Cited by 952Chronic Obstructive Pulmonary Disease (COPD) ResearchMedical Practices and RehabilitationCystic Fibrosis Research Advances

Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial

Griffiths, TL, Burr, ML, Campbell, IA, Lewis-Jenkins, V, Mullins, J, Shiels, K, Turner-Lawlor, PJ, Payne, N +4 more·2000·The Lancet

Abstract

Background Pulmonary rehabilitation seems to be an effective intervention in patients with chronic obstructive pulmonary disease. We undertook a randomised controlled trial to assess the effect of outpatient pulmonary rehabilitation on use of health care and patients' wellbeing over 1 year.Methods 200 patients with disabling chronic lung disease (the majority with chronic obstructive pulmonary disease) were randomly assigned a 6-week multidisciplinary rehabilitation programme (18 visits) or standard medical management. Use of health services was assessed from hospital and general-practice records. Analysis was by intention to treat.Findings There was no difference between the rehabilitation (n=99) and control (n=101) groups in the number of patients admitted to hospital (40 vs 41) but the number of days these patients spent in hospital differed significantly (mean 10.4 [SD 9.7] vs 21.0 [20.7], p=0.022). The rehabilitation group had more primary-care consultations at the general-practitioner's premises than did the control group (8.6 [6.8] vs 7.3 [8.3], p=0.033) but fewer primary-care home visits (1.5 [2.8] vs 2.8 [4.6], p=0.037). Compared with control, the rehabilitation group also showed greater improvements in walking ability and in general and disease-specific health status.Interpretation For patients chronically disabled by obstructive pulmonary disease, an intensive, multidisciplinary, outpatient programme of rehabilitation is an effective intervention, in the short term and the long term, that decreases use of health services.

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Crossref · 10.1016/s0140-6736(99)07042-7

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  • Participation in supervised whole-body exercise training has been shown in several randomized controlled trials to improve symptoms of anxiety and depression as a consequence of training-related gains in functional capacity.

    “Subsequent participation in supervised whole-body exercise training has been shown in several randomized controlled trials95–98 to improve symptoms of anxiety and depression as a consequence of training-related gains in functional capacity.”

    From Anxiety and Depression in COPD (2008) · cites this paper as [97]

  • Griffiths and colleagues reported reduced symptoms of anxiety and depression following a 6-week PR program, with symptoms of depression remaining significantly reduced at 12-month follow-up.

    “Griffiths and colleagues97 reported reduced symptoms of anxiety and depression following a 6-week PR program, with symptoms of depression remaining significantly reduced at 12-month follow-up.”

    From Anxiety and Depression in COPD (2008) · cites this paper as [97]

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Authors
Griffiths, T., Burr, M., Campbell, I., Lewis-Jenkins, V, Mullins, J., Shiels, K., Turner-Lawlor, P., Payne, N., Newcombe, R., Lonescu, A., Thomas, J., & Tunbridge, J.
Venue
The Lancet
Publisher
Elsevier BV
Published
2000-01
Volume
355
Issue
9201
Pages
362-368
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
OpenAlex
W2170075933
Cited by
952
References
33
Citations by year
2026: 9 · 2025: 13 · 2024: 19 · 2023: 21 · 2022: 21 · 2021: 21 · 2020: 23 · 2019: 32 · 2018: 32 · 2017: 36 · 2016: 35 · 2015: 44 · 2014: 50 · 2013: 40 · 2012: 38
FWCI
33.11
Type
journal article
Language
en
Open access
closed
Locations
  • The Lancet (publishedVersion)
  • PubMed (publishedVersion)
  • ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
Funders
Office of Research and Development
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Medical Practices and Rehabilitation
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
Keywords
pulmonary rehabilitation, chronic obstructive pulmonary disease, outpatient rehabilitation, multidisciplinary rehabilitation, health care utilization, hospitalization, primary care visits, walking ability, health status, long-term outcomes
MeSH terms
Aged, Ambulatory Care, Dietary Services, Exercise Therapy, Female, Health Services, Humans, Lung Diseases, Obstructive, Male, Occupational Therapy, Patient Education as Topic, Quality of Life, Respiratory Mechanics, Physical Therapy Modalities

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