Cited by 418COVID-19 epidemiological studiesCOVID-19 Prevention and ImpactSARS-CoV-2 and COVID-19 Research

Effective public health measures to mitigate the spread of COVID-19: a systematic review

Open access
Ayouni, Imen, Maatoug, Jihen, Dhouib, Wafa, Zammit, Nawel, Fredj, Sihem Ben, Ghammam, Rim, Ghannem, Hassen·2021·BMC Public Health

Abstract

Background: In December 2019, a novel coronavirus (2019-nCoV) was recognized in Wuhan, China. It was characterised by rapid spread causing a pandemic. Multiple public health interventions have been implemented worldwide to decrease the transmission of the 2019 novel coronavirus disease (COVID-19). The objective of this systematic review is to evaluate the implemented public health interventions to control the spread of the outbreak of COVID-19. Methods: We systematically searched PubMed, Science Direct and MedRxiv for relevant articles published in English up to March 16, 2021. We included quasi experimental studies, clinical trials, cohort studies, longitudinal studies, case-control studies and interrupted time series. We included the studies that investigated the effect of the implemented public health measures to prevent and control the outbreak of 2019 novel coronavirus disease (COVID-19). Results: The database search using the predefined combinations of Mesh terms found 13,497 studies of which 3595 in PubMed, 7393 in Science Direct 2509 preprints in MedRxiv. After removal of the duplicates and the critical reading only 18 articles were included in this systematic review and processed for data extraction. Conclusions: Public health interventions and non-pharmaceutical measurements were effective in decreasing the transmission of COVID-19. The included studies showed that travel restrictions, borders measures, quarantine of travellers arriving from affected countries, city lockdown, restrictions of mass gathering, isolation and quarantine of confirmed cases and close contacts, social distancing measures, compulsory mask wearing, contact tracing and testing, school closures and personal protective equipment use among health workers were effective in mitigating the spread of COVID-19.

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  • Intensive contact tracing, isolation of infected people, and a range of public health and social measures can reduce the effective reproduction number below 1, causing the epidemic to decline.

    “With intensive contact tracing and the isolation of infected individuals, in addition to the implementation of a range of public health and social measures,21 the effective reproduction rate can be reduced to less than 1, and the epidemic will decline.”
  • Identifying cases and then tracing contacts and isolating or quarantining them can slow and reduce transmission.

    “Case identification followed by contact tracing and isolation or quarantine can slow and reduce transmission.16, 17, 18”

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Research works printed but not linked: 7

  1. [23]Salvatore M Basu D Ray D Kleinsasser M Purkayastha S Bhattacharyya R Comprehensive public health evaluation of lockdown as a non-pharmaceutical intervention on COVID-19 spread in India: national trends masking state-level variations BMJ Open 2020 10 12 e041778 10.1136/bmjopen-2020-041778 PMC7733201 33303462 · DOI
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  4. [31]Kepp KP Bjørnskov C Lockdown Effects on Sars-CoV-2 Transmission – The evidence from Northern Jutland. medRxiv. Cold Spring Harbor Laboratory Press 2021
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  6. [49]Grassly NC Pons-Salort M Parker EPK White PJ Ferguson NM Imperial College COVID-19 Response Team. Comparison of molecular testing strategies for COVID-19 control: a mathematical modelling study Lancet Infect Dis 2020 20 12 1381 1389 10.1016/S1473-3099(20)30630-7 32822577 PMC7434438 · DOI
  7. [53]Nguyen LH, Drew DA, Joshi AD, Guo C-G, Ma W, Mehta RS, et al. Risk of COVID-19 among frontline healthcare workers and the general community: a prospective cohort study. medRxiv [En ligne]. 25 mai 2020 [cité le 26 mars 2021]; Disponible: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273299/

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Authors
Ayouni, I., Maatoug, J., Dhouib, W., Zammit, N., Fredj, S. B., Ghammam, R., & Ghannem, H.
Affiliations
Hôpital Farhat Hached (TN)
Corresponding author
Ayouni, Imen
Venue
BMC Public Health
Published
2021-05-29
Volume
21
Issue
1
Pages
1015-1015
ISSN
1471-2458 (ISSN-L)
OpenAlex
W3165872846
Cited by
418
References
50
Citations by year
2026: 21 · 2025: 63 · 2024: 107 · 2023: 120 · 2022: 83 · 2021: 24
FWCI
8.35
Type
journal article
Language
en
Open access
Locations
  • BMC Public Health (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
  • Social Sciences › Sociology and Political Science › COVID-19 Prevention and Impact
  • Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
Keywords
COVID-19 pandemic, public health interventions, non-pharmaceutical interventions, travel restrictions, border measures, quarantine, lockdown, social distancing, masking, contact tracing, testing, school closures, personal protective equipment, healthcare workers
MeSH terms
COVID-19, SARS-CoV-2, China, Communicable Disease Control, Humans, Public Health

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