The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
REAPR: a universal tool for genome assembly evaluation
Open accessAbstract
Methods to reliably assess the accuracy of genome sequence data are lacking. Currently completeness is only described qualitatively and mis-assemblies are overlooked. Here we present REAPR, a tool that precisely identifies errors in genome assemblies without the need for a reference sequence. We have validated REAPR on complete genomes or de novo assemblies from bacteria, malaria and Caenorhabditis elegans, and demonstrate that 86% and 82% of the human and mouse reference genomes are error-free, respectively. When applied to an ongoing genome project, REAPR provides corrected assembly statistics allowing the quantitative comparison of multiple assemblies. REAPR is available at http://www.sanger.ac.uk/resources/software/reapr/.
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Cites
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Self-citationScaffolding pre-assembled contigs using SSPACE.
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Cited by
BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs
Simão, F. A., Waterhouse, R. M., Ioannidis, P., Kriventseva, E. V., & Zdobnov, E. M. (2015) · Bioinformatics · doi:10.1093/bioinformatics/btv351 · Cited by 13,344
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Versatile genome assembly evaluation with QUAST-LG
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MLST revisited: the gene-by-gene approach to bacterial genomics
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Subsistence strategies in traditional societies distinguish gut microbiomes
Obregon-Tito, A. J., Tito, R. Y., Metcalf, J., Sankaranarayanan, K., Clemente, J. C., Ursell, L. K., Zech Xu, Z., Van Treuren, W., Knight, R., Gaffney, P. M., et al. (2015) · Nature Communications · doi:10.1038/ncomms7505 · Cited by 587
Metadata
- Authors
- Hunt, M., Kikuchi, T., Sanders, M., Newbold, C., Berriman, M., & Otto, T. D.
- Venue
- Genome Biology
- Published
- 2013-05-27
- Volume
- 14
- Issue
- 5
- Pages
- R47-R47
- ISSN
- 1465-6906 (ISSN-L)
- 1474-760X
- OpenAlex
- W2111829451
- Cited by
- 405
- References
- 31
- FWCI
- 16.14
- Type
- journal article
- Language
- en
- Open access
- gold
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