The DOI matches its Crossref record; 125 of the 125 references it cites were found in a registry or an index.
Advancement and applications of peptide phage display technology in biomedical science
Open accessAbstract
Combinatorial phage library is a powerful research tool for high-throughput screening of protein interactions. Of all available molecular display techniques, phage display has proven to be the most popular approach. Screening phage-displayed random peptide libraries is an effective means of identifying peptides that can bind target molecules and regulate their function. Phage-displayed peptide libraries can be used for (i) B-cell and T-cell epitope mapping, (ii) selection of bioactive peptides bound to receptors or proteins, disease-specific antigen mimics, peptides bound to non-protein targets, cell-specific peptides, or organ-specific peptides, and (iii) development of peptide-mediated drug delivery systems and other applications. Targeting peptides identified using phage display technology may be useful for basic research and translational medicine. In this review article, we summarize the latest technological advancements in the application of phage-displayed peptide libraries to applied biomedical sciences.
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Metadata
- Authors
- Wu, C.-H., Liu, I.-J., Lu, R.-M., & Wu, H.-C.
- Venue
- Journal of Biomedical Science
- Published
- 2016-01-19
- Volume
- 23
- Issue
- 1
- Pages
- 8-8
- ISSN
- 1021-7770 (ISSN-L)
- 1423-0127
- OpenAlex
- W2254535559
- Cited by
- 339
- References
- 125
- FWCI
- 14.45
- Type
- journal article
- Language
- en
- Open access
- diamond
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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