The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
The cost of relapse and the predictors of relapse in the treatment of schizophrenia
Open accessAbstract
BACKGROUND: To assess the direct cost of relapse and the predictors of relapse during the treatment of patients with schizophrenia in the United States. METHODS: Data were drawn from a prospective, observational, noninterventional study of schizophrenia in the United States (US-SCAP) conducted between 7/1997 and 9/2003. Patients with and without relapse in the prior 6 months were compared on total direct mental health costs and cost components in the following year using propensity score matching method. Baseline predictors of subsequent relapse were also assessed. RESULTS: Of 1,557 participants with eligible data, 310 (20%) relapsed during the 6 months prior to the 1-year study period. Costs for patients with prior relapse were about 3 times the costs for patients without prior relapse. Relapse was associated with higher costs for inpatient services as well as for outpatient services and medication. Patients with prior relapse were younger and had onset of illness at earlier ages, poorer medication adherence, more severe symptoms, a higher prevalence of substance use disorder, and worse functional status. Inpatient costs for patients with a relapse during both the prior 6 months and the follow-up year were 5 times the costs for patients with relapse during the follow-up year only. Prior relapse was a robust predictor of subsequent relapse, above and beyond information about patients' functioning and symptom levels. CONCLUSIONS: Despite the historical decline in utilization of psychiatric inpatient services, relapse remains an important predictor of subsequent relapse and treatment costs for persons with schizophrenia.
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Cites
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Self-citationPharmacy Data Identify Poorly Adherent Patients With Schizophrenia at Increased Risk for Admission
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The social and economic burden of treatment-resistant schizophrenia: a systematic literature review
Kennedy, J. L., Altar, C. A., Taylor, D. L., Degtiar, I., & Hornberger, J. C. (2014) · International Clinical Psychopharmacology · doi:10.1097/yic.0b013e32836508e6 · Cited by 392
Wang, R., Aung, M. S. H., Abdullah, S., Brian, R., Campbell, A. T., Choudhury, T., Hauser, M., Kane, J., Merrill, M., Scherer, E. A., et al. (2016) · Proceedings of the 2016 ACM International Joint Conference on Pervasive and Ubiquitous Computing · doi:10.1145/2971648.2971740 · Cited by 257
Definitions and drivers of relapse in patients with schizophrenia: a systematic literature review
Olivares, J. M., Sermon, J., Hemels, M., & Schreiner, A. (2013) · Annals of General Psychiatry · doi:10.1186/1744-859x-12-32 · Cited by 270
Clinical benefits and impact of early use of long‐acting injectable antipsychotics for schizophrenia
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Metadata
- Authors
- Ascher-Svanum, H., Zhu, B., Faries, D. E., Salkever, D., Slade, E. P., Peng, X., & Conley, R. R.
- Venue
- BMC Psychiatry
- Published
- 2010-01-07
- Volume
- 10
- Issue
- 1
- Pages
- 2-2
- ISSN
- 1471-244X (ISSN-L)
- OpenAlex
- W1989209269
- Cited by
- 275
- References
- 24
- FWCI
- 14.16
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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