Accuracy of perception of ovulation day in women trying to conceive
Abstract
BACKGROUND: The likelihood of conception is increased if intercourse is timed to coincide with the fertile period (5 days up to ovulation). However, to be effective, this requires good awareness of the day of ovulation. The aim of this study was to examine the accuracy of women's perceived ovulation day, compared with actual fertile days, in a cohort of women trying to conceive. MAIN OUTCOME MEASURES: Comparison of women's estimated day of ovulation with their actual ovulation day (determined by detecting luteinising hormone). METHODS: This was a sample collection study and volunteer women were recruited via online advertising. At recruitment volunteers reported the cycle day they believed they ovulated. They then used a home urine fertility monitor to test their daily fertility status to time intercourse to try and achieve conception, in addition to collecting early morning urine samples for laboratory analysis. The main outcome measure was a comparison of women's estimated day of ovulation with their actual ovulation day, as determined by urine detection of luteinising hormone. RESULTS: Three hundred and thirty women were recruited onto the study and data was available for 102 volunteers who became pregnant. Thirteen women (12.7%) correctly estimated their ovulation day; median difference +2 days, range -10 to +27 days. The most common days for estimation of ovulation were day 14 (35.5%) and day 15 (15.7%). Only 55% of estimated ovulation days fell within the volunteers' fertile window; only 27% on days of peak fertility. CONCLUSIONS: Women trying to conceive may benefit from using a prospective method to identify their fertile phase, as a significant proportion could be incorrectly estimating their fertile days. These observations were made on women who were actively looking for knowledge on fertility and considered only cycles where conception occurred, inaccuracy could be greater if a broader population is considered.
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Incorrect timing of intercourse appears to be an important reason for couples failing to conceive, due to a combination of lack of fertility knowledge and inaccurate perception of their own menstrual cycles.
“Incorrect timing of intercourse appears to be an important reason for couples failing to conceive, due to a combination of lack of fertility knowledge and inaccurate perception of their own menstrual cycles (Zinaman et al. 2012).”
From Real-life insights on menstrual cycles and ovulation using big data (2020) · cites this paper as Zinaman et al. 2012
Cites
Wilcox, A. J., Weinberg, C. R., & Baird, D. D. (1995) · New England Journal of Medicine · doi:10.1056/nejm199512073332301 · Cited by 1,071 · see citing works
Sex in America: a definitive survey
(1995) · Choice Reviews Online · doi:10.5860/choice.32-4802 · Cited by 481 · see citing works
Gnoth, C. (2003) · Human Reproduction · doi:10.1093/humrep/deg366 · Cited by 457 · see citing works
Behre, H. M., Kuhlage, J., Gaβner, C., Sonntag, B., Schem, C., Schneider, H. P. G., & Nieschlag, E. (2000) · Human Reproduction · doi:10.1093/humrep/15.12.2478 · Cited by 238 · see citing works
How regular is regular? An analysis of menstrual cycle regularity
Creinin, M. D., Keverline, S., & Meyn, L. A. (2004) · Contraception · doi:10.1016/j.contraception.2004.04.012 · Cited by 168 · see citing works
The normal variabilities of the menstrual cycle
Cole, L. A., Ladner, D. G., & Byrn, F. W. (2009) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.11.073 · Cited by 152 · see citing works
Baird, D. D., McConnaughey, D. R., Weinberg, C. R., Musey, P. L., Collins, D. C., Kesner, J. S., Knecht, E. A., & Wilcox, A. J. (1995) · Epidemiology · doi:10.1097/00001648-199509000-00015 · Cited by 142 · see citing works
Efficacy of methods for determining ovulation in a natural family planning program
Guida, M., Tommaselli, G. A., Palomba, S., Pellicano, M., Moccia, G., Carlo, C. D., & Nappi, C. (1999) · Fertility and Sterility · doi:10.1016/s0015-0282(99)00365-9 · Cited by 124 · see citing works
Monitoring techniques to predict and detect ovulation
Vermesh, M., Kletzky, O. A., Davajan, V., & Israel, R. H. (1987) · Fertility and Sterility · doi:10.1016/s0015-0282(16)50002-8 · Cited by 116 · see citing works
Duration Of Human Singleton Pregnancy: A Population‐based Study
Bergsjø, P., Denman, D. W., Hoffman, H. J., & Meirik, O. (1990) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349009028681 · Cited by 109 · see citing works
Vulvar mucus observations and the probability of pregnancy
Stanford, J. B. (2003) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(03)00358-2 · Cited by 91 · see citing works
Temporal relationships between indices of the fertile period
World Health Organization (1983) · Fertility and Sterility · doi:10.1016/s0015-0282(16)47060-3 · Cited by 78 · see citing works
Effects of Sexual Intercourse Patterns in Time to Pregnancy Studies
Stanford, J. B., & Dunson, D. B. (2007) · American Journal of Epidemiology · doi:10.1093/aje/kwk111 · Cited by 76 · see citing works
Tanabe, K. (2001) · Human Reproduction · doi:10.1093/humrep/16.8.1619 · Cited by 67 · see citing works
Johnson, S. R., Miro, F., Barrett, S., & Ellis, J. E. (2009) · Current Medical Research and Opinion · doi:10.1185/03007990902743935 · Cited by 54 · see citing works
At home testing: optimizing management for the infertility physician
Brezina, P. R., Haberl, E. M., & Wallach, E. E. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.01.001 · Cited by 54 · see citing works
Lynch, C. D.-J., Jackson, L. W., & Louis, G. M. B. (2006) · Paediatric and Perinatal Epidemiology · doi:10.1111/j.1365-3016.2006.00765.x · Cited by 51 · see citing works
Hilgers, T. W., Daly, K. D., PREBIL, A. M., & Sk, H. (1992) · PubMed · Cited by 45 · see citing works
Bourne, T., Hagstrbm, H. G., Granberg, S., Josefsson, B., Hahlin, M., Hellberg, P., Hamberger, L., & Collins, W. P. (1996) · Human Reproduction · doi:10.1093/humrep/11.2.369 · Cited by 43 · see citing works
Pearlstone, A. C., & Surrey, E. S. (1994) · PubMed · Cited by 28 · see citing works
Robinson, J. E., & Ellis, J. E. (2007) · Current Medical Research and Opinion · doi:10.1185/030079906x162863 · Cited by 25 · see citing works
Potential Fertility — Defining the Window of Opportunity
Spieler, J., & Collins, W. P. (2001) · Journal of International Medical Research · doi:10.1177/14732300010290s102 · Cited by 15 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Lundsberg, L. S., Pal, L., Gariepy, A. M., Xu, X. J., Chu, M. C., & Illuzzi, J. L. (2014) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.12.006 · Cited by 162 · see citing works
Roos, J., Johnson, S., Weddell, S., Godehardt, E., Schiffner, J., Freundl, G., & Gnoth, C. (2015) · The European Journal of Contraception & Reproductive Health Care · doi:10.3109/13625187.2015.1048331 · Cited by 126 · see citing works
Self-citationCan apps and calendar methods predict ovulation with accuracy?
Johnson, S., Marriott, L., & Zinaman, M. (2018) · Current Medical Research and Opinion · doi:10.1080/03007995.2018.1475348 · Cited by 115 · see citing works
Real-life insights on menstrual cycles and ovulation using big data
Soumpasis, I., Grace, B., & Johnson, S. (2020) · Human Reproduction Open · doi:10.1093/hropen/hoaa011 · Cited by 76 · see citing works
Self-identification of the clinical fertile window and the ovulation period
Écochard, R., Duterque, O., Leiva, R. A., Bouchard, T. P., & Pilar Vigil, P. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.01.031 · Cited by 73 · see citing works
Johnson, S., Weddell, S., Godbert, S., Freundl, G., Roos, J., & Gnoth, C. (2015) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2014-1087 · Cited by 61 · see citing works
Efficacy of Achieving Pregnancy with Fertility-Focused Intercourse
Mu, Q., & Fehring, R. J. (2013) · MCN The American Journal of Maternal/Child Nursing · doi:10.1097/nmc.0b013e3182a76b88 · Cited by 43 · see citing works
Home ovulation tests and stress in women trying to conceive: a randomized controlled trial
Tiplady, S., Jones, G. L., Campbell, M. J., Johnson, S., & Ledger, W. J. (2012) · Human Reproduction · doi:10.1093/humrep/des372 · Cited by 42 · see citing works
Johnson, S., Stanford, J. B., Warren, G., Bond, S., Bench-Capon, S., & Zinaman, M. J. (2019) · Journal of Women s Health · doi:10.1089/jwh.2019.7850 · Cited by 34 · see citing works
Human chorionic gonadotropin as a measure of pregnancy duration
Larsen, J. W., Buchanan, P. D., Johnson, S., Godbert, S., & Zinaman, M. J. (2013) · International Journal of Gynecology & Obstetrics · doi:10.1016/j.ijgo.2013.05.028 · Cited by 29 · see citing works
Prediction of ovulation: new insight into an old challenge
Maman, E., Adashi, E. Y., Baum, M., & Hourvitz, A. (2023) · Scientific Reports · doi:10.1038/s41598-023-47241-2 · Cited by 26 · see citing works
Porucznik, C. A., Cox, K. J., Schliep, K. C., & Stanford, J. B. (2014) · BMC Women s Health · doi:10.1186/1472-6874-14-4 · Cited by 25 · see citing works
Oral contraceptives modulate the muscle metaboreflex in healthy young women
Parmar, H. R., Sears, J., Molgat‐Seon, Y., McCulloch, C. L., McCracken, L., Brown, C. V., Sheel, A. W., & Dominelli, P. B. (2017) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2017-0482 · Cited by 25 · see citing works
Validation of urinary reproductive hormone measurements using a novel smartphone connected reader
Pattnaik, S., Das, D., & Venkatesan, V. A. (2023) · Scientific Reports · doi:10.1038/s41598-023-36539-w · Cited by 18 · see citing works
Wegrzynowicz, A. K., Beckley, A., Eyvazzadeh, A. D., Levy, G., Park, J., & Klein, J. (2022) · Medicina · doi:10.3390/medicina58121853 · Cited by 17 · see citing works
Righarts, A., Dickson, N. P., Parkin, L., & Gillett, W. R. (2017) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.12606 · Cited by 17 · see citing works
Women’s experiences of ovulation testing: a qualitative analysis
Jones, G. L., Carlton, J., Weddell, S., Johnson, S., & Ledger, W. J. (2015) · Reproductive Health · doi:10.1186/s12978-015-0103-y · Cited by 14 · see citing works
Using Hormone Data and Age to Pinpoint Cycle Day within the Menstrual Cycle
Hills, E., Woodland, M. B., & Divaraniya, A. A. (2023) · Medicina · doi:10.3390/medicina59071348 · Cited by 12 · see citing works
Timed intercourse for couples trying to conceive
Gibbons, T., Reavey, J. J., Georgiou, E. X., & Becker, C. M. (2023) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011345.pub3 · Cited by 12 · see citing works
Hohmann‐Marriott, B. E., Williams, T., & Girling, J. E. (2023) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.13781 · Cited by 7 · see citing works
Gayatri, M., Utomo, B., Budiharsana, M. P., & Dasvarma, G. (2022) · PLoS ONE · doi:10.1371/journal.pone.0264318 · Cited by 6 · see citing works
Johnson, S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820050-6.00010-2 · Cited by 5 · see citing works
Johnson, S., Bond, S., Grace, B., & Marriott, L. (2022) · Women s Health Reports · doi:10.1089/whr.2021.0102 · Cited by 5 · see citing works
Implementation of a safer conception programme for HIV-affected men and women in rural Uganda
Matthews, L. T., Owembabazi, M., Tukwasibwe, D., Najjuma, A., Muyindike, W. R., Tumwine, J. M., Hornstein, B. D., Bassler, J. R., Long, D., Gill, E. S., et al. (2024) · Global Public Health · doi:10.1080/17441692.2024.2342023 · Cited by 4 · see citing works
Pedersen, E. S., Mikkelsen, E. M., Sørensen, H. T., Hatch, E. E., Wise, L. A., Rothman, K. J., Stanford, J. B., & Laursen, A. S. D. (2024) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.13108 · Cited by 4 · see citing works
Pattnaik, S., Das, D., & Venkatesan, V. A. (2021) · medRxiv · doi:10.1101/2021.05.11.21257023 · Cited by 2 · see citing works
β-HCG Level as a Predictive Marker of Pregnancy Progression or Retrogression
Simeon, G. G., Ezejimofor, M., & Cleston, O. N. (2021) · Open Journal of Obstetrics and Gynecology · doi:10.4236/ojog.2021.116066 · Cited by 1 · see citing works
Natürliche Familienplanung bei Kinderwunsch und Subfertilität
Raith-Paula, E., & Frank‐Herrmann, P. (2020) · Springer eBooks · doi:10.1007/978-3-662-59311-0_11 · Cited by 1 · see citing works
Zyklusformen im Leben einer Frau
Raith-Paula, E., & Frank‐Herrmann, P. (2020) · Springer eBooks · doi:10.1007/978-3-662-59311-0_9 · Cited by 1 · see citing works
Zyklusformen im Leben einer Frau
Raith-Paula, E., Frank‐Herrmann, P., Freundl, G., & Strowitzki, T. (2013) · Springer eBooks · doi:10.1007/978-3-642-29784-7_9
Zhu, Y., Xi, Q., Li, Z., Dai, R., Lv, X., & Yu, Y. (2025) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.70127 · Cited by 1 · see citing works
Yadav, R., & Dutta, N. (2026) · Middle East Fertility Society Journal · doi:10.1186/s43043-026-00369-3
- Authors
- Zinaman, M., Johnson, S., Ellis, J., & Ledger, W.
- Affiliations
- Tufts University (US)
- SPD Swiss Precision Diagnostics Development Co. Ltd BedfordUK
- Alere International CranfieldUK
- Royal Hospital for Women (AU)
- Corresponding author
- Johnson, Sarah
- Venue
- Current Medical Research and Opinion
- Publisher
- Informa Healthcare
- Published
- 2012-04-18
- Volume
- 28
- Issue
- 5
- Pages
- 749-754
- ISSN
- 0300-7995 (ISSN-L)
- 1473-4877
- OpenAlex
- W1995044351
- Cited by
- 33
- References
- 22
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 5 · 2022: 3 · 2021: 2 · 2020: 4 · 2019: 2 · 2018: 1 · 2017: 2 · 2015: 4 · 2014: 2 · 2013: 3 · 2012: 1
- FWCI
- 3.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Medical Research and Opinion (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Health and Contraception
- Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Reproductive Physiology in Livestock
- Keywords
- fertility awareness, fertile window, luteinizing hormone, timed intercourse, conception
- MeSH terms
- Adolescent, Adult, Coitus, Female, Fertilization, Humans, Health Knowledge, Attitudes, Practice, Luteinizing Hormone, Menstrual Cycle, Middle Aged, Ovulation Detection, Perception, Pregnancy, Prospective Studies, Cohort Studies, Urinalysis, Ovulation Prediction, Young Adult
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