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pain DETECT : a new screening questionnaire to identify neuropathic components in patients with back pain
Open accessAbstract
OBJECTIVE: Nociceptive and neuropathic components both contribute to pain. Since these components require different pain management strategies, correct pain diagnosis before and during treatment is highly desirable. As low back pain (LBP) patients constitute an important subgroup of chronic pain patients, we addressed the following issues: (i) to establish a simple, validated screening tool to detect neuropathic pain (NeP) components in chronic LBP patients, (ii) to determine the prevalence of neuropathic pain components in LBP in a large-scale survey, and (iii) to determine whether LBP patients with an NeP component suffer from worse, or different, co-morbidities. METHODS: In co-operation with the German Research Network on Neuropathic Pain we developed and validated the painDETECT questionnaire (PD-Q) in a prospective, multicentre study and subsequently applied it to approximately 8000 LBP patients. RESULTS: The PD-Q is a reliable screening tool with high sensitivity, specificity and positive predictive accuracy; these were 84% in a palm-top computerised version and 85%, 80% and 83%, respectively, in a corresponding pencil-and-paper questionnaire. In an unselected cohort of chronic LBP patients, 37% were found to have predominantly neuropathic pain. Patients with NeP showed higher ratings of pain intensity, with more (and more severe) co-morbidities such as depression, panic/anxiety and sleep disorders. This also affected functionality and use of health-care resources. On the basis of given prevalence of LBP in the general population, we calculated that 14.5% of all female and 11.4% of all male Germans suffer from LBP with a predominant neuropathic pain component. CONCLUSION: Simple, patient-based, easy-to-use screening questionnaires can determine the prevalence of neuropathic pain components both in individual LBP patients and in heterogeneous cohorts of such patients. Since NeP correlates with more intense pain, more severe co-morbidity and poorer quality of life, accurate diagnosis is a milestone in choosing appropriate therapy.
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“Participants will be randomized to stratified blocks based on sex/gender and pain type (neuropathic, non-neuropathic, mixed or undetermined), assessed via the Pain DETECT[50] measure and the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS)[51] to ensure uniform distribution of these factors across the three conditions.”
From The chronic pain skills study: Protocol for a randomized controlled trial comparing hypnosis, mindfulness meditation and pain education in Veterans (2020) · cites this paper as [51]
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“This is a popular well-validated measure of pain severity used in research and clinical settings.”
From Risk Factors for Self-Harm Ideation among Persons Treated with Opioids for Chronic Low Back Pain (2023) · cites this paper as [33]
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InfluentialBrunelli, C., Bennett, M., Kaasa, S., Fainsinger, R. L., Sjøgren, P., Mercadante, S., Lhre, E. T., & Caraceni, A. T. (2014) · Pain · doi:10.1016/j.pain.2014.09.038 · Cited by 36
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MethodEvaluation of Symptom Heterogeneity in Neuropathic Pain Using Assessments of Sensory Functions
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Self-citationChronic pain patients’ treatment preferences: a discrete-choice experiment
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“Patients with neuropathic pain showed higher ratings of pain intensity, with more co-morbidities such as depression, panic/anxiety, and sleep disorders [2].”
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“After the replication phase of the study, clinical data from the 360 patients were analyzed together in a common final analysis, and at this stage, the following neuropathic pain questionnaires were included: the Douleur Neuropathique en 4 Questions (DN4), 9 PainDETECT, 27 and the Neuropathic Pain Symptom Inventory (N…”
Moisset, X., Cornut-Chauvinc, C., Clavelou, P., Pereira, B., Dallel, R., & Guy, N. (2015) · Palliative Medicine · doi:10.1177/0269216315600332 · Cited by 35
Clinical characteristics of pain in patients with pituitary adenomas.
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Self-citationAn Analysis of the Neuropathic Pain Components in Rheumatoid Arthritis Patients
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“During our study, two papers were published on NeP in RA patients (3, 5).”
BackgroundMethodInfluentialDiagnostic work‐up of neuropathic pain: Computing, using questionnaires or examining the patient?
Hansson, P. T., & Haanpää, M. L. (2007) · European Journal of Pain · doi:10.1016/j.ejpain.2006.12.005 · Cited by 35
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“The painDETECT questionnaire which is validated for the use in back pain patients captures the characteristic neuropathic symptoms and can estimate the intensity of each symptom quantitatively (Freynhagen et al., 2006).”
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Effect of Postoperative Administration of Pregabalin for Post-thoracotomy Pain: A Randomized Study
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“There are many screening tools to identify neuropathic pain, including the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS), DN4, NPQ, painDETECT, ID-pain, and StEP questionnaire [20-24].”
BackgroundMarkman, J. D., Kress, B. T., Frazer, M. E., Hanson, R., Kogan, V., & Huang, J. H. (2014) · Pain Medicine · doi:10.1111/pme.12612 · Cited by 34
Smart, K. M., Curley, A., Blake, C. M., Staines, A. S., & Doody, C. (2010) · Journal of Manual & Manipulative Therapy · doi:10.1179/106698110x12640740712897 · Cited by 33
Vollert, J., Kramer, M., Barroso, A., Freynhagen, R., Haanpää, M. L., Hansson, P. T., Jensen, T. S., Kuehler, B. M., Maier, C., Mainka, T., et al. (2016) · Pain · doi:10.1097/j.pain.0000000000000588 · Cited by 33
“The PDQ is a validated screening tool developed to aid in identifying NP and NP components.(12,6) It comprises 9 items regarding the severity, course, quality, and nature of the patient’s pain.”
MethodInfluentialSelf-citationPrevalence of Persistent Pain after Total Knee Arthroplasty and the Impact of Neuropathic Pain
Hasegawa, M., Tone, S., Naito, Y., Wakabayashi, H., & Sudo, A. (2018) · The Journal of Knee Surgery · doi:10.1055/s-0038-1675415 · Cited by 33
Vining, R. D., Shannon, Z. K., Minkalis, A. L., & Twist, E. J. (2019) · Journal of Manipulative and Physiological Therapeutics · doi:10.1016/j.jmpt.2019.08.002 · Cited by 37
Kimura, Y., Yamaguchi, S., Suzuki, T., Kato, J., Chiba, S., Hirakawa, N., Yamaguchi, K., Tanabe, Y., Takatsuna, H., Kenyoshi, Y., et al. (2021) · Pain and Therapy · doi:10.1007/s40122-021-00255-y · Cited by 33
“disorder, and sleep disorders than those with nociceptive pain, which can negatively impact their quality of life [5].”
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“Low back pain is a heterogeneous condition, involving lesions of specific structures of the spine [9], subclinical neuropathic components [14] and, probably, variable degrees of central plastic changes.”
BackgroundExercise-Induced Modulation of Pain in Adults With and Without Painful Diabetic Neuropathy
Knauf, M. T., & Koltyn, K. F. (2014) · Journal of Pain · doi:10.1016/j.jpain.2014.02.008 · Cited by 33
Visser, E., Ramachenderan, J., Davies, S., & Parsons, R. W. (2014) · Pain Practice · doi:10.1111/papr.12263 · Cited by 33
“A PD-Q score of ≥ 19 was chosen as an indicator of pain sensitization or neuropathic pain based on the studies of Freynhagen et al.20 and Amris et al.6 AWPI score of ≥ 7 was chosen as a comparative indicator of CWP based on the paper byWoolfe et al.,22 which reported that 87.9% of patients with American College of Rhe…”
MethodInfluentialNeuropathic Pain Component in Axial Spondyloarthritis and the Influence on Disease Burden
Gök, K., Cengiz, G., Erol, K., & Özgöçmen, S. (2018) · JCR Journal of Clinical Rheumatology · doi:10.1097/rhu.0000000000000711 · Cited by 33
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“The authors of Pain DETECT reported that radiculopathies, considered mixed pain syndromes (inflammatory and neuropathic components), have clinical characteristics similar to definite neuropathic pain.(11) Perez et al(19) came to similar conclusions using the DN4 where a score of 4 or more indicates neuropathic pain.”
Morsø, L., Kent, P. M., & Albert, H. (2011) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e318208c941 · Cited by 32
“2) (14-85) Missing (n) 2 n (%) Sex Men 56 (38.”
Longitudinal Assessment of Pain Outcomes in the Clinical Setting
Hassett, A. L., Wasserman, R. A., Goesling, J., Rakovitis, K., Shi, B., & Brummett, C. M. (2012) · Regional Anesthesia & Pain Medicine · doi:10.1097/aap.0b013e3182524672 · Cited by 32
The characterisation of unexplained pain after knee replacement
Phillips, J., Hopwood, B., Stroud, R., Dieppe, P. A., & Toms, A. D. (2017) · British Journal of Pain · doi:10.1177/2049463717719774 · Cited by 33
Are Opioids Effective in Relieving Neuropathic Pain?
Schembri, E. (2018) · SN Comprehensive Clinical Medicine · doi:10.1007/s42399-018-0009-4 · Cited by 37
Alkhatatbeh, M. J., & Abdul‐Razzak, K. K. (2019) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2019-000690 · Cited by 32
“For example, the neuropathy status was not determined clinically but was determined by self-reporting using the PainDETECT questionnaire.(28) As well, we only used one assessment tool for neuropathy and we did not compare the validity of this tool compared with other questionnaires that were used previously to assess…”
BackgroundMethodHasani, F., Haines, T. P., Munteanu, S. E., Schoch, P., Vicenzino, B., & Malliaras, P. (2021) · BMC Sports Science Medicine and Rehabilitation · doi:10.1186/s13102-021-00279-z · Cited by 37
“5D 5 L index value and overall health state [VAS]); (vi) Physical activity using 7-day Recall Physical Activity Questionnaire [32]; (vii) Fear of movement or re-injury: Kinesiophobia was measured with the Tampa Scale for Kinesiophobia (TSK) [33]; (viii) Pain catastrophising was measured using the Pain Catastrophising…”
MethodCoxon, L., Wiech, K., & Vincent, K. (2021) · Frontiers in Pain Research · doi:10.3389/fpain.2021.743812 · Cited by 35
“PainDETECT standard cut-off scores were used to group participants into those with nociceptive (≤12), mixed (13-18) and neuropathic-like (≥19) pain17.”
MethodOrita, S., Yamashita, M., Eguchi, Y., Suzuki, M., Inoue, G., Miyagi, M., Watanabe, T., Ozawa, T., Kamoda, H., Ishikawa, T., et al. (2016) · Pain Research and Management · doi:10.1155/2016/5079675 · Cited by 32
“PGB-naı̈ve LSS patients with low back and leg pain aged 20–90 years who were diagnosed with chronic NeP using the Pain DETECT questionnaire (PD-Q), which is a patientoriented and validated screening tool, were included in this study [9] (Table 1).”
MethodWright, A., Benson, H. A., Will, R., & Moss, P. (2016) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000458 · Cited by 32
Schäfer, A. G. M., Joos, L., Roggemann, K., Waldvogel-Röcker, K., Pfingsten, M., & Petzke, F. W. (2017) · PLoS ONE · doi:10.1371/journal.pone.0182207 · Cited by 32
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Pramhas, S., Thalhammer, T., Terner, S., Pickelsberger, D., Gleiß, A., Sator, S., & Kress, H. G. (2023) · The Lancet Regional Health - Europe · doi:10.1016/j.lanepe.2023.100777 · Cited by 37
Harrison-Felix, C., Sevigny, M., Beaulieu, C. L., Callender, L., Dams-O’Connor, K., Hammond, F. M., Hanks, R. A., Ketchum, J. M., Martin, A. M., Marwitz, J. H., et al. (2024) · Journal of Head Trauma Rehabilitation · doi:10.1097/htr.0000000000000910 · Cited by 31
“Neuropathic pain type was measured using the 9-item PainDETECT Questionnaire 30 and classified as clinically significant positive, clinically significant negative, or unclear.”
MethodElias, L. A. M. S., Yilmaz, Z., Smith, J. G., Bouchiba, M., van der Valk, R. A., Page, L., Barker, S., & Renton, T. F. (2013) · International Journal of Oral and Maxillofacial Surgery · doi:10.1016/j.ijom.2013.07.004 · Cited by 31
“It was originally developed and validated in German, in a multicentre study of chronic low back pain patients, and appears to be a reliable screening tool in this diagnostic group: it has a sensitivity of 85%, specificity of 80%, and positive predictive value of 83%.(9) The PD-Q has subsequently been translated into 2…”
BackgroundMethodResultInfluentialMorville, A.-L., Amris, K., Eklund, M., Danneskiold‐Samsøe, B., & Erlandsson, L. (2014) · Journal of Immigrant and Minority Health · doi:10.1007/s10903-014-0004-0 · Cited by 31
“In order to predict the likelihood of neuropathic pain the Pain Detect Questionnaire (PDQ) was used [18].”
InfluentialHopkins, K. G., Hoffman, L. A., Dabbs, A. D. V., Ferson, P. F., Linda King, M., Dudjak, L. A., Zullo, T. G., & Rosenzweig, M. Q. (2015) · Journal of the Advanced Practitioner in Oncology · doi:10.6004/jadpro.2015.6.2.4 · Cited by 31
“A targeted physical assessment (Hopkins & Rosenzweig, 2012) and/or brief questionnaires can guide evaluation of response to therapy (Bennett et al., 2007; Bousassira & Attal, 2011; Freynhagen et al., 2006; McGill, 2009).”
Garoushi, S., Johnson, M. I., & Tashani, O. A. (2019) · BMC Public Health · doi:10.1186/s12889-018-6374-9 · Cited by 32
Rovati, L. C., Brambilla, N., Blicharski, T., Connell, J., Vitalini, C., Bonazzi, A., Giacovelli, G., Girolami, F., & D’Amato, M. (2019) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2019.09.002 · Cited by 31
Kim, J.-K., Park, H. S., Bae, J. S., Jeong, Y. S., Jung, K. J., & Lim, J. Y. (2020) · Neurorehabilitation · doi:10.3233/nre-192958 · Cited by 31
“…(DN4), ID pain, painDETECT, and the standardized evaluation of pain (StEP) (M. Bennett, 2001; M. I. Bennett, Smith, Torrance & Potter, 2005; Bouhassira et al., 2005; Cruccu et al., 2009; Freynhagen, Baron, Gockel & Tolle, 2006; Krause & Backonja, 2003; Portenoy, 2006; Scholz et al., 2009).”
Cross-cultural adaptation and validation of the German Central Sensitization Inventory (CSI-GE)
Klute, M., Laekeman, M., Kuss, K., Petzke, F. W., Dieterich, A. V., Leha, A., Neblett, R., Ehrhardt, S., Ulma, J., & Schäfer, A. G. M. (2021) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-021-04481-5 · Cited by 31
Skin biopsy reveals generalized small fibre neuropathy in hypermobile Ehlers–Danlos syndromes
Igharo, D., Thiel, J. C., Rolke, R., Akkaya, M., Weis, J., Katona, I., Schulz, J. B., & Maier, A. (2022) · European Journal of Neurology · doi:10.1111/ene.15649 · Cited by 32
“71) [22], the Small Fibre Neuropathy Screening List (SFNSL; Cronbach's alpha = 0.”
BackgroundVægter, H. B., Andersen, P. G., Madsen, M. F., Handberg, G., & Enggaard, T. P. (2013) · Pain Medicine · doi:10.1111/pme.12273 · Cited by 31
Zajonz, D., Franke, A.-C., von der Höh, N., Voelker, A., Moche, M., Gulow, J., & Heyde, C. (2014) · Patient Safety in Surgery · doi:10.1186/preaccept-4877663801356666 · Cited by 31
Prevalence and Location of Neuropathic Pain in Lumbar Spinal Disorders
Orita, S., Yamashita, T., Ohtori, S., Yonenobu, K., Kawakami, M., Taguchi, T., Kikuchi, S.-I., Ushida, T., Konno, S.-I., Nakamura, M., et al. (2016) · Spine · doi:10.1097/brs.0000000000001553 · Cited by 32
Gløersen, M., Mulrooney, E., Mathiessen, A., Hammer, H. B., Slatkowsky-Christensen, B., Faraj, K., Isaksen, T., Neogi, T., Kvien, T. K., Magnusson, K., et al. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-016938 · Cited by 31
“Questionnaires like PainDETECT have been developed to identify neuropathic pain, originally in patients with low back pain.(37) In this study, we use a modified version of the PainDETECT questionnaire to assess possible neuropathic-like pain in the hands, like has been done in previous studies of knee OA.”
Neural Tissue Evaluation and Treatment
Elvey, R. L., & Hall, T. M. (2004) · Elsevier eBooks · doi:10.1016/b978-044306614-6.50008-9 · Cited by 31
Hamdan, A., Gálvez, R., & Katati, M. J. (2024) · SAGE Open Medicine · doi:10.1177/20503121231218985 · Cited by 34
“8,96 Different questionnaires have been developed for the identification of NP (e.g., LANSS, 77 the NPQ, 79 the DN4, 78 and painDETECT 80 ), but they have been examined in only a few studies in central pain, and in general, such questionnaires cannot be used as the sole diagnostic tool for an…”
BackgroundLópez‐de‐Uralde‐Villanueva, I., Beltrán-Alacreu, H., Fernández‐Carnero, J., Gil‐Martínez, A., & Touche, R. L. (2015) · Pain Medicine · doi:10.1111/pme.12856 · Cited by 30
Brunelli, C., Kaasa, S., Knudsen, A. K., Hjermstad, M. J., Pigni, A., & Caraceni, A. T. (2013) · Journal of Pain · doi:10.1016/j.jpain.2013.09.011 · Cited by 30
Kahraman, T., Özdoğar, A. T., Yiğit, P., Hosgel, I., Mehdiyev, Z., Ertekin, Ö., & Özakbaş, S. (2017) · EXPLORE · doi:10.1016/j.explore.2017.07.006 · Cited by 30
“The PainDETECT Questionnaire was designed to assess the pain and distinguish between nociceptive and neuropathic pain.(21) It includes questions about the most severe and average pain intensity over the last 4 weeks and the duration and characteristics of the pain, and the painful areas are marked on a body diagram.”
MethodNikaido, T., Sumitani, M., Sekiguchi, M., & Konno, S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0193987 · Cited by 30
McAlindon, T. E., Schmidt, U., Bugarin, D., Abrams, S., Geib, T., DeGryse, R. E., Kim, K., & Schnitzer, T. J. (2018) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2018.05.001 · Cited by 30
Schilder, A., Magerl, W., Klein, T., & Treede, R. (2018) · PAIN Reports · doi:10.1097/pr9.0000000000000662 · Cited by 30
Özcan, D. S., Tatlı, H. U., Polat, C. S., Öken, Ö., & Köseoğlu, B. F. (2019) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2019.03.002 · Cited by 30
Geritz, J., Mätzold, S., Steffen, M., Pilotto, A., Corrà, M. F., Moscovich, M., Rizzetti, M. C., Borroni, B., Padovani, A., Alpes, A., et al. (2020) · BMC Geriatrics · doi:10.1186/s12877-020-1445-z · Cited by 30
Self-citationMacedo, L. G., Hodges, P. W., Bostick, G. P., Hancock, M. J., Laberge, M., Hanna, S., Spadoni, G., Gross, A., & Schneider, J. A. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-042792 · Cited by 32
Small fiber neuropathy: Swiss cohort characterization
Bitzi, L. M., Lehnick, D., & Wilder-Smith, E. P. (2021) · Muscle & Nerve · doi:10.1002/mus.27340 · Cited by 29
“The painDETECT questionnaire was developed to detect neuropathic pain in patients with chronic low back pain.(13) It consists of questions on pain intensity (at the time of testing, highest pain, and average pain) plus characterization of sensory symptoms.”
Garip, Y., Filiz, E. S. E. R., KILIÇARSLAN, A., & BODUR, H. (2015) · Archives of Rheumatology · doi:10.5606/archrheumatol.2015.5295 · Cited by 30
Epithelial growth factor receptor (EGFR)-inhibition for relief of neuropathic pain–A case series
Kersten, C., Cameron, M. G., & Mjåland, S. (2013) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2012.11.011 · Cited by 30
Failed back surgery syndrome: What's in a name? A proposal to replace “FBSS” by “POPS”…
Rigoard, P., Desai, M. J., & Taylor, R. S. (2015) · Neurochirurgie · doi:10.1016/j.neuchi.2014.12.001 · Cited by 30
Diagnosis and assessment of neuropathic pain
May, S., & Serpell, M. G. (2009) · F1000 Medicine Reports · doi:10.3410/m1-76 · Cited by 30
Finco, G., Locci, E., Mura, P., Massa, R., Noto, A., Musu, M., Landoni, G., d’Aloja, E., De‐Giorgio, F., Scano, P., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0150476 · Cited by 30
“Ambulatory nurse administered the PainDETECT Questionnaire (PDQ) and two experienced pain specialists independently examined all the patients in accordance with the current gold standard [6] to discriminate the pain as predominantly nociceptive or neuropathic.”
MethodSymptom-Based Treatment of Neuropathic Pain in Spinal Cord-Injured Patients
Min, K., Oh, Y., Lee, S., & Ryu, J. S. (2015) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0000000000000382 · Cited by 30
Pain and pain management in hospitalized patients before and after an intervention
Andersson, V., Bergman, S., Henoch, I., Ene, K. W., Otterström-Rydberg, E., Simonsson, H., & Ahlberg, K. (2016) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2016.11.006 · Cited by 30
Javanshir, N., Salehpour, F., Aghazadeh, J., Mirzaei, F., & Alavi, S. A. N. (2017) · European Spine Journal · doi:10.1007/s00586-017-5219-z · Cited by 30
TRPA1 rare variants in chronic neuropathic and nociplastic pain patients
Marchi, M., Salvi, E., Andelic, M., Mehmeti, E., D'Amato, I., Cazzato, D., Chiappori, F., Lombardi, R., Cartelli, D., Devigili, G., et al. (2023) · Pain · doi:10.1097/j.pain.0000000000002905 · Cited by 29
“17 The Douleur Neuropathique 4 questions 8 and the 9-item adjusted PainDetect 28 were used to screen those individuals with higher probability of having neuropathic pain.”
Mohamad, F. A., Rodríguez, V. R., Haibel, H., Protopopov, M., Rademacher, J., Sieper, J., Torğutalp, M., Käding, H., Proft, F. N., & Poddubnyy, D. (2024) · RMD Open · doi:10.1136/rmdopen-2023-004009 · Cited by 30
Stamer, U. M., Lavand'homme, P. M., Hofer, D. M., Barke, A., & Korwisi, B. (2025) · British Journal of Anaesthesia · doi:10.1016/j.bja.2025.02.005 · Cited by 32
Karst, M., Meißner, W., Sator, S., Keßler, J., Schoder, V., & Häuser, W. (2025) · Nature Medicine · doi:10.1038/s41591-025-03977-0 · Cited by 29
Chronic Neuropathic Pain in SCI
Felix, E. R. (2014) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2014.04.007 · Cited by 29
Sanders, D., Krause, K., O’Muircheartaigh, J., Thacker, M. A., Huggins, J. P., Vennart, W., Massat, N. J., Choy, E., Williams, S., & Howard, M. A. (2014) · Arthritis & Rheumatology · doi:10.1002/art.38987 · Cited by 30
Compounded Topical Pain Creams to Treat Localized Chronic Pain
Brutcher, R. E., Kurihara, C., Bicket, M. C., Moussavian-Yousefi, P., Reece, D. E., Solomon, L. M., Griffith, S. R., Jamison, D. E., & Cohen, S. P. (2019) · Annals of Internal Medicine · doi:10.7326/m18-2736 · Cited by 29
Metadata
- Authors
- Freynhagen, R., Baron, R., Gockel, U., & Tölle, T. R.
- Affiliations
- Düsseldorf University Hospital (DE)
- University Hospital Schleswig-Holstein (DE)
- Pfizer (Germany) (DE)
- Technical University of Munich (DE)
- Corresponding author
- Freynhagen, Rainer
- Venue
- Current Medical Research and Opinion
- Publisher
- Informa UK Limited
- Published
- 2006-08-29
- Volume
- 22
- Issue
- 10
- Pages
- 1911-1920
- ISSN
- 0300-7995 (ISSN-L)
- 1473-4877
- OpenAlex
- W2154693681
- Cited by
- 2,280
- References
- 25
- Citations by year
- 2026: 158 · 2025: 182 · 2024: 187 · 2023: 177 · 2022: 172 · 2021: 179 · 2020: 149 · 2019: 121 · 2018: 161 · 2017: 128 · 2016: 130 · 2015: 99 · 2014: 99 · 2013: 102 · 2012: 68
- FWCI
- 12.54
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Current Medical Research and Opinion (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- neuropathic pain, low back pain, chronic pain, painDETECT questionnaire, screening questionnaire, prevalence, comorbidities, depression, anxiety, sleep disorders, pain intensity, quality of life, health care utilization, pain diagnosis
- MeSH terms
- Adult, Aged, Chronic Disease, Female, Humans, Male, Middle Aged, Prospective Studies, Surveys and Questionnaires, Sensitivity and Specificity, Comorbidity, Low Back Pain
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