Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition

Toledo, Jon B; Weiner, Michael W; Wolk, David A; Da, Xiao; Chen, Kewei; Arnold, Steven E; Jagust, William; Jack, Clifford; Reiman, Eric M; Davatzikos, Christos; Shaw, Leslie M; Trojanowski, John Q; for the Alzheimer’s Disease Neuroimaging Initiative

doi:10.1186/2051-5960-2-26

Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition

Based on previous studies, a preclinical classification for Alzheimer’s disease (AD) has been proposed. However, 1) specificity of the different neuronal injury (NI) biomarkers has not been studied, 2) subjects with subtle cognitive impairment but normal NI biomarkers (SCINIB) have not been inclu…