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Cited by 401

The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.

Effects of exosomes on pre-metastatic niche formation in tumors

Open access
Guo, Yaxin, Ji, Xiang, Liu, Jinbo, Fan, Dandan, Zhou, Quanbo, Chen, Chen, Wang, Weiwei, Wang, Guixian, Wang, Haijiang, Yuan, Weitang, Ji, Zhenyu, Sun, Zhenqiang·2019·Molecular Cancer

Abstract

A pre-metastatic niche is a microenvironment prepared for the colonization of circulating tumor cells in specific organs. Exosomes are extracellular vesicles with a variety of biological functions. Exosomes play an irreplaceable role in the development of pre-metastatic niches, and mainly function as communication medium. In this review, we analyzed the effects of exosomes on pre-metastatic niches from various perspectives, including inflammation, immune response, angiogenesis, organotropism, matrix remodeling and biomarker expression. In particular, exosomes express programmed death ligand 1 (PD-L1) and cause the immune escape of tumor cells. The immunomodulatory effects of exosomes and their potential in liquid diagnosis have drawn our attention. The potential value of exosomes and pre-metastatic niches will be realized in the field of immunity therapy.

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Crossref · 10.1186/s12943-019-0995-1

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Metadata

Authors
Guo, Y., Ji, X., Liu, J., Fan, D., Zhou, Q., Chen, C., Wang, W., Wang, G., Wang, H., Yuan, W., Ji, Z., & Sun, Z.
Venue
Molecular Cancer
Published
2019-03-11
Volume
18
Issue
1
Pages
39-39
ISSN
1476-4598 (ISSN-L)
OpenAlex
W2933960973
Cited by
401
References
105
FWCI
15.76
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Effects of exosomes on pre-metastatic niche formation in tumors. https://app.cochat.ai/papers/10.1186/s12943-019-0995-1
The paper
Guo, Y., Ji, X., Liu, J., Fan, D., Zhou, Q., Chen, C., Wang, W., Wang, G., Wang, H., Yuan, W., Ji, Z., & Sun, Z. (2019). Effects of exosomes on pre-metastatic niche formation in tumors. Molecular Cancer. https://doi.org/10.1186/s12943-019-0995-1

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.