The cognitive behavioral therapy causes an improvement in quality of life in patients with chronic musculoskeletal pain
Open accessAbstract
Chronic pain causes functional incapacity and compromises an individual's affective, social, and economic life. OBJECTIVE: To study the cognitive behavioral therapy (CBT) effectiveness in a group of patients with chronic pain. METHODS: A randomized clinical trial with two parallel groups comprising 93 patients with chronic pain was carried out. Forty-eight patients were submitted to CBT and 45 continued the standard treatment. The visual analogue, hospital anxiety and depression, and quality of life SF-36 scales were applied. Patients were evaluated before and after ten weeks of treatment. RESULTS: When the Control Group and CBT were compared, the latter presented reduction of depressive symptoms (p=0.031) and improvement in the domains 'physical limitations' (p=0.012), 'general state of health' (p=0.045), and 'limitations by emotional aspects' (p=0.025). CONCLUSIONS: The CBT was effective and it has caused an improvement in more domains of quality of life when compared to the Control Group, after ten weeks of treatment.
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For Castro 2012, random sequence generation was at unclear risk of bias.
“It was a randomized clinical trial with parallel groups.”
From Psychological therapies for the management of chronic pain (excluding headache) in adults (2020) · cites this paper as Castro 2012
For Castro 2012, treatment expectations was at unclear risk of bias.
“Not assessed”
From Psychological therapies for the management of chronic pain (excluding headache) in adults (2020) · cites this paper as Castro 2012
For Castro 2012, incomplete outcome data was at low risk of bias.
“Attrition < 10% but no details provided regarding handling of missing data.”
From Psychological therapies for the management of chronic pain (excluding headache) in adults (2020) · cites this paper as Castro 2012
For Castro 2012, allocation concealment was at unclear risk of bias.
“No description”
From Psychological therapies for the management of chronic pain (excluding headache) in adults (2020) · cites this paper as Castro 2012
For Castro 2012, blinding of outcome assessment was at unclear risk of bias.
“No description”
From Psychological therapies for the management of chronic pain (excluding headache) in adults (2020) · cites this paper as Castro 2012
The Methods describe an independent person who organized the randomization list, but do not say whether outcome assessors were blinded. The passages on outcome measures and evaluations also do not assess risk of bias, so our copy cannot verify the citing document’s ‘unclear risk’ rating. (LLM, conf=0.70)
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From Psychological therapies for the management of chronic pain (excluding headache) in adults (2020) · cites this paper as Castro 2012
The Methods section describes the trial and its primary and secondary endpoints, but does not state whether it was pre-registered. A search of our copy for registration, a trial registry, and a prespecified protocol found no passage establishing non-registration or assessing selective-reporting risk. Page numbers were not available in our copy. (LLM, conf=0.72)
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Cites
HUSKISSON, E. C. (1974) · The Lancet · doi:10.1016/s0140-6736(74)90884-8 · Cited by 4,533 · see citing works
Lecrubier, Y., Sheehan, D., Weiller, E., Amorim, P., Bonora, I., Sheehan, K. H., Janavs, J., & Dunbar, G. (1997) · European Psychiatry · doi:10.1016/s0924-9338(97)83296-8 · Cited by 3,513 · see citing works
Morley, S., Eccleston, C., & Williams, A. (1999) · Pain · doi:10.1016/s0304-3959(98)00255-3 · Cited by 1,597 · see citing works
Amorim, P. (2000) · Brazilian Journal of Psychiatry · doi:10.1590/s1516-44462000000300003 · Cited by 1,075 · see citing works
Smeets, R. J. E. M., Vlaeyen, J. W. S., Kester, A. D. M., & Knottnerus, J. A. (2006) · The Journal of Pain · doi:10.1016/j.jpain.2005.10.011 · Cited by 629 · see citing works
Turner, J. A., Mancl, L., & Aaron, L. A. (2006) · Pain · doi:10.1016/j.pain.2005.11.017 · Cited by 270 · see citing works
Masheb, R. M., Kerns, R. D., Lozano, C., Minkin, M. J., & Richman, S. M. (2008) · Pain · doi:10.1016/j.pain.2008.09.031 · Cited by 244 · see citing works
Redondo, J. R., Justo, C. M., Moraleda, F. V., Velayos, Y. G., Puche, J. J. O., Zubero, J. R., Hernández, T. G., Ortells, L. C., & Pareja, M. Á. V. (2004) · Arthritis Care & Research · doi:10.1002/art.20252 · Cited by 229 · see citing works
King, M., Davidson, O., Taylor, F., Haines, A., Sharp, D., & Turner, R. (2002) · BMJ · doi:10.1136/bmj.324.7343.947 · Cited by 175 · see citing works
McCracken, L. M., MacKichan, F., & Eccleston, C. (2007) · European Journal of Pain · doi:10.1016/j.ejpain.2006.05.004 · Cited by 167 · see citing works
(2002) · PubMed · Cited by 167 · see citing works
Cunha, A. C., Burke, T. N., França, F. J. R., & Marques, A. P. (2008) · Clinics · doi:10.1590/s1807-59322008000600010 · Cited by 152 · see citing works
Koleck, M., Mazaux, J., Rascle, N., & Bruchon‐Schweitzer, M. (2005) · European Journal of Pain · doi:10.1016/j.ejpain.2005.01.003 · Cited by 150 · see citing works
Brief group cognitive-behavioral intervention for temporomandibular disorders
Dworkin, S. F., Turner, J. A., Wilson, L., Massoth, D. L., Whitney, C. W., Huggins, K. H., Burgess, J. A., Sommers, E. E., & Truelove, E. L. (1994) · Pain · doi:10.1016/0304-3959(94)90070-1 · Cited by 145 · see citing works
Impacto da dor na vida de portadores de disfunção temporomandibular
de Oliveira, A. S., Bermudez, C. C., de Souza, R. A., Souza, C. M. F., Dias, E. M., Castro, C. E. D. S., & Bérzin, F. (2003) · Journal of Applied Oral Science · doi:10.1590/s1678-77572003000200010 · Cited by 76 · see citing works
Validacao da escala hospitalar de ansiedade e depressao (HAD) em pacientes epilepticos ambulatoriais
Botega, N. J., Pondé, M. P., Medeiros, P., Lima, M. G., & Guerreiro, C. A. M. (1998) · Jornal Brasileiro de Psiquiatria · Cited by 73 · see citing works
Impact of chronic disease on quality of life in the Bella Coola Valley
Thommasen, H. V., & Zhang, W. (2006) · Rural and Remote Health · doi:10.22605/rrh528 · Cited by 64 · see citing works
Is cognitive behaviour therapy for chronic fatigue syndrome also effective for pain symptoms?
Knoop, H., Stulemeijer, M., Prins, J. B., van der Meer, J. W. M., & Bleijenberg, G. (2007) · Behaviour Research and Therapy · doi:10.1016/j.brat.2007.03.002 · Cited by 54 · see citing works
Back Pain in Direct Patient Care Providers: Early Intervention with Cognitive Behavioral Therapy
Menzel, N. N., & Robinson, M. E. (2006) · Pain Management Nursing · doi:10.1016/j.pmn.2006.02.002 · Cited by 35 · see citing works
Ciaramella, A., Grosso, S., Poli, P., Gioia, A., Inghirami, S., Massimetti, G., & Conti, L. (2003) · European Journal of Pain · doi:10.1016/s1090-3801(03)00062-4 · Cited by 29 · see citing works
Sintomas depressivos e ansiedade em pacientes com cefaléia do tipo tensional crônica e episódica
Matta, A. P. D. C., & Filho, P. F. M. (2003) · Arquivos de Neuro-Psiquiatria · doi:10.1590/s0004-282x2003000600019 · Cited by 19 · see citing works
Conceitos culturais e a experiência dolorosa
Pimenta, C. A. D. M. (1998) · Revista da Escola de Enfermagem da USP · doi:10.1590/s0080-62341998000200011 · Cited by 10 · see citing works
Flagged first, then by citations
Research works printed but not linked: 3
- Oliveira AS, Bermudez CC, Souza RA, Souza CM, Dias EM, Castro CE. Pain impact on life of patients with temporomandibular disorder. J Appl Oral Sci 2003;11:138-143.
- Bruch A, Rosa JL, Leopoldo AC, et al. Relação de distúrbios mentais em uma população com doenças musculoesqueléticas ou reumatológicas. Rev Dor 2006;7:875-881.
- Ciconelli RM. Tradução para o português e validação do questionário genérico de avaliação de qualidade de vida "Medical outcomes study 36-item short-form health survey (SF-36)" [thesis]. São Paulo, SP: Universidade Federal de São Paulo, Escola Paulista de Medicina; 1997.
Cited by
Sorted by citations
Psychological therapies for the management of chronic pain (excluding headache) in adults
Williams, A. C. D. C., Eccleston, C., & Morley, S. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007407.pub3 · Cited by 1,634 · see citing works
Psychological therapies for the management of chronic pain (excluding headache) in adults
Williams, A. C. D. C., Fisher, E., Hearn, L., & Eccleston, C. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007407.pub4 · Cited by 605 · see citing works
Chronic Pain and Cognitive Behavioral Therapy: An Integrative Review
Knoerl, R., Lavoie Smith, E. M., & Weisberg, J. (2016) · Western Journal of Nursing Research · doi:10.1177/0193945915615869 · Cited by 194 · see citing works
Opioid Prescription, Morbidity, and Mortality in United States Dialysis Patients
Kimmel, P. L., Fwu, C., Abbott, K. C., Eggers, A. W., Kline, P. P., & Eggers, P. W. (2017) · Journal of the American Society of Nephrology · doi:10.1681/asn.2017010098 · Cited by 120 · see citing works
Cupping therapy and chronic back pain: systematic review and meta-analysis
Moura, C. D. C., Chaves, É. D. C. L., Cardoso, A. C., Nogueira, D., Corrêa, H. P., & Chianca, T. (2018) · Revista Latino-Americana de Enfermagem · doi:10.1590/1518-8345.2888.3094 · Cited by 77 · see citing works
Cognitive-behavioral therapy for patients with chronic pain
Lim, J.-A., Choi, S., Lee, W. J., Jang, J. H., Moon, J. Y., Kim, Y. C., & Kang, D. (2018) · Medicine · doi:10.1097/md.0000000000010867 · Cited by 81 · see citing works
Cajanding, R. J. M. (2016) · Applied Nursing Research · doi:10.1016/j.apnr.2016.01.002 · Cited by 74 · see citing works
Opioid Prescription, Morbidity, and Mortality in US Transplant Recipients
Abbott, K. C., Fwu, C., Eggers, P. W., Eggers, A. W., Kline, P. P., & Kimmel, P. L. (2018) · Transplantation · doi:10.1097/tp.0000000000002057 · Cited by 43 · see citing works
McSwan, J., Gudin, J. A., Song, X.-J., Plapler, P. G., Betteridge, N., Kechemir, H., Turudic, I. I., & Pickering, G. P. (2021) · Journal of Pain Research · doi:10.2147/jpr.s321037 · Cited by 41 · see citing works
Fariello, J. Y., & Moldwin, R. (2015) · PubMed Central · doi:10.3978/j.issn.2223-4683.2015.10.09 · Cited by 31 · see citing works
Boersen, Z., de Kok, L., van der Zanden, M., Braat, D. D. M., Oosterman, J. M., & Nap, A. W. (2021) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2021.01.010 · Cited by 25 · see citing works
Rababa, M., Alhawatmeh, H. N., Ali, N. M. A., & Kassab, M. I. (2020) · Cognitive Therapy and Research · doi:10.1007/s10608-020-10167-4 · Cited by 23 · see citing works
Hernández, M. E. H., Waller, G., & Hardy, G. E. (2020) · The Cognitive Behaviour Therapist · doi:10.1017/s1754470x20000574 · Cited by 25 · see citing works
Orock, A. M., Louwies, T., Ligon, C. O., Mohammadi, E., & Meerveld, B. G. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113841 · Cited by 23 · see citing works
Prevalence of Chronic Pain in a Large Integrated Healthcare Delivery System in the U.S.A
Lamerato, L. E., Dryer, R. D., Wolff, G. G., Hegeman‐Dingle, R., Mardekian, J., Park, P. W., & Zlateva, G. (2015) · Pain Practice · doi:10.1111/papr.12334 · Cited by 20 · see citing works
Saxena, A., Bhardwaj, N., Chilkoti, G., Malik, A., Thakur, G., Bajaj, M., Banerjee, A., Banerjee, B., & Singhal, A. (2021) · Pain medicine (Malden, Mass.) · doi:10.1093/pm/pnab142 · Cited by 18 · see citing works
Ampiah, P. K., Hendrick, P. A., Moffatt, F., & Ampiah, J. A. (2020) · Musculoskeletal Care · doi:10.1002/msc.1462 · Cited by 20 · see citing works
Anwar, S., Zahid, J., Alexe, C. I., Ghazi, A., Mareș, G., Sheraz, Z., Sánchez‐Gómez, R., Perveen, W., Alexe, D. I., & Gasibat, Q. (2024) · Behavioral Sciences · doi:10.3390/bs14030205 · Cited by 18 · see citing works
Rezaei, S., Abedi, P., Maraghi, E., Hamid, N., & Rashidi, H. (2020) · Thyroid Research · doi:10.1186/s13044-020-00080-z · Cited by 16 · see citing works
Rogers, M., & Lemstra, M. (2016) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s100693 · Cited by 16 · see citing works
Orock, A. M., Louwies, T., Yuan, T., & Meerveld, B. G. (2020) · Neurogastroenterology & Motility · doi:10.1111/nmo.13826 · Cited by 16 · see citing works
Factors involved in patients’ perceptions of self-improvement after chronic pain treatment
Shaikh, M., & Hapidou, E. G. (2018) · Canadian Journal of Pain · doi:10.1080/24740527.2018.1476821 · Cited by 12 · see citing works
Roslyakova, T., Falco, M.-A., & Gauchet, A. (2021) · Psychology & Health · doi:10.1080/08870446.2020.1856844 · Cited by 10 · see citing works
Schmerzsyndrome des Bewegungsapparates bei Kindern und Jugendlichen
Höfel, L., Draheim, N., Häfner, R., & Haas, J. (2016) · Zeitschrift für Rheumatologie · doi:10.1007/s00393-016-0061-y · Cited by 9 · see citing works
Pilot study of a basic individualized cognitive behavioral therapy program for chronic pain in Japan
Hosogoshi, H., Iwasa, K., Fukumori, T., Takagishi, Y., Takebayashi, Y., Adachi, T., Oe, Y., Tairako, Y., Takao, Y., Nishie, H., et al. (2020) · BioPsychoSocial Medicine · doi:10.1186/s13030-020-00176-w · Cited by 9 · see citing works
Orock, A. M., Yuan, T., & Meerveld, B. G. (2021) · Frontiers in Pain Research · doi:10.3389/fpain.2020.609292 · Cited by 10 · see citing works
Orock, A. M., Johnson, A. C., Mohammadi, E., & Meerveld, B. G. (2023) · Neurobiology of Stress · doi:10.1016/j.ynstr.2023.100590 · Cited by 8 · see citing works
Batho, A., Kneale, D., Sutcliffe, K., & Williams, A. C. D. C. (2021) · Pain · doi:10.1097/j.pain.0000000000002242 · Cited by 8 · see citing works
Bogaert, W. V., Putman, K. D., Coppieters, I., Goudman, L., Nijs, J., Moens, M., Buyl, R., Ickmans, K., & Huysmans, E. (2021) · Quality of Life Research · doi:10.1007/s11136-021-02964-5 · Cited by 7 · see citing works
Chabok, H. A., & Ring, D. (2014) · HAND · doi:10.1007/s11552-014-9604-3 · Cited by 5 · see citing works
Hughes, J., Seemann, E. A., George, J. M., & Willis, K. D. (2018) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-018-9568-5 · Cited by 5 · see citing works
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Romagnolli, L., Cória, V. R., Júnior, S. H. N., Sartori, J. E. T., Romanelli, A. D. S., de Oliveira, Ú. C. M., Carvalho, L. G. S., Maritan, B. S., de Fornasari, M. L., Ávila, L. A., et al. (2016) · Revista de Medicina · doi:10.11606/issn.1679-9836.v95i1p12-17 · Cited by 4 · see citing works
Kibret, H., Assefa, N., Eyeberu, A., Debella, A., Getachew, T., DERESSA, A. D., Tamiru, D., Bekele, H., Habte, S., & Roba, K. T. (2022) · SAGE Open Nursing · doi:10.1177/23779608221138420 · Cited by 3 · see citing works
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da Serra, J. R., Souza, L. A. F., da Paz, M. G., Tatagiba, B. D. S. F., & Pereira, L. V. (2021) · Journal of Gerontological Nursing · doi:10.3928/00989134-20210908-05 · Cited by 2 · see citing works
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Wang, J., Kong, H., Wang, G., Wu, W., & Xu, L. (2025) · Psycho-Oncologie · doi:10.18282/po3644 · Cited by 1 · see citing works
Sutton, B. C. (2013) · Deep Blue (University of Michigan)
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Balla, D. (2013) · IOSR Journal of Humanities and Social Science · doi:10.9790/0837-1342026
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Romagnolli, L., Cória, V. R., Henrique, S., Júnior, N., Eduardo, J., Sartori, T., Romanelli, A. D. S., César, J., de Oliveira, M., Carvalho, L. G. S., et al. (2016)
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Brose, W. G., You, D. S., Cooley, C., Schmeissing, A., & Cao, F. (2025) · Springer eBooks · doi:10.1007/978-3-031-86057-7_26
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Kim, B. I., Morriss, N. J., Stauffer, T. P., Ralph, J. E., Park, C. N., Lentz, T. A., & Lau, B. C. (2025) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph22060914
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Vinaccia, S., Cudris–Torres, L., Barrios–Núñez, Á., Munive-Sánchez, S. O., & Vega, J. A. N. (2025) · Springer eBooks · doi:10.1007/978-3-031-84433-1_15
Zhang, Y., Zhao, Y., Cheng, Y., Liu, L., Wang, Z., & Wu, B. (2026) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2026.102060
- Authors
- Castro, M. M. C., Daltro, C., Kraychete, D. C., & Lopes, J.
- Affiliations
- Universidade Federal da Bahia (BR)
- Venue
- Arquivos de Neuro-Psiquiatria
- Publisher
- FapUNIFESP (SciELO)
- Published
- 2012-11
- Volume
- 70
- Issue
- 11
- Pages
- 864-868
- ISSN
- 0004-282X (ISSN-L)
- OpenAlex
- W1983184283
- Cited by
- 48
- References
- 22
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 9 · 2020: 8 · 2018: 5 · 2017: 1 · 2016: 5 · 2015: 3 · 2014: 3 · 2013: 3 · 2012: 1
- FWCI
- 2.35
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- Arquivos de Neuro-Psiquiatria (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, cc-by-nc)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Keywords
- cognitive behavioral therapy, chronic musculoskeletal pain, quality of life, depressive symptoms, anxiety, SF-36, physical limitations
- MeSH terms
- Anxiety, Depression, Female, Humans, Male, Middle Aged, Pain Measurement, Quality of Life, Socioeconomic Factors, Cognitive Behavioral Therapy, Treatment Outcome, Chronic Pain, Musculoskeletal Pain
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