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The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists

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Huang, Da Wei, Sherman, Brad T, Tan, Qina, Collins, Jack R, Alvord, W Gregory, Roayaei, Jean, Stephens, Robert, Baseler, Michael W, Lane, H Clifford, Lempicki, Richard A·2007·Genome Biology
DOI 10.1186/gb-2007-8-9-r183
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Abstract

The DAVID Gene Functional Classification Tool http://david.abcc.ncifcrf.gov uses a novel agglomeration algorithm to condense a list of genes or associated biological terms into organized classes of related genes or biology, called biological modules. This organization is accomplished by mining the complex biological co-occurrences found in multiple sources of functional annotation. It is a powerful method to group functionally related genes and terms into a manageable number of biological modules for efficient interpretation of gene lists in a network context.

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Metadata

Authors
Huang, D. W., Sherman, B. T., Tan, Q., Collins, J. R., Alvord, W. G., Roayaei, J., Stephens, R., Baseler, M. W., Lane, H. C., & Lempicki, R. A.
Venue
Genome Biology
Publisher
Springer Science and Business Media LLC
Published
2007-09-04
Volume
8
Issue
9
Pages
R183-R183
ISSN
  • 1465-6906 (ISSN-L)
  • 1474-760X
DOI
10.1186/gb-2007-8-9-r183
OpenAlex
W2097795961
Cited by
2,479
References
2
FWCI
13.77
Type
journal article
Language
en
Open access
gold
Licence

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CoChat. (2026). Citation check: The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists. https://app.cochat.ai/papers/10.1186/gb-2007-8-9-r183
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Huang, D. W., Sherman, B. T., Tan, Q., Collins, J. R., Alvord, W. G., Roayaei, J., Stephens, R., Baseler, M. W., Lane, H. C., & Lempicki, R. A. (2007). The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists. Genome Biology. https://doi.org/10.1186/gb-2007-8-9-r183

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