Cited by 471Meta-analysis and systematic reviewsQualitative Research Methods and ApplicationsDelphi Technique in Research

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A worked example of “best fit” framework synthesis: a systematic review of views concerning the taking of some potential chemopreventive agents

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Carroll, Christopher, Booth, Andrew, Cooper, Katy·2011·BMC Medical Research Methodology

DOI 10.1186/1471-2288-11-29PMC PMC3068987

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Abstract

BACKGROUND: A variety of different approaches to the synthesis of qualitative data are advocated in the literature. The aim of this paper is to describe the application of a pragmatic method of qualitative evidence synthesis and the lessons learned from adopting this "best fit" framework synthesis approach. METHODS: An evaluation of framework synthesis as an approach to the qualitative systematic review of evidence exploring the views of adults to the taking of potential agents within the context of the primary prevention of colorectal cancer. RESULTS: Twenty papers from North America, Australia, the UK and Europe met the criteria for inclusion. Fourteen themes were identified a priori from a related, existing conceptual model identified in the literature, which were then used to code the extracted data. Further analysis resulted in the generation of a more sophisticated model with additional themes. The synthesis required a combination of secondary framework and thematic analysis approaches and was conducted within a health technology assessment timeframe. CONCLUSION: The novel and pragmatic "best fit" approach to framework synthesis developed and described here was found to be fit for purpose. Future research should seek to test further this approach to qualitative data synthesis.

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Figure 1 A priori themes reflecting people's views about taking potential chemopreventive agents, derived from Huffman 2002[16].CC BY · PubMed Central

Figure 2 Conceptual model to describe views and experiences of adults concerning the taking of potential chemoprevention agents.CC BY · PubMed Central

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Research works printed but not linked: 2

Grayson L, Gomersall A: A difficult business: finding the evidence for social science reviews. ESRC UK Centre for Evidence Based Policy and Practice. Working paper 19. 2003
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Authors: Carroll, C., Booth, A., & Cooper, K.
Affiliations: University of Sheffield (GB)
Corresponding author: Carroll, Christopher
ORCID: Carroll, Christopher
Booth, Andrew
Cooper, Katy
Venue: BMC Medical Research Methodology
Publisher: Springer Science and Business Media LLC
Published: 2011-03-16
Volume: 11
Issue: 1
Pages: 29-29
ISSN: 1471-2288 (ISSN-L)
DOI: 10.1186/1471-2288-11-29
PMC: PMC3068987
OpenAlex: W2068075745
Cited by: 461
References: 34
Citations by year: 2026: 53 · 2025: 31 · 2024: 51 · 2023: 54 · 2022: 35 · 2021: 58 · 2020: 40 · 2019: 21 · 2018: 27 · 2017: 20 · 2016: 22 · 2015: 12 · 2014: 6 · 2013: 15 · 2012: 14
FWCI: 2.90
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/2.0 (tdm)
Locations: BMC Medical Research Methodology (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (acceptedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics: Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
Social Sciences › Education › Qualitative Research Methods and Applications
Social Sciences › Sociology and Political Science › Delphi Technique in Research
Keywords: qualitative evidence synthesis, chemopreventive agents, patient perspectives, conceptual model, thematic analysis, health technology assessment
MeSH terms: Adult, Evaluation Studies as Topic, Humans, Models, Psychological, Research Design, Colorectal Neoplasms, Anticarcinogenic Agents, Chemoprevention

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A worked example of “best fit” framework synthesis: a systematic review of views concerning the taking of some potential chemopreventive agents

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