The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Liposome-based drug delivery in breast cancer treatment
Open accessAbstract
Drug delivery systems can in principle provide enhanced efficacy and/or reduced toxicity for anticancer agents. Long circulating macromolecular carriers such as liposomes can exploit the 'enhanced permeability and retention' effect for preferential extravasation from tumor vessels. Liposomal anthracyclines have achieved highly efficient drug encapsulation, resulting in significant anticancer activity with reduced cardiotoxicity, and include versions with greatly prolonged circulation such as liposomal daunorubicin and pegylated liposomal doxorubicin. Pegylated liposomal doxorubucin has shown substantial efficacy in breast cancer treatment both as monotherapy and in combination with other chemotherapeutics. Additional liposome constructs are being developed for the delivery of other drugs. The next generation of delivery systems will include true molecular targeting; immunoliposomes and other ligand-directed constructs represent an integration of biological components capable of tumor recognition with delivery technologies.
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Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery.
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Tumor targeting using anti-her2 immunoliposomes
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Cited by
Cancer nanotechnology: opportunities and challenges
Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558
Effect of pegylation on pharmaceuticals
Harris, J. M., & Chess, R. B. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1033 · Cited by 3,431
New developments in liposomal drug delivery
Pattni, B. S., Chupin, V. V., & Torchilin, V. P. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00046 · Cited by 1,600
The Smart Drug Delivery System and Its Clinical Potential
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Small particles, big impacts: A review of the diverse applications of nanofluids
Taylor, R., Coulombe, S., Otanicar, T., Phelan, P., Gunawan, A., Lv, W., Rosengarten, G., Prasher, R., & Tyagi, H. (2013) · Journal of Applied Physics · doi:10.1063/1.4754271 · Cited by 759
Metadata
- Authors
- Park, J. W.
- Venue
- Breast Cancer Research
- Published
- 2002-06
- Volume
- 4
- Issue
- 3
- Pages
- 95-9
- ISSN
- 1465-5411 (ISSN-L)
- 1465-542X
- OpenAlex
- W1492185019
- Cited by
- 469
- References
- 19
- FWCI
- 5.95
- Type
- journal article
- Language
- en
- Open access
- gold
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
