The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Effects of blackberries on motor and cognitive function in aged rats
Abstract
The polyphenolics in fruits and vegetables, when fed to rats from 19-21 months of age, have been shown to retard and even reverse age-related decrements in motor and cognitive performance. These effects may be the result of the polyphenols increasing antioxidant and/or anti-inflammatory levels, or by direct effects on signaling, in the brain. Increased dietary intake of berry fruit, in particular, has a positive and profound impact on human health, performance, and disease. Thus, the present study examined a 2% blackberry-supplemented diet for its effectiveness in reversing age-related deficits in behavioral and neuronal function when fed to aged (19-month-old) Fischer 344 rats for 8 weeks. The results showed that the blackberry diet improved motor performance on three tasks which rely on balance and co-ordination: the accelerating rotarod, wire suspension, and the small plank walk. Results for the Morris water maze showed that the blackberry-fed rats had significantly greater working, or short-term, memory performance than the control rats. These data support our previous investigations in which we have seen improved motor and cognitive performance in aged rats after supplementation with other berry fruits.
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Mattson, M. P. (2008) · Ageing Research Reviews · doi:10.1016/j.arr.2007.08.007 · Cited by 1,253
Seeram, N. P., Adams, L. S., Zhang, Y., Lee, R., Sand, D., Scheuller, H. S., & Heber, D. (2006) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf061750g · Cited by 770
Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats
Bickford, P. C., Gould, T., Briederick, L., Chadman, K., Pollock, A., Young, D., Shukitt-Hale, B., & Joseph, J. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02280-0 · Cited by 298
Self-citationViewpoint: Mechanisms of Action and Therapeutic Potential of Neurohormetic Phytochemicals
Mattson, M. P., Son, T. G., & Camandola, S. (2007) · Dose-Response · doi:10.2203/dose-response.07-004.mattson · Cited by 137
Cited by
Del Rio, D., Rodriguez-Mateos, A., Spencer, J. P. E., Tognolini, M., Borges, G., & Crozier, A. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4581 · Cited by 2,601
MIND diet associated with reduced incidence of Alzheimer's disease
Morris, M. C., Tangney, C. C., Wang, Y., Sacks, F. M., Bennett, D. A., & Aggarwal, N. T. (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2014.11.009 · Cited by 1,162
Mattioli, R., Francioso, A., Mosca, L., & Silva, P. (2020) · Molecules · doi:10.3390/molecules25173809 · Cited by 1,042
Nutritional value, bioactive compounds and health benefits of lettuce (Lactuca sativa L.)
Kim, M. J., Moon, Y., Tou, J. C., Mou, B., & Waterland, N. L. (2016) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2016.03.004 · Cited by 690
Williams, R. J., & Spencer, J. P. E. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.09.010 · Cited by 448
Metadata
- Authors
- Shukitt-Hale, B., Cheng, V., & Joseph, J. A.
- Venue
- Nutritional Neuroscience
- Publisher
- Informa UK Limited
- Published
- 2009-06
- Volume
- 12
- Issue
- 3
- Pages
- 135-140
- ISSN
- 1028-415X (ISSN-L)
- 1476-8305
- OpenAlex
- W2061907170
- Cited by
- 166
- References
- 4
- FWCI
- 7.66
- Type
- journal article
- Language
- en
- Open access
- closed
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