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Is a specialist breathlessness service more effective and cost-effective for patients with advanced cancer and their carers than standard care? Findings of a mixed-method randomised controlled trial
Open accessAbstract
BACKGROUND: Breathlessness is common in advanced cancer. The Breathlessness Intervention Service (BIS) is a multi-disciplinary complex intervention theoretically underpinned by a palliative care approach, utilising evidence-based non-pharmacological and pharmacological interventions to support patients with advanced disease. We sought to establish whether BIS was more effective, and cost-effective, for patients with advanced cancer and their carers than standard care. METHODS: A single-centre Phase III fast-track single-blind mixed-method randomised controlled trial (RCT) of BIS versus standard care was conducted. Participants were randomised to one of two groups (randomly permuted blocks). A total of 67 patients referred to BIS were randomised (intervention arm n = 35; control arm n = 32 received BIS after a two-week wait); 54 completed to the key outcome measurement. The primary outcome measure was a 0 to 10 numerical rating scale for patient distress due to breathlessness at two-weeks. Secondary outcomes were evaluated using the Chronic Respiratory Questionnaire, Hospital Anxiety and Depression Scale, Client Services Receipt Inventory, EQ-5D and topic-guided interviews. RESULTS: BIS reduced patient distress due to breathlessness (primary outcome: -1.29; 95% CI -2.57 to -0.005; P = 0.049) significantly more than the control group; 94% of respondents reported a positive impact (51/53). BIS reduced fear and worry, and increased confidence in managing breathlessness. Patients and carers consistently identified specific and repeatable aspects of the BIS model and interventions that helped. How interventions were delivered was important. BIS legitimised breathlessness and increased knowledge whilst making patients and carers feel 'not alone'. BIS had a 66% likelihood of better outcomes in terms of reduced distress due to breathlessness at lower health/social care costs than standard care (81% with informal care costs included). CONCLUSIONS: BIS appears to be more effective and cost-effective in advanced cancer than standard care. TRIAL REGISTRATION: RCT registration at ClinicalTrials.gov NCT00678405 (May 2008) and Current Controlled Trials ISRCTN04119516 (December 2008).
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“This empirical model was developed by the Cambridge Breathlessness Intervention Service (CBIS), a multidisciplinary home-based intervention of proven cost-effectiveness.”
From The Breathing, Thinking, Functioning clinical model: a proposal to facilitate evidence-based breathlessness management in chronic respiratory disease (2017) · cites this paper as [25]
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“Such services provide a brief, cost-effective intervention that impacts positively on distress from breathlessness, mastery, quality of life, and even survival.”
From The Breathing, Thinking, Functioning clinical model: a proposal to facilitate evidence-based breathlessness management in chronic respiratory disease (2017) · cites this paper as [25]
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Cites
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
(1990) · Cited by 24,217
EuroQol: a new facility for the measurement of health-related quality of life
(1990) · Health Policy · doi:10.1016/0168-8510(90)90421-9 · Cited by 15,736
Depression and quality of life in older persons: A review
Sivertsen, H., Bjørkløf, G. H., Engedal, K., Selbæk, G., & Helvik, A.-S. (2015) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000437299 · Cited by 14,152
Qualitative data analysis for applied policy research
(2002) · Analyzing Qualitative Data · doi:10.4324/9780203413081-14 · Cited by 4,964
Qualitative data analysis for applied policy research
Ritchie, J., & Spencer, L. (2010) · Analyzing qualitative data · doi:10.4324/9780203413081_chapter_9 · Cited by 4,800
Parshall, M. B., Schwartzstein, R. M., Adams, L., Banzett, R. B., Manning, H. L., Bourbeau, J., Calverley, P. M., Gift, A. G., Harver, A., Lareau, S. C., et al. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201111-2042st · Cited by 1,844
A measure of quality of life for clinical trials in chronic lung disease
Guyatt, G. H., Berman, L. B., Townsend, M., Pugsley, S. O., & Chambers, L. W. (1987) · Thorax · doi:10.1136/thx.42.10.773 · Cited by 1,721
Economic Evaluation in Clinical Trials
Glick, H. A., Doshi, J. A., Sonnad, S. S., & Polsky, D. E. (2014) · Oxford University Press eBooks · doi:10.1093/med/9780199685028.001.0001 · Cited by 910
Normative data for the HADS from a large non-clinical sample
Crawford, J. R., Henry, J. D., Crombie, C., & Taylor, E. P. (2001) · British Journal of Clinical Psychology · doi:10.1348/014466501163904 · Cited by 815 · cited 2×
“30 SD of the norm distribution [35] and depression was comparable (higher by 0.”
Background
Research works printed but not linked: 2
- Booth S, Moffat C, Burkin J: The Cambridge BIS Manual - Building a Breathlessness Intervention Service. 2012, Cambridge University Hospitals NHS Foundation Trust, Cambridge
- Curtis L: Unit Costs of Health and Social Care. 2012, PSSRU, Canterbury
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FERRELL, B. R., Temel, J. S., Temin, S., Alesi, E. R., Balboni, T. A., Basch, E., Firn, J. I., Paice, J. A., Peppercorn, J. M., Phillips, T., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2016.70.1474 · Cited by 2,148
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Kavalieratos, D., Corbelli, J. A., Zhang, D., Dionne-Odom, J. N., Ernecoff, N. C., Hanmer, J., Hoydich, Z., Ikejiani, D. Z., Klein‐Fedyshin, M., Zimmermann, C., et al. (2016) · JAMA · doi:10.1001/jama.2016.16840 · Cited by 1,183
Towards an expert consensus to delineate a clinical syndrome of chronic breathlessness
Johnson, M. J., Yorke, J., Hansen-Flaschen, J. H., Lansing, R., Ekström, M. P., Similowski, T., & Currow, D. C. (2017) · European Respiratory Journal · doi:10.1183/13993003.02277-2016 · Cited by 297
Spathis, A., Booth, S., Moffat, C., Hurst, R., Ryan, R., Chin, C., & Burkin, J. (2017) · npj Primary Care Respiratory Medicine · doi:10.1038/s41533-017-0024-z · Cited by 226
“This empirical model was developed by the Cambridge Breathlessness Intervention Service (CBIS), a multidisciplinary homebased intervention of proven cost-effectiveness.(25) Each of the three domains is supported by research evidence, as described above, and the model is theoretically underpinned by a ‘vicious flower’…”
MethodSelf-citationBajwah, S., Oluyase, A. O., Yi, D., Gao, W., Evans, C., Grande, G., Todd, C. J., Costantini, M., Murtagh, F. E., & Higginson, I. J. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012780.pub2 · Cited by 249
Self-citationWoolhouse, I., Bishop, L. J., Darlison, L., de Fonseka, D., Edey, A., Edwards, J. G., Finn, C. F., Fennell, D. A., Holmes, S., Kerr, K. M., et al. (2018) · Thorax · doi:10.1136/thoraxjnl-2017-211321 · Cited by 220
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Teo, I., Krishnan, A., & Lee, G. L. (2019) · Psycho-Oncology · doi:10.1002/pon.5103 · Cited by 205
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Hui, D., Bohlke, K., Bao, T., Campbell, T. C., Coyne, P. J., Currow, D. C., Gupta, A., Leiser, A., Mori, M., Nava, S., et al. (2021) · Journal of Clinical Oncology · doi:10.1200/jco.20.03465 · Cited by 198
Brighton, L. J., Miller, S., Farquhar, M. C., Booth, S., Yi, D., Gao, W., Bajwah, S., Man, W. D., Higginson, I. J., & Maddocks, M. M. (2018) · Thorax · doi:10.1136/thoraxjnl-2018-211589 · Cited by 153
Self-citationFarquhar, M. C., Prevost, A. T., McCrone, P., Brafman-Price, B., Bentley, A., Higginson, I. J., Todd, C. J., & Booth, S. (2016) · Trials · doi:10.1186/s13063-016-1304-6 · Cited by 148
Self-citationSullivan, D. R., Iyer, A. S., Enguidanos, S. M., Cox, C. E., Farquhar, M. C., Janssen, D. J. A., Lindell, K. O., Mularski, R. A., Smallwood, N., Turnbull, A. E., et al. (2022) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202207-1262st · Cited by 134
Self-citationManagement of breathlessness in patients with cancer: ESMO Clinical Practice Guidelines
Hui, D., Maddocks, M. M., Johnson, M. J., Ekström, M. P., Simon, S. T., Ogliari, A. C., Booth, S., & Ripamonti, C. I. (2020) · ESMO Open · doi:10.1136/esmoopen-2020-001038 · Cited by 125
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Luckett, T., Phillips, J. L., Johnson, M. J., Farquhar, M. C., Swan, F., Assen, T., Vandersman, P., & Booth, S. (2017) · European Respiratory Journal · doi:10.1183/13993003.00262-2017 · Cited by 99
Self-citationSmith, C. B., Phillips, T., & Smith, T. J. (2017) · American Society of Clinical Oncology Educational Book · doi:10.1200/edbk_175474 · Cited by 102
Yorke, J., Lloyd‐Williams, M., Smith, J. A., Blackhall, F. H., Harle, A. S. M., Warden, J., Ellis, J., Pilling, M. A., Haines, J., Luker, K. A., et al. (2015) · Supportive Care in Cancer · doi:10.1007/s00520-015-2810-x · Cited by 103
Johnson, M. J., Close, L., Gillon, S., Molassiotis, A., Lee, P. H., & Farquhar, M. C. (2016) · European Respiratory Journal · doi:10.1183/13993003.02089-2015 · Cited by 89
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Smallwood, N., Thompson, M. A., Warrender‐Sparkes, M., Eastman, P., Le, B. H. C., Irving, L. B., & Philip, J. A. M. (2018) · ERJ Open Research · doi:10.1183/23120541.00102-2017 · Cited by 81
Kako, J., Morita, T., Yamaguchi, T., Kobayashi, M., Sekimoto, A., Kinoshita, H., Ogawa, A., Zenda, S., Uchitomi, Y., Inoguchi, H., et al. (2018) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2018.07.001 · Cited by 78
Jadalla, A., Ginex, P., Coleman, M., Vrabel, M., & Bevans, M. (2020) · Clinical Journal of Oncology Nursing · doi:10.1188/20.cjon.31-50 · Cited by 77
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Booth, S., & Johnson, M. J. (2019) · Breathe · doi:10.1183/20734735.0200-2019 · Cited by 79
Self-citationJohnson, M. J., Kanaan, M., Richardson, G., Nabb, S., Torgerson, D., English, A., Barton, R., & Booth, S. (2015) · BMC Medicine · doi:10.1186/s12916-015-0453-x · Cited by 68
Self-citationNkhoma, K. B., Cook, A., Giusti, A., Farrant, L., Petrus, R., Petersen, I., Gwyther, L., Venkatapuram, S., & Harding, R. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-054386 · Cited by 68
Farquhar, M. C., Penfold, C., BENSON, J. A., Lovick, R., Mahadeva, R., Howson, S., Burkin, J., Booth, S., Gilligan, D., Todd, C. J., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0177081 · Cited by 68
Self-citationSwan, F., Newey, A., Bland, M., Allgar, V. L., Booth, S., Bausewein, C., Yorke, J., & Johnson, M. J. (2019) · Palliative Medicine · doi:10.1177/0269216319835393 · Cited by 64
Self-citationBreathlessness services as a new model of support for patients with respiratory disease
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Walshe, C., Dodd, S., Hill, M., Ockenden, N., Payne, S. A., Preston, N. J., & Algorta, G. P. (2016) · BMC Medicine · doi:10.1186/s12916-016-0746-8 · Cited by 57
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Chin, C. A., & Booth, S. (2016) · Postgraduate Medical Journal · doi:10.1136/postgradmedj-2015-133578 · Cited by 56
Self-citationThe TEAM Approach to Improving Oncology Outcomes by Incorporating Palliative Care in Practice
Bakitas, M. A., El-Jawahri, A. R., Farquhar, M. C., FERRELL, B. R., Grudzen, C. R., Higginson, I. J., Temel, J. S., Zimmermann, C., & Smith, T. J. (2017) · Journal of Oncology Practice · doi:10.1200/jop.2017.022939 · Cited by 53
Self-citationJohnson, M. J., Booth, S., Currow, D. C., Lam, L. T.-M., & Phillips, J. L. (2016) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2015.11.026 · Cited by 55
Self-citationCoombes, L., Braybrook, D. E., Roach, A., Scott, H. M., Harðardóttir, D., Bristowe, K., Ellis-Smith, C. I., Bluebond‐Langner, M., Fraser, L., Downing, J. D., et al. (2022) · European Journal of Pediatrics · doi:10.1007/s00431-022-04566-w · Cited by 52
Living with Metastatic Cancer: A Roadmap for Future Research
Tometich, D. B., Hyland, K. A., Soliman, H. H., Jim, H., & Oswald, L. B. (2020) · Cancers · doi:10.3390/cancers12123684 · Cited by 52
Simon, S. T., Weingärtner, V., Higginson, I. J., Benalia, H., Gysels, M., Murtagh, F. E., Spicer, J. F., Linde, P., Voltz, R., & Bausewein, C. (2016) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2016.02.016 · Cited by 46
Self-citationJohnson, M. J., Cockayne, S., Currow, D. C., Bell, K. J., Hicks, K., Fairhurst, C. M., Gabe, R., Torgerson, D. J., Jefferson, L., Oxberry, S. G., et al. (2019) · ESC Heart Failure · doi:10.1002/ehf2.12498 · Cited by 48
Man, W. D., Chowdhury, F., Taylor, R. S., Evans, R. A., Doherty, P., Singh, S. J., Booth, S., Thomason, D., Andrews, D., Lee, C., et al. (2016) · Chronic Respiratory Disease · doi:10.1177/1479972316642363 · Cited by 45
Self-citationJohnson, M. J., Bland, M., Gahbauer, E. A., Ekström, M. P., Sinnarajah, A., Gill, T. M., & Currow, D. C. (2016) · Journal of the American Geriatrics Society · doi:10.1111/jgs.13865 · Cited by 44
Systemic corticosteroids for the management of cancer-related breathlessness (dyspnoea) in adults
Haywood, A., Duc, J., Good, P. D., Khan, S. A., Rickett, K., Vayne-Bossert, P., & Hardy, J. R. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012704.pub2 · Cited by 43
Bone, A. E., Gao, W., Gomes, B., Sleeman, K. E., Maddocks, M. M., Wright, J. E., Yi, D., Higginson, I. J., Evans, C., & Elderly, O. (2016) · Journal of the American Geriatrics Society · doi:10.1111/jgs.14442 · Cited by 41
Self-citationModels of non-hospice palliative care: a review
Beasley, A. M., Bakitas, M. A., Edwards, R. L., & Kavalieratos, D. (2018) · Annals of Palliative Medicine · doi:10.21037/apm.2018.03.11 · Cited by 41
Assessment of Breathlessness in Lung Cancer: Psychometric Properties of the Dyspnea-12 Questionnaire
Tan, J.-Y. B., Yorke, J., Harle, A. S. M., Smith, J. A., Blackhall, F. H., Pilling, M. A., & Molassiotis, A. (2016) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2016.08.009 · Cited by 40
Nonpharmacological Interventions for Managing Breathlessness in Patients With Advanced Cancer
Gupta, A., Sedhom, R., Sharma, R., Zhang, A., Waldfogel, J. M., Feliciano, J. L., Day, J., Gersten, R. A., Davidson, P. M., Bass, E. B., et al. (2020) · JAMA Oncology · doi:10.1001/jamaoncol.2020.5184 · Cited by 39
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Morélot‐Panzini, C. (2017) · European Respiratory Journal · doi:10.1183/13993003.01383-2017 · Cited by 38
Booth, S., Galbraith, S., Ryan, R., Parker, R. A., & Johnson, M. J. (2015) · Palliative Medicine · doi:10.1177/0269216315607180 · Cited by 35
Self-citationThe Hand-Held Fan and the Calming Hand for People With Chronic Breathlessness: A Feasibility Trial
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Yu, S., Sun, K., Xing, X., Zhong, Y., Yan, X., Qiu, W., & Yan, M. (2019) · Journal of Palliative Medicine · doi:10.1089/jpm.2019.0140 · Cited by 35
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Immediate Effect of Fan Therapy in Terminal Cancer With Dyspnea at Rest: A Meta-Analysis
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Self-citationReilly, C. C., Bausewein, C., Pannell, C., Moxham, J., Jolley, C. J., & Higginson, I. J. (2015) · Palliative Medicine · doi:10.1177/0269216315600103 · Cited by 31
Self-citationWalshe, C., Algorta, G. P., Dodd, S., Hill, M., Ockenden, N., Payne, S. A., & Preston, N. J. (2016) · BMC Palliative Care · doi:10.1186/s12904-016-0134-3 · Cited by 31
Oriani, A., Dunleavy, L., Sharples, P., Algorta, G. P., & Preston, N. J. (2020) · BMC Palliative Care · doi:10.1186/s12904-019-0506-6 · Cited by 32
Schunk, M. V., Le, L. D., Syunyaeva, Z., Haberland, B., Tänzler, S., Mansmann, U., Schwarzkopf, L., Seidl, H., Streitwieser, S., Hofmann, M., et al. (2021) · European Respiratory Journal · doi:10.1183/13993003.02139-2020 · Cited by 30
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Kako, J., Morita, T., Yamaguchi, T., Sekimoto, A., Kobayashi, M., Kinoshita, H., Ogawa, A., Zenda, S., Uchitomi, Y., Inoguchi, H., et al. (2017) · American Journal of Hospice and Palliative Medicine® · doi:10.1177/1049909117707905 · Cited by 27
Yorke, J., Johnson, M. J., Punnett, G., Smith, J. A., Blackhall, F. H., Lloyd‐Williams, M., Mackereth, P., Haines, J., Ryder, W. D. J., Krishan, A., et al. (2022) · BMJ Supportive & Palliative Care · doi:10.1136/spcare-2022-003924 · Cited by 26
McVeigh, C., Reid, J., Larkin, P. J., Porter, S., & Hudson, P. (2017) · BMC Palliative Care · doi:10.1186/s12904-017-0220-1 · Cited by 26
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Bayly, J., Edwards, B., Peat, N., Warwick, G., Hennig, I. M., Arora, A., Wilcock, A., Higginson, I. J., & Maddocks, M. M. (2018) · Pilot and Feasibility Studies · doi:10.1186/s40814-018-0350-0 · Cited by 23
Self-citationA mixed-methods pilot study of handheld fan for breathlessness in interstitial lung disease
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Maddocks, M. M., Brighton, L. J., Farquhar, M. C., Booth, S., Miller, S., Klass, L., Tunnard, I., Yi, D., Gao, W., Bajwah, S., et al. (2019) · Health Services and Delivery Research · doi:10.3310/hsdr07220 · Cited by 22
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Self-citationJohnston, K., Young, M., Kay, D., Booth, S., Spathis, A., & Williams, M. (2020) · BMC Medical Education · doi:10.1186/s12909-020-02006-7 · Cited by 19
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Bayly, J., Ahmedzai, H. H., Blandini, M. G., Bressi, B., Caraceni, A. T., Vasconcelos, J. C., Costi, S., Fugazzaro, S., Guberti, M., Guldin, M., et al. (2023) · Palliative Care and Social Practice · doi:10.1177/26323524231179979 · Cited by 18
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Luckett, T., Roberts, M. M., Smith, T., Garcia, M., Dunn, S., Swan, F., Ferguson, C., Kochovska, S., Phillips, J. L., Pearson, M., et al. (2022) · BMC Pulmonary Medicine · doi:10.1186/s12890-022-01925-z · Cited by 16
Isenberg, S. R., Aslakson, R. A., & Smith, T. J. (2017) · Epidemiologic Reviews · doi:10.1093/epirev/mxw002 · Cited by 16
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Westley, T., Syrowatka, A., Henault, D., Rho, Y. S., Khazoom, F., Chang, S.-L., Tamblyn, R. M., Mayo, N. E., & Meguerditchian, A. N. (2017) · Journal of Geriatric Oncology · doi:10.1016/j.jgo.2017.10.003 · Cited by 15
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Farquhar, M. C. (2016) · European Respiratory Society eBooks · doi:10.1183/2312508x.10011315 · Cited by 13
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Metadata
- Authors
- Farquhar, M. C., Prevost, A. T., McCrone, P., Brafman-Price, B., Bentley, A., Higginson, I. J., Todd, C., & Booth, S.
- Affiliations
- University of Cambridge (GB)
- King's College London (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- University of Manchester (GB)
- Corresponding author
- Farquhar, Morag C
- ORCID
- Venue
- BMC Medicine
- Published
- 2014-10-31
- Volume
- 12
- Issue
- 1
- Pages
- 194-194
- ISSN
- 1741-7015 (ISSN-L)
- PMC
- PMC4222435
- OpenAlex
- W2070706399
- Cited by
- 201
- References
- 38
- Citations by year
- 2026: 5 · 2025: 8 · 2024: 12 · 2023: 5 · 2022: 21 · 2021: 16 · 2020: 22 · 2019: 24 · 2018: 19 · 2017: 21 · 2016: 32 · 2015: 14 · 2014: 1
- FWCI
- 22.56
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- BMC Medicine (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- UEA Digital Repository (University of East Anglia) (acceptedVersion)
- Apollo (University of Cambridge) (submittedVersion, cc-by)
- Research Portal (King's College London) (submittedVersion, cc-by)
- Research Explorer (The University of Manchester) (submittedVersion)
- Spiral (Imperial College London) (submittedVersion, cc-by)
- Funders
- Macmillan Cancer Support
- National Institute for Health and Care Research (PB-PG-0107-11134, NF-SI-0611-10209)
- University of Cambridge
- King's College London
- Cambridge University Hospitals
- Research for Patient Benefit Programme
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- dyspnea, advanced cancer, palliative care, caregivers, cost-effectiveness, non-pharmacological treatment, anxiety and depression, informal care costs
- MeSH terms
- Adult, Aged, Aged, 80 and over, Anxiety, Cost-Benefit Analysis, Dyspnea, Female, Humans, Male, Middle Aged, Neoplasms, Occupational Therapy, Palliative Care, Surveys and Questionnaires, Single-Blind Method, Caregivers, Health Care Costs, Outcome Assessment, Health Care, Physical Therapy Modalities
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