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Impairment of autophagy in the central nervous system during lipopolysaccharide-induced inflammatory stress in mice
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Low levels of IL-1β stimulate autophagolysosomal function and attenuate inflammation in cell cultures.
“low levels of IL-1β stimulate autophagolysosomal function and attenuate inflammation in cell cultures”
Higher IL-1β concentrations (> 200 pg/mL) have the opposite effect to low levels on autophagolysosomal function and inflammation.
“while higher cytokine concentrations (> 200 pg/mL) have the opposite effect [60, 61].”
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BackgroundA metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
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Metadata
- Authors
- Francois, A., Terro, F., Quellard, N., Fernandez, B., Chassaing, D., Janet, T., Bilan, A. R., Paccalin, M., & Page, G.
- Venue
- Molecular Brain
- Published
- 2014-08-27
- Volume
- 7
- Issue
- 1
- ISSN
- 1756-6606
- PMC
- PMC4237961
- Cited by
- 62
- References
- 15
- Language
- en
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