The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
NF-κB, stem cells and breast cancer: the links get stronger
Open accessAbstract
Self-renewing breast cancer stem cells are key actors in perpetuating tumour existence and in treatment resistance and relapse. The molecular pathways required for their maintenance are starting to be elucidated. Among them is the transcription factor NF-κB, which is known to play critical roles in cell survival, inflammation and immunity. Recent studies indicate that mammary epithelial NF-κB regulates the self-renewal of breast cancer stem cells in a model of Her2-dependent tumourigenesis. We will describe here the NF-κB-activating pathways that are involved in this process and in which progenitor cells this transcription factor is actually activated.
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Cites
NF-κB at the crossroads of life and death
Karin, M., & Lin, A. (2002) · Nature Immunology · doi:10.1038/ni0302-221 · Cited by 2,709
Nagata, Y., Lan, K.-H., Zhou, X., Tan, M., Esteva, F. J., Sahin, A. A., Klos, K. S., Li, P., Monia, B. P., Nguyen, N. T., et al. (2004) · Cancer Cell · doi:10.1016/j.ccr.2004.06.022 · Cited by 1,858
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Iliopoulos, D., Hirsch, H. A., & Struhl, K. (2009) · Cell · doi:10.1016/j.cell.2009.10.014 · Cited by 1,374
Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2
Wang, X., Belguise, K., Kersual, N., Kirsch, K. H., Mineva, N. D., Galtier, F., Chalbos, D., & Sonenshein, G. E. (2007) · Nature Cell Biology · doi:10.1038/ncb1559 · Cited by 209
Cited by
Challenges and Perspectives in the Treatment of Diabetes Associated Breast Cancer
Samuel, S. M., Varghese, E., Varghese, S., & Büsselberg, D. (2018) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2018.08.004 · Cited by 141
Kumar, M., Allison, D. F., Baranova, N. N., Wamsley, J. J., Katz, A. J., Bekiranov, S., Jones, D. R., & Mayo, M. W. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068597 · Cited by 107
Metadata
- Authors
- Shostak, K., & Chariot, A.
- Venue
- Breast Cancer Research
- Published
- 2011-07-26
- Volume
- 13
- Issue
- 4
- Pages
- 214-214
- ISSN
- 1465-5411 (ISSN-L)
- 1465-542X
- OpenAlex
- W2024893745
- Cited by
- 180
- References
- 5
- FWCI
- 3.83
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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