SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis

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NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

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Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis

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Activation of the p62–Keap1–NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

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NRF2 and the Hallmarks of Cancer

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Cysteine depletion induces pancreatic tumor ferroptosis in mice

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Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11

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BAP1 links metabolic regulation of ferroptosis to tumour suppression

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ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation

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The Roles of NRF2 in Modulating Cellular Iron Homeostasis

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Cancer related mutations in <i>NRF2</i> impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

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RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer

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Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis

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A sensitive assay for dNTPs based on long synthetic oligonucleotides, EvaGreen dye and inhibitor-resistant high-fidelity DNA polymerase

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Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer

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Ferroptosis, radiotherapy, and combination therapeutic strategies

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Clockophagy is a novel selective autophagy process favoring ferroptosis

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Metformin induces Ferroptosis by inhibiting UFMylation of SLC7A11 in breast cancer

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Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma

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Role of Nrf2 and Its Activators in Respiratory Diseases

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A Convergence-Based Framework for Cancer Drug Resistance

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3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis

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Acetaminophen sensitizing erastin‐induced ferroptosis via modulation of Nrf2/heme oxygenase‐1 signaling pathway in non‐small‐cell lung cancer

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The Nrf2 induction prevents ferroptosis in Friedreich's Ataxia

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Nrf2 is a potential therapeutic target in radioresistance in human cancer

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Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT

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Increased xCT Expression Correlates With Tumor Invasion and Outcome in Patients With Glioblastomas

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BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response

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Effects of Selenium Nanoparticles Combined With Radiotherapy on Lung Cancer Cells

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Overexpression of SlC7A11: A Novel Oncogene and an Indicator of Unfavorable Prognosis for Liver Carcinoma

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Nrf2 is Useful for Predicting the Effect of Chemoradiation Therapy on Esophageal Squamous Cell Carcinoma

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SLC7A11 Reduces Laser-Induced Choroidal Neovascularization by Inhibiting RPE Ferroptosis and VEGF Production

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SETD2 epidermal deficiency promotes cutaneous wound healing via activation of AKT/mTOR Signalling

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The Role of Cystine/Glutamate Antiporter SLC7A11/xCT in the Pathophysiology of Cancer

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Thirty years of NRF2: advances and therapeutic challenges.

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Targeting ferroptosis in acute kidney injury

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SLC7A11 as a Gateway of Metabolic Perturbation and Ferroptosis Vulnerability in Cancer

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Ferroptosis as a potential target for cancer therapy

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Mechanisms of radiotherapy resistance and radiosensitization strategies for esophageal squamous cell carcinoma

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Targeting fatty acid synthase modulates sensitivity of hepatocellular carcinoma to sorafenib via ferroptosis

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STC2 activates PRMT5 to induce radioresistance through DNA damage repair and ferroptosis pathways in esophageal squamous cell carcinoma

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Ferroptosis in lung cancer: a novel pathway regulating cell death and a promising target for drug therapy

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The Role of SLC7A11 in Cancer: Friend or Foe?

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Ferroptosis, Necroptosis, and Pyroptosis in Gastrointestinal Cancers: The Chief Culprits of Tumor Progression and Drug Resistance

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Targeting SIRT3 sensitizes glioblastoma to ferroptosis by promoting mitophagy and inhibiting SLC7A11

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Deregulated transcription factors in cancer cell metabolisms and reprogramming

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Ferritinophagy is involved in Bisphenol A-induced ferroptosis of renal tubular epithelial cells through the activation of the AMPK-mTOR-ULK1 pathway

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The amino acid transporter SLC7A11-mediated crosstalk implicated in cancer therapy and the tumor microenvironment

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The Cancer Antioxidant Regulation System in Therapeutic Resistance

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The interplay of oncogenic signaling, oxidative stress and ferroptosis in cancer

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Amino acid transporters within the solute carrier superfamily: Underappreciated proteins and novel opportunities for cancer therapy

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Targeting stearoyl-coa desaturase enhances radiation induced ferroptosis and immunogenic cell death in esophageal squamous cell carcinoma

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miRNAs role in bladder cancer pathogenesis and targeted therapy: Signaling pathways interplay – A review

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Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis

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Protein modification and degradation in ferroptosis

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Ferroptosis and its role in skeletal muscle diseases

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Ferroptosis, necroptosis, and pyroptosis in cancer: Crucial cell death types in radiotherapy and post-radiotherapy immune activation

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RNA m6A modification in ferroptosis: implications for advancing tumor immunotherapy

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Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosis

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Nrf2‐Mediated Ferroptosis Inhibition Exerts a Protective Effect on Acute‐on‐Chronic Liver Failure

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Depletion of SOD2 enhances nasopharyngeal carcinoma cell radiosensitivity via ferroptosis induction modulated by DHODH inhibition

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Inhibition of NRF2 enhances the acute myeloid leukemia cell death induced by venetoclax via the ferroptosis pathway

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Artemisinin inhibits neuronal ferroptosis in Alzheimer’s disease models by targeting KEAP1

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Ferroptosis in gastrointestinal cancer: from mechanisms to implications

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Targeting estrogen-regulated system xc− promotes ferroptosis and endocrine sensitivity of ER+ breast cancer

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Cooperation effects of radiation and ferroptosis on tumor suppression and radiation injury

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The KEAP1-NRF2 System and Esophageal Cancer

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Ferulic Acid Mitigates Growth and Invasion of Esophageal Squamous Cell Carcinoma through Inducing Ferroptotic Cell Death

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Reinforcing the immunogenic cell death to enhance cancer immunotherapy efficacy

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Disulfidptosis, A Novel Cell Death Pathway: Molecular Landscape and Therapeutic Implications

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USP13 facilitates a ferroptosis-to-autophagy switch by activation of the NFE2L2/NRF2-SQSTM1/p62-KEAP1 axis dependent on the KRAS signaling pathway

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Targeting GSTP1-dependent ferroptosis in lung cancer radiotherapy: Existing evidence and future directions

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ARE-PROTACs Enable Co-degradation of an Nrf2–MafG Heterodimer

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The Multi-Faceted Consequences of NRF2 Activation throughout Carcinogenesis

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Emerging role of ferroptosis in glioblastoma: Therapeutic opportunities and challenges

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Contribution of Lipid Oxidation and Ferroptosis to Radiotherapy Efficacy

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Repurposed pizotifen malate targeting NRF2 exhibits anti-tumor activity through inducing ferroptosis in esophageal squamous cell carcinoma

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Nrf2 and Ferroptosis: Exploring Translational Avenues for Therapeutic Approaches to Neurological Diseases

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Ferroptosis contributing to cardiomyocyte injury induced by silica nanoparticles via miR-125b-2-3p/HO-1 signaling

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Butylphthalide inhibits ferroptosis and ameliorates cerebral Ischaemia–Reperfusion injury in rats by activating the Nrf2/HO-1 signalling pathway

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NFE2L2 and ferroptosis resistance in cancer therapy

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lncRNA BBOX1-AS1 silencing inhibits esophageal squamous cell cancer progression by promoting ferroptosis via miR-513a-3p/SLC7A11 axis

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Suppression of the SLC7A11/glutathione axis causes ferroptosis and apoptosis and alters the mitogen-activated protein kinase pathway in nasopharyngeal carcinoma

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Counteraction of Myocardial Ferritin Heavy Chain Deficiency by Heme Oxygenase-1

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Brusatol induces ferroptosis in oesophageal squamous cell carcinoma by repressing GSH synthesis and increasing the labile iron pool via inhibition of the NRF2 pathway

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Exosome-mediated metabolic reprogramming: Implications in esophageal carcinoma progression and tumor microenvironment remodeling

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Clobetasol propionate, a Nrf-2 inhibitor, sensitizes human lung cancer cells to radiation-induced killing via mitochondrial ROS-dependent ferroptosis

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Ginsenoside Rg5 promotes wound healing in diabetes by reducing the negative regulation of SLC7A11 on the efferocytosis of dendritic cells

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ML385 promotes ferroptosis and radiotherapy sensitivity by inhibiting the NRF2-SLC7A11 pathway in esophageal squamous cell carcinoma

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Network Pharmacology Identifies Therapeutic Targets and the Mechanisms of Glutathione Action in Ferroptosis Occurring in Oral Cancer

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Danggui Buxue Tang improves therapeutic efficacy of doxorubicin in triple negative breast cancer via ferroptosis

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Emerging trends of phytochemicals as ferroptosis modulators in cancer therapy

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Natural plant-derived nanovesicles for effective psoriasis therapy via dual modulation of IL-17 and NRF2 pathway

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Targeting YBX1‐m5C mediates RNF115 mRNA circularisation and translation to enhance vulnerability of ferroptosis in hepatocellular carcinoma

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Comprehensive Analysis of YTHDF1 Immune Infiltrates and ceRNA in Human Esophageal Carcinoma

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Ferrostatin-1 inhibits fibroblast fibrosis in keloid by inhibiting ferroptosis

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Secreted Apoe rewires melanoma cell state vulnerability to ferroptosis

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Recent advances of ferroptosis in tumor: From biological function to clinical application.

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Magnolol against enterovirus 71 by targeting Nrf2-SLC7A11-GSH pathway

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Flavonoids attenuate cancer metabolism by modulating Lipid metabolism, amino acids, ketone bodies and redox state mediated by Nrf2

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Anaplastic thyroid cancer cells reduce CD71 levels to increase iron overload tolerance

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Ononin triggers ferroptosis-mediated disruption in the triple negative breast cancer both in vitro and in vivo

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Downregulation of lncRNA SLC7A11-AS1 decreased the NRF2/SLC7A11 expression and inhibited the progression of colorectal cancer cells

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AhR signaling modulates Ferroptosis by regulating SLC7A11 expression

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Ferroptosis contributes to the progression of female-specific neoplasms, from breast cancer to gynecological malignancies in a manner regulated by non-coding RNAs: Mechanistic implications

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Dietary Phytochemicals Targeting Nrf2 to Enhance the Radiosensitivity of Cancer

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NRF2 Antagonizes HIV-1 Tat and Methamphetamine-Induced BV2 Cell Ferroptosis by Regulating SLC7A11

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Endometrial stem cells alleviate cisplatin-induced ferroptosis of granulosa cells by regulating Nrf2 expression

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Competing endogenous RNA networks and ferroptosis in cancer: novel therapeutic targets

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The main active components of Prunella vulgaris L. alleviate myocardial ischemia-reperfusion injury by inhibiting oxidative stress and ferroptosis via the NRF2/GPX4 pathway

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Glutamine metabolism in tumor metastasis: Genes, mechanisms and the therapeutic targets

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Single-cell transcriptomic sequencing data reveal aberrant DNA methylation in SMAD3 promoter region in tumor-associated fibroblasts affecting molecular mechanism of radiosensitivity in non-small cell lung cancer

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Brusatol induced ferroptosis in osteosarcoma cells by modulating the Keap1/Nrf2/SLC7A11 signaling pathway

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Nickel oxide nanoparticles induce developmental neurotoxicity in zebrafish by triggering both apoptosis and ferroptosis

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Structural characterization and ferroptosis-related immunomodulatory of a novel exopolysaccharide isolated from marine fungus Aspergillus medius

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Ferroptosis and cancer: when iron turns against tumors

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Ferroptosis‐Related lncRNA Signature Correlates with the Prognosis, Tumor Microenvironment, and Therapeutic Sensitivity of Esophageal Squamous Cell Carcinoma

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