113763 · Cited by 61 · see citing works

Loss of islet sympathetic nerves and impairment of glucagon secretion in the NOD mouse: relationship to invasive insulitis

Taborsky, G. J., Mei, Q., Hackney, D. J., Figlewicz, D. P., LeBoeuf, R. C., & Mundinger, T. O. (2009) · Diabetologia · doi:10.1007/s00125-009-1494-5 · Cited by 59 · see citing works

Role of Glucagon in Diabetes

Unger, R. H. (1977) · Archives of Internal Medicine · doi:10.1001/archinte.1977.03630160050012 · Cited by 55 · see citing works

Parasympathetic Innervation and Function of Endocrine Pancreas Requires the Glial Cell Line–Derived Factor Family Receptor α2 (GFRα2)

Rossi, J., Santamäki, P., Airaksinen, M. S., & Herzig, K.-H. (2005) · Diabetes · doi:10.2337/diabetes.54.5.1324 · Cited by 55 · see citing works

Autonomic control of pancreatic polypeptide and glucagon secretion during neuroglucopenia and hypoglycemia in mice

Havel, P. J., Akpan, J. O., CURRY, D. L., Stern, J. S., Gingerich, R. L., & Åhrén, B. (1993) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1993.265.1.r246 · Cited by 51 · see citing works

Epinephrine Secretion, Hypoglycemia Unawareness, and Diabetic Autonomic Neuropathy

Hoeldtke, R. D., & Boden, G. (1994) · Annals of Internal Medicine · doi:10.7326/0003-4819-120-6-199403150-00011 · Cited by 49 · see citing works

Age at Onset of Type 1 Diabetes in Parents and Recurrence Risk in Offspring

Harjutsalo, V., Lammi, N., Karvonen, M., & Groop, P. (2009) · Diabetes · doi:10.2337/db09-0344 · Cited by 46 · see citing works

Redundant parasympathetic and sympathoadrenal mediation of increased glucagon secretion during insulin-induced hypoglycemia in conscious rats

Havel, P. J., Parry, S. J., Stern, J. S., Akpan, J. O., Gingerich, R. L., Taborsky, G. J., & CURRY, D. L. (1994) · Metabolism · doi:10.1016/0026-0495(94)90267-4 · Cited by 40 · see citing works

Role for Autonomic Nervous System to Increase Pancreatic Glucagon Secretion During Marked Insulin-Induced Hypoglycemia in Dogs

Havel, P. J., Veith, R. C., Dunning, B. E., & Taborsky, G. J. (1991) · Diabetes · doi:10.2337/diab.40.9.1107 · Cited by 40 · see citing works

Pancreatic sympathetic nerves contribute to increased glucagon secretion during severe hypoglycemia in dogs

Havel, P. J., Mundinger, T. O., & Taborsky, G. J. (1996) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1996.270.1.e20 · Cited by 40 · see citing works

Autonomic Mediation of Glucagon Secretion During Insulin-Induced Hypoglycemia in Rhesus Monkeys

Havel, P. J., & Valverde, C. R. (1996) · Diabetes · doi:10.2337/diab.45.7.960 · Cited by 39 · see citing works

Effect of Oral Amino Acids on Counterregulatory Responses and Cognitive Function During Insulin-Induced Hypoglycemia in Nondiabetic and Type 1 Diabetic People

Rossetti, P., Porcellati, F., Ricci, N. B., Candeloro, P., Cioli, P., Nair, K. S., Santeusanio, F., Bolli, G. B., & Fanelli, C. G. (2008) · Diabetes · doi:10.2337/db08-0276 · Cited by 39 · see citing works

Neuropeptide Y and peptide YY immunoreactivities in the pancreas of various vertebrates.

Ding, W.-G., Kimura, H., Fujimura, M., & Fujimiya, M. (1997) · Peptides · doi:10.1016/s0196-9781(97)00237-4 · Cited by 31 · see citing works

Glycemic Actions of Alanine and Terbutaline in IDDM

Wiethop, B. V., & Cryer, P. E. (1993) · Diabetes Care · doi:10.2337/diacare.16.8.1124 · Cited by 27 · see citing works

Direct quantification of norepinephrine spillover and hormone output from the pancreas of the conscious dog

Dunning, B. E., Scott, M. F., Neal, D. W., & Cherrington, A. D. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.272.5.e746 · Cited by 25 · see citing works

Hepatic denervation does not significantly change the response of the liver to glucagon in conscious dogs

Wada, M., Connolly, C. C., Tarumi, C., Neal, D. W., & Cherrington, A. D. (1995) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1995.268.2.e194 · Cited by 23 · see citing works

Loss of Potentiating Effect of Hypoglycemia on the Glucagon Response to Hyperaminoacidemia in IDDM

Caprio, S., Tamborlane, W. V., Zych, K., Gerow, K., & Sherwin, R. S. (1993) · Diabetes · doi:10.2337/diab.42.4.550 · Cited by 21 · see citing works

Role of parasympathetic nervous system in glucagon response to insulin-induced hypoglycemia in normal and diabetic rats

Patel, D. G. (1984) · Metabolism · doi:10.1016/0026-0495(84)90098-2 · Cited by 19 · see citing works

Rates of glucagon activation and deactivation of hepatic glucose production in conscious dogs

Dobbins, R. L., Davis, S. N., Neal, D. W., Caumo, A., Cobelli, C., & Cherrington, A. D. (1998) · Metabolism · doi:10.1016/s0026-0495(98)90209-8 · Cited by 19 · see citing works

Hepatic glucagon clearance during insulin induced hypoglycemia

Herold, K., & Jaspan, J. (1986) · Hormone and Metabolic Research · doi:10.1055/s-2007-1012339 · Cited by 16 · see citing works

Morphologic and Functional Changes in Sympathetic Nerve Relationships With Pancreatic α-Cells After Destruction of β-Cells in Rats

Tominaga, M., Maruyama, H., Vasko, M. R., Baetens, D., Orci, L., & Unger, R. H. (1987) · Diabetes · doi:10.2337/diab.36.3.365 · Cited by 16 · see citing works

Pentobarbital suppresses basal and reflexive pancreatic polypeptide release in dogs

Taborsky, G. J., Paquette, T. L., Pfeifer, M. A., & Gingerich, R. L. (1985) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1985.249.6.e577 · Cited by 11 · see citing works

Glucagon Signal‐Transduction Mechanisms

Exton, J. H. (2001) · Comprehensive physiology · doi:10.1002/cphy.cp070213 · Cited by 1 · see citing works

Incretin therapies: highlighting common features and differences in the modes of action of glucagon‐like peptide‐1 receptor agonists and dipeptidyl peptidase‐4 inhibitors

Nauck, M. (2016) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.12591 · Cited by 429 · see citing works

The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans

Tirosh, A., Calay, E. S., Tuncman, G., Claiborn, K. C., Inouye, K., Eguchi, K., Alcala, M., RATHAUS, M., Hollander, K. S., Ron, I., et al. (2019) · Science Translational Medicine · doi:10.1126/scitranslmed.aav0120 · Cited by 297 · see citing works

Insulin resistance: An adaptive mechanism becomes maladaptive in the current environment—An evolutionary perspective

Tsatsoulis, A., Mantzaris, M. D., Bellou, S., & Andrikoula, M. (2013) · Metabolism · doi:10.1016/j.metabol.2012.11.004 · Cited by 174 · see citing works

Randomized Outpatient Trial of Single- and Dual-Hormone Closed-Loop Systems That Adapt to Exercise Using Wearable Sensors

Castle, J. R., El Youssef, J., Wilson, L. M., Reddy, R., Resalat, N., Branigan, D., Ramsey, K., Leitschuh, J., Rajhbeharrysingh, U., Senf, B., et al. (2018) · Diabetes Care · doi:10.2337/dc18-0228 · Cited by 152 · see citing works

The Biology of Glucagon and the Consequences of Hyperglucagonemia

Albrechtsen, N. J. W., Kuhre, R. E., Pedersen, J., Knop, F. K., & Holst, J. J. (2016) · Biomarkers in Medicine · doi:10.2217/bmm-2016-0090 · Cited by 124 · see citing works

Neural control of the endocrine pancreas.

Rodriguez-Diaz, R., & Caicedo, A. (2014) · Best practice & research. Clinical endocrinology & metabolism · doi:10.1016/j.beem.2014.05.002 · Cited by 76 · see citing works

Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis

Galsgaard, K. D., Winther‐Sørensen, M., Ørskov, C., Kissow, H., Poulsen, S. S., Vilstrup, H., Prehn, C. P., Adamski, J., Jepsen, S. L., Hartmann, B., et al. (2017) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00198.2017 · Cited by 117 · see citing works

Pharmacokinetic and pharmacodynamic characteristics of dasiglucagon, a novel soluble and stable glucagon analog

Hövelmann, U., Bysted, B. V., Mouritzen, U., Macchi, F., Lamers, D., Kronshage, B., Møller, D. V., & Heise, T. (2018) · Diabetes Care · doi:10.2337/dc17-1402 · Cited by 115 · see citing works

Central mechanisms of glucose sensing and counterregulation in defense of hypoglycemia

Stanley, S., Moheet, A., & Seaquist, E. R. (2019) · Endocrine Reviews · doi:10.1210/er.2018-00226 · Cited by 112 · see citing works

Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State

Maletkovic, J., & Drexler, A. (2013) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2013.07.001 · Cited by 91 · see citing works

Management of Diabetic Ketoacidosis in Children and Adolescents with Type 1 Diabetes Mellitus

Castellanos, L. E., Tuffaha, M., Koren, D., & Levitsky, L. L. (2020) · Pediatric Drugs · doi:10.1007/s40272-020-00397-0 · Cited by 89 · see citing works

A review of biomarkers in the context of type 1 diabetes: Biological sensing for enhanced glucose control

Wolkowicz, K. L., Aiello, E. M., Vargas, E., Teymourian, H., Tehrani, F., Wang, J., Pinsker, J. E., Doyle, F. J., Patti, M., Laffel, L. M., et al. (2020) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10201 · Cited by 79 · see citing works

Stress-induced hyperglycaemia in non-diabetic patients with acute coronary syndrome: from molecular mechanisms to new therapeutic perspectives

Bellis, A., Mauro, C., Barbato, E., Ceriello, A., Cittadini, A., & Morisco, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22020775 · Cited by 61 · see citing works

Long-term elevation of β-hydroxybutyrate in dairy cows through infusion: Effects on feed intake, milk production, and metabolism

Zarrin, M., Matteis, L. D., Vernay, M. C. M. B., Wellnitz, O., van Dorland, H. A., & Bruckmaier, R. M. (2013) · Journal of Dairy Science · doi:10.3168/jds.2012-6224 · Cited by 62 · see citing works

Glucagon's Metabolic Action in Health and Disease

Zeigerer, A., Sekar, R., Kleinert, M., Nason, S. R., Habegger, K. M., & Müller, T. D. (2021) · Comprehensive physiology · doi:10.1002/cphy.c200013 · Cited by 76 · see citing works

Glucagon in artificial pancreas systems: Potential benefits and safety profile of future chronic use

Taleb, N., Haidar, A., Messier, V., Gingras, V., Legault, L., & RABASA-LHORET, R. P. R. (2016) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12789 · Cited by 59 · see citing works

Glucagon orchestrates stress‐induced hyperglycaemia

Harp, J. B., Yancopoulos, G. D., & Gromada, J. (2016) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12668 · Cited by 58 · see citing works

Nutrient regulation of glucagon secretion: involvement in metabolism and diabetes

Marroquí, L., Alonso‐Magdalena, P., Merino, B., Fuentes, E., Nadal, Á., & Quesada, I. (2014) · Nutrition Research Reviews · doi:10.1017/s0954422414000031 · Cited by 55 · see citing works

Ketogenic Diet: an Endocrinologist Perspective

Kuchkuntla, A. R., Shah, M., Velapati, S. R., Gershuni, V. M., Rajjo, T. I., Nanda, S., Hurt, R. T., & Mundi, M. S. (2019) · Current Nutrition Reports · doi:10.1007/s13668-019-00297-x · Cited by 51 · see citing works

Ghrelin, the proglucagon-derived peptides and peptide YY in nutrient homeostasis

Dong, C. X., & Brubaker, P. L. (2012) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2012.185 · Cited by 43 · see citing works

The Complex Exocrine–Endocrine Relationship and Secondary Diabetes in Exocrine Pancreatic Disorders

Chen, N., Ranjit Unnikrishnan, I., Anjana, R. M., Mohan, V., & Pitchumoni, C. S. (2011) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e31822a2ae5 · Cited by 43 · see citing works

Hypoglycaemia unawareness in patients with type 1 diabetes

Szadkowska, A., Czyżewska, K., Pietrzak, I., Mianowska, B., Jarosz-Chobot, P. A., & Myśliwiec, M. (2018) · Pediatric Endocrinology Diabetes and Metabolism · doi:10.5114/pedm.2018.80994 · Cited by 41 · see citing works

Cross Talk Between Insulin and Glucagon Receptor Signaling in the Hepatocyte

Habegger, K. M. (2022) · Diabetes · doi:10.2337/dbi22-0002 · Cited by 40 · see citing works

Safe Glycemic Management during Closed-Loop Treatment of Type 1 Diabetes: The Role of Glucagon, Use of Multiple Sensors, and Compensation for Stress Hyperglycemia

Ward, W. K., Castle, J. R., & Youssef, J. E. (2011) · Journal of Diabetes Science and Technology · doi:10.1177/193229681100500608 · Cited by 36 · see citing works

Glucagon, cyclic AMP, and hepatic glucose mobilization: A half‐century of uncertainty

Rodgers, R. L. (2022) · Physiological Reports · doi:10.14814/phy2.15263 · Cited by 33 · see citing works

Glucagon‐like peptide ‐1 receptor agonists as adjunctive treatment for type 1 diabetes: Renewed opportunities through tailored approaches?

Kobayati, A., Haidar, A., & Tsoukas, M. A. (2022) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14637 · Cited by 36 · see citing works

Pancreas and islet morphology in cystic fibrosis: clues to the etiology of cystic fibrosis-related diabetes

Malik, S. S., Padmanabhan, D., & Hull-Meichle, R. L. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1269139 · Cited by 33 · see citing works

Adaptive Effects of Endocrine Hormones on Metabolism of Macronutrients during Fasting and Starvation: A Scoping Review

Karimi, R., Yanovich, A., Elbarbry, F., & Cleven, A. J. (2024) · Metabolites · doi:10.3390/metabo14060336 · Cited by 30 · see citing works

Glucose Metabolism in Burns—What Happens?

Bădoiu, S. C., Miricescu, D., Stănescu-Spînu, I.-I., Totan, A., Badoiu, S. E., Costagliola, M., & Greabu, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22105159 · Cited by 33 · see citing works

Advances in Closed-Loop Insulin Delivery Systems in Patients with Type 1 Diabetes

Dadlani, V., Pinsker, J. E., Dassau, E., & Kudva, Y. C. (2018) · Current Diabetes Reports · doi:10.1007/s11892-018-1051-z · Cited by 30 · see citing works

Postprandial dysmetabolism: Too early or too late?

Pappas, C., Kandaraki, E., Tsirona, S., Kountouras, D., Kassi, G., & Diamanti‐Kandarakis, E. (2016) · HORMONES · doi:10.14310/horm.2002.1697 · Cited by 29 · see citing works

Clinical Presentation and Diagnostic Approach to Hypoglycemia in Adults Without Diabetes Mellitus

Palani, G., Stortz, E., & Moheet, A. (2023) · Endocrine Practice · doi:10.1016/j.eprac.2022.11.010 · Cited by 29 · see citing works

Low doses of dasiglucagon consistently increase plasma glucose levels from hypoglycaemia and euglycaemia in people with type 1 diabetes mellitus

Hövelmann, U., Olsen, M. B., Mouritzen, U., Lamers, D., Kronshage, B., & Heise, T. (2019) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.13562 · Cited by 28 · see citing works

A Fraxinus excelsior L. seeds/fruits extract benefits glucose homeostasis and adiposity related markers in elderly overweight/obese subjects: A longitudinal, randomized, crossover, double-blind, placebo-controlled nutritional intervention study

Zulet, M. Á., Navas‐Carretero, S., y Sánchez, D. L., Abete, I., Flanagan, J., Issaly, N., Fança‐Berthon, P., Bily, A. C., Roller, M., & Martínez, J. A. (2014) · Phytomedicine · doi:10.1016/j.phymed.2014.04.027 · Cited by 27 · see citing works

Sensitization of endocrine organs to anterior pituitary hormones by the autonomic nervous system

Engeland, W. C. (2013) · Handbook of clinical neurology · doi:10.1016/b978-0-444-53491-0.00004-3 · Cited by 23 · see citing works

Disorders of the Endocrine System

Reed, S. M., Bayly, W. M., & Sellon, D. C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-44329-6.00016-4 · Cited by 21 · see citing works

Glucose transporters in the mammalian blood cells

Vrhovac, I., & Breljak, D. (2014) · Hrčak Portal of scientific journals of Croatia (University Computing Centre) · Cited by 20 · see citing works

A closed-loop multi-level model of glucose homeostasis

Uluseker, C., Simoni, G., Marchetti, L., Dauriz, M., Matone, A., & Priami, C. (2018) · PLoS ONE · doi:10.1371/journal.pone.0190627 · Cited by 21 · see citing works

Pharmacokinetics Modeling of Exogenous Glucagon in Type 1 Diabetes Mellitus Patients

Lv, D., Breton, M. D., & Farhy, L. S. (2013) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2013.0150 · Cited by 17 · see citing works

Pancreatic Endocrine Effects of Dopamine Receptors in Human Islet Cells

Zhang, Y., Zheng, R., Meng, X., Wang, L., Liu, L., & Gao, Y. (2015) · Pancreas · doi:10.1097/mpa.0000000000000357 · Cited by 18 · see citing works

Glucagon's Metabolic Action in Health and Disease

Zeigerer, A., Sekar, R., Kleinert, M., Nason, S. R., Habegger, K. M., & Müller, T. D. (2021) · Comprehensive physiology · doi:10.1002/j.2040-4603.2021.tb00161.x · Cited by 18 · see citing works

The Regulation of Metabolic Homeostasis by Incretins and the Metabolic Hormones Produced by Pancreatic Islets

Reed, J., Bain, S. C., & Kanamarlapudi, V. (2024) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s415934 · Cited by 18 · see citing works

Role of islet peptides in beta cell regulation and type 2 diabetes therapy.

Khan, D., Moffet, C., Flatt, P., & Kelly, C. (2018) · Peptides · doi:10.1016/j.peptides.2017.11.014 · Cited by 15 · see citing works

Euglycemic Diabetic Ketoacidosis in Concurrent Very Low-carbohydrate Diet and Sodium-glucose Transporter-2 Inhibitor Use: A Case Report

Earle, M., Ault, B., & Bonney, C. (2020) · Clinical Practice and Cases in Emergency Medicine · doi:10.5811/cpcem.2020.2.45904 · Cited by 14 · see citing works

Increased Serum Levels of Proinflammatory Cytokines Are Accompanied by Fatigue in Military T-6A Texan II Instructor Pilots

Damato, E. G., Fillioe, S. J., Margevicius, S. P., Mayes, R. S., Somogyi, J. E., Vannix, I. S., Abdollahifar, A., Turner, A. M., Ilcus, L. S., & Decker, M. J. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.876750 · Cited by 13 · see citing works

Toward the Existence of a Sympathetic Neuroplasticity Adaptive Mechanism Influencing the Immune Response. A Hypothetical View—Part I

Bottasso, E. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00632 · Cited by 13 · see citing works

Dual‐hormone treatment with insulin and glucagon in patients with type 1 diabetes

Reiband, H. K., Schmidt, S., Ranjan, A. G., Holst, J. J., Madsbad, S., & Nørgaard, K. (2014) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2632 · Cited by 12 · see citing works

Proteins: Structure, properties, and importance

Prasad, B., Shiv, A. K., Bharati, A. C., & Mallick, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91684-4.00003-7 · Cited by 11 · see citing works

Anti-inflammatory and atheroprotective properties of glucagon

Osaka, N., Kushima, H., Mori, Y., Saito, T., Hiromura, M., Terasaki, M., Yashima, H., Ohara, M., Fukui, T., Matsui, T., et al. (2020) · Diabetes and Vascular Disease Research · doi:10.1177/1479164120965183 · Cited by 11 · see citing works

Similar Developmental Patterns of Ghrelin- and Glucagon-Expressing Cells in the Human Pancreas

Vignjević, S., Todorović, V., Damjanovic, S. S., Budeč, M., Ajtić, O. M., Djikić, D., Drndarević, N., Mićić, M., Mišković-Krivokapić, J., Djuricic, S. M., et al. (2012) · Cells Tissues Organs · doi:10.1159/000335469 · Cited by 10 · see citing works

Classical and non-classical islet peptides in the control of β-cell function

Khan, D., Moffett, R. C., Flatt, P. R., & Tarasov, A. I. (2021) · Peptides · doi:10.1016/j.peptides.2021.170715 · Cited by 10 · see citing works

Glycaemic control in end-of-life care

Lindskog, M., Kärvestedt, L., & Fürst, C. J. (2014) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0000000000000095 · Cited by 10 · see citing works

Streptozotocin-induced diabetes affects in rat liver citrate carrier gene expression by transcriptional and posttranscriptional mechanisms

Damiano, F., Mercuri, E., Stanca, E., Gnoni, G. V., & Siculella, L. (2011) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2011.07.011 · Cited by 10 · see citing works

New Developments in Glucagon Treatment for Hypoglycemia

Hayward, L., & Wilson, L. M. (2022) · Drugs · doi:10.1007/s40265-022-01754-8 · Cited by 10 · see citing works

Possible Contribution of Taurine to Distorted Glucagon Secretion in Intra-Islet Insulin Deficiency: A Metabolome Analysis Using a Novel α-Cell Model of Insulin-Deficient Diabetes

Bessho, M., Murase‐Mishiba, Y., Imagawa, A., Terasaki, J., & Hanafusa, T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113254 · Cited by 9 · see citing works

Glucagon, insulin, adrenocorticotropic hormone, and cortisol in response to carbohydrates and fasting in healthy neonatal foals

Kinsella, H. M., Hostnik, L. D., Rings, L. M., Swink, J. M., Burns, T. A., & Toribio, R. E. (2021) · Journal of Veterinary Internal Medicine · doi:10.1111/jvim.16024 · Cited by 8 · see citing works

Glucagonotropic and glucagonostatic effects of KATP channel closure and potassium depolarization.

Früh, E., Elgert, C., Eggert, F., Scherneck, S., & Rustenbeck, I. (2020) · Endocrinology · doi:10.1210/endocr/bqaa136 · Cited by 10 · see citing works

Toward the Existence of a Sympathetic Neuroplasticity Adaptive Mechanism Influencing the Immune Response. A Hypothetical View—Part II

Bottasso, E. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00633 · Cited by 8 · see citing works

Metabolic Regulation of Hormone Secretion in Beta-Cells and Alpha-Cells of Female Mice: Fundamental Differences

Brüning, D., Morsi, M., Früh, E., Scherneck, S., & Rustenbeck, I. (2022) · Endocrinology · doi:10.1210/endocr/bqac125 · Cited by 8 · see citing works

Biomimetic Cell Membrane Layers for the Detection of Insulin and Glucagon

Nandhakumar, P., Sun, L., Li, Z., Cheung, C., Nguyen, L., Ding, S., Gao, W., Zhang, L., & Wang, J. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.4c05347 · Cited by 7 · see citing works

Effect of feeding brown rice instead of corn on lactation performance and blood metabolites in periparturient dairy cows

Miyaji, M., Haga, S., Matsuyama, H., & Hosoda, K. (2016) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2016.06.023 · Cited by 5 · see citing works

A Survey and Guide to the Development of Fatty Acid‐derivatized Peptide Therapeutics

Jacobsen, M. T., Poulsen, C., Kopp, K. L., Olsen, J., & Cox, N. (2025) · Peptide Science · doi:10.1002/9781119824701.ch07 · Cited by 5 · see citing works

Evaluation of Trace Elements Levels and Construction of Auxiliary Prediction Model in Patients with Diabetes Ketoacidosis in Type 1 Diabetes

Chai, J., Sun, Z., Zhou, Q., & Xu, J. (2023) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s425156 · Cited by 4 · see citing works

Features of the alpha-cell population organization in pancreas of spontaneously hypertensive rats (SHR)

Аbramova, Т. V., & Kolesnyk, Y. M. (2017) · Pathologia · doi:10.14739/2310-1237.2017.2.109249 · Cited by 4 · see citing works

Effects of CBD (Cannabidiol) on the haematological parameters of Nile tilapia ( Oreochromis niloticus , Linnaeus) under acute stress in vivo

Mortuza, A., Mason, L., & Mustafa, A. (2021) · Aquaculture Research · doi:10.1111/are.15407 · Cited by 4 · see citing works

Discovery of novel OXM-based glucagon-like peptide 1 (GLP-1)/glucagon receptor dual agonists

Zhang, X., Cai, Y., Yao, Z., Chi, H., Li, Y., Shi, J., Zhou, Z., & Sun, L. (2023) · Peptides · doi:10.1016/j.peptides.2023.170948 · Cited by 4 · see citing works

Falla autonómica asociada a hipoglucemia

Houssay, S., Recalde, M., Rey, M. G., García, C., Urdaneta, R., Huber, F., Flores, C. L. U., Domínguez, C., & Nader, E. (2021) · Revista de la Sociedad Argentina de Diabetes · doi:10.47196/diab.v55i2.473 · Cited by 4 · see citing works

NEURAL CONTROL OF PANCREATIC PEPTIDE HORMONE SECRETION.

Verberne, A., & Mussa, B. M. (2022) · Peptides · doi:10.1016/j.peptides.2022.170768 · Cited by 4 · see citing works

Diabetic Ketoacidosis in adults: Part 1. Pathogenesis and diagnosis

Azkoul, A., Sim, S. Y., & Lawrence, V. (2022) · South Sudan Medical Journal · doi:10.4314/ssmj.v15i2.6 · Cited by 4 · see citing works

Glucose-Lowering Agents Developed in the Last Two Decades and Their Perioperative Implications

Goudra, B., Merli, G. J., & Green, M. S. (2024) · Pharmaceuticals · doi:10.3390/ph18010004 · Cited by 3 · see citing works

Effects of CBD (Cannabidiol) on the physiology of Nile tilapia (Oreochromisn niloticus) as a chronic stress mitigating agent In-vivo

Mortuza, A., Fahim, N. F., Ahmed, M., & Mustafa, A. (2023) · PLoS ONE · doi:10.1371/journal.pone.0290835 · Cited by 3 · see citing works

A Guide to the Postmortem Investigation of Starvation in Adults

Garland, J., & Irvine, R. (2022) · American Journal of Forensic Medicine & Pathology · doi:10.1097/paf.0000000000000763 · Cited by 3 · see citing works

Modulation of acute stress and immune response in tilapia, Oreochromis niloticus, using longevity spinach, Gynura procumbens extract, as nutraceuticals

Mumu, S. K., & Mustafa, A. (2022) · Journal of Immunoassay and Immunochemistry · doi:10.1080/15321819.2022.2080558 · Cited by 3 · see citing works

Clinical efficacy and safety of dasiglucagon in severe hypoglycemia associated with patients of type 1 diabetes mellitus: a systematic review and meta-analysis

Dholariya, S. J., Parchwani, D. N., Dutta, S., & Singh, R. (2022) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2023.2138343 · Cited by 2 · see citing works

Intra-pancreatic fat is associated with high circulating glucagon and GLP-1 concentrations following whey protein ingestion in overweight women with impaired fasting glucose: A randomised controlled trial

Lim, J. J., Sequeira, I. R., Yip, W. C. Y., Lu, L. W., Miles-Chan, J. L., & Poppitt, S. D. (2023) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2023.111084 · Cited by 2 · see citing works

Incretins for management of obesity and obstructive sleep apnea

Hu, X., Yee, B. J., Phillips, C. L., Chapman, J. L., & Grunstein, R. R. (2025) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2025.2513516 · Cited by 2 · see citing works

In insulin-treated type 1 diabetes, canagliflozin increased diabetic ketoacidosis

Sfeir, J. G., & Montori, V. M. (2016) · Annals of Internal Medicine · doi:10.7326/acpjc-2016-165-2-002 · Cited by 2 · see citing works

Substraatgebruik bij paarden tijdens inspanning - een vergelijking tussen de ‘gevaste’ en postprandiale status

Robyn, J., Plancke, L., Boshuizen, B., meeûs, C. D., Bruijn, M. D., & Delesalle, C. J. G. (2017) · Vlaams Diergeneeskundig Tijdschrift · doi:10.21825/vdt.v86i5.16166 · Cited by 2 · see citing works

G-protein tonic inhibition of calcium channels in pancreatic β-cells

Quiroz‐Acosta, T., Bermeo, K., Arenas, I., & Garcı́a, D. E. (2023) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00447.2022 · Cited by 2 · see citing works

Hormones and Growth Factors Used Therapeutically

Walsh, G. (2015) · doi:10.1002/9781119117599.ch8 · Cited by 2 · see citing works

Augmented glucagon-induced gluconeogenesis in primary hepatocytes from Otsuka Long-Evans Tokushima Fatty rats

Deguchi, M., Hosoda, A., Fukumura, T., Saeki, S., & Kim, D.-H. (2025) · Bioscience Biotechnology and Biochemistry · doi:10.1093/bbb/zbaf133 · Cited by 1 · see citing works

Pomegranate peel extract nanoparticles enhance insulin production and antioxidant activity of diabetic rats

Sayed, H. Y. I. A., Abdelglil, M. I., Mohamed, H. R. H., Baiomy, A. A. A., & Mohamed, A. S. (2026) · Tissue and Cell · doi:10.1016/j.tice.2026.103423 · Cited by 1 · see citing works

Mitochondrial NCLX couples glucagon- and PDE2A-Dependent signals to regulate hepatic lipid metabolism

Assali, E. A., Taha, M., Salhab, A., Amer, J., Krishnan, K. C., Kostić, M., Veliova, M., Brownstein, A. J., Shirihai, O. S., Safadi, R., et al. (2026) · Molecular Metabolism · doi:10.1016/j.molmet.2026.102433 · Cited by 1 · see citing works

Role of glucagon in treating diabetes: Evidence and concepts (胰高血糖素在糖尿病治疗中的作用：证据与概念)

Bloomgarden, Z. T. (2013) · Journal of Diabetes · doi:10.1111/1753-0407.12107 · Cited by 1 · see citing works

Severe Trichotillomania: An Unusual Trigger of Recurrent Diabetic Ketoacidosis

Check, L., Figueroa, G. E., Galindo, L., PHAM, J., & Sherertz, R. J. (2022) · Cureus · doi:10.7759/cureus.21384 · Cited by 1 · see citing works

Diabetes in the Critically Ill Patient: DKA, HHS, and Beyond

Singh, B., Chlebek, S., & Krikorian, A. (2023) · Contemporary Endocrinology · doi:10.1007/978-3-031-44648-1_5 · Cited by 1 · see citing works

CaMKKbeta/AMPK Negatively Regulates Adiposity

Peng, I. (2011) · eScholarship (California Digital Library)

Examining the Role of Endoplasmic Reticulum Stress in Pancreatic Beta-cell Biology

Teodoro, T. (2012) · TSpace (University of Toronto)

The Physiological Glucagon Receptor in Rat Heart

Agostinucci, K. J. (2017) · doi:10.23860/thesis-agostinucci-kevin-2017

Sympathetic Voltage-Independent Regulation of Voltage- Gated Calcium Channels in Pancreatic β-Cells

Garcı́a, D. E. (2018) · Journal of Endocrinology and Diabetes · doi:10.15226/2374-6890/5/1/00194

Caracterización química de cucurbita ficifolia Bouché y su efecto hipoglucémico mediado por almacenamiento del glucógeno hepático

García‐González, J. (2017) · doi:10.24275/uami.nz805z690

A dynamical model and bifurcation analysis for glucagon and glucose regulatory system

Mohabati, F., Molaei, M. R., & Waezizadeh, T. (2019) · Journal of Information and Optimization Sciences · doi:10.1080/02522667.2019.1630937

Dasiglucagon for treating severe hypoglycemia in patients with diabetes

Ju, Y., Zhang, D., & Yang, J. (2022) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2022.2103537

Miért nem fenyegeti a ketoacidosis a teljes hasnyálmirigy-eltávolításon átesett betegeket?

Kaszoni-Bokor, G. L., Kis, J. T., Szemán, A., Kiss, K. A., Polyák, A., Czégeni, A., Hosszúfalusi, N., Schandl, L., & Winkler, G. (2025) · Orvosi Hetilap · doi:10.1556/650.2025.33407

Distinct and complementary metabolic effects of GLP-1 and glucagon receptor agonism in diet-induced obese mice

Winther‐Sørensen, M., Rasmussen, C. B., Trammell, S. A. J., Hansen, C., Vyberg, M., Serizawa, R., Richter, E. A., Grevengoed, T. J., Gluud, L. L., Kuhre, R. E., et al. (2025) · Peptides · doi:10.1016/j.peptides.2025.171462 · Cited by 2 · see citing works

Control Systems in the Living World

Cabej, N. R. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-401667-5.00001-8

Autonomic mediation of glucagon secretion during hypoglycemia: implications for impaired alpha-cell responses in type 1 diabetes.

Taborsky, G. J., Åhrén, B., & Havel, P. J. (1998) · Diabetes · doi:10.2337/diabetes.47.7.995 · Cited by 210 · see citing works

Physiological and Pathophysiological Control of Glucagon Secretion by Pancreatic α-Cells

Gilon, P., Cheng, R., Lai, B. K., Chae, H., & Gómez-Ruiz, A. (2014) · Springer eBooks · doi:10.1007/978-94-007-6686-0_37 · Cited by 3 · see citing works

Minireview: Glucagon in the Pathogenesis of Hypoglycemia and Hyperglycemia in Diabetes

Cryer, P. E. (2012) · Endocrinology · doi:10.1210/en.2011-1499 · Cited by 242 · see citing works

Glucose control of glucagon secretion—‘There’s a brand-new gimmick every year’

Gylfe, E. (2016) · Upsala Journal of Medical Sciences · doi:10.3109/03009734.2016.1154905 · Cited by 71 · see citing works

The Role of α-Cells in Islet Function and Glucose Homeostasis in Health and Type 2 Diabetes

Gilon, P. (2020) · Journal of Molecular Biology · doi:10.1016/j.jmb.2020.01.004 · Cited by 90 · see citing works