The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Validity of a novel computerized cognitive battery for mild cognitive impairment
Open accessAbstract
BACKGROUND: The NeuroTrax Mindstreams computerized cognitive assessment system was designed for widespread clinical and research use in detecting mild cognitive impairment (MCI). However, the capability of Mindstreams tests to discriminate elderly with MCI from those who are cognitively healthy has yet to be evaluated. Moreover, the comparability between these tests and traditional neuropsychological tests in detecting MCI has not been examined. METHODS: A 2-center study was designed to assess discriminant validity of tests in the Mindstreams Mild Impairment Battery. Participants were 30 individuals diagnosed with MCI, 29 with mild Alzheimer's disease (AD), and 39 healthy elderly. Testing was with the Mindstreams battery and traditional neuropsychological tests. Receiver operating characteristic (ROC) analysis was used to examine the ability of Mindstreams and traditional measures to discriminate those with MCI from cognitively healthy elderly. Between-group comparisons were made (Mann-Whitney U test) between MCI and healthy elderly and between MCI and mild AD groups. RESULTS: Mindstreams outcome parameters across multiple cognitive domains significantly discriminated among MCI and healthy elderly with considerable effect sizes (p < 0.05). Measures of memory, executive function, visual spatial skills, and verbal fluency discriminated best, and discriminability was at least comparable to that of traditional neuropsychological tests in these domains. CONCLUSIONS: Mindstreams tests are effective in detecting MCI, providing a comprehensive profile of cognitive function. Further, the enhanced precision and ease of use of these computerized tests make the NeuroTrax system a valuable clinical tool in the identification of elderly at high risk for dementia.
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“Scores were normalized to an IQ-like scale (mean = 100, SD = 15), adjusted for age and education, based on a normative database from over 10 research sites (16, 17).”
From Hyperbaric oxygen therapy improves post-concussion symptoms in adults with childhood traumatic brain injury: a retrospective cohort study (2025) · cites this paper as [16]
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“To minimize learning effects, equivalent but non-identical test versions were used for pre-and post-HBOT evaluations. These have demonstrated high test–retest reliability and minimal practice effects (16).”
From Hyperbaric oxygen therapy improves post-concussion symptoms in adults with childhood traumatic brain injury: a retrospective cohort study (2025) · cites this paper as [16]
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Mild Cognitive Impairment: Clinical Characterization and Outcome
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Petersen, R. C., Stevens, J. C., Ganguli, M., Tangalos, E. G., Cummings, J. L., & DeKosky, S. T. (2001) · Neurology · doi:10.1212/wnl.56.9.1133 · Cited by 2,065
Mild cognitive impairment in the elderly: Predictors of dementia
Flicker, C., Ferris, S. H., & Reisberg, B. (1991) · Neurology · doi:10.1212/wnl.41.7.1006 · Cited by 838
Neuropsychological detection and characterization of preclinical Alzheimer’s disease
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Visual memory predicts Alzheimer's disease more than a decade before diagnosis
Kawas, C. H., Corrada, M. M., Brookmeyer, R., Morrison, A., Resnick, S. M., Zonderman, A. B., & Arenberg, D. (2003) · Neurology · doi:10.1212/01.wnl.0000055813.36504.bf · Cited by 247
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GUALTIERI, C., & JOHNSON, L. (2006) · Archives of Clinical Neuropsychology · doi:10.1016/j.acn.2006.05.007 · Cited by 873
Language performance in Alzheimer's disease and mild cognitive impairment: A comparative review
Taler, V., & Phillips, N. A. (2008) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390701550128 · Cited by 529
Status of computerized cognitive testing in aging: a systematic review
Wild, K., Howieson, D., Webbe, F., Seelye, A., & Kaye, J. (2008) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2008.07.003 · Cited by 436
Computerized Cognitive Testing for Older Adults: A Review
Zygouris, S., & Tsolaki, M. (2015) · American Journal of Alzheimer's Disease & Other Dementias® · doi:10.1177/1533317514522852 · Cited by 272
Use of the Virtual Action Planning Supermarket for the Diagnosis of Mild Cognitive Impairment
Werner, P., Rabinowitz, S., Klinger, E., Korczyn, A. D., & Josman, N. (2009) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000204915 · Cited by 135
Metadata
- Authors
- Dwolatzky, T., Whitehead, V., Doniger, G. M., Simon, E. S., Schweiger, A., Jaffe, D., & Chertkow, H.
- Venue
- BMC Geriatrics
- Published
- 2003-11-02
- Volume
- 3
- Issue
- 1
- Pages
- 4-4
- ISSN
- 1471-2318 (ISSN-L)
- OpenAlex
- W1481804282
- Cited by
- 314
- References
- 7
- FWCI
- 3.50
- Type
- journal article
- Language
- en
- Open access
- gold
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- Dwolatzky, T., Whitehead, V., Doniger, G. M., Simon, E. S., Schweiger, A., Jaffe, D., & Chertkow, H. (2003). Validity of a novel computerized cognitive battery for mild cognitive impairment. BMC Geriatrics. https://doi.org/10.1186/1471-2318-3-4
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