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Unmethylated‐maspin DNA in maternal plasma is associated with severe preeclampsia

Qi, Y., Teng, F., Zhou, Q., Liu, Y., Wu, J., Yu, S., Zhang, X., Ma, M., Zhou, N., & Chen, L. (2015) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.12691 · Cited by 17 · see citing works

Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus

Suzuki, M., Maekawa, R., Patterson, N. E., Reynolds, D. M., Calder, B. R., Reznik, S. E., Heo, H. J., Einstein, F. H., & Greally, J. M. (2016) · Clinical Epigenetics · doi:10.1186/s13148-016-0234-1 · Cited by 16 · see citing works

Promoter hypomethylation and increased maspin expression in preeclamptic placentas in a Chinese population

Liu, Q., Qiao, F. Y., Shi, X., Liu, H. Y., Gong, X., & Wu, Y. (2014) · Placenta · doi:10.1016/j.placenta.2014.08.088 · Cited by 16 · see citing works

Naturally Occurring Variation in Trophoblast Invasion as a Source of Novel (Epigenetic) Biomarkers

van Dijk, M., Visser, A., Posthuma, J., Poutsma, A., & Oudejans, C. B. M. (2012) · Frontiers in Genetics · doi:10.3389/fgene.2012.00022 · Cited by 16 · see citing works

Methylation Mediated Silencing of miR-155 Suppresses the Development of Preeclampsia In Vitro and In Vivo by Targeting FOXO3

Luo, X., Pan, C., Guo, X., Gu, C., Huang, Y., Guo, J. H., Zeng, Y., Yue, J., & Cui, S. (2022) · Mediators of Inflammation · doi:10.1155/2022/4250621 · Cited by 16 · see citing works

Preeclampsia is Associated with Decreased Methylation of theGNA12Promoter

Ye, W., Shen, L. H., Xiong, Y., Zhou, Y., Gu, H., & Yang, Z. (2015) · Annals of Human Genetics · doi:10.1111/ahg.12136 · Cited by 15 · see citing works

Effects of Tissue Factor Pathway Inhibitor-2 Expression on Biological Behavior of BeWo and JEG-3 Cell Lines

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Analysis of gene expression and preliminary study of methylation about 11β‐ HSD2 gene in placentas of C hinese pre‐eclampsia patients of Han ethnicity

Hu, W., Wang, H., & Huang, H. (2014) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.12555 · Cited by 15 · see citing works

Promoter Methylation Status of WNT2 in Placenta from Patients with Preeclampsia

Liu, Y., & Ma, Y. (2017) · Medical Science Monitor · doi:10.12659/msm.903602 · Cited by 15 · see citing works

Comprehensive analyses of DNA methylation of the TIMP3 promoter in placentas from early-onset and late-onset preeclampsia

Cruz, J. D. O., Mamede, I., Sandrim, V. C., & Luizon, M. R. (2021) · Placenta · doi:10.1016/j.placenta.2021.12.003 · Cited by 15 · see citing works

Reduced methylation downregulates CD39/ENTPD1 and ZDHHC14 to suppress trophoblast cell proliferation and invasion: Implications in preeclampsia

Zhu, L., Lyu, R., Kong, L., & Li, X. (2018) · Pregnancy Hypertension · doi:10.1016/j.preghy.2018.03.012 · Cited by 15 · see citing works

The von Hippel Lindau tumour suppressor gene is a novel target of E2F4-mediated transcriptional repression in preeclampsia

Alahari, S., Garcia, J., Post, M., & Caniggia, I. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.07.016 · Cited by 14 · see citing works

Proteomic analysis of knock-down HLA-G in invasion of human trophoblast cell line JEG-3.

Liu, H., Liu, X., Jin, H. Y., Yang, F., Gu, W., & Li, X. (2013) · Europe PMC (PubMed Central) · Cited by 13 · see citing works

Hypomethylation of the miRNA-34a gene promoter is associated with Severe Preeclampsia

Rezaei, M., Eskandari, F., Mohammadpour‐Gharehbagh, A., Harati‐Sadegh, M., Teimoori, B., & Salimi, S. (2018) · Clinical and Experimental Hypertension · doi:10.1080/10641963.2018.1451534 · Cited by 13 · see citing works

Quantification and Application of Potential Epigenetic Markers in Maternal Plasma of Pregnancies with Hypertensive Disorders

Kim, H., Kim, S. H., Lim, J. Y., Kwak, D. W., Park, S., & Ryu, H. M. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms161226201 · Cited by 13 · see citing works

Microparticle source and tissue factor expression in pregnancy

Wong, A. E., Kwaan, H. C., Grobman, W. A., Weiss, I. M., & Wong, C. A. (2015) · Annals of Hematology · doi:10.1007/s00277-015-2355-6 · Cited by 12 · see citing works

Alteration of Delta-like ligand 1 and Notch 1 receptor in various placental disorders with special reference to early onset preeclampsia

Shimanuki, Y., Mitomi, H., Fukumura, Y., Makino, S., Itakura, A., Yao, T., & Takeda, S. (2015) · Human Pathology · doi:10.1016/j.humpath.2015.03.013 · Cited by 12 · see citing works

Hypomethylation of DNA promoter upregulates ADAMTS7 and contributes to HTR-8/SVneo and JEG-3 cells abnormalities in pre-eclampsia

Zhang, L., Zhao, F., Li, C., Li, H., Tang, Q., Chen, Y., Yao, Y., Ding, Z., Xu, Y., Chen, A., et al. (2020) · Placenta · doi:10.1016/j.placenta.2020.02.013 · Cited by 11 · see citing works

Differential Methylation in Promoter Regions of the Genes NR3C1 and HSP90AA1, Involved in the Regulation, and Bioavailability of Cortisol in Leukocytes of Women With Preeclampsia

Torres-Salazar, Q. L., Martínez-López, Y., Reyes-Romero, M. A., Pérez–Morales, R., Sifuentes-Álvarez, A., & Salvador‐Moysén, J. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.00206 · Cited by 11 · see citing works

WNT3 hypomethylation counteracts low activity of the Wnt signaling pathway in the placenta of preeclampsia

Zhang, L., Sang, M., Li, Y., Li, Y., Yuan, E., Yang, L., Shi, W., Yuan, Y., Yang, B., Yang, P., et al. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03941-4 · Cited by 11 · see citing works

Decreased ALCAM expression and promoter hypermethylation is associated with preeclampsia

Wei, L. S., Pan, Y., Tang, Q., Yang, Z., Song, W., Gao, Y., Li, J., Zhang, L., & Liu, S.-G. (2019) · Hypertension Research · doi:10.1038/s41440-019-0337-0 · Cited by 10 · see citing works

Differences in DNA methylation of insulin-like growth factor 2 and cadherin 13 in patients with preeclampsia

van den Berg, C. B., Herzog, E. M., Duvekot, J. J., van der Spek, P. J., Steegers, E. A. P., Stoop, M. P., Willemsen, S. P., & Steegers‐Theunissen, R. P. M. (2020) · Pregnancy Hypertension · doi:10.1016/j.preghy.2020.01.010 · Cited by 10 · see citing works

Preeclampsia-induced alterations in brain and liver gene expression and DNA methylation patterns in fetal mice

Hofsink, N., Dijkstra, D. J., Stojanovska, V., Scherjon, S. A., & Plösch, T. (2022) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174422000344 · Cited by 10 · see citing works

Placental Growth Factor and Fms Related Tyrosine Kinase-1 are Hypomethylated in Preeclampsia Placentae

Dave, K. M., Kaur, L., Randhir, K., Mehendale, S. S., Sundrani, D. P., Chandak, G. R., & Joshi, S. (2021) · Epigenomics · doi:10.2217/epi-2020-0318 · Cited by 10 · see citing works

Genetic variation, intrauterine growth, and adverse pregnancy conditions predict leptin gene DNA methylation in blood at birth and 12 months of age

Barwon Infant Study Investigator Team, Mansell, T., Ponsonby, A., Collier, F., Burgner, D. P., Vuillermin, P., Lange, K., Ryan, J. L., & Saffery, R. (2019) · International Journal of Obesity · doi:10.1038/s41366-019-0472-3 · Cited by 10 · see citing works

Increased tissue factor expression and promoter hypomethylation in preeclampsia placentas in a Chinese population

Liu, R., Ma, Q., Wen, A., Tian, G., Li, M., Wang, W., & Wang, W. (2017) · Pregnancy Hypertension · doi:10.1016/j.preghy.2017.06.008 · Cited by 9 · see citing works

Correlation of amniotic fluid index and placental aquaporin 1 levels in terms of preeclampsia

Ding, H., Ding, Z., Zhao, M., Ji, B., Lei, J., Chen, J., Li, M., Li, M., Chen, Y., & Gao, Q. (2021) · Placenta · doi:10.1016/j.placenta.2021.12.010 · Cited by 9 · see citing works

Comprehensive Analysis of Differently Expressed and Methylated Genes in Preeclampsia

Xu, W., Ru, P., Gu, Z., Zhang, R., Pang, X., Huang, Y., Liu, Z., & Liu, M. (2020) · Computational and Mathematical Methods in Medicine · doi:10.1155/2020/2139270 · Cited by 8 · see citing works

Hypoxia Inducible Factors (HIF1α and HIF3α) are differentially methylated in preeclampsia placentae and are associated with birth outcomes

Kaur, L., Sundrani, D. P., Dave, K., Randhir, K., Mehendale, S. S., Bayyana, S., Kumaran, K., Chandak, G. R., & Joshi, S. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04661-y · Cited by 8 · see citing works

HOXD8/DIAPH2-AS1 epigenetically regulates PAX3 and impairs HTR-8/SVneo cell function under hypoxia

Feng, Y., Wang, J., He, Y., Zhang, H., Jiang, M., Cao, D., & Wang, A. (2019) · Bioscience Reports · doi:10.1042/bsr20182022 · Cited by 8 · see citing works

Prenatal inflammation exposure-programmed hypertension exhibits multi-generational inheritance via disrupting DNA methylome

Guan, X., Dan, G., Yang, Y., Ji, Y., Lai, W., Wang, F., Meng, M., Mo, B., Huang, P., You, T., et al. (2021) · Acta Pharmacologica Sinica · doi:10.1038/s41401-021-00772-8 · Cited by 8 · see citing works

Hypomethylation of CTGF Promoter in Placenta and Peripheral Blood of Pre-eclampsia Women

Zhang, L., Zhao, F., Yang, C., Tang, Q., Zhang, R., Li, J., Chen, A., Hou, L., & Liu, S. (2020) · Reproductive Sciences · doi:10.1007/s43032-019-00038-z · Cited by 6 · see citing works

Effect of 14-3-3 tau protein on differentiation in BeWo choriocarcinoma cells

Cheng, Y., Hu, R. H., Jin, H., Ma, K., Zhou, S., Cheng, H., Ma, D., & Li, X. (2009) · Placenta · doi:10.1016/j.placenta.2009.10.002 · Cited by 5 · see citing works

Immunological dysregulation in preeclampsia: Pathogenesis and clinical implications

Qin, Z., & Long, Y. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115314 · Cited by 25 · see citing works

Epigenetic landscape of placental tissue in preeclampsia: a systematic review of DNA methylation profiles

Zaki‐Dizaji, M., Ebrahimi, A., Saeedinia, R., & Heidary, Z. (2025) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-025-07950-0 · Cited by 9 · see citing works

From Pregnancy to Breastfeeding: The Role of Maternal Exercise in Preventing Childhood Obesity

Calcaterra, V., Cena, H., Pirazzi, A., Sottotetti, F., Cordaro, E., Cavallo, C., Milanta, C., Masri, D. E., Conti, M. V., Vandoni, M., et al. (2025) · Nutrients · doi:10.3390/nu17040660 · Cited by 12 · see citing works

Reassessing the Role of Tissue Factor Pathway Inhibitor 2 in Neoplastic and Non-Neoplastic Lesions

Kobayashi, H., Shigetomi, H., & Imanaka, S. (2025) · Cancers · doi:10.3390/cancers17091447 · Cited by 5 · see citing works

DNA Methylation‐Induced BNIP3P1 Expression Promotes Pre‐Eclampsia Progression via the miR‐128‐3p/BNIP3 Axis

Zhang, Q., Zheng, H., & Zhang, M. (2025) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.70307 · Cited by 4 · see citing works

Liquid Biopsy and Single-Cell Technologies in Maternal–Fetal Medicine: A Scoping Review of Non-Invasive Molecular Approaches

Monroy-Muñoz, I. E., Torres‐Torres, J., Rojas‐Zepeda, L., Villafán-Bernal, J. R., y Sosa, S. E., Baca, D., Camacho‐Martinez, Z. A., Duran, J. P., Solis‐Paredes, J. M., Estrada‐Gutiérrez, G., et al. (2025) · Diagnostics · doi:10.3390/diagnostics15162056 · Cited by 4 · see citing works

First Trimester Ultrasound Soft Markers in a Fetus: Genetic Associations and Diagnostic Implications

Mangla, M., & Kumar, N. (2025) · Maternal-Fetal Medicine · doi:10.1097/fm9.0000000000000301 · Cited by 4 · see citing works

The Role of microRNA-210 in the Pathogenesis and Diagnosis of Preeclampsia—A Systematic Review

Cretu, O.-E., Dîrlău, A.-A., Neacşu, A., Nenciu, A. E., & Ceauşu, I. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14217593 · Cited by 3 · see citing works

TET1 modulates trophoblast function by regulation of ODC1 in preeclampsia

Fan, C., Kang, Y., Fang, Z., Liu, L., Wang, C., Zhao, M., Xiao, L., & Zhang, C. (2025) · Scientific Reports · doi:10.1038/s41598-025-22116-w · Cited by 3 · see citing works

Differential gene expression profiling of ectopic endometrium reveals key molecular pathways in endometriosis pathogenesis

Rai, G., Ashish, A., Rai, S., Mishra, S., Singh, S., & Singh, R. (2026) · Molecular Biology Reports · doi:10.1007/s11033-026-11521-7 · Cited by 3 · see citing works

Impacts of PM 2.5 on stillbirth and the potential mechanism: a narrative review

Li, Z., Liu, R., & Zhang, E. (2025) · Reviews on Environmental Health · doi:10.1515/reveh-2025-0090 · Cited by 2 · see citing works

Epigenetic changes associated with multi-generational trauma: characterization, mechanisms, and therapeutics

Kac, E., Qi, Q., & Ryznar, R. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1769422 · Cited by 1 · see citing works

MeCP2 attenuates inflammation and regulates T cell phenotype via SFRP4 suppression in preeclampsia

Peng, M., Nie, Y., Luo, Y., Nkoua, G. D. M., Zhang, S., Liu, H., Zhang, W., Xiao, S., Zhou, Y., Lai, W., et al. (2025) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2025.112637 · Cited by 1 · see citing works

Correction: DNA methylation landscape in pregnancyinduced hypertension: progress and challenges

Deng, F., Lei, J., Qiu, J., Zhao, C., Wang, X., Li, M., Sun, M., Zhang, M., & Gao, Q. (2024) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-024-01270-2 · Cited by 1 · see citing works

A Systematic Review of Sterile Intrauterine Inflammation, Immune-Metabolic Cues, and Epigenetic Programming: The Hidden Path to Preterm Birth

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ADIPOQ polymorphisms and haplotypes affect circulating adiponectin levels and their association with gestational hypertension and preeclampsia

de Castro, R. N. F., Pereira, D. A., Cruz, J. D. O., Palei, A. C., Machado, J. D. S. R., Cavalli, R. D., Tanus-Santos, J. E., Sandrim, V. C., & Luizon, M. R. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2025.1736993

Distinct DNA methylation signatures in maternal blood reveal unique immune cell shifts in preeclampsia and the pregnancy-postpartum transition

Jamshed, L., Smith, K. W., & Wilson, S. L. (2026) · PLoS ONE · doi:10.1371/journal.pone.0343041

Epigenetic Modifications of Umbilical Cord Blood and Preeclampsia: a Systematic Review and Metanalysis ProtocolPreprint

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Circulating cell-free DNA in preeclampsia: predictive potential and insights into pathogenesis

Dong, H., Zhang, Y., & Zhang, B. (2026) · European journal of medical research · doi:10.1186/s40001-026-04238-7

Folic acid intake, genetic variations, and DNA methylation in hypertensive disorders of pregnancy: a prospective cohort and epigenome-wide association study

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Co-trimoxazole-induced reproductive toxicity and placental-barrier disruption: impact on cell-cell junctions and ERK signaling pathway

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Epigenetic, environmental, and sex-specific programming of long-term health in Assisted Reproductive Technologies–conceived offspring

Rhon‐Calderón, E. A., Hemphill, C. N., & Bartolomei, M. S. (2026) · Biology of Reproduction · doi:10.1093/biolre/ioag137

Hubungan Pola Sidik Jari dengan Kejadian Hipertensi pada Komunitas Akademik Kampus X di Jakarta Pusat

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Epigenome-wide placental methylation landscapes in relation to antenatal depressive symptoms

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Cardiometabolic Complications in Pregnancy and Biological Ageing in the Offspring: A Systematic Review and Meta‐Analysis

Mekonnen, E. G., Bianco‐Miotto, T., Liu, K., & Grieger, J. A. (2026) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.70206

DNA methylation profiling of human placentas reveals promoter hypomethylation of multiple genes in early-onset preeclampsia

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Detection of global DNA methylation and paternally imprinted H19 gene methylation in preeclamptic placentas

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DNA methylation profiles in preeclampsia and healthy control placentas

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Epigenetic Placental Programming of Preeclampsia

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The Role of Epigenetics in Placental Development and the Etiology of Preeclampsia

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