The DOI matches its Crossref record; 108 of the 108 references it cites were found in a registry or an index.
Necroptosis: a regulated inflammatory mode of cell death
Open accessAbstract
Programmed cell death has a vital role in embryonic development and tissue homeostasis. Necroptosis is an alternative mode of regulated cell death mimicking features of apoptosis and necrosis. Necroptosis requires protein RIPK3 (previously well recognized as regulator of inflammation, cell survival, and disease) and its substrate MLKL, the crucial players of this pathway. Necroptosis is induced by toll-like receptor, death receptor, interferon, and some other mediators. Shreds of evidence based on a mouse model reveals that deregulation of necroptosis has been found to be associated with pathological conditions like cancer, neurodegenerative diseases, and inflammatory diseases. In this timeline article, we are discussing the molecular mechanisms of necroptosis and its relevance to diseases.
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Cites
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Cited by
Karki, R., Sharma, B. R., Tuladhar, S., Williams, E. P., Zalduondo, L., Samir, P., Zheng, M., Sundaram, B., Banoth, B., Malireddi, R. K. S., et al. (2021) · Cell · doi:10.1016/j.cell.2020.11.025 · Cited by 1,734
NLRP3 inflammasome activation and cell death
Huang, Y., Xu, W., & Zhou, R. (2021) · Cellular & Molecular Immunology · doi:10.1038/s41423-021-00740-6 · Cited by 1,527
Mustafa, M., Ahmad, R., Tantry, I. Q., Ahmad, W., Siddiqui, S., Alam, M., Abbas, K., Moinuddin, Hassan, M. I., Habib, S., et al. (2024) · Cells · doi:10.3390/cells13221838 · Cited by 595
Programmed Cell Death Tunes Tumor Immunity
Liu, J., Hong, M., Li, Y., Chen, D., Wu, Y., & Hu, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.847345 · Cited by 316
Cell death mechanisms in eukaryotes
Nirmala, J. G., & Lopus, M. (2020) · Cell Biology and Toxicology · doi:10.1007/s10565-019-09496-2 · Cited by 267
Metadata
- Authors
- Dhuriya, Y. K., & Sharma, D.
- Venue
- Journal of Neuroinflammation
- Published
- 2018-07-06
- Volume
- 15
- Issue
- 1
- Pages
- 199-199
- ISSN
- 1742-2094 (ISSN-L)
- OpenAlex
- W2851271116
- Cited by
- 718
- References
- 108
- FWCI
- 14.60
- Type
- journal article
- Language
- en
- Open access
- gold
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