TAK1 targeting by glucocorticoids determines JNK and IκB regulation in Toll-like receptor–stimulated macrophages

Toll-like receptor signalling

Akira, S., & Takeda, K. (2004) · Nature reviews. Immunology · doi:10.1038/nri1391 · Cited by 8,312 · see citing works

Toll-Like Receptors

Takeda, K., Kaisho, T., & Akira, S. (2003) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141126 · Cited by 6,143 · see citing works

Phosphorylation meets ubiquitination: the control of NF-κB activity

Karin, M., & Ben-Neriah, Y. (2000) · Annual Review of Immunology · doi:10.1146/annurev.immunol.18.1.621 · Cited by 4,766 · see citing works

Toll-like receptors and innate immunity

Medzhitov, R. (2001) · Nature Reviews Immunology · doi:10.1038/35100529 · Cited by 4,308 · see citing works

Toll-like receptors in innate immunity

Takeda, K. (2004) · International Immunology · doi:10.1093/intimm/dxh186 · Cited by 3,328 · see citing works

Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs

Rhen, T., & Cidlowski, J. A. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050541 · Cited by 3,149 · see citing works

Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis

Auphan, N., DiDonato, J. A., Rosette, C., Helmberg, A., & Karin, M. (1995) · Science · doi:10.1126/science.270.5234.286 · Cited by 2,390 · see citing works

Conditional gene targeting in macrophages and granulocytes using LysMcre mice

Clausen, B. E., Burkhardt, C., Reith, W., Renkawitz, R., & Förster, I. (1999) · Transgenic Research · doi:10.1023/a:1008942828960 · Cited by 2,143 · see citing works

TLR signaling

Kawai, T., & Akira, S. (2006) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401850 · Cited by 1,817 · see citing works

Role of Transcriptional Activation of IκBα in Mediation of Immunosuppression by Glucocorticoids

Scheinman, R. I., Cogswell, P. C., Lofquist, A. K., & Baldwin, A. S. (1995) · Science · doi:10.1126/science.270.5234.283 · Cited by 1,676 · see citing works

MAP Kinases in the Immune Response

Dong, C., Davis, R. J., & Flavell, R. A. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.091301.131133 · Cited by 1,660 · see citing works

Negative regulation of Toll-like receptor-mediated immune responses

Liew, F. Y., Xu, D., Brint, E. K., & O'Neill, L. A. J. (2005) · Nature Reviews Immunology · doi:10.1038/nri1630 · Cited by 1,509 · see citing works

Cooperation of Toll-like receptor signals in innate immune defence

Trinchieri, G., & Sher, A. (2007) · Nature reviews. Immunology · doi:10.1038/nri2038 · Cited by 1,357 · see citing works

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

Hoebe, K. H. N., Du, X., Georgel, P., Janssen, E. M., Tabeta, K., Kim, S. O., Goode, J., Lin, P., Mann, N., Mudd, S., et al. (2003) · Nature · doi:10.1038/nature01889 · Cited by 1,232 · see citing works

TRAM is specifically involved in the Toll-like receptor 4–mediated MyD88-independent signaling pathway

Yamamoto, M., Sato, S., Hemmi, H., Uematsu, S., Hoshino, K., Kaisho, T., Takeuchi, O., Takeda, K., & Akira, S. (2003) · Nature Immunology · doi:10.1038/ni986 · Cited by 1,052 · see citing works

Toll-like receptor function and signaling

Kaisho, T., & Akira, S. (2006) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2006.02.023 · Cited by 893 · see citing works

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivoPreprint

Shim, J., Xiao, C., Paschal, A. E., Bailey, S. T., Rao, P., Hayden, M. S., Lee, K., Bussey, C., Steckel, M., Tanaka, N., et al. (2005) · Genes & Development · doi:10.1101/gad.1360605 · Cited by 735 · see citing works

Molecular determinants of crosstalk between nuclear receptors and toll-like receptors

Ogawa, S., Lozach, J., Benner, C., Pascual, G., Tangirala, R. K., Westin, S., Hoffmann, A., Subramaniam, S., David, M., Rosenfeld, M. G., et al. (2005) · Cell · doi:10.1016/j.cell.2005.06.029 · Cited by 647 · see citing works

How Toll-like receptors signal: what we know and what we don’t know

O'Neill, L. A. J. (2005) · Current Opinion in Immunology · doi:10.1016/j.coi.2005.11.012 · Cited by 614 · see citing works

Direct activation of protein kinases by unanchored polyubiquitin chains

Xia, Z.-P., Sun, L., Chen, X., Pineda, G., Jiang, X., Adhikari, A., Zeng, W., & Chen, Z. J. (2009) · Nature · doi:10.1038/nature08247 · Cited by 570 · see citing works

Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses

Chi, H., Barry, S. P., Flach, R. J. R., Wu, J. J., Jones, E. A., Bennett, A. M., & Flavell, R. A. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510965103 · Cited by 569 · see citing works

Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

Mansell, A. S., Smith, R., Doyle, S., Gray, P., Fenner, J. E., Crack, P. J., Nicholson, S. E., Hilton, D. J., O'Neill, L. A. J., & Hertzog, P. J. (2006) · Nature Immunology · doi:10.1038/ni1299 · Cited by 513 · see citing works

Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IκBζ

Yamamoto, M., Yamazaki, S., Uematsu, S., Sato, S., Hemmi, H., Hoshino, K., Kaisho, T., Kuwata, H., Takeuchi, O., Takeshige, K., et al. (2004) · Nature · doi:10.1038/nature02738 · Cited by 498 · see citing works

Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1

Abraham, S. M., Lawrence, T., Kleiman, A., Warden, P., Medghalchi, M., Tuckermann, J., Saklatvala, J., & Clark, A. R. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20060336 · Cited by 430 · see citing works

Dendritic cell–induced autoimmune heart failure requires cooperation between adaptive and innate immunity

Eriksson, U., Ricci, R., Hunziker, L., Kurrer, M. O., Oudit, G. Y., Watts, T. H., Sonderegger, I., Bachmaier, K., Kopf, M., & Penninger, J. M. (2003) · Nature Medicine · doi:10.1038/nm960 · Cited by 405 · see citing works

MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock

Zhao, Q., Wang, X., Nelin, L. D., Yao, Y., Matta, R., Manson, M. E., Baliga, R. S., Meng, X., Smith, C. V., Bauer, J. A., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20051794 · Cited by 370 · see citing works

Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor κB

Ayroldi, E., Migliorati, G., Bruscoli, S., Marchetti, C., Zollo, O., Cannarile, L., D'Adamio, F., & Riccardi, C. (2001) · Blood · doi:10.1182/blood.v98.3.743 · Cited by 318 · see citing works

Inhibition of AP-1 by the Glucocorticoid-inducible Protein GILZ

Mittelstadt, P. R., & Ashwell, J. D. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101522200 · Cited by 301 · see citing works

Macrophage glucocorticoid receptors regulate Toll-like receptor 4-mediated inflammatory responses by selective inhibition of p38 MAP kinase

Bhattacharyya, S., Brown, D. E., Brewer, J. A., Vogt, S. K., & Muglia, L. J. (2007) · Blood · doi:10.1182/blood-2006-10-048215 · Cited by 249 · see citing works

Inhaled Corticosteroids Are Not Beneficial in Chronic Obstructive Pulmonary Disease

Barnes, P. J. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.2.16125_2 · Cited by 186 · see citing works

CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages

Liu, X., Yao, M., Li, N., Wang, C., Zheng, Y., & Cao, X. (2008) · Blood · doi:10.1182/blood-2008-03-144022 · Cited by 180 · see citing works

Corticosteroid-insensitive asthma: molecular mechanisms

Adcock, I. M., & Lane, S. (2003) · Journal of Endocrinology · doi:10.1677/joe.0.1780347 · Cited by 179 · see citing works

Cooperative control of Drosophila immune responses by the JNK and NF‐κB signaling pathways

Delaney, J. R., Stöven, S., Uvell, H., Anderson, K. V., Engström, Y., & Mlodzik, M. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601182 · Cited by 176 · see citing works

Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IκB kinase activity

Bhattacharyya, S., Sen, P., Wallet, M. A., Long, B., Baldwin, A. S., & Tisch, R. (2004) · Blood · doi:10.1182/blood-2003-12-4302 · Cited by 173 · see citing works

TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide

Lee, J., Arbibe, L., & Ulevitch, R. J. (2000) · Journal of Leukocyte Biology · doi:10.1189/jlb.68.6.909 · Cited by 173 · see citing works

Glucocorticoid receptor action in beneficial and side effects of steroid therapy: lessons from conditional knockout mice

Kleiman, A., & Tuckermann, J. P. (2007) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2007.05.009 · Cited by 165 · see citing works

Glutathione Supplementation Potentiates Hypoxic Apoptosis by S-Glutathionylation of p65-NFκB

Qanungo, S., Starke, D. W., Pai, H. V., Mieyal, J. J., & Nieminen, A. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m610934200 · Cited by 160 · see citing works

Essential role of TAK1 in thymocyte development and activation

Liu, H.-H., Xie, M., Schneider, M. D., & Chen, Z. J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603089103 · Cited by 155 · see citing works

T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation

Brewer, J. A., Khor, B., Vogt, S. K., Muglia, L. M., Fujiwara, H., Haegele, K. E., Sleckman, B. P., & Muglia, L. J. (2003) · Nature Medicine · doi:10.1038/nm895 · Cited by 149 · see citing works

Toll–like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes

Kolek, M. J., Carlquist, J. F., Muhlestein, J. B., Whiting, B. M., Horne, B. D., Bair, T. L., & Anderson, J. L. (2004) · American Heart Journal · doi:10.1016/j.ahj.2004.05.049 · Cited by 137 · see citing works

Glucocorticoids and the innate immune system: crosstalk with the toll-like receptor signaling network

Chinenov, Y., & Rogatsky, I. (2007) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2007.04.014 · Cited by 133 · see citing works

TLR Activation Synergizes with Kilham Rat Virus Infection to Induce Diabetes in BBDR Rats

Zipris, D., Lien, E., Xie, J. X., Greiner, D. L., Mordes, J. P., & Rossini, A. A. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.1.131 · Cited by 129 · see citing works

Regulation of tumor necrosis factor receptor-1 and the IKK-NF-κB pathway by LDL receptor–related protein explains the antiinflammatory activity of this receptor

Gaultier, A., Arandjelovic, S., Niessen, S., Overton, C. D., Linton, M. F., Fazio, S., Campana, W. M., Cravatt, B. F., & Gonias, S. L. (2008) · Blood · doi:10.1182/blood-2007-12-127613 · Cited by 104 · see citing works

Evidence for the ancient origin of the NF-κB/IκB cascade: Its archaic role in pathogen infection and immunity

Wang, X. W., Tan, N. S., Ho, B., & Ding, J. L. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507044103 · Cited by 94 · see citing works

TGFβ Activated Kinase-1: New Insights into the Diverse Roles of TAK1 in Development and Immunity

Delaney, J. R., & Mlodzik, M. (2006) · Cell Cycle · doi:10.4161/cc.5.24.3558 · Cited by 91 · see citing works

A comparative analysis of cytokine responses, cell surface marker expression and MAPKs in DCs matured with LPS compared with a panel of TLR ligands

Dowling, D. J., Hamilton, C. M., & O’Neill, S. M. (2008) · Cytokine · doi:10.1016/j.cyto.2007.11.020 · Cited by 74 · see citing works

Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex

Mendoza, H., Campbell, D. G., Burness, K. A., Hastie, C. J., Ronkina, N., Shim, J., Arthur, J. S. C., Davis, R. J., Gaestel, M., Johnson, G. L., et al. (2008) · Biochemical Journal · doi:10.1042/bj20071149 · Cited by 69 · see citing works

Immunomodulatory Activities of Glucocorticoids: Insights from Transgenesis and Gene Targeting

Reichardt, H. M. (2004) · Current Pharmaceutical Design · doi:10.2174/1381612043383575 · Cited by 33 · see citing works

Analysis of toll-like receptor-dependent production of proinflammatory cytokines in vitro by human peripheral blood mononuclears of donors and patients with primary immunodeficiency

Ковальчук, Л. В., Хорева, М. В., Varivoda, A. S., Pashchenko, O. E., Грачева, Л. А., Быкова, Л. П., Вадимовна, К. И., & Бологов, А. А. (2007) · Bulletin of Experimental Biology and Medicine · doi:10.1007/s10517-007-0255-z · Cited by 2 · see citing works

Pathogenesis and Pathophysiology of Pneumococcal Meningitis

Mook-Kanamori, B. B., Geldhoff, M., van der Poll, T., & van de Beek, D. (2011) · Clinical Microbiology Reviews · doi:10.1128/cmr.00008-11 · Cited by 492 · see citing works

The HPA – Immune Axis and the Immunomodulatory Actions of Glucocorticoids in the Brain

Bellavance, M.-A., & Rivest, S. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00136 · Cited by 419 · see citing works

YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis

Zhou, X., Li, W., Wang, S., Zhang, P., Wang, Q., Xiao, J., Zhang, C., Zheng, X. M., Xu, X., Xue, S., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.03.028 · Cited by 376 · see citing works

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer’s disease

Seo, E.-J., Fischer, N., & Efferth, T. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2017.11.030 · Cited by 265 · see citing works

Inflammation in Parkinson’s disease: role of glucocorticoids

Herrero, M.-T., Estrada, C., Maatouk, L., & Vyas, S. (2015) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2015.00032 · Cited by 175 · see citing works

Regulation of Toll‐like receptor signaling pathways in innate immune responses

Qian, C., & Cao, X. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06786.x · Cited by 168 · see citing works

The potential role of neuroinflammation and transcription factors in Parkinson disease

Tiwari, P. C., & Pal, R. (2017) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2017.19.1/rpal · Cited by 167 · see citing works

Evading innate immunity in nonviral mRNA delivery: don't shoot the messenger.

Devoldere, J., Dewitte, H., De Smedt, S. C., & Remaut, K. (2016) · Drug Discovery Today · doi:10.1016/j.drudis.2015.07.009 · Cited by 112 · see citing works

Pathophysiology of neonatal acute bacterial meningitis

Barichello, T., Fagundes, G. D., Generoso, J. S., Galvão-Elias, S., Simões, L. R., & Teixeira, A. L. (2013) · Journal of Medical Microbiology · doi:10.1099/jmm.0.059840-0 · Cited by 109 · see citing works

Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation

Bhattacharyya, S., Zhao, Y., Kay, T. W. H., & Muglia, L. J. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1017296108 · Cited by 93 · see citing works

TRP Channels Role in Pain Associated With Neurodegenerative Diseases

Duitama, M., Vargas-López, V., Casas, Z., Albarracin, S., Sutachan, J., & Torres, Y. P. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00782 · Cited by 77 · see citing works

Anti-inflammatory and Protective Properties of Daphnetin in Endotoxin-Induced Lung Injury

Yu, W., Lü, Z., Zhang, H., Kang, Y., Mao, Y., Wang, H., Ge, W., & Shi, L. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf503667v · Cited by 74 · see citing works

Role of neuroinflammation and latent transcription factors in pathogenesis of Parkinson’s disease

Pal, R., Tiwari, P. C., Nath, R., & Pant, K. K. (2016) · Neurological Research · doi:10.1080/01616412.2016.1249997 · Cited by 72 · see citing works

Reservoir of Fibroblasts Promotes Recovery From Limb Ischemia

Meng, S., Lv, J., Chanda, P. K., Owusu, I., Chen, K., & Cooke, J. P. (2020) · Circulation · doi:10.1161/circulationaha.120.046872 · Cited by 62 · see citing works

The neuroendocrine control of the innate immune system in health and brain diseases

Bellavance, M., & Rivest, S. (2012) · Immunological Reviews · doi:10.1111/j.1600-065x.2012.01129.x · Cited by 60 · see citing works

The glucocorticoid receptor in inflammatory processes: transrepression is not enough

Hübner, S., Dejager, L., Libert, C., & Tuckermann, J. P. (2015) · Biological Chemistry · doi:10.1515/hsz-2015-0106 · Cited by 57 · see citing works

Kinase Inhibition as Treatment for Acute and Chronic Graft-Versus-Host Disease

Braun, L. M., & Zeiser, R. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.760199 · Cited by 47 · see citing works

Combined Stimulation of Toll-Like Receptor 5 and NOD1 Strongly Potentiates Activity of NF-κB, Resulting in Enhanced Innate Immune Reactions and Resistance to Salmonella enterica Serovar Typhimurium Infection

Ильдарович, Т. А., Gitlin, I. I., Shcheblyakov, D. V., Artemicheva, N. M., Burdelya, L. G., Шмаров, М. М., Naroditsky, B. S., Gudkov, A. V., Al, G., & Logunov, D. Y. (2013) · Infection and Immunity · doi:10.1128/iai.00525-13 · Cited by 43 · see citing works

Corticosteroids shift the Toll-like receptor response pattern of primary-isolated murine liver cells from an inflammatory to an anti-inflammatory state

Broering, R., Montag, M., Jiang, M., Lu, M., Sowa, J., Kleinehr, K., Gerken, G., & Schlaak, J. (2011) · International Immunology · doi:10.1093/intimm/dxr048 · Cited by 41 · see citing works

Pluripotent Stem Cell Model of Nakajo-Nishimura Syndrome Untangles Proinflammatory Pathways Mediated by Oxidative Stress

Honda‐Ozaki, F., Terashima, M., Niwa, A., Saiki, N., Kawasaki, Y., Ito, H., Hotta, A., Nagahashi, A., Igura, K., Asaka, I., et al. (2018) · Stem Cell Reports · doi:10.1016/j.stemcr.2018.04.004 · Cited by 36 · see citing works

MAPK Kinase 3 Potentiates Chlamydia HSP60-Induced Inflammatory Response through Distinct Activation of NF-κB

Kang, Y., Wang, F., Lü, Z., Ying, H., Zhang, H., Ding, W., Wang, C., & Shi, L. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300481 · Cited by 34 · see citing works

Glucocorticoids inhibit dendritic cell maturation induced by Toll-like receptor 7 and Toll-like receptor 8

Larangé, A., Antonios, D., Pallardy, M. J., & Kerdine‐Römer, S. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.1110615 · Cited by 29 · see citing works

Immune-enhancing effects of anionic macromolecules extracted from Codium fragile on cyclophosphamide-treated mice

Monmai, C., You, S., & Park, W. J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0211570 · Cited by 25 · see citing works

Inhibition of IRAK1 Ubiquitination Determines Glucocorticoid Sensitivity for TLR9-Induced Inflammation in Macrophages

Kong, F., Liu, Z., Jain, V. G., Shima, K., Suzuki, T., Muglia, L. J., Starczynowski, D. T., Pasare, C., & Bhattacharyya, S. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700443 · Cited by 25 · see citing works

A novel triptolide derivative ZT01 exerts anti-inflammatory effects by targeting TAK1 to prevent macrophage polarization into pro-inflammatory phenotype

Fu, J., Zang, Y., Zhou, Y. J., Chen, C., Shao, S., Hu, M. S., Shi, G., Wu, L., Zhang, D., & Zhang, T. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110084 · Cited by 23 · see citing works

Toll‐like receptor‐mediated immune response inhibits prion propagation

Kang, S., Kim, C., Cortez, L. M., Garza, M. C., Yang, J., Wille, H., Sim, V. L., Westaway, D. A., McKenzie, D. I., & Aiken, J. M. (2016) · Glia · doi:10.1002/glia.22973 · Cited by 22 · see citing works

Anti-inflammatory action of 2-carbomethoxy-2,3-epoxy-3-prenyl-1,4-naphthoquinone (CMEP-NQ) suppresses both the MyD88-dependent and TRIF-dependent pathways of TLR4 signaling in LPS-stimulated RAW264.7 cells

Woo, H. J., Jun, D. Y., Lee, J. Y., Park, H. S., Woo, M. H., Park, S. J., Kim, S. C., Yang, C. H., & Kim, Y. H. (2017) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2017.04.029 · Cited by 21 · see citing works

Prunus yedoensis Bark Inhibits Lipopolysaccharide-Induced Inflammatory Cytokine Synthesis by IκBα Degradation and MAPK Activation in Macrophages

Yun, J., Im, S.-B., Roh, M.-K., Park, S., Kwon, H.-A., Lee, J.-Y., Choi, H.-Y., Ham, I., Kim, Y. B., Lee, J.-M., et al. (2014) · Journal of Medicinal Food · doi:10.1089/jmf.2013.2825 · Cited by 21 · see citing works

NFκB- and MAP-Kinase Signaling Contribute to the Activation of Murine Myeloid Dendritic Cells by a Flagellin A: Allergen Fusion Protein

Moeller, T., Wolfheimer, S., Goretzki, A., Scheurer, S., & Schülke, S. (2019) · Cells · doi:10.3390/cells8040355 · Cited by 20 · see citing works

The -144C/A Polymorphism in the Promoter of HSP90beta Is Associated with Multiple Organ Dysfunction Scores

Zhao, Y., Tao, L., Jiang, D., Chen, X., Li, P., Ning, Y., Xiong, R., Liu, P., Peng, Y., & Zhou, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058646 · Cited by 17 · see citing works

Immuno-enhancement effect of polysaccharide extracted from Stichopus japonicus on cyclophosphamide-induced immunosuppression mice

Monmai, C., Park, S. H., You, S., & Park, W. J. (2017) · Food Science and Biotechnology · doi:10.1007/s10068-017-0248-2 · Cited by 17 · see citing works

Involvement of Alveolar Macrophages and Neutrophils in Acute Lung Injury After Scorpion Envenomation: New Pharmacological Targets

Saidi, H., Bérubé, J., Laraba‐Djebari, F., & Hammoudi-Triki, D. (2018) · Inflammation · doi:10.1007/s10753-018-0731-9 · Cited by 16 · see citing works

The vaccine adjuvant MPLA activates glycolytic metabolism in mouse mDC by a JNK-dependent activation of mTOR-signaling

Blanco‐Pérez, F., Goretzki, A., Wolfheimer, S., & Schülke, S. (2019) · Molecular Immunology · doi:10.1016/j.molimm.2018.12.029 · Cited by 16 · see citing works

TLR2 axis on peripheral blood mononuclear cells regulates inflammatory responses to non-infectious immature dengue virus particles

Aguilar-Briseño, J. A., Pereira, L. R., van der Laan, M., Paužuolis, M., ter Ellen, B. M., Upasani, V., Moser, J., Ferreira, L. C. D. S., Smit, J. M., & Rodenhuis‐Zybert, I. A. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010499 · Cited by 15 · see citing works

Oxytocin Signaling as a Target to Block Social Defeat-Induced Increases in Drug Abuse Reward

Perez, C. F., Reguilón, M. D., Miñarro, J., & Rodríguez‐Arias, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22052372 · Cited by 14 · see citing works

Activation of TGF-β activated kinase 1 promotes colon mucosal pathogenesis in inflammatory bowel disease

Liu, Z., Kong, F., Vallance, J. E., Harmel-Laws, E., Amarachintha, S. P., Steinbrecher, K. A., Rosen, M. J., & Bhattacharyya, S. (2017) · Physiological Reports · doi:10.14814/phy2.13181 · Cited by 13 · see citing works

Long noncoding RNA TARL promotes antibacterial activity and prevents bacterial escape in Miichthys miiuy through suppression of TAK1 downregulation

Zheng, W., Lv, X., Xin, S., Sun, Y., & Xu, T. (2023) · Science China Life Sciences · doi:10.1007/s11427-022-2254-6 · Cited by 13 · see citing works

Glucocorticoids differentially regulate the innate immune responses of TLR4 and the cytosolic DNA sensing pathway

Wang, J., Wang, R., Yang, J., Yang, X., Hu, S., Wang, H., Zhou, C., Xiong, W., Wen, Q., & Ma, L. (2017) · International Immunopharmacology · doi:10.1016/j.intimp.2017.03.022 · Cited by 10 · see citing works

Glucocorticoid receptor in ayu (Plecoglossus altivelis): Genomic and non-genomic effects on monocytes/macrophages function

Ning, Y.-J., Chen, S., Lu, X., Lu, J., & Chen, J. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.12.065 · Cited by 10 · see citing works

Transforming growth factor‐β‐activated kinase 1 resistance limits glucocorticoid responsiveness to Toll‐like receptor 4‐mediated inflammation

Kong, F., Laryea, G. N., Liu, Z., & Bhattacharyya, S. (2014) · Immunology · doi:10.1111/imm.12434 · Cited by 8 · see citing works

NOD1/2 and the C-Type Lectin Receptors Dectin-1 and Mincle Synergistically Enhance Proinflammatory Reactions Both In Vitro and In Vivo

Ильдарович, Т. А., Dzharullaeva, A. S., Erokhova, A. S., Scheblyakov, D. V., Naroditsky, B. S., Al, G., & Logunov, D. Y. (2020) · Journal of Inflammation Research · doi:10.2147/jir.s245638 · Cited by 8 · see citing works

The macrophage infectivity potentiator of Trypanosoma cruzi induces innate IFN-γ and TNF-α production by human neonatal and adult blood cells through TLR2/1 and TLR4

Djebbara, S. A., Mcheik, S., Percier, P., Segueni, N., Poncelet, A., & Truyens, C. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1180900 · Cited by 8 · see citing works

Immune-modulation effect of Halocynthia aurantium tunic lipid on RAW264.7 cells

Jang, A.-Y., Monmai, C., Rod–in, W., Kim, J.-E., You, S., Lee, T., & Park, W. J. (2021) · Food Science and Biotechnology · doi:10.1007/s10068-021-01017-4 · Cited by 7 · see citing works

Anti-inflammatory effect potentials of ethanol extracts from fermentatedCaryopteris incanabyLactobacillus plantarumon induced to LPS with Raw 264.7 cell

Park, M.-J., Park, H., Lee, E., Jung, H., & Cho, Y. (2018) · Journal of Applied Biological Chemistry · doi:10.3839/jabc.2018.021 · Cited by 6 · see citing works

Synthetic stigmastanes with dual antiherpetic and immunomodulating activities inhibit ERK and Akt signaling pathways without binding to glucocorticoid receptors

Michelini, F. M., Bueno, C. A., Molinari, A. M., Galigniana, M. D., Galagovsky, L. R., Alché, L. E., & Ramirez, J. A. (2015) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2015.10.024 · Cited by 5 · see citing works

LncRNA MIR144HG-derived miR-144 suppresses antibacterial signaling and facilitates bacteria escape in fish

Zheng, W., Cui, J., Lv, X., Xin, S., & Xu, T. (2022) · Water Biology and Security · doi:10.1016/j.watbs.2022.100093 · Cited by 5 · see citing works

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Wang, L., Li, Z., Hu, T., Li, Q., Zhang, L., Mei, X., Xiao, Q., Liu, S., Kong, W., Luo, J., et al. (2025) · Advanced Science · doi:10.1002/advs.202509807 · Cited by 4 · see citing works

Housing conditions affect enterocyte death mode and turnover rate in mouse small intestine

Matsuoka, Y., & Tsujimoto, Y. (2023) · Scientific Reports · doi:10.1038/s41598-023-47660-1 · Cited by 1 · see citing works

Alternatively Spliced Forms of Tollip Regulate Inflammatory Signalling in Macrophages

Lo, Y.-L.-S. (2012) · Griffith Research Online · doi:10.25904/1912/891

Chemoresistance of PRAME-expressing melanoma cell can be resolved with help of bortezomib

Misyurin, V. A., Kalenichenko, D., Rudakova, A. A., Finashutina, Y. P., Lyzhko, N. A., Тихонова, В. В., Кесаева, Л. А., Солопова, О. Н., Misyurina, A., Velikanov, A. N., et al. (2019) · Advances in molecular oncology · doi:10.17650/2313-805x-2018-5-4-131-134

Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice

Setia, Y. D., Tanaka, M., Tanaka, R., Yoshida, A., Nagayasu, E., AHMADI, P., Yoshida, A., & Maruyama, H. (2025) · Frontiers in Parasitology · doi:10.3389/fpara.2025.1621486

Screening and characterization of a novel cupin-like polypeptide from Oyster (Ostrea gigas) and its anti-inflammatory effect via TAK1 mediated NF-κB pathway

Li, C., Xiang, Y., Jiang, T., Zhang, J., Xia, X., & Liu, A. (2026) · Food Chemistry X · doi:10.1016/j.fochx.2026.103884

Transforming Growth Factor-β–Activated Kinase 1 Impedes Peripheral Nerve Regeneration after Injury by Evoking Sustained Inflammation

Liu, X., Zhang, S., Wu, Z., Zhang, M., Ju, Q., Tang, X., Chen, Y., & Sun, C. (2026) · American Journal Of Pathology · doi:10.1016/j.ajpath.2026.09.001

Regulation of Toll Like Receptor-3 mediated inflammatory responses by glucocorticoid receptors: Role of MAP Kinases (B66)

Bhattacharyya, S., & Muglia, L. J. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.supp.b66

Transforming growth factor‐β‐activated kinase 1 resistance limits glucocorticoid responsiveness to Toll‐like receptor 4‐mediated inflammation

Kong, F., Laryea, G. N., Liu, Z., & Bhattacharyya, S. (2014) · Immunology · doi:10.1111/imm.12434 · Cited by 8 · see citing works

Glucocorticoids Differentially Target SOCS1 and Type 1 Interferons to Regulate TLR-Induced STAT-1 Activation.

Bhattacharyya, S., & Muglia, L. J. (2009) · Blood · doi:10.1182/blood.v114.22.239.239 · Cited by 2 · see citing works

Inhibition of IRAK1 Ubiquitination Determines Glucocorticoid Sensitivity for TLR9-Induced Inflammation in Macrophages

Kong, F., Liu, Z., Jain, V. G., Shima, K., Suzuki, T., Muglia, L. J., Starczynowski, D. T., Pasare, C., & Bhattacharyya, S. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700443 · Cited by 25 · see citing works

407 Glucocorticoids suppress TLR2/1-induced inflammation while maintaining host defense responses in human macrophages

Kroell, P., Steiger, J., & Fabri, M. (2017) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2017.07.603