The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
The role of inflammation in the development of epilepsy
Open accessAbstract
Epilepsy, a neurological disease characterized by recurrent seizures, is often associated with a history of previous lesions in the nervous system. Impaired regulation of the activation and resolution of inflammatory cells and molecules in the injured neuronal tissue is a critical factor to the development of epilepsy. However, it is still unclear as to how that unbalanced regulation of inflammation contributes to epilepsy. Therefore, one of the goals in epilepsy research is to identify and elucidate the interconnected inflammatory pathways in systemic and neurological disorders that may further develop epilepsy progression. In this paper, inflammatory molecules, in neurological and systemic disorders (rheumatoid arthritis, Crohn's, Type I Diabetes, etc.) that could contribute to epilepsy development, are reviewed.Understanding the neurobiology of inflammation in epileptogenesis will contribute to the development of new biomarkers for better screening of patients at risk for epilepsy and new therapeutic targets for both prophylaxis and treatment of epilepsy.
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Cites
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Cited by
Microbiota-gut brain axis involvement in neuropsychiatric disorders
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Ambient air pollution and epileptic seizures: A panel study in Australia
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NLRP1 inflammasome in neurodegenerative disorders: From pathology to therapies
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Metadata
- Authors
- Rana, A., & Musto, A. E.
- Venue
- Journal of Neuroinflammation
- Published
- 2018-05-15
- Volume
- 15
- Issue
- 1
- Pages
- 144-144
- ISSN
- 1742-2094 (ISSN-L)
- OpenAlex
- W2804721038
- Cited by
- 709
- References
- 10
- FWCI
- 35.03
- Type
- journal article
- Language
- en
- Open access
- gold
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