Abnormal pulmonary function in COVID-19 patients at time of hospital discharge
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In discharged survivors with COVID-19, impairment of diffusion capacity is the most common abnormality of lung function, followed by restrictive ventilatory defects, which are both associated with the severity of the diseasehttps://bit.ly/2yUaBaT
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Patients with severe COVID-19 were found to have a high rate of fibrotic lung function abnormalities at hospital release.
“Furthermore, patients with severe COVID-19 were found to have a high rate of fibrotic lung function abnormalities at hospital release, highlighting important implications for long-term health complications (54).”
From Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19 (2021) · cites this paper as [54]
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Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy
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- Authors
- Mo, X., Jian, W., Su, Z., Chen, M., Peng, H., Peng, P., Lei, C., Chen, R., Zhong, N., & Li, S.
- Affiliations
- Guangzhou Eighth People's Hospital (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Corresponding author
- Li, Shiyue
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2020-05-07
- Volume
- 55
- Issue
- 6
- Pages
- 2001217
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- PMC
- PMC7236826
- OpenAlex
- W3020946865
- Cited by
- 810
- References
- 10
- Citations by year
- 2026: 17 · 2025: 38 · 2024: 74 · 2023: 112 · 2022: 186 · 2021: 292 · 2020: 91
- FWCI
- 22.34
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- European Respiratory Journal (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- Guangzhou Medical University
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- COVID-19 pandemic, lung function, lung function impairment, diffusion capacity, restrictive ventilatory defect, hospital discharge, disease severity, post-COVID-19 lung function
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Adult, Aged, China, Diabetes Mellitus, Female, Forced Expiratory Volume, Humans, Hypertension, Lung, Male, Maximal Midexpiratory Flow Rate, Middle Aged, Oxygen, Patient Discharge, Pneumonia, Viral, Pulmonary Diffusing Capacity, Severity of Illness Index, Smoking, Spirometry, Tomography, X-Ray Computed, Vital Capacity, Comorbidity, Survivors, Coronavirus Infections, Lung Injury, Pandemics
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