Risk factors for rehospitalisation in COPD: role of health status, anxiety and depression
Open accessAbstract
The aim of the present study was to analyse the risk of rehospitalisation in patients with chronic obstructive pulmonary disease and associated risk factors. This prospective study included 416 patients from a university hospital in each of the five Nordic countries. Data included demographic information, spirometry, comorbidity and 12 month follow-up for 406 patients. The hospital anxiety and depression scale and St. George's Respiratory Questionnaire (SGRQ) were applied to all patients. The number of patients that had a re-admission within 12 months was 246 (60.6%). Patients that had a re-admission had lower lung function and health status. A low forced expiratory volume in one second (FEV 1) and health status were independent predictors for re-admission. Hazard ratio (HR; 95% CI) was 0.82 (0.74–0.90) per 10% increase of the predicted FEV 1 and 1.06 (1.02–1.10) per 4 units increase in total SGRQ score. The risk of rehospitalisation was also increased in subjects with anxiety (HR 1.76 (1.16–2.68)) and in subjects with low health status (total SGRQ score >60 units). When comparing the different subscales in the SGRQ, the closest relation between the risk of rehospitalisation was seen with the activity scale (HR 1.07 (1.03–1.11) per 4 unit increase). In patients with low health status, anxiety is an important risk factor for rehospitalisation. This may be important for patient treatment and warrants further studies.
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By compromising health status, mood disorders lead to increased risk of hospitalisation and re-hospitalisation and hence also increase direct and indirect costs to the health system.
“By compromising health status, mood disorders lead to increased risk of hospitalisation and re-hospitalisation (Gudmundsson 2005) and hence also increase direct and indirect costs to the health system.”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Gudmundsson 2005
The Abstract and Discussion report an increased risk of rehospitalisation among COPD patients with anxiety and low health status. They do not establish that mood disorders cause poor health status or increased hospitalisation generally; the Discussion explicitly reports no association between depression and readmission. The cost statement follows the citation as the citing authors’ inference, rather than a finding attributed to this source. (LLM, conf=0.89)
Experimental — accuracy not yet measuredMood disorders may lead to increased risk of hospitalization and rehospitalization by compromising health status.
“By compromising health status, mood disorders may lead to increased risk of hospitalization59 and rehospitalization.60”
From Anxiety and Depression in COPD (2008) · cites this paper as [60]
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- Authors
- Gudmundsson, G., Gislason, T., Janson, C., Lindberg, E., Hallin, R., Ulrik, C. S., Brøndum, E., Nieminen, M. M., Aine, T., & Bakke, P.
- Affiliations
- National University Hospital of Iceland (IS)
- Uppsala University (SE)
- Amager Hospital (DK)
- University of Copenhagen (DK)
- Tampere University Hospital (FI)
- Haukeland University Hospital (NO)
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2005-09
- Volume
- 26
- Issue
- 3
- Pages
- 414-419
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2123606343
- Cited by
- 366
- References
- 29
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 15 · 2023: 17 · 2022: 15 · 2021: 7 · 2020: 13 · 2019: 12 · 2018: 16 · 2017: 24 · 2016: 18 · 2015: 27 · 2014: 22 · 2013: 23 · 2012: 19
- FWCI
- 14.70
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Respiratory Journal (publishedVersion)
- PubMed (publishedVersion)
- Hirsla (Landspítali University Hospital) (submittedVersion)
- Funders
- Riksförbundet HjärtLung
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Keywords
- chronic obstructive pulmonary disease, hospital readmission, risk factors, anxiety, depression, health status, St George's Respiratory Questionnaire, lung function, FEV1, comorbidities, activity limitation
- MeSH terms
- Aged, Aged, 80 and over, Anxiety, Depression, Female, Follow-Up Studies, Health Status, Health Surveys, Humans, Male, Middle Aged, Patient Readmission, Prospective Studies, Risk Factors, Pulmonary Disease, Chronic Obstructive
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