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Cited by 16Thyroid Disorders and TreatmentsThyroid and Parathyroid SurgeryPsychological Treatments and Assessments

The effectiveness of cognitive- behavioral therapy on quality of life in women with hypothyroidism in the reproductive age: a randomized controlled trial

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Rezaei, Sohaila, Abedi, Parvin, Maraghi, Elham, Hamid, Najmeh, Rashidi, Homaira·2020·Thyroid Research
DOI 10.1186/s13044-020-00080-zPMC PMC7238494
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Abstract

Background: Worldwide, hypothyroidism affects 3.7% of the population, and is associated with impaired quality of life. This study aimed to evaluate the effect of cognitive- behavioral therapy (CBT) on the quality of life in women with hypothyroidism. Methods: 96 women with hypothyroidism randomly allocated into two groups: CBT group (n = 48) and control group (n = 48). Women in the CBT group were classified into four sub-groups of 12, and each sub-group received eight sessions of counseling (each session lasting 90 min). We collected data using a demographic questionnaire and the 36-Item Short Form Health Survey (SF 36) for measuring the quality of life. We used the independent t-test, chi-square test and ANCOVA to analyze the data. Results: Five women from each group withdrew from the study, leaving 43 women in each group. The scores on physical functioning, physical health problems, social functioning and pain improved in the CBT group after the intervention, but the differences between the two groups were not significant. The scores on emotional health, emotional health problems, energy and emotions, and general health were significantly better in the CBT group than those in the control group (p < 0.05). Conclusion: Counseling using CBT can improve some aspects of quality of life, including emotional health, emotional health problems, energy and general health in patients with hypothyroidism. Trial registration number: Iranian Registry for Clinical Trials: 20190323043101 N1. https://www.irct.ir/

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  • In hypothyroid women on LT4 with SF36 QoL score <60, cognitive behavioral therapy improved scores for emotional health, energy, and general health to a greater extent than in controls.

    “Hypothyroid women on LT4 (score <60 on the SF36 QoL questionnaire) were randomized to cognitive behavioral therapy (CBT) (8 weekly sessions each lasting 90 minutes, in a group of 12) or no specific intervention; CBT improved scores for emotional health, energy, and general health to a greater extent than in controls [71].”

    From T4+T3 Combination Therapy: An Unsolved Problem of Increasing Magnitude and Complexity (2021) · cites this paper as [71]

    The Methods (page not available) specify an SF-36 score below 60, medication for hypothyroidism, eight weekly 90-minute CBT sessions, and no intervention for controls. The Results (page not available) report significantly greater improvements in emotional health, energy and emotions, and general health with CBT. The paper does not specify that the trial participants’ medication was LT4, so that detail is unsupported. (LLM, conf=0.88)

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Authors
Rezaei, S., Abedi, P., Maraghi, E., Hamid, N., & Rashidi, H.
Affiliations
  • Ahvaz Jundishapur University of Medical Sciences (IR)
  • Shahid Chamran University of Ahvaz (IR)
Corresponding author
Abedi, Parvin
ORCID
Venue
Thyroid Research
Publisher
Springer Science and Business Media LLC
Published
2020-05-20
Volume
13
Issue
1
Pages
6-6
ISSN
1756-6614 (ISSN-L)
DOI
10.1186/s13044-020-00080-z
PMC
PMC7238494
OpenAlex
W3026846602
Cited by
16
References
22
Citations by year
2026: 3 · 2025: 2 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 1
FWCI
2.07
Type
journal article
Language
en
Open access
Licence
Locations
  • Thyroid Research (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Ahvaz Jundishapur University of Medical Sciences (1397.968)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
  • Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
  • Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
Keywords
cognitive behavioral therapy, hypothyroidism, quality of life, women, reproductive age, emotional well-being, psychological well-being, counseling intervention

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