Comparative analyses of DHA-Phosphatidylcholine and recombination of DHA-Triglyceride with Egg-Phosphatidylcholine or Glycerylphosphorylcholine on DHA repletion in n-3 deficient mice

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

Folch, J., Lees, M., & Stanley, G. H. S. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64849-5 · Cited by 65,189 · see citing works

Lipids and Lipid-Based Formulations: Optimizing the Oral Delivery of Lipophilic Drugs

Porter, C. J. H., Trevaskis, N. L., & Charman, W. N. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2197 · Cited by 1,824 · see citing works

Adolescent cortical development: A critical period of vulnerability for addiction

Crews, F., He, J., & Hodge, C. (2007) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.12.001 · Cited by 1,091 · see citing works

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

Nguyen, L. N., Ma, D., Shui, G., Wong, P., Cazenave-Gassiot, A., Zhang, X., Wenk, M. R., Goh, E. L. K., & Silver, D. L. (2014) · Nature · doi:10.1038/nature13241 · Cited by 1,048 · see citing works

Polyunsaturated Fatty Acids in Male and Female Reproduction1

Wathes, D. C., Abayasekara, D. R. E., & Aitken, R. J. (2007) · Biology of Reproduction · doi:10.1095/biolreprod.107.060558 · Cited by 794 · see citing works

Epigenetic transgenerational actions of environmental factors in disease etiology

Skinner, M. K., Manikkam, M., & Guerrero‐Bosagna, C. (2010) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2009.12.007 · Cited by 713 · see citing works

Is docosahexaenoic acid, an n−3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals

McCann, J. C., & Ames, B. N. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn.82.2.281 · Cited by 498 · see citing works

Is docosahexaenoic acid, an n−3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals

McCann, J. C., & Ames, B. N. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.2.281 · Cited by 412 · see citing works

Strategies for transporting nanoparticles across the blood–brain barrier

Zhang, T.-T., Li, W., Meng, G., Wang, P., & Liao, W. (2016) · Biomaterials Science · doi:10.1039/c5bm00383k · Cited by 308 · see citing works

Omega-3 polyunsaturated fatty acids critically regulate behaviour and gut microbiota development in adolescence and adulthood

Robertson, R. C., Seira Oriach, C., Murphy, K., Moloney, G. M., Cryan, J. F., Dinan, T. G., Paul Ross, R., & Stanton, C. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.07.145 · Cited by 268 · see citing works

Improved spatial learning performance of fat-1 mice is associated with enhanced neurogenesis and neuritogenesis by docosahexaenoic acid

He, C., Qu, X., Cui, L., Wang, J., & Kang, J. X. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904835106 · Cited by 233 · see citing works

Lipid Remodeling of Murine Epididymosomes and Spermatozoa During Epididymal Maturation1

Pons‐Rejraji, H., Sion, B., Prensier, G., Carreras, M., Motta, C., Frenoux, J., Véricel, E., Grizard, G., Vernet, P., & Drevet, J. R. (2006) · Biology of Reproduction · doi:10.1095/biolreprod.105.049304 · Cited by 206 · see citing works

Half‐lives of docosahexaenoic acid in rat brain phospholipids are prolonged by 15 weeks of nutritional deprivation of n‐3 polyunsaturated fatty acids

DeMar, J. C., Ma, K., Bell, J. M., & Rapoport, S. I. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02789.x · Cited by 194 · see citing works

Reversal of docosahexaenoic acid deficiency in the rat brain, retina, liver, and serum

Moriguchi, T., Loewke, J., Garrison, M. E., Catalan, J. N., & Salem, N. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31666-7 · Cited by 185 · see citing works

Enhanced increase of omega-3 index in healthy individuals with response to 4-week n-3 fatty acid supplementation from krill oil versus fish oil

Ramprasath, V. R., Eyal, I., Zchut, S., & Jones, P. J. (2013) · Lipids in Health and Disease · doi:10.1186/1476-511x-12-178 · Cited by 175 · see citing works

Directly Quantitated Dietary (n-3) Fatty Acid Intakes of Pregnant Canadian Women Are Lower than Current Dietary Recommendations

Denomme, J., Stark, K. D., & Holub, B. J. (2005) · Journal of Nutrition · doi:10.1093/jn/135.2.206 · Cited by 174 · see citing works

Docosahexaenoic acid supplementation fully restores fertility and spermatogenesis in male delta-6 desaturase-null mice

Roqueta‐Rivera, M., Stroud, C. K., Haschek, W. M., Akare, S., Segre, M., Brush, R. S., Agbaga, M., Anderson, R. E., Hess, R. A., & Nakamura, M. (2009) · Journal of Lipid Research · doi:10.1194/jlr.m001180 · Cited by 154 · see citing works

Spermatozoa and seminal plasma fatty acids as predictors of cryopreservation success

Martínez-Soto, J. C., Landeras, J., & Gadea, J. (2012) · Andrology · doi:10.1111/j.2047-2927.2012.00040.x · Cited by 131 · see citing works

Infant vision and retinal function in studies of dietary long-chain polyunsaturated fatty acids: methods, results, and implications

Neuringer, M. D. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.1.256s · Cited by 127 · see citing works

Higher efficacy of dietary DHA provided as a phospholipid than as a triglyceride for brain DHA accretion in neonatal piglets

Liu, L., Bartke, N., Van Daele, H., Lawrence, P., Qin, X., Park, H. G., Kothapalli, K., Windust, A., Bindels, J., Wang, Z., et al. (2014) · Journal of Lipid Research · doi:10.1194/jlr.m045930 · Cited by 117 · see citing works

Effect of dietary docosahexaenoic acid (DHA) in phospholipids or triglycerides on brain DHA uptake and accretion

Kitson, A. P., Metherel, A. H., Chen, C. T., Domenichiello, A. F., Trépanier, M., Berger, A., & Bazinet, R. P. (2016) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2016.02.009 · Cited by 107 · see citing works

Human plasma albumin transports [13C]docosahexaenoic acid in two lipid forms to blood cells

BROSSARD, N., Croset, M., Normand, S., Pousin, J., Lecerf, J. M., Laville, M., Tayot, J. L., & Lagarde, M. (1997) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37175-3 · Cited by 98 · see citing works

Biomarkers of DHA status

Kuratko, C. N., & Salem, N. (2009) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2009.05.007 · Cited by 88 · see citing works

The Assessment of Cognitive Performance in Children: Considerations for Detecting Nutritional Influences

Hughes, D., & Bryan, J. (2003) · Nutrition Reviews · doi:10.1301/nr.2003.dec.413-422 · Cited by 78 · see citing works

DHA-PC and DHA-PS improved Aβ1–40 induced cognitive deficiency uncoupled with an increase in brain DHA in rats

Wen, M., Ding, L., Zhang, L., Zhou, M., Xu, J., Wang, J., Wang, Y., & Xue, C. (2016) · Journal of Functional Foods · doi:10.1016/j.jff.2016.02.004 · Cited by 71 · see citing works

Delta-6 desaturation of alpha-linolenic acid in brain and liver during development and aging in the mouse

Bourre, J. M., & Piciotti, M. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90335-5 · Cited by 66 · see citing works

Age dependent incorporation of 14C-DHA into rat brain and body tissues after dosing various 14C-DHA-esters

Graf, B. A., Duchateau, G. S. M. J. E., Patterson, A. B., Mitchell, E. S., van Bruggen, P., Koek, J. H., Melville, S., & Verkade, H. J. (2010) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2010.05.004 · Cited by 61 · see citing works

n-3 Deficient and docosahexaenoic acid-enriched diets during critical periods of the developing prenatal rat brain

Schiefermeier, M., & Yavin, E. (2002) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)30195-4 · Cited by 60 · see citing works

Competitive effect of alpha- and gamma-lionlenyl-CoA in linoleyl-CoA desaturation to gamma-linolenyl-CoA.

Brenner, R. R., Peluffo, R. O., Nervi, A. M., & Thomas, M. E. D. (1969) · PubMed · Cited by 43 · see citing works

Short-term Effects of Different Fish Oil Formulations on Tissue Absorption of Docosahexaenoic Acid in Mice Fed High- and Low-Fat Diets

Ding, N., Xue, Y., Tang, X., Sun, Z., Yanagita, T., Xue, C., & Wang, Y. (2013) · Journal of Oleo Science · doi:10.5650/jos.62.883 · Cited by 41 · see citing works

Competitive effect of α- and γ-linolenyl-CoA and arachidonyl-CoA in linoleyl-CoA desaturation to γ-linolenyl-CoA

Brenner, R. R., Peluffo, R. O., Nervi, A. M., & Tomás, M. E. D. (1969) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(69)90202-1 · Cited by 41 · see citing works

Absorption of Phospholipides

Bloom, B., Kiyasu, J. Y., Reinhardt, W. O., & Chaikoff, L. L. (1954) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1954.177.1.84 · Cited by 38 · see citing works

Metabolic fate of an oral tracer dose of [13C]docosahexaenoic acid triglycerides in the rat

BROSSARD, N., Croset, M., Lecerf, J. M., Pachiaudi, C., Normand, S., Chirouze, V., Macovschi, O., Riou, J. P., Tayot, J. L., & Lagarde, M. (1996) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1996.270.4.r846 · Cited by 33 · see citing works

Diet (n-3) Polyunsaturated Fatty Acid Content and Parity Affect Liver and Erythrocyte Phospholipid Fatty Acid Composition in Female Rats3

Levant, B., Ozias, M. K., & Carlson, S. E. (2007) · Journal of Nutrition · doi:10.1093/jn/137.11.2425 · Cited by 31 · see citing works

Plasticity of Mouse Brain Docosahexaenoic Acid: Modulation by Diet and Age

Moriguchi, T., Harauma, A., & Salem, N. (2013) · Lipids · doi:10.1007/s11745-013-3775-5 · Cited by 27 · see citing works

Dietary (n-3) Fatty Acids Alter Fatty Acid Composition and Prostaglandin Synthesis in Rat Testis

Chanmugam, P., Boudreau, M. D., & Hwang, D. H. (1991) · Journal of Nutrition · doi:10.1093/jn/121.8.1173 · Cited by 25 · see citing works

Retailoring docosahexaenoic acid‐containing phospholipid species during impaired neurogenesis following omega‐3 α‐linolenic acid deprivation

Brand, A., Crawford, M. A., & Yavin, E. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06866.x · Cited by 22 · see citing works

Repletion of n‐3 Fatty Acid Deficient Dams with α‐Linolenic Acid: Effects on Fetal Brain and Liver Fatty Acid Composition

Harauma, A., Salem, N., & Moriguchi, T. (2010) · Lipids · doi:10.1007/s11745-010-3443-y · Cited by 22 · see citing works

Lysophosphatidylserine form DHA maybe the most effective as substrate for brain DHA accretion

Tsushima, T., Ohkubo, T., Onoyama, K., Linder, M., & Takahashi, K. (2013) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2013.11.013 · Cited by 20 · see citing works

Health benefits of dietary marine DHA/EPA-enriched glycerophospholipids

Zhang, T.-T., Xu, J., Wang, Y.-M., & Xue, C.-H. (2019) · Progress in Lipid Research · doi:10.1016/j.plipres.2019.100997 · Cited by 339 · see citing works

Ultrasound-assisted one-phase solvent extraction coupled with liquid chromatography-quadrupole time-of-flight mass spectrometry for efficient profiling of egg yolk lipids

Xie, Y., Wu, B., Wu, Z., Tu, X., Xu, S., Lv, X., Yin, H., Xiang, J., Chen, H., & Wei, F. (2020) · Food Chemistry · doi:10.1016/j.foodchem.2020.126547 · Cited by 66 · see citing works

Structured form of DHA prevents neurodegenerative disorders: A better insight into the pathophysiology and the mechanism of DHA transport to the brain.

Balakrishnan, J., Kannan, S., & Govindasamy, A. (2020) · Nutrition Research · doi:10.1016/j.nutres.2020.12.003 · Cited by 43 · see citing works

Solid Matrix-Supported Supercritical CO2 Enhances Extraction of γ-Linolenic Acid from the Cyanobacterium Arthrospira (Spirulina) platensis and Bioactivity Evaluation of the Molecule in Zebrafish

Yang, X., Li, Y., Li, Y., Ye, D., Yuan, L., Sun, Y., Han, D., & Hu, Q. (2019) · Marine Drugs · doi:10.3390/md17040203 · Cited by 45 · see citing works

A comparative study about EPA-PL and EPA-EE on ameliorating behavioral deficits in MPTP-induced mice with Parkinson’s disease by suppressing oxidative stress and apoptosis

Wang, C., Wang, D., Zhang, T., Yanagita, T., Xue, C., Chang, Y., & Wang, Y. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.09.027 · Cited by 42 · see citing works

Phospholipid and Lipid Derivatives as Potential Neuroprotective Compounds

Tayebati, S. K. (2018) · Molecules · doi:10.3390/molecules23092257 · Cited by 31 · see citing works

Comparative Analyses of EPA-Phosphatidylcholine, EPA-Lysophosphatidylcholine, and DHA-Lysophosphatidylcholine on DHA and EPA Repletion in n-3 PUFA-Deficient Mice

Cui, X.-Y., Jiang, S., Wang, C., Yang, J., Zhao, Y., Xue, C., Wang, Y.-M., & Zhang, T. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c06462 · Cited by 20 · see citing works

Intestinal bioavailability of n-3 long-chain polyunsaturated fatty acids influenced by the supramolecular form of phospholipids

Sehl, A., Couëdelo, L., Vaysse, C., & Cansell, M. (2020) · Food & Function · doi:10.1039/c9fo02953b · Cited by 13 · see citing works

Short-term supplementation of EPA-enriched ethanolamine plasmalogen increases the level of DHA in the brain and liver of n-3 PUFA deficient mice in early life after weaning

Fu, S.-S., Wen, M., Zhao, Y., Shi, H.-H., Wang, Y., Xue, C.-H., Wei, Z., & Zhang, T. (2021) · Food & Function · doi:10.1039/d1fo03345j · Cited by 13 · see citing works

Development of omega-3 enriched egg using fish-oil based fowl feed supplement

Antony, B., Benny, M., Jose, S., Jacob, S., Nedumpilly, V., Ajimol, M. S., & Abraham, G. (2024) · The Journal of Applied Poultry Research · doi:10.1016/j.japr.2024.100429 · Cited by 11 · see citing works

N‐3 PUFA‐Deficiency in Early Life Exhibits Aggravated MPTP‐Induced Neurotoxicity in Old Age while Supplementation with DHA/EPA‐Enriched Phospholipids Exerts a Neuroprotective Effect

Wu, F., Wang, D., Shi, H., Wang, C., Xue, C., Wang, Y., & Zhang, T. (2021) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202100339 · Cited by 10 · see citing works

Comprehensive lipid profile analysis of three fish roe by untargeted lipidomics using ultraperformance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry

Wang, J., Yu, X., Ran, S., & Wei, F. (2024) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2024.106782 · Cited by 9 · see citing works

Fish roe phospholipids and health: composition, extraction, storage and brain health application

Ahmmed, M. K., Ahmmed, F., Carne, A., Tian, H. S., & Bekhit, A. E. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-819893-3.00005-9 · Cited by 9 · see citing works

Preparation of n‐3 Polyunsaturated Phosphatidylglycerol from Salmon Roe Lipids by Phospholipase D and In Vitro Digestion

Chen, L., Beppu, F., Miyashita, K., & Hosokawa, M. (2019) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201900201 · Cited by 8 · see citing works

The rapid effects of eicosapentaenoic acid (EPA) enriched phospholipids on alleviating exercise fatigue in mice

Wang, C., Shi, H.-H., Zhang, L., Ding, L., Xue, C., Yanagita, T., Zhang, T., & Wang, Y. (2019) · RSC Advances · doi:10.1039/c9ra05181c · Cited by 8 · see citing works

Providing lysophosphatidylcholine-bound omega-3 fatty acids increased eicosapentaenoic acid, but not docosahexaenoic acid, in the cortex of mice with the apolipoprotein E3 or E4 allele

Andriambelo, B., Vachon, A., Dansereau, M., Laurent, B., & Plourde, M. (2024) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2024.102661 · Cited by 6 · see citing works

Sustainable and biotechnological production of docosahexaenoic acid from marine protists and slaughterhouse waste

Hachem, M., Ali, A. H., Hejou, M., Almansoori, A. S., Abulhassan, S., Hussein, F., Khalifa, R., Khalifa, R., & Corridon, P. R. (2025) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2025.2499895 · Cited by 1 · see citing works

Impact de la forme moléculaire et supramoléculaire de vectorisation des acides gras polyinsaturés n-3 sur leur biodisponibilité : étude physico-chimique et in vivo chez le rat

Sehl, A. (2019) · doi:10.70675/62c7c58dz3c2az404dzbf92z4a7b238ee0ab · Cited by 1 · see citing works

Recent advances in phospholipid-DHA: bioactivity for brain health and product development

Guo, X., Yu, X., Hu, X., Guo, H., & 任路静 (2026) · Food Science and Human Wellness · doi:10.26599/fshw.2025.9250475

Arachidonic Acid Enhances Reproductive Performance and Oocyte Quality of Female Blotched Snakehead (Channa maculata) via Activation of the TGF-β/Smad Signaling Pathway

Fei, S., He, J., Yang, T., Zhang, J., Ou, M., Liu, H., Zhang, X., Luo, Q., & Zhao, J. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27198540

Replenishment of Docosahexaenoic Acid (DHA) in Dietary n‐3‐Deficient Mice Fed DHA in Triglycerides or Phosphatidylcholines After Weaning

Wang, D., Wu, F., Wen, M., Ding, L., Du, L., Xue, C., Xu, J., & Wang, Y. (2018) · Journal of Food Science · doi:10.1111/1750-3841.14017 · Cited by 19 · see citing works

Comparative Analyses of EPA-Phosphatidylcholine, EPA-Lysophosphatidylcholine, and DHA-Lysophosphatidylcholine on DHA and EPA Repletion in n-3 PUFA-Deficient Mice

Cui, X.-Y., Jiang, S., Wang, C., Yang, J., Zhao, Y., Xue, C., Wang, Y.-M., & Zhang, T. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c06462 · Cited by 20 · see citing works

Effects of short‐term supplementation with DHA ‐enriched phosphatidylcholine and phosphatidylserine on lipid profiles in the brain and liver of n‐3 PUFA ‐deficient mice in early life after weaning

Zuo, W., Wen, M., Zhao, Y., Li, X., Xue, C., Yanagita, T., Wang, Y., & Zhang, T. (2024) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.13625 · Cited by 10 · see citing works

Repletion of n‐3 Fatty Acid Deficient Dams with α‐Linolenic Acid: Effects on Fetal Brain and Liver Fatty Acid Composition

Harauma, A., Salem, N., & Moriguchi, T. (2010) · Lipids · doi:10.1007/s11745-010-3443-y · Cited by 22 · see citing works

Brain docosahexaenoic acid accretion is greater when supplied as phosphatidylcholine than as triacylglycerol in piglets (821.11)

Liu, L., Bartke, N., Daele, H. V., Lawrence, P., Qin, X., Park, H., Kothapalli, K. S. D., Windust, A. J., Wang, Z., & Brenna, J. T. (2014) · The FASEB Journal · doi:10.1096/fasebj.28.1_supplement.821.11