The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Recent advances of fluorescent biosensors based on cyclic signal amplification technology in biomedical detection
Open accessAbstract
The cyclic signal amplification technology has been widely applied for the ultrasensitive detection of many important biomolecules, such as nucleic acids, proteins, enzymes, adenosine triphosphate (ATP), metal ions, exosome, etc. Due to their low content in the complex biological samples, traditional detection methods are insufficient to satisfy the requirements for monitoring those biomolecules. Therefore, effective and sensitive biosensors based on cyclic signal amplification technology are of great significance for the quick and simple diagnosis and treatment of diseases. Fluorescent biosensor based on cyclic signal amplification technology has become a research hotspot due to its simple operation, low cost, short time, high sensitivity and high specificity. This paper introduces several cyclic amplification methods, such as rolling circle amplification (RCA), strand displacement reactions (SDR) and enzyme-assisted amplification (EAA), and summarizes the research progress of using this technology in the detection of different biomolecules in recent years, in order to provide help for the research of more efficient and sensitive detection methods. Graphical Abstract
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Citations
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Cited by
Recent advances in isolation and detection of exosomal microRNAs related to Alzheimer's disease
Pishbin, E., Sadri, F., Dehghan, A., Kiani, M. J., Hashemi, N., Zare, I., Mousavi, P., & Rahi, A. (2023) · Environmental Research · doi:10.1016/j.envres.2023.115705 · Cited by 25
Metadata
- Authors
- Qu, H., Fan, C., Chen, M., Zhang, X., Yan, Q., Wang, Y., Zhang, S., Gong, Z., Shi, L., Li, X., Liao, Q., Xiang, B., Zhou, M., Guo, C., Li, G., Zeng, Z., Wu, X., & Xiong, W.
- Venue
- Journal of Nanobiotechnology
- Published
- 2021-12
- Volume
- 19
- Issue
- 1
- Pages
- 403-403
- ISSN
- 1477-3155 (ISSN-L)
- OpenAlex
- W4200260085
- Cited by
- 306
- References
- 9
- FWCI
- 19.12
- Type
- journal article
- Language
- en
- Open access
- gold
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- Qu, H., Fan, C., Chen, M., Zhang, X., Yan, Q., Wang, Y., Zhang, S., Gong, Z., Shi, L., Li, X., Liao, Q., Xiang, B., Zhou, M., Guo, C., Li, G., Zeng, Z., Wu, X., & Xiong, W. (2021). Recent advances of fluorescent biosensors based on cyclic signal amplification technology in biomedical detection. Journal of Nanobiotechnology. https://doi.org/10.1186/s12951-021-01149-z
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