Gene polymorphisms of superoxide dismutases and catalase in diabetes mellitus
Open accessAbstract
BACKGROUND: Reactive oxygen species generated by hyperglycaemia modify structure and function of lipids, proteins and other molecules taking part in chronic vascular changes in diabetes mellitus (DM). Low activity of scavenger enzymes has been observed in patients with DM. Protective role of scavenger enzymes may be deteriorated by oxidative stress. This study was undertaken to investigate the association between gene polymorphisms of selected antioxidant enzymes and vascular complications of DM. RESULTS: Significant differences in allele and genotype distribution among T1DM, T2DM and control persons were found in SOD1 and SOD2 genes but not in CAT gene (p < 0,01). Serum SOD activity was significantly decreased in T1DM and T2DM subjects compared to the control subjects (p < 0,05). SOD1 and SOD2 polymorphisms may affect SOD activity. Serum SOD activity was higher in CC than in TT genotype of SOD2 gene (p < 0,05) and higher in AA than in CC genotype of SOD1 gene (p < 0,05). Better diabetes control was found in patients with CC than with TT genotype of SOD2 gene. Significantly different allele and genotype frequencies of SOD2 gene polymorphism were found among diabetic patients with macroangiopathy and those without it. No difference was associated with microangiopathy in all studied genes. CONCLUSION: The results of our study demonstrate that oxidative stress in DM can be accelerated not only due to increased production of ROS caused by hyperglycaemia but also by reduced ability of antioxidant defense system caused at least partly by SNPs of some scavenger enzymes.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Heightened mitochondrial ROS production attenuates insulin signaling and promotes insulin resistance.
“It is well established that heightened mitochondrial ROS production attenuates insulin signaling and promotes insulin resistance (12–14, 45).”
From Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance (2021) · cites this paper as [45]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Free radicals and antioxidants in normal physiological functions and human disease
Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T. D., Mazur, M., & Telser, J. (2007) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2006.07.001 · Cited by 14,269 · see citing works
McCord, J. M., & Fridovich, I. (1969) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63504-5 · Cited by 12,952 · see citing works
Diabetes, oxidative stress, and antioxidants: A review
Maritim, A. C., Sanders, R. A., & Watkins, J. B. (2003) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.10058 · Cited by 3,128 · see citing works
Zelko, I. N., Mariani, T. J., & Folz, R. J. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00905-x · Cited by 2,212 · see citing works
Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
Rolo, A. P., & Palmeira, C. M. (2006) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2006.01.003 · Cited by 1,007 · see citing works
Oxidative stress and the use of antioxidants in diabetes: Linking basic science to clinical practice
Johansen, J. S., Harris, A. K., Rychly, D. J., & Ergul, A. (2005) · Cardiovascular Diabetology · doi:10.1186/1475-2840-4-5 · Cited by 1,003 · see citing works
Vascular protection: superoxide dismutase isoforms in the vessel wall.
Faraci, F., & Didion, S. (2004) · Arteriosclerosis, Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000133604.20182.cf · Cited by 528 · see citing works
Shimoda‐Matsubayashi, S., Matsumine, H., Kobayashi, T., Nakagawa-Hattori, Y., Shimizu, Y., & Mizuno, Y. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.1394 · Cited by 498 · see citing works
Mortality Trends in Men and Women with Diabetes, 1971 to 2000
Gregg, E. W., Gu, Q., Cheng, Y. J., Narayan, K. M. V., & Cowie, C. C. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-3-200708070-00167 · Cited by 463 · see citing works
Mitochondrial reactive oxygen species-mediated signaling in endothelial cells
Zhang, D. X., & Gutterman, D. D. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01283.2006 · Cited by 432 · see citing works
Nishikawa, T., & Araki, E. (2007) · Antioxidants & Redox Signaling · doi:10.1089/ars.2006.1458 · Cited by 391 · see citing works
AGE, RAGE, and ROS in Diabetic Nephropathy
Tan, A. L. Y., Forbes, J. M., & Cooper, M. E. (2007) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2007.01.006 · Cited by 369 · see citing works
Forsberg, L. M., Lyrenäs, L., Morgenstern, R., & Fairé, U. D. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00487-1 · Cited by 284 · see citing works
Prognostic Stratification of Patients with Left-Sided Endocarditis Determined at Admission
Román, J. A. S., López, J., Vilacosta, I., Luaces, M., Sarriá, C., Revilla, A., Ronderos, R., Stoermann, W., Gómez, I., & Fernández‐Avilés, F. (2007) · The American Journal of Medicine · doi:10.1016/j.amjmed.2006.05.071 · Cited by 209 · see citing works
Oxidative stress, AGE, and atherosclerosis
Schleicher, E., & Friess, U. (2007) · Kidney International · doi:10.1038/sj.ki.5002382 · Cited by 201 · see citing works
Oxidative Enzymopathies and Vascular Disease
Leopold, J. A., & Loscalzo, J. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000163846.51473.09 · Cited by 188 · see citing works
Reactive Oxygen Species in Vascular Wall
Yung, L., Leung, F. S. K., Yao, X., Chen, Z., & Huang, Y. (2006) · Cardiovascular & Haematological Disorders - Drug Targets · doi:10.2174/187152906776092659 · Cited by 188 · see citing works
Song, F., Jia, W., Yao, Y., Hu, Y., Lei, L., Lin, J. M., Sun, X., & Liu, L. (2007) · Clinical Science · doi:10.1042/cs20060323 · Cited by 183 · see citing works
Nomiyama, T., Tanaka, Y., Piao, L., Nagasaka, K., Sakai, K., Ogihara, T., Nakajima, K., Watada, H., & Kawamori, R. (2003) · Journal of Human Genetics · doi:10.1007/s100380300021 · Cited by 110 · see citing works
Pathogenic superoxide dismutase structure, folding, aggregation and turnover
Hart, P. J. (2006) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2006.02.034 · Cited by 100 · see citing works
A polymorphism in the promoter region of catalase is associated with blood pressure levels
Jiang, Z., Akey, J. M., Shi, J., Xiong, M., Wang, Y., Shen, Y., Xu, X., Chen, H., Wu, H., Xiao, J., et al. (2001) · Human Genetics · doi:10.1007/s004390100553 · Cited by 99 · see citing works
Ukkola, O. H., Erkkilä, P. H., Savolainen, M. J., & Kesäniemi, Y. A. (2001) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2001.00828.x · Cited by 96 · see citing works
Nemoto, M., Nishimura, R., Sasaki, T., Hiki, Y., Miyashita, Y., Nishioka, M., Fujimoto, K., Sakuma, T., Ohashi, T., Fukuda, K., et al. (2007) · Cardiovascular Diabetology · doi:10.1186/1475-2840-6-23 · Cited by 86 · see citing works
Pathophysiological mechanisms of diabetic angiopathy
Hammes, H. (2003) · Journal of Diabetes and its Complications · doi:10.1016/s1056-8727(02)00275-1 · Cited by 84 · see citing works
Shimoda‐Matsubayashi, S., Hattori, T., Matsumine, H., Shinohara, A., Yoritaka, A., Mori, H., Kondo, T., Chiba, M., & Mizuno, Y. (1997) · Neurology · doi:10.1212/wnl.49.5.1257 · Cited by 74 · see citing works
Chistyakov, D. A., Savostyanov, K. V., Zotova, E., & Nosikov, V. V. (2001) · BMC Medical Genetics · doi:10.1186/1471-2350-2-4 · Cited by 67 · see citing works
Lee, S. J., Choi, M. G., Kim, D. S., & Kim, T. W. (2005) · Metabolism · doi:10.1016/j.metabol.2005.04.030 · Cited by 59 · see citing works
Nahon, P., Sutton, A., Pessayre, D., Rufat, P., Degoul, F., Ganne‐Carrié, N., Ziol, M., Charnaux, N., Nkontchou, G., Trinchet, J., et al. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(04)00718-9 · Cited by 57 · see citing works
Optimizing Cardiovascular Outcomes in Diabetes Mellitus
Sobel, B. E. (2007) · The American Journal of Medicine · doi:10.1016/j.amjmed.2007.07.002 · Cited by 56 · see citing works
Two functional variants of the superoxide dismutase genes in Finnish families with asthma
Kinnula, V. L. (2004) · Thorax · doi:10.1136/thorax.2003.005611 · Cited by 55 · see citing works
Lee, S. J., & Choi, M. G. (2006) · Metabolism · doi:10.1016/j.metabol.2006.08.011 · Cited by 45 · see citing works
Chistiakov, D. A., Savostyanov, K. V., Turakulov, R. I., Титович, Е. В., Zilberman, L. I., Кураева, Т. Л., Dedov, I. I., & Nosikov, V. V. (2004) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.442 · Cited by 38 · see citing works
Pask, R., Cooper, J. D., Walker, N. M., Nutland, S. L., Hutchings, J., Dunger, D. B., Nejentsev, S., & Todd, J. A. (2006) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.628 · Cited by 36 · see citing works
Molecular Targets of Diabetic Vascular Complications and Potential New Drugs
ROS, R. D., Assaloni, R., & Ceriello, A. (2005) · Current Drug Targets · doi:10.2174/1389450054021855 · Cited by 27 · see citing works
Sáez, M. E., Grilo, A., Morón, F. J., Manzano, L., Martinez-Larrad, M. T., González‐Pérez, A., Serrano-Hernando, F. J., Ruiz, A., Ramírez‐Lorca, R., & Serrano‐Ríos, M. (2008) · Cardiovascular Diabetology · doi:10.1186/1475-2840-7-23 · Cited by 25 · see citing works
Genetics of macrovascular complications in diabetes
Fumeron, F., Reis, A. F., & Velho, G. (2006) · Current Diabetes Reports · doi:10.1007/s11892-006-0028-5 · Cited by 13 · see citing works
The molecular basis of diabetic microangiopathy.
Mokini, Z., & Chiarelli, F. (2007) · PubMed · Cited by 13 · see citing works
Glycaemic control in critically ill patients with cardiovascular disease
Wade, A. O., & Cordingley, J. J. (2006) · Current Opinion in Critical Care · doi:10.1097/01.ccx.0000244123.39247.b9 · Cited by 9 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Manganese Superoxide Dismutase and Oxidative Stress Modulation
Bresciani, G., da Cruz, I. B. M., & González‐Gallego, J. (2015) · Advances in clinical chemistry · doi:10.1016/bs.acc.2014.11.001 · Cited by 285 · see citing works
Gusti, A. M. T., Qusti, S. Y., Alshammari, E. M., Toraih, E. A., & Fawzy, M. S. (2021) · Antioxidants · doi:10.3390/antiox10040595 · Cited by 238 · see citing works
Oxidative risk for atherothrombotic cardiovascular disease
Leopold, J. A., & Loscalzo, J. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.09.009 · Cited by 216 · see citing works
Relationships between single nucleotide polymorphisms of antioxidant enzymes and disease
Crawford, A., Fassett, R. G., GERAGHTY, D. P., Kunde, D., Ball, M. J., Robertson, I. K., & Coombes, J. S. (2012) · Gene · doi:10.1016/j.gene.2012.04.011 · Cited by 184 · see citing works
Human Catalase, Its Polymorphisms, Regulation and Changes of Its Activity in Different Diseases
Kodydková, J., Vávřová, L., Kocik, M., & Žák, A. (2014) · Folia Biologica · doi:10.14712/fb2014060040153 · Cited by 158 · see citing works
Reactive metabolites and antioxidant gene polymorphisms in Type 2 diabetes mellitus
Banerjee, M., & Vats, P. (2013) · Redox Biology · doi:10.1016/j.redox.2013.12.001 · Cited by 141 · see citing works
Two Tales of Antioxidant Enzymes on β Cells and Diabetes
Lei, X. G., & Vatamaniuk, M. Z. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3416 · Cited by 130 · see citing works
SOD1 Transcriptional and Posttranscriptional Regulation and Its Potential Implications in ALS
Milani, P., Gagliardi, S., Cova, E., & Cereda, C. (2011) · Neurology Research International · doi:10.1155/2011/458427 · Cited by 129 · see citing works
Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
Xirouchaki, C. E., Jia, Y., McGrath, M. J., Greatorex, S., Tran, M., Merry, T. L., Hong, D., Eramo, M. J., Broome, S. C., Woodhead, J. S. T., et al. (2021) · Science Advances · doi:10.1126/sciadv.abl4988 · Cited by 107 · see citing works
The copper‐zinc superoxide dismutase activity in selected diseases
Lewandowski, Ł., Kepinská, M., & Milnerowicz, H. (2018) · European Journal of Clinical Investigation · doi:10.1111/eci.13036 · Cited by 98 · see citing works
Mao, C., Yuan, J.-Q., Lv, Y.-B., Gao, X., Yin, Z.-X., Kraus, V. B., Luo, J.-S., Chei, C.-L., Matchar, D. B., Zeng, Y., et al. (2019) · BMC Geriatrics · doi:10.1186/s12877-019-1109-z · Cited by 94 · see citing works
Kupsco, A. J., Kioumourtzoglou, M., Just, A. C., Amarasiriwardena, C. J., Estrada‐Gutiérrez, G., Cantoral, A., Sanders, A. P., Braun, J. M., Svensson, K., Brennan, K. J. M., et al. (2018) · Epidemiology · doi:10.1097/ede.0000000000000962 · Cited by 89 · see citing works
Kędziora–Kornatowska, K., Szewczyk‐Golec, K., Kozakiewicz, M., Pawluk, H., Czuczejko, J., Kornatowski, T., Bartosz, G., & Kędziora, J. (2009) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2009.00666.x · Cited by 87 · see citing works
The MnSOD Ala16Val SNP: Relevance to human diseases and interaction with environmental factors
Bresciani, G., da Cruz, I. B. M., Fernández, J. A. D. P., Cuevas, M. J., & González‐Gallego, J. (2013) · Free Radical Research · doi:10.3109/10715762.2013.836275 · Cited by 84 · see citing works
U-Shaped Association between Plasma Manganese Levels and Type 2 Diabetes
Shan, Z., Chen, S., Sun, T., Luo, C., Guo, Y., Yu, X., Yang, W. Q., Hu, F. B., & Liu, L. (2016) · Environmental Health Perspectives · doi:10.1289/ehp176 · Cited by 81 · see citing works
Zhang, Y., Zhang, L., Sun, D., Li, Z., Wang, L., & Liu, P. (2011) · Europe PMC (PubMed Central) · Cited by 72 · see citing works
Oxidative stress and antioxidants in diabetes mellitus
Rafieian‐Kopaei, M., Ghasemi‐Dehnoo, M., Amini-Khoei, H., & Lorigooini, Z. (2020) · Asian Pacific Journal of Tropical Medicine · doi:10.4103/1995-7645.291036 · Cited by 71 · see citing works
Crawford, A., Fassett, R. G., Coombes, J. S., Kunde, D., Ahuja, K., Robertson, I. K., Ball, M. J., & GERAGHTY, D. P. (2011) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfq828 · Cited by 71 · see citing works
Tian, C., Fang, S., Du, X., & Jia, C. (2010) · Diabetologia · doi:10.1007/s00125-010-2004-5 · Cited by 70 · see citing works
Vats, P., Sagar, N., Singh, T. P., & Banerjee, M. (2014) · Free Radical Research · doi:10.3109/10715762.2014.971782 · Cited by 67 · see citing works
Pourvali, K., Abbasi, M., & Mottaghi, A. (2016) · Europe PMC (PubMed Central) · Cited by 67 · see citing works
Lewandowski, Ł., Kepinská, M., & Milnerowicz, H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21145069 · Cited by 64 · see citing works
Greatorex, S., Kaur, S., Xirouchaki, C. E., Goh, P. K., Wiede, F., Genders, A., Tran, M., Jia, Y., Raajendiran, A., Brown, W., et al. (2023) · Journal of Clinical Investigation · doi:10.1172/jci162533 · Cited by 50 · see citing works
The skin function: a factor of anti-metabolic syndrome
Zhou, S., Li, D., Zhou, Y., & Cao, J.-M. (2012) · Diabetology & Metabolic Syndrome · doi:10.1186/1758-5996-4-15 · Cited by 91 · see citing works
Hou, Y., Shi, Y., Han, B., Liu, X., Qiao, X., Qi, Y. A., & Wang, L. (2018) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfy021 · Cited by 54 · see citing works
Can we predict top‐level sports performance in power vs endurance events? A genetic approach
Buxens, A., Ruiz, J. R., Arteta, D., Artieda, M., Santiago, C., González‐Freire, M., Martínez, A., Tejedor, D., Lao, J. I., Gómez‐Gallego, F., et al. (2010) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.2009.01079.x · Cited by 53 · see citing works
Evaluation of gene polymorphisms in exercise-induced oxidative stress and damage
Akimoto, A. K., Miranda‐Vilela, A. L., Alves, P. C. Z., Pereira, L. C. D. S., Lordelo, G. S., Hiragi, C. D. O., da Silva, I. C. R., Grisólia, C. K., & Klautau‐Guimarães, M. D. N. (2010) · Free Radical Research · doi:10.3109/10715760903494176 · Cited by 53 · see citing works
Reactive oxygen species in diabetic nephropathy: friend or foe?
Bondeva, T., & Wolf, G. (2014) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfu037 · Cited by 53 · see citing works
Parameters of oxidative stress, DNA damage and DNA repair in type 1 and type 2 diabetes mellitus
Pácal, L., Varvařovská, J., Rušavý, Z., Lacigová, S., Štětina, R., Ráček, J., Pomahačová, R., Tanhäuserová, V., & Kaňková, K. (2011) · Archives of Physiology and Biochemistry · doi:10.3109/13813455.2010.551135 · Cited by 51 · see citing works
Kahl, V. F. S., da Silva, F. R., Alves, J., da Silva, G. F., Picinini, J., Dhillon, V. S., Fenech, M. F., de Souza, M. R., Dias, J. F., de Souza, C. T., et al. (2018) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2018.04.052 · Cited by 51 · see citing works
Wang, Y., Dai, G., Li, L., Liu, L., Jiang, L., Li, S., Liao, S., Wang, F., Du, W., & Li, Y. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.8137 · Cited by 49 · see citing works
Jones, D. A., Prior, S. L., Tang, T. S., Bain, S. C., Hurel, S. J., Humphries, S. E., & Stephens, J. W. (2010) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2010.07.009 · Cited by 48 · see citing works
Yin, J., Wang, X., Li, S., Zhu, Y., Chen, S., Li, P., Luo, C., Huang, Y., Li, X., Hu, X., et al. (2019) · Redox Biology · doi:10.1016/j.redox.2019.101172 · Cited by 47 · see citing works
Targeted antioxidant therapies in hyperglycemia-mediated endothelial dysfunction
de Haan, J. B. (2010) · Frontiers in Bioscience-Scholar · doi:10.2741/s182 · Cited by 47 · see citing works
Fischer, L. R., & Glass, J. D. (2009) · Acta Neuropathologica · doi:10.1007/s00401-009-0631-z · Cited by 46 · see citing works
Kang, L., Dai, C., Lustig, M. E., Bonner, J. S., Mayes, W. H., Mokshagundam, S., James, F. D., Thompson, C. S., Lin, C., Perry, C. G. R., et al. (2014) · Diabetes · doi:10.2337/db13-1845 · Cited by 46 · see citing works
Szczuko, M., Zapalowska-Chwyć, M., & Drozd, R. (2019) · Molecules · doi:10.3390/molecules24081508 · Cited by 45 · see citing works
Bounafaa, A., Berrougui, H., Ghalim, N., Nasser, B., Bagri, A., Moujahid, A., Ikhlef, S., Camponova, P., Yamoul, N., Simo, O. K., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0133719 · Cited by 44 · see citing works
Liu, Y., Xie, L., Zhao, J., Huang, X., Song, L., Luo, J., Ma, L., Li, S., & Qin, X. Y. (2015) · Medicine · doi:10.1097/md.0000000000000702 · Cited by 44 · see citing works
Mitochondrial Dysfunction in Individuals with Diabetic Kidney Disease: A Systematic Review
Flemming, N., Pernoud, L., Forbes, J. M., & Gallo, L. A. (2022) · Cells · doi:10.3390/cells11162481 · Cited by 40 · see citing works
Yeh, H.-L., Kuo, L., Sung, F.-C., & Yeh, C. (2018) · BioMed Research International · doi:10.1155/2018/5086869 · Cited by 39 · see citing works
Reactive metabolites and antioxidant gene polymorphisms in type 2 diabetes mellitus
Banerjee, M., & Vats, P. (2014) · Indian journal of human genetics · doi:10.4103/0971-6866.132747 · Cited by 38 · see citing works
Catalase polymorphisms and metabolic diseases
Hébert-Schuster, M., Fabre, E. E., & Nivet‐Antoine, V. (2012) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e328354a326 · Cited by 38 · see citing works
Novel Treatment of Neuroinflammation Against Low Back Pain by Soluble Fullerol Nanoparticles
Liu, Q., Jin, L., Mahon, B. H., Chordia, M. D., Shen, F. H., & Li, X. J. (2013) · Spine · doi:10.1097/brs.0b013e31828fc6b7 · Cited by 37 · see citing works
Lipoperoxidation and antioxidant capacity in patients with poorly controlled type 2 diabetes
Lodovici, M., Bigagli, E., Bardini, G., & Rotella, C. M. (2009) · Toxicology and Industrial Health · doi:10.1177/0748233709106464 · Cited by 37 · see citing works
Buraczyńska, M., Buraczyńska, K., Dragan, M., & Książek, A. (2016) · NeuroMolecular Medicine · doi:10.1007/s12017-016-8438-2 · Cited by 36 · see citing works
Sonkar, V. K., Eustes, A. S., Ahmed, A., Jensen, M. J., Solanki, M. V., Swamy, J., Kumar, R. K., Fidler, T. P., Houtman, J. C. D., Allen, B. G., et al. (2022) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.121.317735 · Cited by 34 · see citing works
Góth, L., Nagy, T., Kósa, Z., Fejes, Z., Bhattoa, H. P., Paragh, G., & Káplár, M. (2012) · Free Radical Research · doi:10.3109/10715762.2012.702899 · Cited by 34 · see citing works
Farawela, H. M., Khorshied, M. M., Shaheen, I. A. E.-M., Gouda, H. M., Nasef, A., Abulata, N. N., MAHMOUD, H. A. M. E. H., Zawam, H. M., & Mousa, S. M. (2012) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2012.04.007 · Cited by 33 · see citing works
Miranda‐Vilela, A. L., Alves, P. C. Z., Akimoto, A. K., Lordelo, G. S., Gonçalves, C. A., Grisólia, C. K., & Klautau-Guimarães, M. N. (2010) · Environmental Health · doi:10.1186/1476-069x-9-21 · Cited by 33 · see citing works
Oxidative Stress Genes, Antioxidants and Coronary Artery Disease in Type 2 Diabetes Mellitus
Tibaut, M., & Petrovi, D. (2016) · Cardiovascular & Hematological Agents in Medicinal Chemistry · doi:10.2174/1871525714666160407143416 · Cited by 33 · see citing works
Obafemi, T. O., Olasehinde, O. R., Olaoye, O. A., Jaiyesimi, K. F., Adewumi, F. D., Adewale, O. B., & Afolabi, B. A. (2020) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-020-00541-0 · Cited by 32 · see citing works
Wu, D., Chen, Y., Wan, X., Liu, D., Wen, Y., Chen, X., & Zhao, C. (2020) · Algal Research · doi:10.1016/j.algal.2020.102083 · Cited by 32 · see citing works
Ghattas, M. H., & Abo–Elmatty, D. M. (2012) · DNA and Cell Biology · doi:10.1089/dna.2012.1739 · Cited by 31 · see citing works
Kariž, S., Starčević, J. N., & Petrovič, D. (2012) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2012.07.003 · Cited by 31 · see citing works
Dutkiewicz, E., Domański, L., Pawlik, A., Bińczak‐Kuleta, A., Safranow, K., Ciechanowicz, A., Dziedziejko, V., Pietrzak-Nowacka, M., & Ciechanowski, K. (2010) · Archives of Medical Research · doi:10.1016/j.arcmed.2010.06.006 · Cited by 29 · see citing works
Kasznicki, J., Śliwińska, A., Kosmalski, M., Merecz-Sadowska, A., Majsterek, I., & Drzewoski, J. (2015) · Advances in Medical Sciences · doi:10.1016/j.advms.2015.10.006 · Cited by 29 · see citing works
Hernández‐Guerrero, C., Chávez, P. H., Romo‐Palafox, I., Blanco-Melo, G., Parra‐Carriedo, A., & Pérez‐Lizaur, A. B. (2016) · Archives of Medical Research · doi:10.1016/j.arcmed.2016.08.007 · Cited by 28 · see citing works
Panduru, N. M., Cimponeriu, D., Cruce, M., Ion, D. A., Moţa, E., Moța, M., Serafinceanu, C., Chivu, L. I., Panduru, M., Chivu, R. D., et al. (2010) · PubMed · Cited by 28 · see citing works
Ruiz-Sanz, J. I., Aurrekoetxea, I., Matorras, R., & Ruiz‐Larrea, M. B. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.11.022 · Cited by 27 · see citing works
Nutritional Supplements and Their Effect on Glucose Control
Lee, T., & Dugoua, J.-J. (2011) · Current Diabetes Reports · doi:10.1007/s11892-010-0175-6 · Cited by 28 · see citing works
Petrovič, D., & Peterlin, B. (2014) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2014.03.012 · Cited by 26 · see citing works
The Predisposition for Type 2 Diabetes Mellitus and Metabolic Syndrome
Zenoaga-Barbăroşie, C., BERCA, L.-M., Dimov, T. V., Toma, M., Nica, M., Alexiu-Toma, O. A., Ciornei, C., Albu, A. I., Nica, S., Nistor, C., et al. (2023) · Balkan Journal of Medical Genetics · doi:10.2478/bjmg-2023-0003 · Cited by 24 · see citing works
Houldsworth, A., Hodgkinson, A., Shaw, S. R., Millward, A. B., & Demaine, A. G. (2015) · Gene · doi:10.1016/j.gene.2015.04.006 · Cited by 23 · see citing works
Assessment of 193 Candidate Genes for Retinopathy in African Americans With Type 1 Diabetes
Roy, M. S. (2009) · Archives of Ophthalmology · doi:10.1001/archophthalmol.2009.48 · Cited by 23 · see citing works
Lewandowski, Ł., Urbanowicz, I., Kepinska, M., & Milnerowicz, H. (2021) · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · doi:10.1016/j.biopha.2021.111396 · Cited by 19 · see citing works
Gusti, A. M. T., Qusti, S. Y., Bahijri, S., Toraih, E. A., Bokhari, S., Attallah, S. M., Alzahrani, A., Alshehri, W. M., Alotaibi, H., & Fawzy, M. S. (2021) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s300525 · Cited by 24 · see citing works
Rajkumar, S., Vasavada, A. R., Praveen, M. R., Rajendran, A., Reddy, G. B., Tripathi, H., Ganatra, D. A., Arora, A. I., & Patel, A. R. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.13-11935 · Cited by 24 · see citing works
Kariž, S., Mankoč, S., & Petrovič, D. (2015) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2015.01.038 · Cited by 22 · see citing works
50-bp Ins/Del polymorphism of SOD1 is associated with increased risk of cardiovascular disease.
Eskandari‐Nasab, E., Kharazi-Nejad, E., Nakhaee, A., Afzali, M., Tabatabaei, S. P., Tirgarfakheri, K., & Hashemi, M. M. (2014) · PubMed · Cited by 21 · see citing works
Superoxide Dismutase and Catalase Genotypes in Pediatric Migraine Patients
Saygı, S., Erol, İ., Alehan, F., Yalçın, Y., Kubat, G., & Ataç, F. B. (2015) · Journal of Child Neurology · doi:10.1177/0883073815575366 · Cited by 20 · see citing works
Redox Biology in Adipose Tissue Physiology and Obesity
Yu, J., Qiu, J., Zhang, Z., Cui, X., Guo, W., Sheng, M., Gao, M., Wang, D., Xu, L., & Ma, X. (2023) · Advanced Biology · doi:10.1002/adbi.202200234 · Cited by 19 · see citing works
Karahalıl, B., Kesimci, E., Emerce, E., Gümüş, T., & Kanbak, O. (2010) · Molecular Biology Reports · doi:10.1007/s11033-010-0378-6 · Cited by 19 · see citing works
Saravani, S., Miri, H., Saravani, R., Yari, D., Nakhaee, A., & Mahjoubifard, M. (2015) · Molecular Genetics Microbiology and Virology · doi:10.3103/s0891416815040096 · Cited by 18 · see citing works
The role of base excision repair in pathogenesis of breast cancer in the Polish population
Cuchra, M., Mucha, B., Markiewicz, Ł., Przybyłowska-Sygut, K., Pytel, D., Jeziorski, A., Kordek, R., & Majsterek, I. (2015) · Molecular Carcinogenesis · doi:10.1002/mc.22436 · Cited by 17 · see citing works
Genetic polymorphism of antioxidant enzymes in eosinophilic and non-eosinophilic nasal polyposis
Akyiğit, A., Keleş, E., Etem, E., Ozercan, I., Akyol, H., Sakallioglu, O., Karlıdağ, T., Polat, C., Kaygusuz, İ., & Yalçın, Ş. (2016) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-016-4259-z · Cited by 18 · see citing works
The role of oxidative post-translational modifications in type 1 diabetes pathogenesis
Alhamar, G., Vinci, C., Franzese, V., Tramontana, F., Goux, N. L., Ludvigsson, J., Nissim, A., & Strollo, R. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1537405 · Cited by 16 · see citing works
Quirós-González, I., González‐Menéndez, P., Mayo, J. C., Hevia, D., Artime-Naveda, F., Fernández-Vega, S., Fernandez-Fernandez, M., Rodríguez‐González, P., Alonso, J. I. G., & Sainz, R. M. (2022) · Antioxidants · doi:10.3390/antiox11020313 · Cited by 16 · see citing works
Klen, J., Goričar, K., Janež, A., & Dolžan, V. (2015) · Personalized Medicine · doi:10.2217/pme.14.86 · Cited by 16 · see citing works
Kıdır, V., Uz, E., Yigit, A., Altuntaş, A., Yiğit, B., İnal, S., Uz, E., Sezer, M. T., & Yılmaz, H. R. (2016) · Renal Failure · doi:10.3109/0886022x.2015.1135468 · Cited by 16 · see citing works
Genetic Polymorphisms of Catalase and Glutathione Peroxidase-1 in Keratoconus.
Yari, D., Saravani, R., Saravani, S., Ebrahimian, K., & Galavi, H. R. (2018) · Europe PMC (PubMed Central) · Cited by 16 · see citing works
Polymorphisms in the FAS gene are associated with susceptibility to noise-induced hearing loss
Xu, S., Wang, B., Han, L., Pu, Y., Zhu, B., & Zhang, J. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-12028-9 · Cited by 16 · see citing works
Fernandes, R. C., Hasan, M., Gupta, H., Geetha, K., Rai, P. S., Hande, M., D’Souza, S. C., Adhikari, P., Brand, A. M., & Satyamoorthy, K. (2015) · Molecular Genetics and Genomics · doi:10.1007/s00438-014-0984-4 · Cited by 16 · see citing works
Nitrones reverse hyperglycemia-induced endothelial dysfunction in bovine aortic endothelial cells
Headley, C. A., DiSilvestro, D. J., Bryant, K. E., Hemann, C. F., Chen, C., Das, A. K., Ziouzenkova, O., Durand, G., & Villamena, F. A. (2016) · Biochemical Pharmacology · doi:10.1016/j.bcp.2016.01.005 · Cited by 16 · see citing works
Potential underlying genetic associations between keratoconus and diabetes mellitus
Ates, K. M., Estes, A. J., & Liu, Y. (2021) · Advances in Ophthalmology Practice and Research · doi:10.1016/j.aopr.2021.100005 · Cited by 15 · see citing works
Petrovič, D. (2013) · Clinical and Experimental Hypertension · doi:10.3109/10641963.2013.783051 · Cited by 15 · see citing works
Albeladi, F. I., Mostafa, M., Zayed, M. A., & Atta, H. M. (2022) · International Journal of General Medicine · doi:10.2147/ijgm.s367673 · Cited by 14 · see citing works
Oxidative Damage and Bronchial Asthma
Babušíková, E., Jurečeková, J., Evinová, A., Jeseňák, M., & Dobrot, D. (2012) · InTech eBooks · doi:10.5772/32132 · Cited by 13 · see citing works
Glutathione S-transferase and Catalase gene polymorphisms with Type 2 diabetes mellitus.
Vats, P., Chandra, H., & Banerjee, M. (2013) · Disease and Molecular Medicine · doi:10.5455/dmm.20131027101207 · Cited by 13 · see citing works
N, N. K., Angeline, T., Isabel, W., & Asirvatham, A. J. (2016) · Genetics Research International · doi:10.1155/2016/3787268 · Cited by 13 · see citing works
Ryu, D., Rahman, M. S., & Pang, M. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18091909 · Cited by 13 · see citing works
Oxidative stress gene polymorphisms may have an impact in the development of ischemic stroke
Karahalıl, B., Elkama, A., & Orhan, G. (2017) · The Journal of Gene Medicine · doi:10.1002/jgm.2947 · Cited by 13 · see citing works
Polonikov, A., Ivanov, V. P., Bogomazov, A. D., & Solodilova, M. A. (2015) · Biomeditsinskaya Khimiya · doi:10.18097/pbmc20156104427 · Cited by 12 · see citing works
Wang, Y., Dai, G., Wang, L., Shang, F., Jiang, L., Li, S., Huang, L., Xia, J., & Wei, H. (2019) · Genetic Testing and Molecular Biomarkers · doi:10.1089/gtmb.2019.0043 · Cited by 11 · see citing works
Darroudi, S., Tajbakhsh, A., Esmaily, H., Ghazizadeh, H., Zamani, P., Sadabadi, F., Tayefi, M., Tayefi, B., Fereydouni, N., Mouhebati, M., et al. (2019) · BioFactors · doi:10.1002/biof.1575 · Cited by 11 · see citing works
Pipal, K. V., Mamtani, M., Patel, A. A., Jaiswal, S. G., Jaisinghani, M. T., & Kulkarni, H. R. (2022) · Genes · doi:10.3390/genes13081298 · Cited by 11 · see citing works
Personalized sports nutrition: Role of nutrients in athletic performance
Sorrenti, V., Caudullo, G., Lucignano, F., Fortinguerra, S., Zusso, M., Giusti, P., & Buriani, A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816193-7.00018-x · Cited by 11 · see citing works
Abdul‐Maksoud, R. S., Fouad, R. A., Elsayed, T. G., Ibrahem, R. A. L., & Badawi, A. E. (2020) · The Journal of Gene Medicine · doi:10.1002/jgm.3192 · Cited by 11 · see citing works
Prevalence of Catalase (-21 A/T) Gene Variant in South Indian (Tamil) Population
Mary, A. L., N, N. K., Isabel, W., & Angeline, T. (2014) · BioMed Research International · doi:10.1155/2014/894237 · Cited by 10 · see citing works
Holbrook, O. T., Molligoda, B., Bushell, K. N., & Gobrogge, K. L. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.12.024 · Cited by 10 · see citing works
- Authors
- Flekac, M., Skrha, J., Hilgertova, J., Lacinova, Z., & Jarolimkova, M.
- Affiliations
- Charles University (CZ)
- Venue
- BMC Medical Genetics
- Published
- 2008-04-21
- Volume
- 9
- Issue
- 1
- Pages
- 30-30
- ISSN
- 1471-2350 (ISSN-L)
- PMC
- PMC2386118
- OpenAlex
- W2172261221
- Cited by
- 161
- References
- 38
- Citations by year
- 2026: 6 · 2025: 4 · 2024: 4 · 2023: 6 · 2022: 10 · 2021: 10 · 2020: 12 · 2019: 10 · 2018: 8 · 2017: 7 · 2016: 12 · 2015: 13 · 2014: 12 · 2013: 10 · 2012: 9
- FWCI
- 3.70
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Medical Genetics (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Glutathione Transferases and Polymorphisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Paraoxonase enzyme and polymorphisms
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Keywords
- superoxide dismutase, catalase, diabetes mellitus, type 1 diabetes, type 2 diabetes, oxidative stress, antioxidant enzymes, vascular complications, macroangiopathy, microangiopathy, reactive oxygen species, hyperglycemia, single nucleotide polymorphisms
- MeSH terms
- Superoxide Dismutase-1, Superoxide Dismutase 2, Adult, Aged, Catalase, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Angiopathies, Female, Humans, Male, Middle Aged, Risk Factors, Superoxide Dismutase, Oxidative Stress, Polymorphism, Single Nucleotide
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
