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Cited by 1,045

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Systemic effects of chronic obstructive pulmonary disease

Open access
Agustí, A.G.N., Noguera, A., Sauleda, J., Sala, E., Pons, J., Busquets, X.·2003·European Respiratory Journal

Abstract

Chronic obstructive pulmonary disease (COPD) is characterised by an inappropriate/excessive inflammatory response of the lungs to respiratory pollutants, mainly tobacco smoking. Recently, besides the typical pulmonary pathology of COPD (i.e.chronic bronchitis and emphysema), several effects occurring outside the lungs have been described, the so-called systemic effects of COPD. These effects are clinically relevant because they modify and can help in the classification and management of the disease. The present review discusses the following systemic effects of chronic obstructive pulmonary disease: 1) systemic inflammation; 2) nutritional abnormalities and weight loss; 3) skeletal muscle dysfunction; and 4) other potential systemic effects. For each of these, the potential mechanisms and clinical implications are discussed and areas requiring further research are highlighted.

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Registry

Crossref · 10.1183/09031936.03.00405703

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Metadata

Authors
Agustí, A. G. N., Noguera, A., Sauleda, J., Sala, E., Pons, J., & Busquets, X.
Venue
European Respiratory Journal
Published
2003-02
Volume
21
Issue
2
Pages
347-360
ISSN
  • 0903-1936 (ISSN-L)
  • 1399-3003
OpenAlex
W2110378267
Cited by
1,045
References
15
FWCI
32.87
Type
journal article
Language
en
Open access
bronze

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.